AU6049796A - Lysyloxidase inhibitors - Google Patents

Lysyloxidase inhibitors

Info

Publication number
AU6049796A
AU6049796A AU60497/96A AU6049796A AU6049796A AU 6049796 A AU6049796 A AU 6049796A AU 60497/96 A AU60497/96 A AU 60497/96A AU 6049796 A AU6049796 A AU 6049796A AU 6049796 A AU6049796 A AU 6049796A
Authority
AU
Australia
Prior art keywords
lysyloxidase
inhibitors
lysyloxidase inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU60497/96A
Inventor
Carl S. Apstein
Edward G Bernstine
Herbert M. Kagan
Kaliappanadar Nellaiappan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FIBROMED Inc
Boston University
Original Assignee
FIBROMED Inc
Boston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FIBROMED Inc, Boston University filed Critical FIBROMED Inc
Publication of AU6049796A publication Critical patent/AU6049796A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU60497/96A 1995-06-07 1996-06-06 Lysyloxidase inhibitors Abandoned AU6049796A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47306195A 1995-06-07 1995-06-07
US473061 1995-06-07
PCT/US1996/009102 WO1996040746A1 (en) 1995-06-07 1996-06-06 Lysyloxidase inhibitors

Publications (1)

Publication Number Publication Date
AU6049796A true AU6049796A (en) 1996-12-30

Family

ID=23878032

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60497/96A Abandoned AU6049796A (en) 1995-06-07 1996-06-06 Lysyloxidase inhibitors

Country Status (2)

Country Link
AU (1) AU6049796A (en)
WO (1) WO1996040746A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2782007B1 (en) * 1998-08-05 2001-02-23 Centre Nat Rech Scient USE OF CALIX (N) ARENES FOR THE TREATMENT OF FIBROTIC DISEASES
GB9924195D0 (en) * 1999-10-13 1999-12-15 Univ Nottingham N-Acyl homoserine lactones for the treatment of cardiac tachyarrhythmias Ischaemic heart disease or congestive heart failure
US20030114410A1 (en) 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
GB0524991D0 (en) * 2005-12-08 2006-01-18 Ge Healthcare Ltd Novel imaging agents for fibrosis
JP5659014B2 (en) 2007-08-02 2015-01-28 ジリード バイオロジクス，インク． Methods and compositions for treatment and diagnosis of fibrosis, tumor invasion, angiogenesis and metastasis
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
BR112012008054A2 (en) 2009-08-21 2017-05-23 Gilead Biologics Inc catalytic domains of lysyl oxidase and loxl2
WO2024002457A1 (en) * 2022-06-27 2024-01-04 Centre National De La Recherche Scientifique Polyamides functionalized with chains containing thiol functions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3037513C2 (en) * 1980-10-03 1983-05-05 Steffan, Wolfgang, 8425 Neustadt Collagen wound dressing
IT1246766B (en) * 1990-11-12 1994-11-26 Medea Res Srl -
US5326760A (en) * 1992-06-29 1994-07-05 Glaxo, Inc. Aminobutanoic acid compounds having metalloprotease inhibiting properties
GB2276618A (en) * 1993-03-29 1994-10-05 Merck & Co Inc Inhibitors of isoprenylated protein endoprotease

Also Published As

Publication number Publication date
WO1996040746A1 (en) 1996-12-19

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