HUP9700274A3 - Optically active (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)-piperazin-1-yl]-phenoxy}-butiric acid as inhibitor of celle-adhesion, preparation and use of this compound, pharmaceutical composition containing this compound - Google Patents
Optically active (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)-piperazin-1-yl]-phenoxy}-butiric acid as inhibitor of celle-adhesion, preparation and use of this compound, pharmaceutical composition containing this compoundInfo
- Publication number
- HUP9700274A3 HUP9700274A3 HU9700274A HUP9700274A HUP9700274A3 HU P9700274 A3 HUP9700274 A3 HU P9700274A3 HU 9700274 A HU9700274 A HU 9700274A HU P9700274 A HUP9700274 A HU P9700274A HU P9700274 A3 HUP9700274 A3 HU P9700274A3
- Authority
- HU
- Hungary
- Prior art keywords
- compound
- celle
- piperazin
- phenoxy
- pyridyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/457,538 US5652242A (en) | 1993-03-29 | 1995-06-01 | Heterocyclic derivatives |
GBGB9518188.9A GB9518188D0 (en) | 1995-09-07 | 1995-09-07 | Optically active derivative |
Publications (3)
Publication Number | Publication Date |
---|---|
HU9700274D0 HU9700274D0 (en) | 1997-04-28 |
HUP9700274A2 HUP9700274A2 (en) | 1999-06-28 |
HUP9700274A3 true HUP9700274A3 (en) | 2000-02-28 |
Family
ID=26307696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9700274A HUP9700274A3 (en) | 1995-06-01 | 1996-05-28 | Optically active (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)-piperazin-1-yl]-phenoxy}-butiric acid as inhibitor of celle-adhesion, preparation and use of this compound, pharmaceutical composition containing this compound |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP0796247A1 (en) |
JP (1) | JP2885941B2 (en) |
KR (1) | KR100245957B1 (en) |
AT (1) | AT406675B (en) |
AU (1) | AU710105B2 (en) |
BE (1) | BE1009520A5 (en) |
BR (1) | BR9606409A (en) |
CA (1) | CA2194397A1 (en) |
CH (1) | CH691808A5 (en) |
CZ (1) | CZ26997A3 (en) |
DE (1) | DE19680509T1 (en) |
DK (1) | DK10697A (en) |
ES (1) | ES2137886B1 (en) |
FI (1) | FI970393A (en) |
GB (1) | GB2304340B (en) |
GR (1) | GR1002702B (en) |
HU (1) | HUP9700274A3 (en) |
IE (1) | IE960405A1 (en) |
IL (1) | IL118477A0 (en) |
IT (1) | IT1290839B1 (en) |
LU (1) | LU90008B1 (en) |
MC (1) | MC2418A1 (en) |
MX (1) | MX9700379A (en) |
NL (1) | NL1003243C2 (en) |
NO (1) | NO307460B1 (en) |
NZ (1) | NZ308597A (en) |
PL (1) | PL318440A1 (en) |
SE (1) | SE510812C2 (en) |
SK (1) | SK13097A3 (en) |
TR (1) | TR199700020T1 (en) |
WO (1) | WO1996038416A1 (en) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0100158A3 (en) * | 1982-07-28 | 1985-03-27 | The Upjohn Company | (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters |
GB8609630D0 (en) * | 1986-04-19 | 1986-05-21 | Pfizer Ltd | Anti-arrhythmia agents |
GB9406143D0 (en) * | 1993-03-29 | 1994-05-18 | Zeneca Ltd | Heterocyclic derivatives |
CA2155307A1 (en) * | 1993-03-29 | 1994-10-13 | Michael Garth Wayne | Heterocyclic compounds as platelet aggregation inhibitors |
-
1996
- 1996-05-28 CZ CZ97269A patent/CZ26997A3/en unknown
- 1996-05-28 AU AU58272/96A patent/AU710105B2/en not_active Ceased
- 1996-05-28 JP JP8536281A patent/JP2885941B2/en not_active Expired - Fee Related
- 1996-05-28 KR KR1019970700532A patent/KR100245957B1/en not_active IP Right Cessation
- 1996-05-28 AT AT0900596A patent/AT406675B/en active
- 1996-05-28 DE DE19680509T patent/DE19680509T1/en not_active Withdrawn
- 1996-05-28 BR BR9606409A patent/BR9606409A/en not_active Application Discontinuation
- 1996-05-28 CA CA002194397A patent/CA2194397A1/en not_active Abandoned
- 1996-05-28 NZ NZ308597A patent/NZ308597A/en unknown
- 1996-05-28 ES ES009750006A patent/ES2137886B1/en not_active Expired - Fee Related
- 1996-05-28 GR GR960100176A patent/GR1002702B/en not_active IP Right Cessation
- 1996-05-28 PL PL96318440A patent/PL318440A1/en unknown
- 1996-05-28 GB GB9627127A patent/GB2304340B/en not_active Expired - Fee Related
- 1996-05-28 HU HU9700274A patent/HUP9700274A3/en unknown
- 1996-05-28 EP EP96919906A patent/EP0796247A1/en not_active Withdrawn
- 1996-05-28 SK SK130-97A patent/SK13097A3/en unknown
- 1996-05-28 CH CH00224/97A patent/CH691808A5/en not_active IP Right Cessation
- 1996-05-28 MX MX9700379A patent/MX9700379A/en unknown
- 1996-05-28 TR TR97/00020T patent/TR199700020T1/en unknown
- 1996-05-28 WO PCT/GB1996/001260 patent/WO1996038416A1/en not_active IP Right Cessation
- 1996-05-29 MC MC2347A patent/MC2418A1/en unknown
- 1996-05-30 IL IL11847796A patent/IL118477A0/en unknown
- 1996-05-31 BE BE9600491A patent/BE1009520A5/en not_active IP Right Cessation
- 1996-05-31 IT IT96MI001113A patent/IT1290839B1/en active IP Right Grant
- 1996-05-31 IE IE960405A patent/IE960405A1/en not_active IP Right Cessation
- 1996-05-31 NL NL1003243A patent/NL1003243C2/en not_active IP Right Cessation
-
1997
- 1997-01-22 LU LU90008A patent/LU90008B1/en active
- 1997-01-24 SE SE9700203A patent/SE510812C2/en not_active IP Right Cessation
- 1997-01-30 FI FI970393A patent/FI970393A/en unknown
- 1997-01-30 DK DK010697A patent/DK10697A/en not_active Application Discontinuation
- 1997-01-31 NO NO970437A patent/NO307460B1/en not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL116325A (en) | Substituted 4-(1,2,3,4-tetrahydro-1-naphthalenyl)-1h-imidazoles and substituted 4-(2,3-dihydro-1h-inden-1-yl)-1h-imidazoles the optically active isomers thereof and racemic mixtures thereof their preparation and pharmaceutical compositions containing them | |
EP1452172A3 (en) | Multiple unit pharmaceutical preparation | |
HUP0201275A2 (en) | Novel use of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine and its physiologically acceptable salts and pharmaceutical composition containing the compound | |
EP0433842A3 (en) | 1,2,3-triazole derivatives active as inhibitors of the enzyme hmg-coa reductase and pharmaceutical compositions containing them | |
HUP9603237A3 (en) | Crystalline hydrochloride of (r)-(-)-2-{n-[4-(1,1-dioxydo-3-oxo-2,3-dihydro-benzisothiazo-2-yl)-butyl]-amino-methyl}-chromane, process for the preparation thereof and pharmaceutical compositions containing them | |
HUP0102250A3 (en) | Compounds of unstable dipeptidyl peptidase iv inhibitors, pharmaceutical compositions comprising thereof and their use | |
AU1912197A (en) | New inhibitors of metalloprotease, process for preparing them and pharmaceutical compositions containing them | |
NO963499L (en) | Hydroxamic acid and carboxylic acid derivatives, process for their preparation and use thereof | |
FI973279A (en) | Novel farnesyltransferase inhibitors, their preparation and pharmaceutical compositions containing them | |
IL143858A (en) | 4-(aminomethyl)-piperidine benzamides, process for their preparation and pharmaceutical compositions containing them | |
GB8827390D0 (en) | Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride | |
ATE332894T1 (en) | A PYRIDINE-N-OXIDE DERIVATIVE AND A PROCESS FOR ITS IMPLEMENTATION INTO PHARMACEUTICAL ACTIVE INGREDIENTS | |
HUP0000960A3 (en) | Spray-dried paroxetine hydrochloride, process for it's preparation,use of the compound and pharmaceutical compositions containing the same | |
AU3176695A (en) | Transdermally active pharmaceutical composition containing 5-aminolaevulinic acid | |
UA41978C2 (en) | N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidine-1-yl)-ethyl]-2,2-diphenylacetamide hydrochloride, a PROCESS for the preparation thereof and a pharmaceutical composition | |
IL120984A (en) | Salts of ethyl 3-(2-(4-(4-(amino-imino-methyl) phenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl)acetylamino)-3-phenylpropionate, their preparation and pharmaceutical compositions containing them | |
HUP9700274A3 (en) | Optically active (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)-piperazin-1-yl]-phenoxy}-butiric acid as inhibitor of celle-adhesion, preparation and use of this compound, pharmaceutical composition containing this compound | |
HUP0400889A3 (en) | Processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and pharmaceutical compositions containing the compound | |
HUP9902316A3 (en) | 4-(benzo-1,3-dioxolyl)-pyrrolidine-3-carboxylic acid derivatives as endothelin antagonists and pharmaceutical compositions containing them | |
HUP9900401A3 (en) | Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases, pharmaceutical compositions containing them and their use | |
EE200100219A (en) | Esters of (+) - alpha (2,3-dimethoxyphenyl) -1- [2- (4-fluorophenyl) ethyl] -4-piperidinemethanol, process for their preparation, use and pharmaceutical composition | |
IL112604A (en) | Derivatives of (2-(ar) alkyldithio indane-2-carboxamido) tricyclic-oxobenzazepine-carboxylic acid and similar compounds useful as inhibitors of enkephalinase and ace, their preparation and pharmaceutical compositions containing them | |
GB9610093D0 (en) | (-)-(3R)-methyl-4-[4-[4-(4-pyridyl) piperazin-1-yl] phenoxy] butyric acid | |
ZA964509B (en) | (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy}butyric acid | |
FR2734818B1 (en) | (-) - (3R) -3-METHYL-4- {4- [4- (4-PYRIDYL) PIPERAZINE-1-YL- PHENOXY} -BUTYRIC ACID, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME |