ATE48421T1 - Hustenstillende und schleimregulierende 2substituierte thiazole. - Google Patents
Hustenstillende und schleimregulierende 2substituierte thiazole.Info
- Publication number
- ATE48421T1 ATE48421T1 AT85109445T AT85109445T ATE48421T1 AT E48421 T1 ATE48421 T1 AT E48421T1 AT 85109445 T AT85109445 T AT 85109445T AT 85109445 T AT85109445 T AT 85109445T AT E48421 T1 ATE48421 T1 AT E48421T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- group
- hydrogen
- murph
- regulator
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Photoreceptors In Electrophotography (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB08419254A GB2164333B (en) | 1984-07-27 | 1984-07-27 | Antitussive and mucus regulating 2-substituted thiazolidines |
| GB08517553A GB2177690A (en) | 1985-07-11 | 1985-07-11 | Antitussive and mucus regulating 2-substituted thiazolidines |
| EP85109445A EP0169581B1 (de) | 1984-07-27 | 1985-07-26 | Hustenstillende und schleimregulierende 2-substituierte Thiazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE48421T1 true ATE48421T1 (de) | 1989-12-15 |
Family
ID=26288033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85109445T ATE48421T1 (de) | 1984-07-27 | 1985-07-26 | Hustenstillende und schleimregulierende 2substituierte thiazole. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4857643A (de) |
| EP (1) | EP0169581B1 (de) |
| JP (1) | JPS6163669A (de) |
| AT (1) | ATE48421T1 (de) |
| AU (1) | AU582770B2 (de) |
| CA (1) | CA1270250A (de) |
| DE (1) | DE3574590D1 (de) |
| DK (1) | DK169474B1 (de) |
| ES (1) | ES8605249A1 (de) |
| GR (1) | GR851845B (de) |
| HU (1) | HU195492B (de) |
| IE (1) | IE58518B1 (de) |
| IL (1) | IL75891A (de) |
| NZ (1) | NZ212831A (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2177690A (en) * | 1985-07-11 | 1987-01-28 | Boehringer Biochemia Srl | Antitussive and mucus regulating 2-substituted thiazolidines |
| NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
| IT1196485B (it) * | 1986-07-14 | 1988-11-16 | Zambon Spa | Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica |
| IT1203932B (it) * | 1987-04-17 | 1989-02-23 | Boehringer Biochemia Srl | 2-sulfinil-acetil-1,3-tiazolidine, loro preparazione e composizioni farmaceutiche |
| IT1228251B (it) * | 1987-07-02 | 1991-06-05 | Boehringer Biochemia Srl | Amidi di amino-tioacetali ciclici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
| IT1223565B (it) * | 1987-12-21 | 1990-09-19 | Zambon Spa | Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica |
| IT1216119B (it) * | 1988-03-17 | 1990-02-22 | Boehringer Biochemia Srl | Beta_carbonil_carbossiamidi di 1,3_tiazolidine. |
| US5420289A (en) * | 1989-10-27 | 1995-05-30 | American Home Products Corporation | Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase |
| IT1270594B (it) * | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| JPWO2002051836A1 (ja) * | 2000-12-27 | 2004-04-22 | 協和醗酵工業株式会社 | ジペプチジルペプチダーゼ−ｉｖ阻害剤 |
| EP2070915A1 (de) * | 2007-12-03 | 2009-06-17 | A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. | Neues Verfahren zur Synthese von Moguistein |
| MX2012008530A (es) * | 2010-01-25 | 2013-02-21 | Kareus Therapeutics Sa | NUEVAS COMPOSICIONES PARA REDUCIR LA PRODUCCION DE Aß 42 Y SU USO PARA TRATAR LA ENFERMEDAD DE ALZHEIMER (AD). |
| CN102653527A (zh) * | 2011-12-22 | 2012-09-05 | 东莞达信生物技术有限公司 | 一种莫吉司坦合成工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR8266M (de) * | 1968-12-31 | 1970-10-26 | ||
| DE2926771A1 (de) * | 1979-07-03 | 1981-01-15 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
| IT1194793B (it) * | 1981-05-12 | 1988-09-28 | Corvi Camillo Spa | Derivati tiazolidinici ad attivita' farmacologica,procedimento per la loro preparazione e composizioni farmaceutiche contenenti detti derivati |
| US4649146A (en) * | 1983-01-31 | 1987-03-10 | Fujisawa Pharmaceutical Co., Ltd. | Thiazole derivatives and pharmaceutical composition comprising the same |
| DE3404786A1 (de) * | 1984-02-10 | 1985-08-14 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Neue alkanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltendes arzneimittel |
| US4732934A (en) * | 1986-12-08 | 1988-03-22 | General Electric Company | Functionalized thermoplastic polymers, blends prepared therefrom, and methods for preparing blends |
-
1985
- 1985-07-18 HU HU852765A patent/HU195492B/hu not_active IP Right Cessation
- 1985-07-22 NZ NZ212831A patent/NZ212831A/en unknown
- 1985-07-22 AU AU45242/85A patent/AU582770B2/en not_active Ceased
- 1985-07-23 IL IL75891A patent/IL75891A/xx not_active IP Right Cessation
- 1985-07-24 CA CA000487403A patent/CA1270250A/en not_active Expired - Lifetime
- 1985-07-25 GR GR851845A patent/GR851845B/el unknown
- 1985-07-26 ES ES545575A patent/ES8605249A1/es not_active Expired
- 1985-07-26 AT AT85109445T patent/ATE48421T1/de not_active IP Right Cessation
- 1985-07-26 IE IE187985A patent/IE58518B1/en not_active IP Right Cessation
- 1985-07-26 DK DK341985A patent/DK169474B1/da not_active IP Right Cessation
- 1985-07-26 JP JP60166620A patent/JPS6163669A/ja active Granted
- 1985-07-26 EP EP85109445A patent/EP0169581B1/de not_active Expired
- 1985-07-26 DE DE8585109445T patent/DE3574590D1/de not_active Expired - Lifetime
-
1988
- 1988-11-03 US US07/266,559 patent/US4857643A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0576944B2 (de) | 1993-10-25 |
| JPS6163669A (ja) | 1986-04-01 |
| DE3574590D1 (de) | 1990-01-11 |
| US4857643A (en) | 1989-08-15 |
| ES8605249A1 (es) | 1986-03-16 |
| NZ212831A (en) | 1988-05-30 |
| IL75891A (en) | 1989-07-31 |
| IE851879L (en) | 1986-01-27 |
| IE58518B1 (en) | 1993-10-06 |
| EP0169581A3 (en) | 1987-05-13 |
| EP0169581A2 (de) | 1986-01-29 |
| DK341985A (da) | 1986-01-28 |
| CA1270250A (en) | 1990-06-12 |
| EP0169581B1 (de) | 1989-12-06 |
| IL75891A0 (en) | 1985-12-31 |
| AU582770B2 (en) | 1989-04-13 |
| GR851845B (de) | 1985-12-02 |
| ES545575A0 (es) | 1986-03-16 |
| HUT38921A (en) | 1986-07-28 |
| DK341985D0 (da) | 1985-07-26 |
| HU195492B (en) | 1988-05-30 |
| DK169474B1 (da) | 1994-11-07 |
| AU4524285A (en) | 1986-01-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEFA | Change of the company name | ||
| REN | Ceased due to non-payment of the annual fee |