DE68909815T2 - Beta-carbonyl-carboxyamide von 1,3-Thiazolidinen. - Google Patents

Beta-carbonyl-carboxyamide von 1,3-Thiazolidinen.

Info

Publication number
DE68909815T2
DE68909815T2 DE89104349T DE68909815T DE68909815T2 DE 68909815 T2 DE68909815 T2 DE 68909815T2 DE 89104349 T DE89104349 T DE 89104349T DE 68909815 T DE68909815 T DE 68909815T DE 68909815 T2 DE68909815 T2 DE 68909815T2
Authority
DE
Germany
Prior art keywords
carboxyamides
thiazolidines
carbonyl
beta
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE89104349T
Other languages
English (en)
Other versions
DE68909815D1 (de
Inventor
Carmelo A Gandolfi
Domenico Roberto Di
Silvano Spinelli
Bruno Lumachi
Licia Gallico
Sergio Tognella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dompe International SA
Original Assignee
Roche Diagnostics SpA
Boehringer Mannheim Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics SpA, Boehringer Mannheim Italia SpA filed Critical Roche Diagnostics SpA
Publication of DE68909815D1 publication Critical patent/DE68909815D1/de
Application granted granted Critical
Publication of DE68909815T2 publication Critical patent/DE68909815T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE89104349T 1988-03-17 1989-03-11 Beta-carbonyl-carboxyamide von 1,3-Thiazolidinen. Expired - Lifetime DE68909815T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8819813A IT1216119B (it) 1988-03-17 1988-03-17 Beta_carbonil_carbossiamidi di 1,3_tiazolidine.

Publications (2)

Publication Number Publication Date
DE68909815D1 DE68909815D1 (de) 1993-11-18
DE68909815T2 true DE68909815T2 (de) 1994-03-24

Family

ID=11161493

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89104349T Expired - Lifetime DE68909815T2 (de) 1988-03-17 1989-03-11 Beta-carbonyl-carboxyamide von 1,3-Thiazolidinen.

Country Status (19)

Country Link
US (1) US5206254A (de)
EP (2) EP0407403A1 (de)
JP (1) JPH0688987B2 (de)
KR (1) KR960011381B1 (de)
AT (1) ATE95814T1 (de)
AU (1) AU624124B2 (de)
BG (1) BG60459B1 (de)
CA (1) CA1325632C (de)
DE (1) DE68909815T2 (de)
DK (1) DK168486B1 (de)
ES (1) ES2059595T3 (de)
FI (1) FI95247C (de)
HU (1) HU205920B (de)
IT (1) IT1216119B (de)
NO (1) NO179370C (de)
RO (1) RO107656B1 (de)
RU (1) RU1833378C (de)
WO (1) WO1989008648A1 (de)
ZA (1) ZA892014B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1245712B (it) * 1991-04-09 1994-10-14 Boehringer Mannheim Italia Ammine eterocicliche utili terapia dell'asma e dell'infiammazione delle vie aeree
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
US6083964A (en) * 1998-02-18 2000-07-04 K And K Biosciences, Inc. Optical resolution of racemic aminoalkylpyridine anticonvulsants and (+) aminoalkylpyridine enantiomers as highly potent orally effective anticonvulsant drugs and excitatory amino acid antagonists
EP1133230A4 (de) 1998-11-23 2004-05-26 Bonnie M Davis Dosisformulierungen für acetylcholinesterase-inhibitoren
CN1319955C (zh) * 2003-06-10 2007-06-06 浙江海正药业股份有限公司 莫吉斯坦晶型
WO2008144956A1 (fr) * 2007-05-28 2008-12-04 Tianjin Institute Of Pharmaceutical Research Nouveaux composés ambroxol, leurs procédés de préparation et leurs utilisations
EP2070915A1 (de) * 2007-12-03 2009-06-17 A.M.S.A. ANONIMA MATERIE SINTETICHE E AFFINI S.p.A. Neues Verfahren zur Synthese von Moguistein
CN102653527A (zh) * 2011-12-22 2012-09-05 东莞达信生物技术有限公司 一种莫吉司坦合成工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU195492B (en) * 1984-07-27 1988-05-30 Boehringer Biochemia Srl Process for producing 2-substituted thiazolidine derivatives with antitussive and mucus regulating action and pharmaceuticals comprising these compounds as active ingredient
GB2164333B (en) * 1984-07-27 1988-11-16 Boehringer Biochemia Srl Antitussive and mucus regulating 2-substituted thiazolidines
IT1201489B (it) * 1985-11-13 1989-02-02 Chiesi Farma Spa Derivati di tiazolidina,loro procedimento di preparazione e formulazioni farmaceutiche
IT1228251B (it) * 1987-07-02 1991-06-05 Boehringer Biochemia Srl Amidi di amino-tioacetali ciclici, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
ES2059595T3 (es) 1994-11-16
ATE95814T1 (de) 1993-10-15
BG60459B1 (bg) 1995-04-28
AU624124B2 (en) 1992-06-04
WO1989008648A1 (en) 1989-09-21
ZA892014B (en) 1989-11-29
HU891559D0 (en) 1991-06-28
US5206254A (en) 1993-04-27
FI95247C (fi) 1996-01-10
DE68909815D1 (de) 1993-11-18
AU3189289A (en) 1989-10-05
EP0407403A1 (de) 1991-01-16
JPH0688987B2 (ja) 1994-11-09
JPH03504123A (ja) 1991-09-12
HU205920B (en) 1992-07-28
DK221490D0 (da) 1990-09-14
EP0333080A1 (de) 1989-09-20
EP0333080B1 (de) 1993-10-13
CA1325632C (en) 1993-12-28
NO904031D0 (no) 1990-09-14
NO179370B (no) 1996-06-17
HUT56355A (en) 1991-08-28
RO107656B1 (ro) 1993-12-30
DK168486B1 (da) 1994-04-05
FI95247B (fi) 1995-09-29
KR900700470A (ko) 1990-08-13
DK221490A (da) 1990-09-14
NO179370C (no) 1996-09-25
IT1216119B (it) 1990-02-22
FI904512A0 (fi) 1990-09-13
NO904031L (no) 1990-11-16
KR960011381B1 (ko) 1996-08-22
RU1833378C (en) 1993-08-07
IT8819813A0 (it) 1988-03-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: F. HOFFMANN-LA ROCHE AG, BASEL, CH

8328 Change in the person/name/address of the agent

Free format text: VOSSIUS & PARTNER, 81675 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: DOMPE INTERNATIONAL S.A., LAUSANNE, CH