BE903169A - 7-oxomitosanes substitues - Google Patents
7-oxomitosanes substituesInfo
- Publication number
- BE903169A BE903169A BE0/215535A BE215535A BE903169A BE 903169 A BE903169 A BE 903169A BE 0/215535 A BE0/215535 A BE 0/215535A BE 215535 A BE215535 A BE 215535A BE 903169 A BE903169 A BE 903169A
- Authority
- BE
- Belgium
- Prior art keywords
- radical
- oxomitosanes
- substituted
- alk1
- dihydroxyethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Nouveaux analogues de la mitomycine contenant un radical disulfure de formule II ou III où notamment, Alk1 et Alk2 représentent un radical éthylène, R1 représente un atome d'hydrogène, R3 représente un radical acétylamino, acétyloxy, 1,2-dihydroxyéthyle ou carboxyle, et R4 représente un radical phényle, 4-nitrophényle, 4-méthoxyphényle, 4-aminophényle, ou 2-carboxyphényle.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64688884A | 1984-09-04 | 1984-09-04 | |
US74457085A | 1985-06-17 | 1985-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
BE903169A true BE903169A (fr) | 1986-03-03 |
Family
ID=27095036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/215535A BE903169A (fr) | 1984-09-04 | 1985-09-03 | 7-oxomitosanes substitues |
Country Status (24)
Country | Link |
---|---|
JP (1) | JPS61112078A (fr) |
KR (2) | KR900008570B1 (fr) |
AT (1) | AT394723B (fr) |
AU (1) | AU581673B2 (fr) |
BE (1) | BE903169A (fr) |
CA (2) | CA1291293C (fr) |
CH (2) | CH667094A5 (fr) |
CY (2) | CY1586A (fr) |
DE (1) | DE3531453C2 (fr) |
DK (1) | DK169478B1 (fr) |
ES (3) | ES8702408A1 (fr) |
FI (1) | FI80700C (fr) |
FR (1) | FR2569696B1 (fr) |
GB (2) | GB2164038B (fr) |
GR (1) | GR852118B (fr) |
HK (2) | HK22491A (fr) |
HU (1) | HU195658B (fr) |
IE (1) | IE58720B1 (fr) |
IT (1) | IT1209660B (fr) |
LU (1) | LU86062A1 (fr) |
NL (1) | NL8502383A (fr) |
NO (1) | NO169441C (fr) |
PT (1) | PT81083B (fr) |
SE (2) | SE465929B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4803212A (en) * | 1983-04-11 | 1989-02-07 | Bristol-Myers Company | Amino disulfides |
US4888341A (en) * | 1984-09-04 | 1989-12-19 | University Patents, Inc. | 6-substituted mitomycin analogs |
IL86665A0 (en) * | 1987-06-12 | 1988-11-30 | Bristol Myers Co | Mitomycin analogs |
ZA886812B (en) * | 1987-11-23 | 1989-07-26 | Bristol Myers Co | Anti-tumor prodrugs |
US5023253A (en) * | 1987-12-21 | 1991-06-11 | University Patents, Inc. | 6-substituted mitomycin analogs |
US5175303A (en) * | 1990-03-08 | 1992-12-29 | Bristol-Myers Squibb Company | Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane |
US5075454A (en) * | 1990-03-08 | 1991-12-24 | Bristol-Myers Squibb Company | 7-(diphenylmethyl)oxy-9a-methoxymitosane |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3306821A (en) * | 1962-09-04 | 1967-02-28 | Upjohn Co | Porfiromycin derivatives and method of making same |
US4487769A (en) * | 1982-06-04 | 1984-12-11 | Bristol-Myers Company | Amidines |
JPS59175493A (ja) * | 1983-03-25 | 1984-10-04 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
DE3376114D1 (en) * | 1982-12-07 | 1988-05-05 | Kyowa Hakko Kogyo Kk | Mitomycin analogues |
US4803212A (en) * | 1983-04-11 | 1989-02-07 | Bristol-Myers Company | Amino disulfides |
KR840008362A (ko) * | 1983-04-11 | 1984-12-14 | 사무엘 제이. 두보프 | 아미노 이황산염 |
US4888341A (en) * | 1984-09-04 | 1989-12-19 | University Patents, Inc. | 6-substituted mitomycin analogs |
-
1985
- 1985-08-02 AU AU45716/85A patent/AU581673B2/en not_active Ceased
- 1985-08-30 FR FR858512952A patent/FR2569696B1/fr not_active Expired - Fee Related
- 1985-08-30 FI FI853338A patent/FI80700C/fi not_active IP Right Cessation
- 1985-08-30 LU LU86062A patent/LU86062A1/fr unknown
- 1985-08-30 NL NL8502383A patent/NL8502383A/nl not_active Application Discontinuation
- 1985-09-02 KR KR1019850006404A patent/KR900008570B1/ko not_active IP Right Cessation
- 1985-09-02 GR GR852118A patent/GR852118B/el unknown
- 1985-09-02 NO NO853435A patent/NO169441C/no unknown
- 1985-09-03 PT PT81083A patent/PT81083B/pt not_active IP Right Cessation
- 1985-09-03 IE IE217485A patent/IE58720B1/en not_active IP Right Cessation
- 1985-09-03 GB GB08521816A patent/GB2164038B/en not_active Expired
- 1985-09-03 HU HU853335A patent/HU195658B/hu not_active IP Right Cessation
- 1985-09-03 SE SE8504093A patent/SE465929B/sv not_active IP Right Cessation
- 1985-09-03 ES ES546687A patent/ES8702408A1/es not_active Expired
- 1985-09-03 CH CH3796/85A patent/CH667094A5/de not_active IP Right Cessation
- 1985-09-03 DE DE3531453A patent/DE3531453C2/de not_active Expired - Fee Related
- 1985-09-03 IT IT8522059A patent/IT1209660B/it active
- 1985-09-03 CA CA000489937A patent/CA1291293C/fr not_active Expired - Lifetime
- 1985-09-03 BE BE0/215535A patent/BE903169A/fr not_active IP Right Cessation
- 1985-09-03 CH CH870/88A patent/CH667457A5/de not_active IP Right Cessation
- 1985-09-03 DK DK401385A patent/DK169478B1/da active
- 1985-09-04 AT AT0258985A patent/AT394723B/de not_active IP Right Cessation
- 1985-09-04 JP JP60195682A patent/JPS61112078A/ja active Granted
-
1986
- 1986-03-31 ES ES553548A patent/ES8706326A1/es not_active Expired
- 1986-03-31 ES ES553549A patent/ES8706327A1/es not_active Expired
-
1987
- 1987-11-12 GB GB08726516A patent/GB2196006B/en not_active Expired
-
1988
- 1988-07-15 CA CA000572256A patent/CA1254892A/fr not_active Expired
-
1990
- 1990-10-06 KR KR1019900015952A patent/KR900008840B1/ko not_active IP Right Cessation
- 1990-12-27 SE SE9004157A patent/SE9004157L/xx not_active Application Discontinuation
-
1991
- 1991-03-26 HK HK224/91A patent/HK22491A/xx unknown
- 1991-03-26 HK HK223/91A patent/HK22391A/xx unknown
-
1992
- 1992-04-03 CY CY1586A patent/CY1586A/xx unknown
- 1992-04-03 CY CY1585A patent/CY1585A/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: BRISTOL-MYERS CY Effective date: 19960930 |