DK168486B1 - Beta-carbonyl-carboxyamider af 1,3-thiazolidiner, en fremgangsmåde til fremstilling deraf, et farmaceutisk præparat indeholdende en sådan thiazolidin, samt en anvendelse af en sådan thiazolidin til fremstilling af et lægemiddel med antihostevirkning - Google Patents

Beta-carbonyl-carboxyamider af 1,3-thiazolidiner, en fremgangsmåde til fremstilling deraf, et farmaceutisk præparat indeholdende en sådan thiazolidin, samt en anvendelse af en sådan thiazolidin til fremstilling af et lægemiddel med antihostevirkning Download PDF

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Publication number
DK168486B1
DK168486B1 DK221490A DK221490A DK168486B1 DK 168486 B1 DK168486 B1 DK 168486B1 DK 221490 A DK221490 A DK 221490A DK 221490 A DK221490 A DK 221490A DK 168486 B1 DK168486 B1 DK 168486B1
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DK
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Prior art keywords
formula
thiazolidine
compound
compounds
methoxy
Prior art date
Application number
DK221490A
Other languages
Danish (da)
English (en)
Other versions
DK221490D0 (da
DK221490A (da
Inventor
Carmelo A Gandolfi
Roberto Di Domenico
Silvano Spinelli
Licia Gallico
Bruno Lumachi
Sergio Tognella
Original Assignee
Boehringer Mannheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Italia filed Critical Boehringer Mannheim Italia
Publication of DK221490D0 publication Critical patent/DK221490D0/da
Publication of DK221490A publication Critical patent/DK221490A/da
Application granted granted Critical
Publication of DK168486B1 publication Critical patent/DK168486B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Carbon And Carbon Compounds (AREA)
DK221490A 1988-03-17 1990-09-14 Beta-carbonyl-carboxyamider af 1,3-thiazolidiner, en fremgangsmåde til fremstilling deraf, et farmaceutisk præparat indeholdende en sådan thiazolidin, samt en anvendelse af en sådan thiazolidin til fremstilling af et lægemiddel med antihostevirkning DK168486B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT1981388 1988-03-17
IT8819813A IT1216119B (it) 1988-03-17 1988-03-17 Beta_carbonil_carbossiamidi di 1,3_tiazolidine.
EP8900205 1989-03-02
PCT/EP1989/000205 WO1989008648A1 (en) 1988-03-17 1989-03-02 beta-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES

Publications (3)

Publication Number Publication Date
DK221490D0 DK221490D0 (da) 1990-09-14
DK221490A DK221490A (da) 1990-09-14
DK168486B1 true DK168486B1 (da) 1994-04-05

Family

ID=11161493

Family Applications (1)

Application Number Title Priority Date Filing Date
DK221490A DK168486B1 (da) 1988-03-17 1990-09-14 Beta-carbonyl-carboxyamider af 1,3-thiazolidiner, en fremgangsmåde til fremstilling deraf, et farmaceutisk præparat indeholdende en sådan thiazolidin, samt en anvendelse af en sådan thiazolidin til fremstilling af et lægemiddel med antihostevirkning

Country Status (19)

Country Link
US (1) US5206254A (ko)
EP (2) EP0407403A1 (ko)
JP (1) JPH0688987B2 (ko)
KR (1) KR960011381B1 (ko)
AT (1) ATE95814T1 (ko)
AU (1) AU624124B2 (ko)
BG (1) BG60459B1 (ko)
CA (1) CA1325632C (ko)
DE (1) DE68909815T2 (ko)
DK (1) DK168486B1 (ko)
ES (1) ES2059595T3 (ko)
FI (1) FI95247C (ko)
HU (1) HU205920B (ko)
IT (1) IT1216119B (ko)
NO (1) NO179370C (ko)
RO (1) RO107656B1 (ko)
RU (1) RU1833378C (ko)
WO (1) WO1989008648A1 (ko)
ZA (1) ZA892014B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245712B (it) * 1991-04-09 1994-10-14 Boehringer Mannheim Italia Ammine eterocicliche utili terapia dell'asma e dell'infiammazione delle vie aeree
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
US6083964A (en) * 1998-02-18 2000-07-04 K And K Biosciences, Inc. Optical resolution of racemic aminoalkylpyridine anticonvulsants and (+) aminoalkylpyridine enantiomers as highly potent orally effective anticonvulsant drugs and excitatory amino acid antagonists
US7939522B1 (en) 1998-11-23 2011-05-10 Bonnie M Davis Dosage formulations for acetylcholinesterase inhibitors
CN1319955C (zh) * 2003-06-10 2007-06-06 浙江海正药业股份有限公司 莫吉斯坦晶型
WO2008144956A1 (fr) * 2007-05-28 2008-12-04 Tianjin Institute Of Pharmaceutical Research Nouveaux composés ambroxol, leurs procédés de préparation et leurs utilisations
EP2070915A1 (en) * 2007-12-03 2009-06-17 A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. New process for the synthesis of moguisteine
CN102653527A (zh) * 2011-12-22 2012-09-05 东莞达信生物技术有限公司 一种莫吉司坦合成工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2164333B (en) * 1984-07-27 1988-11-16 Boehringer Biochemia Srl Antitussive and mucus regulating 2-substituted thiazolidines
HU195492B (en) * 1984-07-27 1988-05-30 Boehringer Biochemia Srl Process for producing 2-substituted thiazolidine derivatives with antitussive and mucus regulating action and pharmaceuticals comprising these compounds as active ingredient
IT1201489B (it) * 1985-11-13 1989-02-02 Chiesi Farma Spa Derivati di tiazolidina,loro procedimento di preparazione e formulazioni farmaceutiche
IT1228251B (it) * 1987-07-02 1991-06-05 Boehringer Biochemia Srl Amidi di amino-tioacetali ciclici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
RU1833378C (en) 1993-08-07
FI95247B (fi) 1995-09-29
DE68909815D1 (de) 1993-11-18
DK221490D0 (da) 1990-09-14
RO107656B1 (ro) 1993-12-30
ZA892014B (en) 1989-11-29
JPH0688987B2 (ja) 1994-11-09
IT8819813A0 (it) 1988-03-17
NO904031L (no) 1990-11-16
IT1216119B (it) 1990-02-22
EP0407403A1 (en) 1991-01-16
WO1989008648A1 (en) 1989-09-21
AU3189289A (en) 1989-10-05
NO179370C (no) 1996-09-25
DK221490A (da) 1990-09-14
BG60459B1 (bg) 1995-04-28
AU624124B2 (en) 1992-06-04
HU205920B (en) 1992-07-28
ES2059595T3 (es) 1994-11-16
KR900700470A (ko) 1990-08-13
BG92842A (bg) 1993-12-24
ATE95814T1 (de) 1993-10-15
NO179370B (no) 1996-06-17
HU891559D0 (en) 1991-06-28
CA1325632C (en) 1993-12-28
EP0333080A1 (en) 1989-09-20
KR960011381B1 (ko) 1996-08-22
EP0333080B1 (en) 1993-10-13
FI95247C (fi) 1996-01-10
US5206254A (en) 1993-04-27
FI904512A0 (fi) 1990-09-13
NO904031D0 (no) 1990-09-14
JPH03504123A (ja) 1991-09-12
DE68909815T2 (de) 1994-03-24
HUT56355A (en) 1991-08-28

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