CH667457A5 - Verfahren zur herstellung von substituierten 7-oxomitosanen. - Google Patents

Verfahren zur herstellung von substituierten 7-oxomitosanen. Download PDF

Info

Publication number
CH667457A5
CH667457A5 CH870/88A CH87088A CH667457A5 CH 667457 A5 CH667457 A5 CH 667457A5 CH 870/88 A CH870/88 A CH 870/88A CH 87088 A CH87088 A CH 87088A CH 667457 A5 CH667457 A5 CH 667457A5
Authority
CH
Switzerland
Prior art keywords
formula
triazene
reaction
methylene chloride
compound
Prior art date
Application number
CH870/88A
Other languages
German (de)
English (en)
Inventor
Dolatrai Mohanlal Vyas
Terrence William Doyle
Richard A Partyka
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH667457A5 publication Critical patent/CH667457A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH870/88A 1984-09-04 1985-09-03 Verfahren zur herstellung von substituierten 7-oxomitosanen. CH667457A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64688884A 1984-09-04 1984-09-04
US74457085A 1985-06-17 1985-06-17

Publications (1)

Publication Number Publication Date
CH667457A5 true CH667457A5 (de) 1988-10-14

Family

ID=27095036

Family Applications (2)

Application Number Title Priority Date Filing Date
CH3796/85A CH667094A5 (de) 1984-09-04 1985-09-03 Substituierte 7-oxomitosane.
CH870/88A CH667457A5 (de) 1984-09-04 1985-09-03 Verfahren zur herstellung von substituierten 7-oxomitosanen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH3796/85A CH667094A5 (de) 1984-09-04 1985-09-03 Substituierte 7-oxomitosane.

Country Status (24)

Country Link
JP (1) JPS61112078A (el)
KR (2) KR900008570B1 (el)
AT (1) AT394723B (el)
AU (1) AU581673B2 (el)
BE (1) BE903169A (el)
CA (2) CA1291293C (el)
CH (2) CH667094A5 (el)
CY (2) CY1586A (el)
DE (1) DE3531453C2 (el)
DK (1) DK169478B1 (el)
ES (3) ES8702408A1 (el)
FI (1) FI80700C (el)
FR (1) FR2569696B1 (el)
GB (2) GB2164038B (el)
GR (1) GR852118B (el)
HK (2) HK22491A (el)
HU (1) HU195658B (el)
IE (1) IE58720B1 (el)
IT (1) IT1209660B (el)
LU (1) LU86062A1 (el)
NL (1) NL8502383A (el)
NO (1) NO169441C (el)
PT (1) PT81083B (el)
SE (2) SE465929B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
US4888341A (en) * 1984-09-04 1989-12-19 University Patents, Inc. 6-substituted mitomycin analogs
IL86665A0 (en) * 1987-06-12 1988-11-30 Bristol Myers Co Mitomycin analogs
ZA886812B (en) * 1987-11-23 1989-07-26 Bristol Myers Co Anti-tumor prodrugs
US5023253A (en) * 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5075454A (en) * 1990-03-08 1991-12-24 Bristol-Myers Squibb Company 7-(diphenylmethyl)oxy-9a-methoxymitosane

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3306821A (en) * 1962-09-04 1967-02-28 Upjohn Co Porfiromycin derivatives and method of making same
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
JPS59175493A (ja) * 1983-03-25 1984-10-04 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
DE3376114D1 (en) * 1982-12-07 1988-05-05 Kyowa Hakko Kogyo Kk Mitomycin analogues
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
KR840008362A (ko) * 1983-04-11 1984-12-14 사무엘 제이. 두보프 아미노 이황산염
US4888341A (en) * 1984-09-04 1989-12-19 University Patents, Inc. 6-substituted mitomycin analogs

Also Published As

Publication number Publication date
FR2569696B1 (fr) 1991-12-20
ES8702408A1 (es) 1986-12-16
FR2569696A1 (fr) 1986-03-07
SE9004157L (sv) 1992-06-28
HK22391A (en) 1991-04-04
FI80700B (fi) 1990-03-30
CA1254892A (en) 1989-05-30
HK22491A (en) 1991-04-04
NO169441B (no) 1992-03-16
CY1585A (en) 1992-04-03
AU581673B2 (en) 1989-03-02
ES553548A0 (es) 1987-06-16
IT1209660B (it) 1989-08-30
IT8522059A0 (it) 1985-09-03
HU195658B (en) 1988-06-28
CY1586A (en) 1992-04-03
GB2196006A (en) 1988-04-20
SE9004157D0 (sv) 1990-12-27
NL8502383A (nl) 1986-04-01
NO853435L (no) 1986-03-05
FI853338A0 (fi) 1985-08-30
ES8706326A1 (es) 1987-06-16
IE852174L (en) 1986-03-04
BE903169A (fr) 1986-03-03
DK401385A (da) 1986-03-05
GB8521816D0 (en) 1985-10-09
SE8504093D0 (sv) 1985-09-03
SE465929B (sv) 1991-11-18
IE58720B1 (en) 1993-11-03
LU86062A1 (fr) 1986-03-03
CH667094A5 (de) 1988-09-15
DE3531453A1 (de) 1986-03-13
ES546687A0 (es) 1986-12-16
GB8726516D0 (en) 1987-12-16
FI80700C (fi) 1990-07-10
PT81083B (pt) 1988-01-22
GB2164038A (en) 1986-03-12
AT394723B (de) 1992-06-10
AU4571685A (en) 1986-03-13
ES8706327A1 (es) 1987-06-16
CA1291293C (en) 1991-10-22
GR852118B (el) 1986-01-07
ES553549A0 (es) 1987-06-16
KR900008570B1 (ko) 1990-11-24
NO169441C (no) 1992-06-24
GB2164038B (en) 1988-11-09
PT81083A (en) 1985-10-01
DE3531453C2 (de) 1996-07-18
GB2196006B (en) 1988-11-09
DK169478B1 (da) 1994-11-07
KR900008840B1 (ko) 1990-11-30
FI853338L (fi) 1986-03-05
HUT38942A (en) 1986-07-28
KR860002507A (ko) 1986-04-26
JPH0560469B2 (el) 1993-09-02
ATA258985A (de) 1991-11-15
DK401385D0 (da) 1985-09-03
JPS61112078A (ja) 1986-05-30
SE8504093L (sv) 1986-03-05

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