ATA900596A - (-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor - Google Patents

(-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor

Info

Publication number
ATA900596A
ATA900596A AT0900596A AT900596A ATA900596A AT A900596 A ATA900596 A AT A900596A AT 0900596 A AT0900596 A AT 0900596A AT 900596 A AT900596 A AT 900596A AT A900596 A ATA900596 A AT A900596A
Authority
AT
Austria
Prior art keywords
piperazin
phenoxy
pyridyl
methyl
cellular adhesion
Prior art date
Application number
AT0900596A
Other languages
English (en)
Other versions
AT406675B (de
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of ATA900596A publication Critical patent/ATA900596A/de
Application granted granted Critical
Publication of AT406675B publication Critical patent/AT406675B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
AT0900596A 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor AT406675B (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative
PCT/GB1996/001260 WO1996038416A1 (en) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Publications (2)

Publication Number Publication Date
ATA900596A true ATA900596A (de) 1999-12-15
AT406675B AT406675B (de) 2000-07-25

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0900596A AT406675B (de) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor

Country Status (31)

Country Link
EP (1) EP0796247A1 (de)
JP (1) JP2885941B2 (de)
KR (1) KR100245957B1 (de)
AT (1) AT406675B (de)
AU (1) AU710105B2 (de)
BE (1) BE1009520A5 (de)
BR (1) BR9606409A (de)
CA (1) CA2194397A1 (de)
CH (1) CH691808A5 (de)
CZ (1) CZ26997A3 (de)
DE (1) DE19680509T1 (de)
DK (1) DK10697A (de)
ES (1) ES2137886B1 (de)
FI (1) FI970393A (de)
GB (1) GB2304340B (de)
GR (1) GR1002702B (de)
HU (1) HUP9700274A3 (de)
IE (1) IE960405A1 (de)
IL (1) IL118477A0 (de)
IT (1) IT1290839B1 (de)
LU (1) LU90008B1 (de)
MC (1) MC2418A1 (de)
MX (1) MX9700379A (de)
NL (1) NL1003243C2 (de)
NO (1) NO307460B1 (de)
NZ (1) NZ308597A (de)
PL (1) PL318440A1 (de)
SE (1) SE510812C2 (de)
SK (1) SK13097A3 (de)
TR (1) TR199700020T1 (de)
WO (1) WO1996038416A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (de) * 1982-07-28 1985-03-27 The Upjohn Company (3-Pyridinyl)-heteroalkarylalkanole, ihre Alkansäuren und ihre Ester
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
ZW4194A1 (en) * 1993-03-29 1994-12-21 Zeneca Ltd Heterocyclic compounds
PT825184E (pt) * 1993-03-29 2001-11-30 Astrazeneca Ab Derivados heterociclicos como inibidores de agregacao de plaquetas

Also Published As

Publication number Publication date
NO307460B1 (no) 2000-04-10
SK13097A3 (en) 1997-08-06
AU710105B2 (en) 1999-09-16
SE9700203D0 (sv) 1997-01-24
IT1290839B1 (it) 1998-12-14
JPH09512836A (ja) 1997-12-22
PL318440A1 (en) 1997-06-09
CA2194397A1 (en) 1996-12-05
NO970437L (no) 1997-02-20
GB2304340B (en) 1998-07-29
NO970437D0 (no) 1997-01-31
AT406675B (de) 2000-07-25
NZ308597A (en) 1998-11-25
ES2137886A1 (es) 1999-12-16
JP2885941B2 (ja) 1999-04-26
ITMI961113A0 (it) 1996-05-31
EP0796247A1 (de) 1997-09-24
GB2304340A (en) 1997-03-19
HUP9700274A3 (en) 2000-02-28
ES2137886B1 (es) 2000-08-16
HU9700274D0 (en) 1997-04-28
NL1003243C2 (nl) 1996-12-04
GB9627127D0 (en) 1997-02-19
FI970393A0 (fi) 1997-01-30
GR1002702B (el) 1997-05-22
ITMI961113A1 (it) 1997-12-01
TR199700020T1 (tr) 1997-04-22
DK10697A (da) 1997-04-01
BR9606409A (pt) 1997-09-30
SE510812C2 (sv) 1999-06-28
LU90008B1 (fr) 1997-04-16
SE9700203L (sv) 1997-01-24
IL118477A0 (en) 1996-09-12
WO1996038416A1 (en) 1996-12-05
FI970393A (fi) 1997-01-30
AU5827296A (en) 1996-12-18
CH691808A5 (de) 2001-10-31
CZ26997A3 (en) 1997-08-13
KR100245957B1 (ko) 2000-04-01
IE960405A1 (en) 1996-12-11
HUP9700274A2 (hu) 1999-06-28
BE1009520A5 (fr) 1997-04-01
DE19680509T1 (de) 1997-12-04
MX9700379A (es) 1997-04-30
KR970704689A (ko) 1997-09-06
MC2418A1 (fr) 1997-05-23

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