MX9700379A - Acido(-)-(3r)-3-metil-4-(4-(4-(4-piridil)piperazin-1-il)-fenoxi)butirico como inhibidor de la adhesion celular. - Google Patents
Acido(-)-(3r)-3-metil-4-(4-(4-(4-piridil)piperazin-1-il)-fenoxi)butirico como inhibidor de la adhesion celular.Info
- Publication number
- MX9700379A MX9700379A MX9700379A MX9700379A MX9700379A MX 9700379 A MX9700379 A MX 9700379A MX 9700379 A MX9700379 A MX 9700379A MX 9700379 A MX9700379 A MX 9700379A MX 9700379 A MX9700379 A MX 9700379A
- Authority
- MX
- Mexico
- Prior art keywords
- piperazin
- phenoxy
- pyridyl
- methyl
- butyric acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
Se describe un nuevo compuesto opticamente activo de ácido (-)-(3R)-3-metil-4-{4-[4-4-piridil)-piperazil-1-il ]fenxoxi)butírico y sales, ésteres, amidas o solvatos farmacéuticamente aceptables del mismo. Procesos para la preparacion del compuesto, composiciones farmacéuticas que contienen el compuesto y su uso para inhibir la adhesion celular, por ejemplo la agregacion de plaquetas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/457,538 US5652242A (en) | 1993-03-29 | 1995-06-01 | Heterocyclic derivatives |
GBGB9518188.9A GB9518188D0 (en) | 1995-09-07 | 1995-09-07 | Optically active derivative |
PCT/GB1996/001260 WO1996038416A1 (en) | 1995-06-01 | 1996-05-28 | (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9700379A true MX9700379A (es) | 1997-04-30 |
Family
ID=26307696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9700379A MX9700379A (es) | 1995-06-01 | 1996-05-28 | Acido(-)-(3r)-3-metil-4-(4-(4-(4-piridil)piperazin-1-il)-fenoxi)butirico como inhibidor de la adhesion celular. |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP0796247A1 (es) |
JP (1) | JP2885941B2 (es) |
KR (1) | KR100245957B1 (es) |
AT (1) | AT406675B (es) |
AU (1) | AU710105B2 (es) |
BE (1) | BE1009520A5 (es) |
BR (1) | BR9606409A (es) |
CA (1) | CA2194397A1 (es) |
CH (1) | CH691808A5 (es) |
CZ (1) | CZ26997A3 (es) |
DE (1) | DE19680509T1 (es) |
DK (1) | DK10697A (es) |
ES (1) | ES2137886B1 (es) |
FI (1) | FI970393A (es) |
GB (1) | GB2304340B (es) |
GR (1) | GR1002702B (es) |
HU (1) | HUP9700274A3 (es) |
IE (1) | IE960405A1 (es) |
IL (1) | IL118477A0 (es) |
IT (1) | IT1290839B1 (es) |
LU (1) | LU90008B1 (es) |
MC (1) | MC2418A1 (es) |
MX (1) | MX9700379A (es) |
NL (1) | NL1003243C2 (es) |
NO (1) | NO307460B1 (es) |
NZ (1) | NZ308597A (es) |
PL (1) | PL318440A1 (es) |
SE (1) | SE510812C2 (es) |
SK (1) | SK13097A3 (es) |
TR (1) | TR199700020T1 (es) |
WO (1) | WO1996038416A1 (es) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0100158A3 (en) * | 1982-07-28 | 1985-03-27 | The Upjohn Company | (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters |
GB8609630D0 (en) * | 1986-04-19 | 1986-05-21 | Pfizer Ltd | Anti-arrhythmia agents |
ZW4194A1 (en) * | 1993-03-29 | 1994-12-21 | Zeneca Ltd | Heterocyclic compounds |
PT825184E (pt) * | 1993-03-29 | 2001-11-30 | Astrazeneca Ab | Derivados heterociclicos como inibidores de agregacao de plaquetas |
-
1996
- 1996-05-28 JP JP8536281A patent/JP2885941B2/ja not_active Expired - Fee Related
- 1996-05-28 ES ES009750006A patent/ES2137886B1/es not_active Expired - Fee Related
- 1996-05-28 NZ NZ308597A patent/NZ308597A/en unknown
- 1996-05-28 GB GB9627127A patent/GB2304340B/en not_active Expired - Fee Related
- 1996-05-28 AT AT0900596A patent/AT406675B/de active
- 1996-05-28 TR TR97/00020T patent/TR199700020T1/xx unknown
- 1996-05-28 SK SK130-97A patent/SK13097A3/sk unknown
- 1996-05-28 HU HU9700274A patent/HUP9700274A3/hu unknown
- 1996-05-28 GR GR960100176A patent/GR1002702B/el not_active IP Right Cessation
- 1996-05-28 DE DE19680509T patent/DE19680509T1/de not_active Withdrawn
- 1996-05-28 CZ CZ97269A patent/CZ26997A3/cs unknown
- 1996-05-28 MX MX9700379A patent/MX9700379A/es unknown
- 1996-05-28 WO PCT/GB1996/001260 patent/WO1996038416A1/en not_active IP Right Cessation
- 1996-05-28 AU AU58272/96A patent/AU710105B2/en not_active Ceased
- 1996-05-28 BR BR9606409A patent/BR9606409A/pt not_active Application Discontinuation
- 1996-05-28 CH CH00224/97A patent/CH691808A5/de not_active IP Right Cessation
- 1996-05-28 PL PL96318440A patent/PL318440A1/xx unknown
- 1996-05-28 CA CA002194397A patent/CA2194397A1/en not_active Abandoned
- 1996-05-28 EP EP96919906A patent/EP0796247A1/en not_active Withdrawn
- 1996-05-28 KR KR1019970700532A patent/KR100245957B1/ko not_active IP Right Cessation
- 1996-05-29 MC MC2347A patent/MC2418A1/xx unknown
- 1996-05-30 IL IL11847796A patent/IL118477A0/xx unknown
- 1996-05-31 BE BE9600491A patent/BE1009520A5/fr not_active IP Right Cessation
- 1996-05-31 IE IE960405A patent/IE960405A1/en not_active IP Right Cessation
- 1996-05-31 NL NL1003243A patent/NL1003243C2/xx not_active IP Right Cessation
- 1996-05-31 IT IT96MI001113A patent/IT1290839B1/it active IP Right Grant
-
1997
- 1997-01-22 LU LU90008A patent/LU90008B1/fr active
- 1997-01-24 SE SE9700203A patent/SE510812C2/sv not_active IP Right Cessation
- 1997-01-30 FI FI970393A patent/FI970393A/fi unknown
- 1997-01-30 DK DK010697A patent/DK10697A/da not_active Application Discontinuation
- 1997-01-31 NO NO970437A patent/NO307460B1/no not_active IP Right Cessation
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