PL318440A1 - (-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor - Google Patents

(-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor

Info

Publication number
PL318440A1
PL318440A1 PL96318440A PL31844096A PL318440A1 PL 318440 A1 PL318440 A1 PL 318440A1 PL 96318440 A PL96318440 A PL 96318440A PL 31844096 A PL31844096 A PL 31844096A PL 318440 A1 PL318440 A1 PL 318440A1
Authority
PL
Poland
Prior art keywords
piperazin
phenoxy
pyridyl
methyl
butyric acid
Prior art date
Application number
PL96318440A
Inventor
Stuart Dennett Mills
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of PL318440A1 publication Critical patent/PL318440A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
PL96318440A 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor PL318440A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative

Publications (1)

Publication Number Publication Date
PL318440A1 true PL318440A1 (en) 1997-06-09

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96318440A PL318440A1 (en) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor

Country Status (31)

Country Link
EP (1) EP0796247A1 (en)
JP (1) JP2885941B2 (en)
KR (1) KR100245957B1 (en)
AT (1) AT406675B (en)
AU (1) AU710105B2 (en)
BE (1) BE1009520A5 (en)
BR (1) BR9606409A (en)
CA (1) CA2194397A1 (en)
CH (1) CH691808A5 (en)
CZ (1) CZ26997A3 (en)
DE (1) DE19680509T1 (en)
DK (1) DK10697A (en)
ES (1) ES2137886B1 (en)
FI (1) FI970393A (en)
GB (1) GB2304340B (en)
GR (1) GR1002702B (en)
HU (1) HUP9700274A3 (en)
IE (1) IE960405A1 (en)
IL (1) IL118477A0 (en)
IT (1) IT1290839B1 (en)
LU (1) LU90008B1 (en)
MC (1) MC2418A1 (en)
MX (1) MX9700379A (en)
NL (1) NL1003243C2 (en)
NO (1) NO307460B1 (en)
NZ (1) NZ308597A (en)
PL (1) PL318440A1 (en)
SE (1) SE510812C2 (en)
SK (1) SK13097A3 (en)
TR (1) TR199700020T1 (en)
WO (1) WO1996038416A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
ZW4194A1 (en) * 1993-03-29 1994-12-21 Zeneca Ltd Heterocyclic compounds
PT825184E (en) * 1993-03-29 2001-11-30 Astrazeneca Ab HETEROCYCLIC DERIVATIVES AS PLATELET INHIBITORS

Also Published As

Publication number Publication date
NO307460B1 (en) 2000-04-10
SK13097A3 (en) 1997-08-06
AU710105B2 (en) 1999-09-16
SE9700203D0 (en) 1997-01-24
IT1290839B1 (en) 1998-12-14
JPH09512836A (en) 1997-12-22
CA2194397A1 (en) 1996-12-05
NO970437L (en) 1997-02-20
GB2304340B (en) 1998-07-29
NO970437D0 (en) 1997-01-31
AT406675B (en) 2000-07-25
NZ308597A (en) 1998-11-25
ES2137886A1 (en) 1999-12-16
JP2885941B2 (en) 1999-04-26
ITMI961113A0 (en) 1996-05-31
EP0796247A1 (en) 1997-09-24
GB2304340A (en) 1997-03-19
HUP9700274A3 (en) 2000-02-28
ES2137886B1 (en) 2000-08-16
ATA900596A (en) 1999-12-15
HU9700274D0 (en) 1997-04-28
NL1003243C2 (en) 1996-12-04
GB9627127D0 (en) 1997-02-19
FI970393A0 (en) 1997-01-30
GR1002702B (en) 1997-05-22
ITMI961113A1 (en) 1997-12-01
TR199700020T1 (en) 1997-04-22
DK10697A (en) 1997-04-01
BR9606409A (en) 1997-09-30
SE510812C2 (en) 1999-06-28
LU90008B1 (en) 1997-04-16
SE9700203L (en) 1997-01-24
IL118477A0 (en) 1996-09-12
WO1996038416A1 (en) 1996-12-05
FI970393A (en) 1997-01-30
AU5827296A (en) 1996-12-18
CH691808A5 (en) 2001-10-31
CZ26997A3 (en) 1997-08-13
KR100245957B1 (en) 2000-04-01
IE960405A1 (en) 1996-12-11
HUP9700274A2 (en) 1999-06-28
BE1009520A5 (en) 1997-04-01
DE19680509T1 (en) 1997-12-04
MX9700379A (en) 1997-04-30
KR970704689A (en) 1997-09-06
MC2418A1 (en) 1997-05-23

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