GB2196006B - Preparation of pyrroloindole derivatives - Google Patents

Preparation of pyrroloindole derivatives

Info

Publication number
GB2196006B
GB2196006B GB08726516A GB8726516A GB2196006B GB 2196006 B GB2196006 B GB 2196006B GB 08726516 A GB08726516 A GB 08726516A GB 8726516 A GB8726516 A GB 8726516A GB 2196006 B GB2196006 B GB 2196006B
Authority
GB
United Kingdom
Prior art keywords
preparation
pyrroloindole
derivatives
pyrroloindole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08726516A
Other versions
GB2196006A (en
GB8726516D0 (en
Inventor
Dolatrai Mohanlal Vyas
Terrence William Doyle
Richard A Partyka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB8726516D0 publication Critical patent/GB8726516D0/en
Publication of GB2196006A publication Critical patent/GB2196006A/en
Application granted granted Critical
Publication of GB2196006B publication Critical patent/GB2196006B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB08726516A 1984-09-04 1987-11-12 Preparation of pyrroloindole derivatives Expired GB2196006B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64688884A 1984-09-04 1984-09-04
US74457085A 1985-06-17 1985-06-17

Publications (3)

Publication Number Publication Date
GB8726516D0 GB8726516D0 (en) 1987-12-16
GB2196006A GB2196006A (en) 1988-04-20
GB2196006B true GB2196006B (en) 1988-11-09

Family

ID=27095036

Family Applications (2)

Application Number Title Priority Date Filing Date
GB08521816A Expired GB2164038B (en) 1984-09-04 1985-09-03 Pyrroloindole derivatives
GB08726516A Expired GB2196006B (en) 1984-09-04 1987-11-12 Preparation of pyrroloindole derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB08521816A Expired GB2164038B (en) 1984-09-04 1985-09-03 Pyrroloindole derivatives

Country Status (24)

Country Link
JP (1) JPS61112078A (en)
KR (2) KR900008570B1 (en)
AT (1) AT394723B (en)
AU (1) AU581673B2 (en)
BE (1) BE903169A (en)
CA (2) CA1291293C (en)
CH (2) CH667457A5 (en)
CY (2) CY1585A (en)
DE (1) DE3531453C2 (en)
DK (1) DK169478B1 (en)
ES (3) ES8702408A1 (en)
FI (1) FI80700C (en)
FR (1) FR2569696B1 (en)
GB (2) GB2164038B (en)
GR (1) GR852118B (en)
HK (2) HK22391A (en)
HU (1) HU195658B (en)
IE (1) IE58720B1 (en)
IT (1) IT1209660B (en)
LU (1) LU86062A1 (en)
NL (1) NL8502383A (en)
NO (1) NO169441C (en)
PT (1) PT81083B (en)
SE (2) SE465929B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
US4888341A (en) * 1984-09-04 1989-12-19 University Patents, Inc. 6-substituted mitomycin analogs
IL86665A0 (en) * 1987-06-12 1988-11-30 Bristol Myers Co Mitomycin analogs
ZA886812B (en) * 1987-11-23 1989-07-26 Bristol Myers Co Anti-tumor prodrugs
US5023253A (en) * 1987-12-21 1991-06-11 University Patents, Inc. 6-substituted mitomycin analogs
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5075454A (en) * 1990-03-08 1991-12-24 Bristol-Myers Squibb Company 7-(diphenylmethyl)oxy-9a-methoxymitosane

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3306821A (en) * 1962-09-04 1967-02-28 Upjohn Co Porfiromycin derivatives and method of making same
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
DE116208T1 (en) * 1982-12-07 1985-02-28 Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo MITOMYCIN ANALOGS.
JPS59175493A (en) * 1983-03-25 1984-10-04 Kyowa Hakko Kogyo Co Ltd Mitomycin derivative and its preparation
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
KR840008362A (en) * 1983-04-11 1984-12-14 사무엘 제이. 두보프 Amino disulfate
US4888341A (en) * 1984-09-04 1989-12-19 University Patents, Inc. 6-substituted mitomycin analogs

Also Published As

Publication number Publication date
DE3531453A1 (en) 1986-03-13
DE3531453C2 (en) 1996-07-18
HU195658B (en) 1988-06-28
SE465929B (en) 1991-11-18
SE8504093L (en) 1986-03-05
NO169441C (en) 1992-06-24
SE9004157D0 (en) 1990-12-27
AT394723B (en) 1992-06-10
GB2196006A (en) 1988-04-20
KR900008570B1 (en) 1990-11-24
PT81083A (en) 1985-10-01
ES8706327A1 (en) 1987-06-16
IT8522059A0 (en) 1985-09-03
CY1586A (en) 1992-04-03
SE8504093D0 (en) 1985-09-03
DK169478B1 (en) 1994-11-07
DK401385D0 (en) 1985-09-03
FI853338A0 (en) 1985-08-30
SE9004157L (en) 1992-06-28
BE903169A (en) 1986-03-03
GB2164038A (en) 1986-03-12
GB8521816D0 (en) 1985-10-09
FI80700B (en) 1990-03-30
KR860002507A (en) 1986-04-26
NO169441B (en) 1992-03-16
PT81083B (en) 1988-01-22
CH667457A5 (en) 1988-10-14
IE852174L (en) 1986-03-04
CA1291293C (en) 1991-10-22
CA1254892A (en) 1989-05-30
ES546687A0 (en) 1986-12-16
FR2569696A1 (en) 1986-03-07
KR900008840B1 (en) 1990-11-30
CH667094A5 (en) 1988-09-15
DK401385A (en) 1986-03-05
CY1585A (en) 1992-04-03
ES8706326A1 (en) 1987-06-16
FI853338L (en) 1986-03-05
HUT38942A (en) 1986-07-28
JPS61112078A (en) 1986-05-30
ES553549A0 (en) 1987-06-16
ATA258985A (en) 1991-11-15
AU4571685A (en) 1986-03-13
NO853435L (en) 1986-03-05
ES8702408A1 (en) 1986-12-16
ES553548A0 (en) 1987-06-16
GR852118B (en) 1986-01-07
HK22391A (en) 1991-04-04
JPH0560469B2 (en) 1993-09-02
LU86062A1 (en) 1986-03-03
FI80700C (en) 1990-07-10
GB2164038B (en) 1988-11-09
GB8726516D0 (en) 1987-12-16
FR2569696B1 (en) 1991-12-20
IE58720B1 (en) 1993-11-03
NL8502383A (en) 1986-04-01
AU581673B2 (en) 1989-03-02
IT1209660B (en) 1989-08-30
HK22491A (en) 1991-04-04

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960903