CA2931684C - Human mesothelin chimeric antigen receptors and uses thereof - Google Patents

Human mesothelin chimeric antigen receptors and uses thereof Download PDF

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Publication number
CA2931684C
CA2931684C CA2931684A CA2931684A CA2931684C CA 2931684 C CA2931684 C CA 2931684C CA 2931684 A CA2931684 A CA 2931684A CA 2931684 A CA2931684 A CA 2931684A CA 2931684 C CA2931684 C CA 2931684C
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Prior art keywords
seq
acid sequence
amino acid
cell
mesothelin
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CA2931684A
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French (fr)
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CA2931684A1 (en
Inventor
Gregory Beatty
Boris ENGELS
Neeraja Idamakanti
Carl H. June
Andreas Loew
Huijuan SONG
Qilong WU
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Novartis AG
University of Pennsylvania Penn
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Novartis AG
University of Pennsylvania Penn
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Priority to CA3225453A priority Critical patent/CA3225453A1/en
Priority to CA3225456A priority patent/CA3225456A1/en
Publication of CA2931684A1 publication Critical patent/CA2931684A1/en
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    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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CA2931684A 2013-12-19 2014-12-19 Human mesothelin chimeric antigen receptors and uses thereof Active CA2931684C (en)

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CA3225453A CA3225453A1 (en) 2013-12-19 2014-12-19 Human mesothelin chimeric antigen receptors and uses thereof
CA3225456A CA3225456A1 (en) 2013-12-19 2014-12-19 Human mesothelin chimeric antigen receptors and uses thereof

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Application Number Priority Date Filing Date Title
CN2013089979 2013-12-19
CNPCT/CN2013/089979 2013-12-19
CNPCT/CN2014/082610 2014-07-21
CN2014082610 2014-07-21
CN2014090509 2014-11-06
CNPCT/CN2014/090509 2014-11-06
PCT/CN2014/094393 WO2015090230A1 (en) 2013-12-19 2014-12-19 Human mesothelin chimeric antigen receptors and uses thereof

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