IT1216119B - Beta_carbonil_carbossiamidi di 1,3_tiazolidine. - Google Patents

Beta_carbonil_carbossiamidi di 1,3_tiazolidine.

Info

Publication number
IT1216119B
IT1216119B IT8819813A IT1981388A IT1216119B IT 1216119 B IT1216119 B IT 1216119B IT 8819813 A IT8819813 A IT 8819813A IT 1981388 A IT1981388 A IT 1981388A IT 1216119 B IT1216119 B IT 1216119B
Authority
IT
Italy
Prior art keywords
carbossiamidi
tiazolidine
carbonil
beta
alkyl
Prior art date
Application number
IT8819813A
Other languages
English (en)
Other versions
IT8819813A0 (it
Inventor
Carmelo A Gandolfi
Roberto Di Domenico
Silvano Spinelli
Licia Gallico
Bruno Lumachi
Sergio Tognella
Original Assignee
Boehringer Biochemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Srl filed Critical Boehringer Biochemia Srl
Publication of IT8819813A0 publication Critical patent/IT8819813A0/it
Priority to IT8819813A priority Critical patent/IT1216119B/it
Priority to US07/549,011 priority patent/US5206254A/en
Priority to PCT/EP1989/000205 priority patent/WO1989008648A1/en
Priority to KR1019890702146A priority patent/KR960011381B1/ko
Priority to HU891559A priority patent/HU205920B/hu
Priority to AU31892/89A priority patent/AU624124B2/en
Priority to RO145944A priority patent/RO107656B1/ro
Priority to JP1502573A priority patent/JPH0688987B2/ja
Priority to EP89902780A priority patent/EP0407403A1/en
Priority to EP89104349A priority patent/EP0333080B1/en
Priority to ES89104349T priority patent/ES2059595T3/es
Priority to AT89104349T priority patent/ATE95814T1/de
Priority to DE89104349T priority patent/DE68909815T2/de
Priority to ZA892014A priority patent/ZA892014B/xx
Priority to CA000593895A priority patent/CA1325632C/en
Application granted granted Critical
Publication of IT1216119B publication Critical patent/IT1216119B/it
Priority to FI904512A priority patent/FI95247C/fi
Priority to DK221490A priority patent/DK168486B1/da
Priority to BG92842A priority patent/BG60459B1/bg
Priority to SU90A priority patent/RU1833378C/ru
Priority to NO904031A priority patent/NO179370C/no
Priority to SG2094A priority patent/SG2094G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
IT8819813A 1988-03-17 1988-03-17 Beta_carbonil_carbossiamidi di 1,3_tiazolidine. IT1216119B (it)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IT8819813A IT1216119B (it) 1988-03-17 1988-03-17 Beta_carbonil_carbossiamidi di 1,3_tiazolidine.
US07/549,011 US5206254A (en) 1988-03-17 1989-03-02 β-carbonyl-carboxyamides of 1,3-thiazolidines
PCT/EP1989/000205 WO1989008648A1 (en) 1988-03-17 1989-03-02 beta-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES
KR1019890702146A KR960011381B1 (ko) 1988-03-17 1989-03-02 1, 3-티아졸라딘의 β-카르보닐-카르복시아미드
HU891559A HU205920B (en) 1988-03-17 1989-03-02 Process for producing 2-phenoxy-methyl/-3-/alkanoyl-, carboxy-, carbalkoxy- or carboxamido- -acetyl/-1,3-thiazolidine derivatives and pharmaceutical compositions containing them
AU31892/89A AU624124B2 (en) 1988-03-17 1989-03-02 Beta-carbonyl-carboxyamides of 1,3-thiazolidines
RO145944A RO107656B1 (ro) 1988-03-17 1989-03-02 Derivati de beta-carbonil-carboxiamide ale 1,3-tiazolidinelor si procedeu pentru prepararea acestora
JP1502573A JPH0688987B2 (ja) 1988-03-17 1989-03-02 １、３―チアゾリジンのβ―カルボニルカルボキシアミド
EP89902780A EP0407403A1 (en) 1988-03-17 1989-03-02 Beta-carbonyl-carboxyamides of 1,3-thiazolidines
DE89104349T DE68909815T2 (de) 1988-03-17 1989-03-11 Beta-carbonyl-carboxyamide von 1,3-Thiazolidinen.
EP89104349A EP0333080B1 (en) 1988-03-17 1989-03-11 Beta-carbonyl-carboxyamides of 1,3-thiazolidines
ES89104349T ES2059595T3 (es) 1988-03-17 1989-03-11 Beta-carbonil-carboxiamidas de 1,3-tiazolidinas.
AT89104349T ATE95814T1 (de) 1988-03-17 1989-03-11 Beta-carbonyl-carboxyamide von 1,3-thiazolidinen.
ZA892014A ZA892014B (en) 1988-03-17 1989-03-16 Beta-carbonyl-carboxyamides of 1,3-thiazolidines
CA000593895A CA1325632C (en) 1988-03-17 1989-03-16 .beta.-carbonyl-carboxyamides of 1,3-thiazolidines
FI904512A FI95247C (fi) 1988-03-17 1990-09-13 Menetelmä lääkeaineina käytettävien 1,3-tiatsolidinien -karbonyylikarboksiamidien valmistamiseksi
DK221490A DK168486B1 (da) 1988-03-17 1990-09-14 Beta-carbonyl-carboxyamider af 1,3-thiazolidiner, en fremgangsmåde til fremstilling deraf, et farmaceutisk præparat indeholdende en sådan thiazolidin, samt en anvendelse af en sådan thiazolidin til fremstilling af et lægemiddel med antihostevirkning
NO904031A NO179370C (no) 1988-03-17 1990-09-14 Analogifremgangsmåte ved fremstilling av terapeutisk aktive -karbonyl-karboksyamider av 1,3-tiazolidiner
SU90A RU1833378C (en) 1988-03-17 1990-09-14 Method of synthesis of thiazolidine derivatives
BG92842A BG60459B1 (bg) 1988-03-17 1990-09-14 МЕТОД ЗА ПОЛУЧАВАНЕ НА β-КАРБОНИЛ-КАРБОКСИАМИДИ НА 1,3-ТИАЗО- ЛИДИНИ
SG2094A SG2094G (en) 1988-03-17 1994-01-05 Beta-carbonyl-carboxyamides of 1,3-thiazolidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8819813A IT1216119B (it) 1988-03-17 1988-03-17 Beta_carbonil_carbossiamidi di 1,3_tiazolidine.

Publications (2)

Publication Number Publication Date
IT8819813A0 IT8819813A0 (it) 1988-03-17
IT1216119B true IT1216119B (it) 1990-02-22

Family

ID=11161493

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8819813A IT1216119B (it) 1988-03-17 1988-03-17 Beta_carbonil_carbossiamidi di 1,3_tiazolidine.

Country Status (19)

Country Link
US (1) US5206254A (it)
EP (2) EP0407403A1 (it)
JP (1) JPH0688987B2 (it)
KR (1) KR960011381B1 (it)
AT (1) ATE95814T1 (it)
AU (1) AU624124B2 (it)
BG (1) BG60459B1 (it)
CA (1) CA1325632C (it)
DE (1) DE68909815T2 (it)
DK (1) DK168486B1 (it)
ES (1) ES2059595T3 (it)
FI (1) FI95247C (it)
HU (1) HU205920B (it)
IT (1) IT1216119B (it)
NO (1) NO179370C (it)
RO (1) RO107656B1 (it)
RU (1) RU1833378C (it)
WO (1) WO1989008648A1 (it)
ZA (1) ZA892014B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245712B (it) * 1991-04-09 1994-10-14 Boehringer Mannheim Italia Ammine eterocicliche utili terapia dell'asma e dell'infiammazione delle vie aeree
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
US6083964A (en) * 1998-02-18 2000-07-04 K And K Biosciences, Inc. Optical resolution of racemic aminoalkylpyridine anticonvulsants and (+) aminoalkylpyridine enantiomers as highly potent orally effective anticonvulsant drugs and excitatory amino acid antagonists
WO2000030446A1 (en) 1998-11-23 2000-06-02 Bonnie Davis Dosage formulations for acetylcholinesterase inhibitors
CN1319955C (zh) * 2003-06-10 2007-06-06 浙江海正药业股份有限公司 莫吉斯坦晶型
WO2008144956A1 (fr) * 2007-05-28 2008-12-04 Tianjin Institute Of Pharmaceutical Research Nouveaux composés ambroxol, leurs procédés de préparation et leurs utilisations
EP2070915A1 (en) * 2007-12-03 2009-06-17 A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. New process for the synthesis of moguisteine
CN102653527A (zh) * 2011-12-22 2012-09-05 东莞达信生物技术有限公司 一种莫吉司坦合成工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195492B (en) * 1984-07-27 1988-05-30 Boehringer Biochemia Srl Process for producing 2-substituted thiazolidine derivatives with antitussive and mucus regulating action and pharmaceuticals comprising these compounds as active ingredient
GB2164333B (en) * 1984-07-27 1988-11-16 Boehringer Biochemia Srl Antitussive and mucus regulating 2-substituted thiazolidines
IT1201489B (it) * 1985-11-13 1989-02-02 Chiesi Farma Spa Derivati di tiazolidina,loro procedimento di preparazione e formulazioni farmaceutiche
IT1228251B (it) * 1987-07-02 1991-06-05 Boehringer Biochemia Srl Amidi di amino-tioacetali ciclici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
DK221490A (da) 1990-09-14
CA1325632C (en) 1993-12-28
ATE95814T1 (de) 1993-10-15
DK168486B1 (da) 1994-04-05
DK221490D0 (da) 1990-09-14
AU3189289A (en) 1989-10-05
ES2059595T3 (es) 1994-11-16
AU624124B2 (en) 1992-06-04
NO904031D0 (no) 1990-09-14
JPH03504123A (ja) 1991-09-12
IT8819813A0 (it) 1988-03-17
HU205920B (en) 1992-07-28
FI95247B (fi) 1995-09-29
DE68909815D1 (de) 1993-11-18
EP0333080A1 (en) 1989-09-20
FI904512A0 (fi) 1990-09-13
NO904031L (no) 1990-11-16
HU891559D0 (en) 1991-06-28
ZA892014B (en) 1989-11-29
RU1833378C (en) 1993-08-07
BG60459B1 (bg) 1995-04-28
EP0407403A1 (en) 1991-01-16
JPH0688987B2 (ja) 1994-11-09
NO179370B (no) 1996-06-17
NO179370C (no) 1996-09-25
EP0333080B1 (en) 1993-10-13
FI95247C (fi) 1996-01-10
US5206254A (en) 1993-04-27
DE68909815T2 (de) 1994-03-24
RO107656B1 (ro) 1993-12-30
KR960011381B1 (ko) 1996-08-22
WO1989008648A1 (en) 1989-09-21
HUT56355A (en) 1991-08-28
KR900700470A (ko) 1990-08-13

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950329