BR112019008560A2 - célula artificial que apresenta antígeno, método para expandir linfócitos infiltrantes de tumor, para tratar um câncer com uma população de linfócitos infiltrantes de tumor e para avaliar a potência de linfócitos infiltrantes de tumor, kit, população de linfócitos infiltrantes de tumor, e, combinação - Google Patents

célula artificial que apresenta antígeno, método para expandir linfócitos infiltrantes de tumor, para tratar um câncer com uma população de linfócitos infiltrantes de tumor e para avaliar a potência de linfócitos infiltrantes de tumor, kit, população de linfócitos infiltrantes de tumor, e, combinação

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Publication number
BR112019008560A2
BR112019008560A2 BR112019008560-2A BR112019008560A BR112019008560A2 BR 112019008560 A2 BR112019008560 A2 BR 112019008560A2 BR 112019008560 A BR112019008560 A BR 112019008560A BR 112019008560 A2 BR112019008560 A2 BR 112019008560A2
Authority
BR
Brazil
Prior art keywords
tumor infiltrating
infiltrating lymphocytes
population
aapcs
assessing
Prior art date
Application number
BR112019008560-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Veerapathran Anand
Gokuldass Aishwarya
Rabinovich Brian
T. Lotze Michael
Original Assignee
Iovance Biotherapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iovance Biotherapeutics, Inc. filed Critical Iovance Biotherapeutics, Inc.
Publication of BR112019008560A2 publication Critical patent/BR112019008560A2/pt

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    • C12N5/0635—B lymphocytes
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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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BR112019008560-2A 2016-10-31 2017-10-31 célula artificial que apresenta antígeno, método para expandir linfócitos infiltrantes de tumor, para tratar um câncer com uma população de linfócitos infiltrantes de tumor e para avaliar a potência de linfócitos infiltrantes de tumor, kit, população de linfócitos infiltrantes de tumor, e, combinação BR112019008560A2 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662415274P 2016-10-31 2016-10-31
US62/415274 2016-10-31
US201662438600P 2016-12-23 2016-12-23
US62/438600 2016-12-23
US201762475053P 2017-03-22 2017-03-22
US62/475053 2017-03-22
US201762481831P 2017-04-05 2017-04-05
US62/481831 2017-04-05
PCT/US2017/059271 WO2018081789A1 (en) 2016-10-31 2017-10-31 Engineered artificial antigen presenting cells for tumor infiltrating lymphocyte expansion

Publications (1)

Publication Number Publication Date
BR112019008560A2 true BR112019008560A2 (pt) 2019-09-17

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BR112019008560-2A BR112019008560A2 (pt) 2016-10-31 2017-10-31 célula artificial que apresenta antígeno, método para expandir linfócitos infiltrantes de tumor, para tratar um câncer com uma população de linfócitos infiltrantes de tumor e para avaliar a potência de linfócitos infiltrantes de tumor, kit, população de linfócitos infiltrantes de tumor, e, combinação

Country Status (14)

Country Link
US (4) US10415015B2 (https=)
EP (1) EP3532608A1 (https=)
JP (2) JP7576912B2 (https=)
KR (2) KR20190071802A (https=)
CN (2) CN110312790A (https=)
AU (2) AU2017347942A1 (https=)
BR (1) BR112019008560A2 (https=)
CA (1) CA3041673A1 (https=)
IL (1) IL266221B2 (https=)
MA (1) MA46668A (https=)
MX (2) MX2019004708A (https=)
SG (1) SG11201903825SA (https=)
TW (1) TWI788307B (https=)
WO (1) WO2018081789A1 (https=)

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GB201522097D0 (en) 2015-12-15 2016-01-27 Cellular Therapeutics Ltd Cells
MX2019004707A (es) 2016-10-26 2019-08-12 Iovance Biotherapeutics Inc Reestimulacion de linfocitos infiltrantes de tumor crioconservados.
TWI788307B (zh) * 2016-10-31 2023-01-01 美商艾歐凡斯生物治療公司 用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
JOP20190224A1 (ar) 2017-03-29 2019-09-26 Iovance Biotherapeutics Inc عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي
US11254913B1 (en) 2017-03-29 2022-02-22 Iovance Biotherapeutics, Inc. Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
US20200377855A1 (en) * 2017-05-05 2020-12-03 H. Lee Moffitt Cancer Center And Research Institute, Inc. Rapid method for the culture of tumor infiltrating lymphocytes
EP3635097A1 (en) 2017-06-05 2020-04-15 Iovance Biotherapeutics, Inc. Methods of using tumor infiltrating lymphocytes in double-refractory melanoma
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