KR900700470A - 1, 3-티아졸라딘의 β-카르보닐-카르복시아미드 - Google Patents

1, 3-티아졸라딘의 β-카르보닐-카르복시아미드

Info

Publication number
KR900700470A
KR900700470A KR1019890702146A KR890702146A KR900700470A KR 900700470 A KR900700470 A KR 900700470A KR 1019890702146 A KR1019890702146 A KR 1019890702146A KR 890702146 A KR890702146 A KR 890702146A KR 900700470 A KR900700470 A KR 900700470A
Authority
KR
South Korea
Prior art keywords
thiazoladine
carboxyamide
carbonyl
alkyl
propargyl
Prior art date
Application number
KR1019890702146A
Other languages
English (en)
Other versions
KR960011381B1 (ko
Inventor
까멜로 에이. 간돌피
로베르토 디 도메니코
실바노 스피넬리
리키아 갈리코
브르노 루마키
세르기오 토그넬라
Original Assignee
베링거 만하임 이탈리아 에스. 피. 에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 베링거 만하임 이탈리아 에스. 피. 에이. filed Critical 베링거 만하임 이탈리아 에스. 피. 에이.
Publication of KR900700470A publication Critical patent/KR900700470A/ko
Application granted granted Critical
Publication of KR960011381B1 publication Critical patent/KR960011381B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
KR1019890702146A 1988-03-17 1989-03-02 1, 3-티아졸라딘의 β-카르보닐-카르복시아미드 KR960011381B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT19813A/88 1988-03-17
IT8819813A IT1216119B (it) 1988-03-17 1988-03-17 Beta_carbonil_carbossiamidi di 1,3_tiazolidine.
PCT/EP1989/000205 WO1989008648A1 (en) 1988-03-17 1989-03-02 beta-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES

Publications (2)

Publication Number Publication Date
KR900700470A true KR900700470A (ko) 1990-08-13
KR960011381B1 KR960011381B1 (ko) 1996-08-22

Family

ID=11161493

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890702146A KR960011381B1 (ko) 1988-03-17 1989-03-02 1, 3-티아졸라딘의 β-카르보닐-카르복시아미드

Country Status (19)

Country Link
US (1) US5206254A (ko)
EP (2) EP0407403A1 (ko)
JP (1) JPH0688987B2 (ko)
KR (1) KR960011381B1 (ko)
AT (1) ATE95814T1 (ko)
AU (1) AU624124B2 (ko)
BG (1) BG60459B1 (ko)
CA (1) CA1325632C (ko)
DE (1) DE68909815T2 (ko)
DK (1) DK168486B1 (ko)
ES (1) ES2059595T3 (ko)
FI (1) FI95247C (ko)
HU (1) HU205920B (ko)
IT (1) IT1216119B (ko)
NO (1) NO179370C (ko)
RO (1) RO107656B1 (ko)
RU (1) RU1833378C (ko)
WO (1) WO1989008648A1 (ko)
ZA (1) ZA892014B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245712B (it) * 1991-04-09 1994-10-14 Boehringer Mannheim Italia Ammine eterocicliche utili terapia dell'asma e dell'infiammazione delle vie aeree
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
US6083964A (en) * 1998-02-18 2000-07-04 K And K Biosciences, Inc. Optical resolution of racemic aminoalkylpyridine anticonvulsants and (+) aminoalkylpyridine enantiomers as highly potent orally effective anticonvulsant drugs and excitatory amino acid antagonists
WO2000030446A1 (en) 1998-11-23 2000-06-02 Bonnie Davis Dosage formulations for acetylcholinesterase inhibitors
CN1319955C (zh) * 2003-06-10 2007-06-06 浙江海正药业股份有限公司 莫吉斯坦晶型
WO2008144956A1 (fr) * 2007-05-28 2008-12-04 Tianjin Institute Of Pharmaceutical Research Nouveaux composés ambroxol, leurs procédés de préparation et leurs utilisations
EP2070915A1 (en) * 2007-12-03 2009-06-17 A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. New process for the synthesis of moguisteine
CN102653527A (zh) * 2011-12-22 2012-09-05 东莞达信生物技术有限公司 一种莫吉司坦合成工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195492B (en) * 1984-07-27 1988-05-30 Boehringer Biochemia Srl Process for producing 2-substituted thiazolidine derivatives with antitussive and mucus regulating action and pharmaceuticals comprising these compounds as active ingredient
GB2164333B (en) * 1984-07-27 1988-11-16 Boehringer Biochemia Srl Antitussive and mucus regulating 2-substituted thiazolidines
IT1201489B (it) * 1985-11-13 1989-02-02 Chiesi Farma Spa Derivati di tiazolidina,loro procedimento di preparazione e formulazioni farmaceutiche
IT1228251B (it) * 1987-07-02 1991-06-05 Boehringer Biochemia Srl Amidi di amino-tioacetali ciclici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
NO179370C (no) 1996-09-25
ES2059595T3 (es) 1994-11-16
IT1216119B (it) 1990-02-22
DK168486B1 (da) 1994-04-05
DK221490D0 (da) 1990-09-14
EP0407403A1 (en) 1991-01-16
KR960011381B1 (ko) 1996-08-22
DK221490A (da) 1990-09-14
EP0333080A1 (en) 1989-09-20
AU3189289A (en) 1989-10-05
HU205920B (en) 1992-07-28
RO107656B1 (ro) 1993-12-30
WO1989008648A1 (en) 1989-09-21
ATE95814T1 (de) 1993-10-15
AU624124B2 (en) 1992-06-04
JPH0688987B2 (ja) 1994-11-09
HU891559D0 (en) 1991-06-28
RU1833378C (en) 1993-08-07
FI95247B (fi) 1995-09-29
CA1325632C (en) 1993-12-28
NO904031D0 (no) 1990-09-14
IT8819813A0 (it) 1988-03-17
JPH03504123A (ja) 1991-09-12
FI904512A0 (fi) 1990-09-13
BG60459B1 (bg) 1995-04-28
ZA892014B (en) 1989-11-29
US5206254A (en) 1993-04-27
FI95247C (fi) 1996-01-10
DE68909815D1 (de) 1993-11-18
DE68909815T2 (de) 1994-03-24
EP0333080B1 (en) 1993-10-13
HUT56355A (en) 1991-08-28
NO904031L (no) 1990-11-16
NO179370B (no) 1996-06-17

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