ATE61374T1 - Diaminoandrostanderivate. - Google Patents

Diaminoandrostanderivate.

Info

Publication number
ATE61374T1
ATE61374T1 AT86305079T AT86305079T ATE61374T1 AT E61374 T1 ATE61374 T1 AT E61374T1 AT 86305079 T AT86305079 T AT 86305079T AT 86305079 T AT86305079 T AT 86305079T AT E61374 T1 ATE61374 T1 AT E61374T1
Authority
AT
Austria
Prior art keywords
diaminoandrode
derivatives
chem
formula
group
Prior art date
Application number
AT86305079T
Other languages
English (en)
Inventor
Zoltan Tuba
Judit Horvath
Maria Lovas
Miklos Riesz
Laszlo Szporny
Egon Karpati
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Application granted granted Critical
Publication of ATE61374T1 publication Critical patent/ATE61374T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
AT86305079T 1985-07-01 1986-07-01 Diaminoandrostanderivate. ATE61374T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU852553A HU195972B (en) 1985-07-01 1985-07-01 Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them
EP86305079A EP0208497B1 (de) 1985-07-01 1986-07-01 Diaminoandrostanderivate

Publications (1)

Publication Number Publication Date
ATE61374T1 true ATE61374T1 (de) 1991-03-15

Family

ID=10959960

Family Applications (2)

Application Number Title Priority Date Filing Date
AT86305079T ATE61374T1 (de) 1985-07-01 1986-07-01 Diaminoandrostanderivate.
AT89108244T ATE90358T1 (de) 1985-07-01 1986-07-01 Zwischenprodukte in der synthese von diaminandrostan-derivaten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT89108244T ATE90358T1 (de) 1985-07-01 1986-07-01 Zwischenprodukte in der synthese von diaminandrostan-derivaten.

Country Status (9)

Country Link
US (1) US5410040A (de)
EP (2) EP0208497B1 (de)
JP (1) JPS625992A (de)
AT (2) ATE61374T1 (de)
AU (1) AU586691B2 (de)
CA (1) CA1314868C (de)
DE (2) DE3677841D1 (de)
HU (1) HU195972B (de)
IL (1) IL79211A0 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195972B (en) * 1985-07-01 1988-08-29 Richter Gedeon Vegyeszet Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them
US5708836A (en) 1990-11-13 1998-01-13 International Business Machines Corporation SIMD/MIMD inter-processor communication
US5590345A (en) 1990-11-13 1996-12-31 International Business Machines Corporation Advanced parallel array processor(APAP)
US5630162A (en) 1990-11-13 1997-05-13 International Business Machines Corporation Array processor dotted communication network based on H-DOTs
US5815723A (en) 1990-11-13 1998-09-29 International Business Machines Corporation Picket autonomy on a SIMD machine
US5794059A (en) 1990-11-13 1998-08-11 International Business Machines Corporation N-dimensional modified hypercube
US5617577A (en) 1990-11-13 1997-04-01 International Business Machines Corporation Advanced parallel array processor I/O connection
DE69131272T2 (de) 1990-11-13 1999-12-09 International Business Machines Corp., Armonk Paralleles Assoziativprozessor-System
US5625836A (en) 1990-11-13 1997-04-29 International Business Machines Corporation SIMD/MIMD processing memory element (PME)
US5765012A (en) 1990-11-13 1998-06-09 International Business Machines Corporation Controller for a SIMD/MIMD array having an instruction sequencer utilizing a canned routine library
US5765011A (en) 1990-11-13 1998-06-09 International Business Machines Corporation Parallel processing system having a synchronous SIMD processing with processing elements emulating SIMD operation using individual instruction streams
US5588152A (en) 1990-11-13 1996-12-24 International Business Machines Corporation Advanced parallel processor including advanced support hardware
US5963746A (en) 1990-11-13 1999-10-05 International Business Machines Corporation Fully distributed processing memory element
US5765015A (en) 1990-11-13 1998-06-09 International Business Machines Corporation Slide network for an array processor
US5734921A (en) 1990-11-13 1998-03-31 International Business Machines Corporation Advanced parallel array processor computer package
US5963745A (en) 1990-11-13 1999-10-05 International Business Machines Corporation APAP I/O programmable router
US5966528A (en) 1990-11-13 1999-10-12 International Business Machines Corporation SIMD/MIMD array processor with vector processing
US5828894A (en) 1990-11-13 1998-10-27 International Business Machines Corporation Array processor having grouping of SIMD pickets
US5809292A (en) 1990-11-13 1998-09-15 International Business Machines Corporation Floating point for simid array machine
US5594918A (en) 1991-05-13 1997-01-14 International Business Machines Corporation Parallel computer system providing multi-ported intelligent memory
JP2642039B2 (ja) 1992-05-22 1997-08-20 インターナショナル・ビジネス・マシーンズ・コーポレイション アレイ・プロセッサ
HU212459B (en) * 1992-10-02 1996-06-28 Richter Gedeon Vegyeszet Process for producing new 17-beta-substituted 4-aza-androstane-derivatives and pharmaceutical compositions containing them
HU210076B (en) * 1992-11-02 1995-01-30 Tuba Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura
EP2819574B1 (de) 2012-03-01 2019-01-02 Syracuse University Verbessertes elektronisches externes fötusüberwachungssystem
US20240352059A1 (en) * 2021-05-11 2024-10-24 Trustees Of Dartmouth College Liver x receptor modulators
CN116178475B (zh) * 2023-03-13 2025-07-29 奥锐特药业股份有限公司 一种醋酸阿比特龙及其中间体的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1042292A (en) * 1961-11-08 1966-09-14 Organon Labor Ltd 5ª‡-hydroxy-6ª‰-amino steroids and the preparation thereof
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
BE754360A (fr) * 1969-08-05 1971-02-03 Sandoz Sa Nouveaux derives de l'indole, leur preparation et medicaments contenantdes derives
HU168431B (de) * 1972-07-27 1976-04-28
DE2526788A1 (de) * 1975-06-13 1976-12-23 Schering Ag Verfahren zur herstellung von d-homo- steroiden
US4177190A (en) * 1975-08-01 1979-12-04 Richter Gedeon Vegyeszeti Gyar Rt. Diamino-androstanes and a process for the preparation of the said compounds
HU172521B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh triamino-androstana i chetvertichnykh solejj
HU172522B (hu) * 1975-08-01 1978-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 2beta, 16beta-diamino-androstana i ikh chetvertichnykh solej
HU195972B (en) * 1985-07-01 1988-08-29 Richter Gedeon Vegyeszet Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE3677841D1 (de) 1991-04-11
CA1314868C (en) 1993-03-23
US5410040A (en) 1995-04-25
IL79211A0 (en) 1986-09-30
DE3688559T2 (de) 1993-09-16
EP0345471A3 (en) 1990-02-07
EP0345471A2 (de) 1989-12-13
AU5936386A (en) 1987-01-08
EP0208497A3 (en) 1987-09-30
EP0208497B1 (de) 1991-03-06
HU195972B (en) 1988-08-29
ATE90358T1 (de) 1993-06-15
EP0208497A2 (de) 1987-01-14
JPS625992A (ja) 1987-01-12
DE3688559D1 (de) 1993-07-15
EP0345471B1 (de) 1993-06-09
AU586691B2 (en) 1989-07-20
HUT44041A (en) 1988-01-28

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