BR112016010551A2 - variantes de alfa-amilases tendo suscetibilidade reduzida à clivagem da protease e métodos de uso das mesmas - Google Patents

variantes de alfa-amilases tendo suscetibilidade reduzida à clivagem da protease e métodos de uso das mesmas

Info

Publication number
BR112016010551A2
BR112016010551A2 BR112016010551A BR112016010551A BR112016010551A2 BR 112016010551 A2 BR112016010551 A2 BR 112016010551A2 BR 112016010551 A BR112016010551 A BR 112016010551A BR 112016010551 A BR112016010551 A BR 112016010551A BR 112016010551 A2 BR112016010551 A2 BR 112016010551A2
Authority
BR
Brazil
Prior art keywords
alpha
methods
amylase variants
protease cleavage
reduced susceptibility
Prior art date
Application number
BR112016010551A
Other languages
English (en)
Inventor
Finan Dina
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of BR112016010551A2 publication Critical patent/BR112016010551A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01001—Alpha-amylase (3.2.1.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

a presente invenção refere-se a composições e métodos relacionados a enzimas variantes de alfa-amilase compreendendo mutações que reduzem sua suscetibilidade à digestão proteolítica e me-lhoram seu desempenho. as variantes de alfa-amilases são particularmente úteis em aplicações que exigem que alfa-amilases e protea-ses estejam presentes na mesma solução.
BR112016010551A 2013-11-20 2014-11-13 variantes de alfa-amilases tendo suscetibilidade reduzida à clivagem da protease e métodos de uso das mesmas BR112016010551A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361906617P 2013-11-20 2013-11-20
PCT/US2014/065522 WO2015077126A1 (en) 2013-11-20 2014-11-13 Variant alpha-amylases having reduced susceptibility to protease cleavage, and methods of use, thereof

Publications (1)

Publication Number Publication Date
BR112016010551A2 true BR112016010551A2 (pt) 2017-12-05

Family

ID=52023630

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016010551A BR112016010551A2 (pt) 2013-11-20 2014-11-13 variantes de alfa-amilases tendo suscetibilidade reduzida à clivagem da protease e métodos de uso das mesmas

Country Status (7)

Country Link
US (1) US20160272957A1 (pt)
EP (1) EP3071691B1 (pt)
JP (1) JP6560214B2 (pt)
CN (1) CN105960456A (pt)
BR (1) BR112016010551A2 (pt)
MX (1) MX2016006489A (pt)
WO (1) WO2015077126A1 (pt)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3354728B1 (en) * 2012-12-21 2020-04-22 Danisco US Inc. Alpha-amylase variants
CN107250365A (zh) * 2015-02-19 2017-10-13 丹尼斯科美国公司 增强的蛋白质表达
EP3872174B1 (en) 2015-05-13 2023-03-01 Danisco US Inc. Aprl-clade protease variants and uses thereof
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
DK3307427T3 (da) 2015-06-09 2023-11-06 Danisco Us Inc Osmotisk sprængnings-kapsler
JP7015695B2 (ja) 2015-06-17 2022-02-03 ダニスコ・ユーエス・インク バチルス・ギブソニイ（Ｂａｃｉｌｌｕｓ ｇｉｂｓｏｎｉｉ）クレードセリンプロテアーゼ
US20180320158A1 (en) 2015-11-05 2018-11-08 Danisco Us Inc. Paenibacillus and bacillus spp. mannanases
EP4141113A1 (en) 2015-11-05 2023-03-01 Danisco US Inc Paenibacillus sp. mannanases
CN108779448B (zh) * 2015-12-09 2023-08-18 丹尼斯科美国公司 α-淀粉酶组合变体
US20180362946A1 (en) 2015-12-18 2018-12-20 Danisco Us Inc. Polypeptides with endoglucanase activity and uses thereof
DE102016201643A1 (de) * 2016-02-03 2017-08-03 Henkel Ag & Co. Kgaa Verbesserte Waschleistung durch eine alpha-Amylase aus Bacillus cereus
CA3022875A1 (en) 2016-05-03 2017-11-09 Danisco Us Inc Protease variants and uses thereof
EP3845642B1 (en) 2016-05-05 2023-08-09 Danisco US Inc. Protease variants and uses thereof
EP3455352A1 (en) 2016-05-09 2019-03-20 Novozymes A/S Variant polypeptides with improved performance and use of the same
JP2019523645A (ja) 2016-05-31 2019-08-29 ダニスコ・ユーエス・インク プロテアーゼ変異体およびその使用
JP7152319B2 (ja) 2016-06-17 2022-10-12 ダニスコ・ユーエス・インク プロテアーゼ変異体およびその使用
WO2018085524A2 (en) 2016-11-07 2018-05-11 Danisco Us Inc Laundry detergent composition
CN110312794B (zh) 2016-12-21 2024-04-12 丹尼斯科美国公司 吉氏芽孢杆菌进化枝丝氨酸蛋白酶
CN110312795A (zh) 2016-12-21 2019-10-08 丹尼斯科美国公司 蛋白酶变体及其用途
EP3583210B1 (en) 2017-03-15 2021-07-07 Danisco US Inc. Trypsin-like serine proteases and uses thereof
WO2018184004A1 (en) 2017-03-31 2018-10-04 Danisco Us Inc Alpha-amylase combinatorial variants
US20200040283A1 (en) 2017-03-31 2020-02-06 Danisco Us Inc Delayed release enzyme formulations for bleach-containing detergents
JP2020527339A (ja) 2017-06-30 2020-09-10 ダニスコ・ユーエス・インク 低凝集の酵素含有粒子
CN111212906B (zh) 2017-08-18 2024-02-02 丹尼斯科美国公司 α-淀粉酶变体
CN107653283B (zh) * 2017-10-31 2021-02-09 新疆浙大阳光生物科技有限公司 一种黄霉素的制备方法
CN111373039A (zh) 2017-11-29 2020-07-03 丹尼斯科美国公司 具有改善的稳定性的枯草杆菌蛋白酶变体
US20210222148A1 (en) 2017-12-21 2021-07-22 Danisco Us Inc. Enzyme-containing, hot-melt granules comprising a thermotolerant desiccant
BR112020016068A2 (pt) 2018-02-08 2020-12-08 Danisco Us Inc. Partículas cera termicamente resistente matriz para encapsulamento de enzima
US20210363470A1 (en) 2018-06-19 2021-11-25 Danisco Us Inc Subtilisin variants
US20210214703A1 (en) 2018-06-19 2021-07-15 Danisco Us Inc Subtilisin variants
US20230174962A1 (en) 2018-07-31 2023-06-08 Danisco Us Inc Variant alpha-amylases having amino acid substitutions that lower the pka of the general acid
EP3844255A1 (en) 2018-08-30 2021-07-07 Danisco US Inc. Enzyme-containing granules
US20220033737A1 (en) 2018-09-27 2022-02-03 Danisco Us Inc Compositions for medical instrument cleaning
CN113166745A (zh) 2018-10-12 2021-07-23 丹尼斯科美国公司 在螯合剂存在下具有可增强稳定性的突变的α-淀粉酶
WO2020112599A1 (en) 2018-11-28 2020-06-04 Danisco Us Inc Subtilisin variants having improved stability
WO2020242858A1 (en) 2019-05-24 2020-12-03 Danisco Us Inc Subtilisin variants and methods of use
CN114174486A (zh) 2019-06-06 2022-03-11 丹尼斯科美国公司 用于清洁的方法和组合物
US10941432B1 (en) * 2019-08-15 2021-03-09 Santiago De Urbina Gaviria Method for the preparation of low molecular weight porcine lympho-reticular polypeptides
WO2021080948A2 (en) 2019-10-24 2021-04-29 Danisco Us Inc Variant maltopentaose/maltohexaose-forming alpha-amylases
EP4204553A1 (en) 2020-08-27 2023-07-05 Danisco US Inc. Enzymes and enzyme compositions for cleaning
EP4203698A1 (en) 2020-08-28 2023-07-05 Kerry Luxembourg S.a.r.l. Feed composition supplemented with a protease combination comprising neutral metalloprotease and serine alkaline protease at a given ratio
CN116997642A (zh) 2021-01-29 2023-11-03 丹尼斯科美国公司 清洁组合物及其相关的方法
WO2023278297A1 (en) 2021-06-30 2023-01-05 Danisco Us Inc Variant lipases and uses thereof
WO2023034486A2 (en) 2021-09-03 2023-03-09 Danisco Us Inc. Laundry compositions for cleaning
WO2023039270A2 (en) 2021-09-13 2023-03-16 Danisco Us Inc. Bioactive-containing granules
CA3241094A1 (en) 2021-12-16 2023-06-22 Jonathan LASSILA Variant maltopentaose/maltohexaose-forming alpha-amylases
WO2023114932A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023114936A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023114939A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
JP2023095355A (ja) * 2021-12-24 2023-07-06 花王株式会社 アミラーゼ配合洗浄剤組成物
WO2023168234A1 (en) 2022-03-01 2023-09-07 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
WO2023250301A1 (en) 2022-06-21 2023-12-28 Danisco Us Inc. Methods and compositions for cleaning comprising a polypeptide having thermolysin activity
WO2024050343A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Subtilisin variants and methods related thereto
WO2024050346A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Detergent compositions and methods related thereto
WO2024050339A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Mannanase variants and methods of use
WO2024102698A1 (en) 2022-11-09 2024-05-16 Danisco Us Inc. Subtilisin variants and methods of use

Family Cites Families (190)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB1483591A (en) 1973-07-23 1977-08-24 Novo Industri As Process for coating water soluble or water dispersible particles by means of the fluid bed technique
DE2413561A1 (de) 1974-03-21 1975-10-02 Henkel & Cie Gmbh Lagerbestaendiger, leichtloeslicher waschmittelzusatz und verfahren zu dessen herstellung
US3929678A (en) 1974-08-01 1975-12-30 Procter & Gamble Detergent composition having enhanced particulate soil removal performance
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
JPS5534046A (en) 1978-09-01 1980-03-10 Cpc International Inc Novel glucoamyrase having excellent heat resistance and production
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
NO840200L (no) 1983-01-28 1984-07-30 Cefus Corp Glukoamylase cdna.
US4536477A (en) 1983-08-17 1985-08-20 Cpc International Inc. Thermostable glucoamylase and method for its production
US5422267A (en) 1984-05-22 1995-06-06 Robert R. Yocum Industrial yeast comprising an integrated glucoamylase gene
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
US4587215A (en) 1984-06-25 1986-05-06 Uop Inc. Highly thermostable amyloglucosidase
DE3428834A1 (de) 1984-08-04 1986-02-13 Henkel KGaA, 4000 Düsseldorf Geschirreinigungsmittel
US4628031A (en) 1984-09-18 1986-12-09 Michigan Biotechnology Institute Thermostable starch converting enzymes
GB8514707D0 (en) 1985-06-11 1985-07-10 Unilever Plc Enzymatic detergent composition
GB8514708D0 (en) 1985-06-11 1985-07-10 Unilever Plc Enzymatic detergent composition
DK154572C (da) 1985-08-07 1989-04-24 Novo Industri As Enzymatisk detergentadditiv, detergent og fremgangsmaade til vask af tekstiler
EP0218272B1 (en) 1985-08-09 1992-03-18 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
EG18543A (en) 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
DE3764460D1 (de) 1986-05-21 1990-09-27 Novo Industri As Herstellung eines ein enzym enthaltenden granulates und dessen verwendung in reinigungsmitteln.
DE3750450T2 (de) 1986-08-29 1995-01-05 Novo Industri As Enzymhaltiger Reinigungsmittelzusatz.
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
GB8629536D0 (en) 1986-12-10 1987-01-21 Unilever Plc Enzymatic detergent composition
GB8629534D0 (en) 1986-12-10 1987-01-21 Unilever Plc Enzymatic detergent & bleaching composition
ATE125865T1 (de) 1987-08-28 1995-08-15 Novo Nordisk As Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen.
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体ｄｎａ、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
DE68911131T2 (de) 1988-03-24 1994-03-31 Novonordisk As Cellulosezubereitung.
US5648263A (en) 1988-03-24 1997-07-15 Novo Nordisk A/S Methods for reducing the harshness of a cotton-containing fabric
GB8811045D0 (en) 1988-05-10 1988-06-15 Unilever Plc Enzymatic detergent composition
GB8813687D0 (en) 1988-06-09 1988-07-13 Unilever Plc Enzymatic dishwashing & rinsing composition
DK78089D0 (da) 1989-02-20 1989-02-20 Novo Industri As Detergentholdigt granulat og fremgangsmaade til fremstilling deraf
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
US5156773A (en) 1989-12-12 1992-10-20 Novo Nordisk A/S Stabilized enzymatic liquid detergent composition
ES2051122T3 (es) 1990-03-01 1994-06-01 Novo Nordisk As Quitamanchas liquido que contiene lipasa y uso de dicho quitamanchas.
US5447649A (en) 1990-03-01 1995-09-05 Novo Nordisk A/S Lipase containing liquid pre-spotter and use of such pre-spotter
JP3112937B2 (ja) 1990-04-14 2000-11-27 カリ―ヒエミー アクチエンゲゼルシヤフト アルカリ性バチルスーリパーゼ、これをコード化するｄｎａ配列およびこのリパーゼを生産するバチルス
WO1991017243A1 (en) 1990-05-09 1991-11-14 Novo Nordisk A/S A cellulase preparation comprising an endoglucanase enzyme
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
US5162210A (en) 1990-06-29 1992-11-10 Iowa State University Research Foundation Process for enzymatic hydrolysis of starch to glucose
DE69129988T2 (de) 1990-09-13 1999-03-18 Novo Nordisk As Lipase-varianten
AU663851B2 (en) 1990-09-28 1995-10-26 Procter & Gamble Company, The Polyhydroxy fatty acid amide surfactants to enhance enzyme performance
CA2097180C (en) 1990-12-10 2007-08-14 Timothy Fowler Saccharification of cellulose by cloning and amplification of the .beta.-glucosidase gene of trichoderma reesei
ES2174820T3 (es) 1991-01-16 2002-11-16 Procter & Gamble Composiciones detergentes compactas con celulasa de alta actividad.
EP0511456A1 (en) 1991-04-30 1992-11-04 The Procter & Gamble Company Liquid detergents with aromatic borate ester to inhibit proteolytic enzyme
DE69209500T2 (de) 1991-04-30 1996-10-31 Procter & Gamble Gerüstsubstanzhaltige flüssigwaschmittel mit borsäure-polyolkomplex zur ptoteolytischen enzyminhibierung
DE69226182T2 (de) 1991-05-01 1999-01-21 Novo Nordisk As Stabilisierte enzyme und waschmittelzusammensetzungen
DK72992D0 (da) 1992-06-01 1992-06-01 Novo Nordisk As Enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
DE4232170C2 (de) 1992-09-25 1999-09-16 Henkel Kgaa Schwachalkalische Geschirreinigungsmittel
US5898025A (en) 1992-09-25 1999-04-27 Henkel Kommanditgesellschaft Auf Aktien Mildly alkaline dishwashing detergents
WO1994007998A1 (en) 1992-10-06 1994-04-14 Novo Nordisk A/S Cellulase variants
US5281526A (en) 1992-10-20 1994-01-25 Solvay Enzymes, Inc. Method of purification of amylase by precipitation with a metal halide and 4-hydroxybenzic acid or a derivative thereof
US5763383A (en) 1992-12-22 1998-06-09 Novo Nordisk A/S Alkaline lipases
KR950702240A (ko) 1993-04-27 1995-06-19 한스 발터 라벤 세제로의 이용을 위한 새로운 리파제 변형체
DK52393D0 (pt) 1993-05-05 1993-05-05 Novo Nordisk As
CA2162021A1 (en) 1993-05-05 1994-11-10 POUL NõRGAARD CHRISTENSEN Cleaning gel
DK76893D0 (pt) 1993-06-28 1993-06-28 Novo Nordisk As
DE4322229A1 (de) 1993-07-05 1995-01-12 Cognis Bio Umwelt Umhüllte Enzymzubereitung für Wasch- und Reinigungsmittel
CA2166683A1 (en) 1993-07-09 1995-01-19 Lone Kierstein Nielsen Boronic acid or borinic acid derivatives as enzyme stabilizers
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
AU7853194A (en) 1993-10-13 1995-05-04 Novo Nordisk A/S H2o2-stable peroxidase variants
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
DE4344215A1 (de) 1993-12-23 1995-06-29 Cognis Bio Umwelt Silberkorrosionsschutzmittelhaltige Enzymzubereitung
AU1806795A (en) 1994-02-22 1995-09-04 Novo Nordisk A/S A method of preparing a variant of a lipolytic enzyme
DE4405511A1 (de) 1994-02-22 1995-08-24 Henkel Kgaa Waschmittel mit amorphen silikatischen Buildersubstanzen
US5691295A (en) 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
ATE512226T1 (de) 1994-02-24 2011-06-15 Henkel Ag & Co Kgaa Verbesserte enzyme und detergentien damit
ES2251717T3 (es) 1994-03-08 2006-05-01 Novozymes A/S Nuevas celulasas alcalinas.
CA2189441C (en) 1994-05-04 2009-06-30 Wolfgang Aehle Lipases with improved surfactant resistance
WO1995035381A1 (en) 1994-06-20 1995-12-28 Unilever N.V. Modified pseudomonas lipases and their use
WO1996000292A1 (en) 1994-06-23 1996-01-04 Unilever N.V. Modified pseudomonas lipases and their use
DE4422433A1 (de) 1994-06-28 1996-01-04 Cognis Bio Umwelt Mehrenzymgranulat
AU3604595A (en) 1994-10-06 1996-05-02 Novo Nordisk A/S An enzyme and enzyme preparation with endoglucanase activity
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
JPH10507639A (ja) 1994-10-26 1998-07-28 ノボ ノルディスク アクティーゼルスカブ 酵素界面活性剤組成物
CN1167503A (zh) 1994-10-26 1997-12-10 诺沃挪第克公司 一种具有脂解活性的酶
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
CN1182451A (zh) 1995-03-17 1998-05-20 诺沃挪第克公司 新的内切葡聚糖酶
JP3895377B2 (ja) 1995-06-13 2007-03-22 ノボザイムス アクティーゼルスカブ 酵素安定剤としての４−置換フェニルボロン酸
US6071356A (en) 1995-07-12 2000-06-06 Novo Nordisk Als Cleaning-in-place with a solution containing a protease and a lipase
JP4307549B2 (ja) 1995-07-14 2009-08-05 ノボザイムス アクティーゼルスカブ 脂肪分解活性を有する修飾された酵素
EP0839224A1 (en) 1995-07-19 1998-05-06 Novo Nordisk A/S Treatment of fabrics
ES2221934T3 (es) 1995-08-11 2005-01-16 Novozymes A/S Nuevas enzimas lipoliticas.
DE19615776A1 (de) 1996-04-20 1997-10-23 Henkel Kgaa Löslichkeitsverbessertes Enzymgranulat
US5763385A (en) * 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
WO1998008940A1 (en) 1996-08-26 1998-03-05 Novo Nordisk A/S A novel endoglucanase
CN100362100C (zh) 1996-09-17 2008-01-16 诺沃奇梅兹有限公司 纤维素酶变体
AU730286B2 (en) 1996-10-08 2001-03-01 Novo Nordisk A/S Diaminobenzoic acid derivatives as dye precursors
US6300116B1 (en) 1996-11-04 2001-10-09 Novozymes A/S Modified protease having improved autoproteolytic stability
EP0948610B1 (en) 1996-11-04 2011-05-25 Novozymes A/S Subtilase variants and compositions
DE19703364A1 (de) 1997-01-30 1998-08-06 Henkel Ecolab Gmbh & Co Ohg Pastenförmiges Wasch- und Reinigungsmittel
US6159731A (en) 1997-02-12 2000-12-12 Massachusetts Institute Of Technology Daxx, a Fas-binding protein that activates JNK and apoptosis
US6060441A (en) 1997-04-10 2000-05-09 Henkel Corporation Cleaning compositions having enhanced enzyme activity
DE19717329A1 (de) 1997-04-24 1998-10-29 Henkel Ecolab Gmbh & Co Ohg Flüssige Enzymzubereitung und ihre Verwendung
WO1999028448A1 (en) 1997-11-26 1999-06-10 Novo Nordisk A/S Thermostable glucoamylase
AU2207099A (en) 1997-12-24 1999-07-19 Genencor International, Inc. An improved method of assaying for a preferred enzyme and/or preferred detergentcomposition
AU3247699A (en) 1998-02-17 1999-09-06 Novo Nordisk A/S Lipase variant
WO2000004136A1 (en) 1998-07-15 2000-01-27 Novozymes A/S Glucoamylase variants
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
DE19904512A1 (de) 1999-02-04 2000-08-17 Henkel Ecolab Gmbh & Co Ohg Verfahren zur Reinigung von Mehrwegflaschen
DE19914811A1 (de) 1999-03-31 2000-10-05 Henkel Kgaa Enzym- und bleichaktivatorhaltige Wasch- und Reinigungsmittel
AU3420100A (en) 1999-03-31 2000-10-23 Novozymes A/S Lipase variant
US6964944B1 (en) 1999-06-02 2005-11-15 Novozymes A/S Chemically modified lipolytic enzyme
US6254645B1 (en) 1999-08-20 2001-07-03 Genencor International, Inc. Enzymatic modification of the surface of a polyester fiber or article
US6933140B1 (en) 1999-11-05 2005-08-23 Genencor International, Inc. Enzymes useful for changing the properties of polyester
KR20030037267A (ko) 2000-07-28 2003-05-12 헨켈 코만디트게젤샤프트 아우프 악티엔 바실러스속 ａ ７－７ (ｄｓｍ １２３６８) 에서 추출한신규한 아밀분해 효소 및 상기 신규한 아밀분해 효소를함유하는 세척 및 세정제
US8658585B2 (en) 2000-11-27 2014-02-25 Tanguy Marie Louise Alexandre Catlin Detergent products, methods and manufacture
ES2329725T3 (es) 2000-11-27 2009-11-30 THE PROCTER & GAMBLE COMPANY Productos detergentes, metodos y fabricacion.
PL361363A1 (en) 2000-11-28 2004-10-04 Henkel Kommanditgesellschaft Auf Aktien Novel cyclodextrin glucanotransferase (cgtase), obtained from bacillus agaradherens (dsm 9948) and detergents and cleaning agents containing said novel cyclodextrin glucanotransferase
DE10121463A1 (de) 2001-05-02 2003-02-27 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
DE10138753B4 (de) 2001-08-07 2017-07-20 Henkel Ag & Co. Kgaa Wasch- und Reinigungsmittel mit Hybrid-Alpha-Amylasen
DE10142124A1 (de) 2001-08-30 2003-03-27 Henkel Kgaa Umhüllte Wirkstoffzubereitung für den Einsatz in teilchenförmigen Wasch- und Reinigungsmitteln
DE10153792A1 (de) 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
DE10163884A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10237200A1 (de) 2002-08-14 2004-03-04 Henkel Kgaa Portionierte Wasch- oder Reinigungsmittelzusammensetzung
JP4851093B2 (ja) 2002-12-11 2012-01-11 ノボザイムス アクティーゼルスカブ 洗剤組成物
WO2004074419A2 (en) 2003-02-18 2004-09-02 Novozymes A/S Detergent compositions
DE10361084A1 (de) 2003-06-13 2005-01-05 Henkel Kgaa Lagerstabile Bleichmittelzusammensetzungen auf Basis von Peroxycarbonsäuren
DE10361081A1 (de) 2003-06-13 2005-01-05 Henkel Kgaa Verfahren zur Stabilisierung von Peroxycarbonsäuren in tensidhaltigen Dispersionen
US8703459B2 (en) 2003-12-05 2014-04-22 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Catalytic domains of beta(1,4)-galactosyltransferase I having altered metal ion specificity
DE10360805A1 (de) 2003-12-23 2005-07-28 Henkel Kgaa Neue Alkalische Protease und Wasch- und Reinigungsmittel, enthaltend diese neue Alkalische Protease
DE102004019751A1 (de) 2004-04-23 2005-11-17 Henkel Kgaa Neue Alkalische Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Alkalischen Proteasen
DE102004048590A1 (de) 2004-04-27 2005-11-24 Henkel Kgaa Reinigungsmittel mit Klarspül-Sulfopolymer und einer speziellen α-Amylase
DE102004048591A1 (de) 2004-04-27 2005-11-24 Henkel Kgaa Reinigungsmittel mit Klarspültensid und einer speziellen α-Amylase
DE102004025859A1 (de) 2004-05-24 2005-12-22 Henkel Kgaa Kit aus Schwamm und Reiniger
US7413887B2 (en) 2004-05-27 2008-08-19 Genecor International, Inc. Trichoderma reesei glucoamylase and homologs thereof
DE102004040849A1 (de) 2004-08-23 2006-03-02 Henkel Kgaa Klares Wasch- und Reinigungsmittel mit Fließgrenze
WO2006032277A1 (en) 2004-09-21 2006-03-30 Novozymes A/S Subtilases
DE102004047097A1 (de) 2004-09-29 2006-04-06 Henkel Kgaa Wasch- und Reinigungsmittel mit immobilisierten aktiven Inhaltsstoffen
DE102004047777B4 (de) 2004-10-01 2018-05-09 Basf Se Alpha-Amylase-Varianten mit erhöhter Lösungsmittelstabilität, Verfahren zu deren Herstellung sowie deren Verwendung
EP1661978B1 (en) 2004-11-29 2011-03-02 The Procter & Gamble Company Detergent compositions
EP1726636B2 (en) 2005-03-03 2016-11-23 The Procter & Gamble Company Detergent Compositions
EP1698689A1 (en) 2005-03-03 2006-09-06 The Procter & Gamble Company Detergent compositions
DE102005015328A1 (de) 2005-04-01 2006-10-05 Henkel Kgaa Klares Wasch- und Reinigungsmittel mit Fließgrenze
GB0522659D0 (en) 2005-11-07 2005-12-14 Reckitt Benckiser Nv Delivery cartridge
WO2007134614A1 (de) 2006-05-18 2007-11-29 Henkel Ag & Co. Kgaa Farbschützendes waschmittel
EP1867707B1 (en) 2006-06-16 2011-09-07 The Procter & Gamble Company Detergent compositions
EP2041253A4 (en) 2006-07-03 2012-06-06 Novozymes Biologicals Inc CLEANING COMPOSITION
DE602006020852D1 (de) 2006-07-07 2011-05-05 Procter & Gamble Waschmittelzusammensetzungen
DE602006020853D1 (de) 2006-07-07 2011-05-05 Procter & Gamble Waschmittelzusammensetzungen
US7968691B2 (en) 2006-08-23 2011-06-28 Danisco Us Inc. Pullulanase variants with increased productivity
DE102006039873B4 (de) 2006-08-25 2013-10-31 Henkel Ag & Co. Kgaa Verstärkung der Reinigungsleistung von Waschmitteln durch baumwollaktives schmutzablösevermögendes Cellulosederivat
DE102007006629A1 (de) 2007-02-06 2008-08-07 Henkel Ag & Co. Kgaa Reinigungsmittel
ES2554983T3 (es) 2007-04-03 2015-12-28 Henkel Ag & Co. Kgaa Agente de lavado inhibidor del agrisado
KR20090128448A (ko) 2007-04-03 2009-12-15 헨켈 아게 운트 코. 카게아아 발오 성분을 함유하는 세제
KR20100024395A (ko) * 2007-05-30 2010-03-05 다니스코 유에스 인크. 바실러스 리케니포르미스 알파-아밀라아제의 개선된 변이체
FR2918671B1 (fr) 2007-07-10 2010-10-15 Sanofi Pasteur Milieu de culture d'haemophilus influenzae type b.
DE102007033104A1 (de) 2007-07-13 2009-01-15 Henkel Ag & Co. Kgaa Mittel enthaltend Proteasen aus Stenotrophomonas maltophilia
CA2704494A1 (en) * 2007-11-02 2009-05-14 The Scripps Research Institute Directed evolution using proteins comprising unnatural amino acids
WO2009061379A2 (en) * 2007-11-05 2009-05-14 Danisco Us Inc., Genencor Division Alpha-amylase variants with altered properties
CA2704791A1 (en) 2007-11-05 2009-05-14 Danisco Us Inc. Variants of bacillus sp. ts-23 alpha-amylase with altered properties
NZ584366A (en) * 2007-11-05 2012-03-30 Danisco Us Inc Variants of bacillus licheniformis alpha-amylase with increased thermostability and/or decreased calcium dependence
DK2222842T3 (en) 2007-11-20 2015-01-19 Danisco Us Inc Glucoamylasevarianter with changed properties
US8066818B2 (en) 2008-02-08 2011-11-29 The Procter & Gamble Company Water-soluble pouch
WO2009118329A1 (en) 2008-03-28 2009-10-01 Novozymes A/S Triggered release system
US8691743B2 (en) 2008-05-14 2014-04-08 Novozymes A/S Liquid detergent compositions
GB0810881D0 (en) 2008-06-16 2008-07-23 Unilever Plc Improvements relating to fabric cleaning
DE102008038479A1 (de) 2008-08-20 2010-02-25 Henkel Ag & Co. Kgaa Wasch- oder Reinigungsmittel mit gesteigerter Waschkraft
CN102239264B (zh) 2008-10-03 2013-11-20 纳幕尔杜邦公司 含羧酸酯制剂中过水解酶的稳定
US20100125046A1 (en) 2008-11-20 2010-05-20 Denome Frank William Cleaning products
EP2367923A2 (en) 2008-12-01 2011-09-28 Danisco US Inc. Enzymes with lipase activity
WO2010066631A1 (en) 2008-12-12 2010-06-17 Henkel Ag & Co. Kgaa Laundry article having cleaning and conditioning properties
DE102008061859A1 (de) 2008-12-15 2010-06-17 Henkel Ag & Co. Kgaa Maschinelles Geschirrspülmittel
DE102009001186A1 (de) 2009-02-26 2010-09-02 Henkel Ag & Co. Kgaa Handgeschirrspülmittel
DE102009001688A1 (de) 2009-03-20 2010-09-23 Henkel Ag & Co. Kgaa Aldehyd-haltiges Wasch-, Reinigungs-, Nachbehandlungs-oder Waschhilfsmittel mit antibakterieller Wirkung
CN102378813B (zh) 2009-04-01 2014-05-14 丹尼斯科美国公司 包含具有改变的性质的α-淀粉酶变体的组合物和方法
GB0911428D0 (en) 2009-07-02 2009-08-12 Reckitt Benckiser Nv Composition
DE102009046217A1 (de) 2009-10-30 2011-05-12 Henkel Ag & Co. Kgaa Flüssiges maschinelles Geschirrspülmittel
DK2510094T3 (en) 2009-12-09 2017-03-13 Danisco Us Inc COMPOSITIONS AND METHODS OF COMPREHENSIVE PROTEASE VARIETIES
MX2012006616A (es) 2009-12-09 2012-06-21 Procter & Gamble Productos para el cuidado de las telas y el hogar.
EP2343310A1 (en) 2010-01-08 2011-07-13 Novozymes A/S Serine hydrolase formulation
EP2357220A1 (en) 2010-02-10 2011-08-17 The Procter & Gamble Company Cleaning composition comprising amylase variants with high stability in the presence of a chelating agent
US9896673B2 (en) 2010-02-10 2018-02-20 Novozymes A/S Compositions of high stability alpha amylase variants
EP2377914B1 (en) 2010-04-19 2016-11-09 The Procter & Gamble Company Mildly alkaline, low-built, solid fabric treatment detergent composition comprising perhydrolase
US20110240510A1 (en) 2010-04-06 2011-10-06 Johan Maurice Theo De Poortere Optimized release of bleaching systems in laundry detergents
US20120067373A1 (en) 2010-04-15 2012-03-22 Philip Frank Souter Automatic Dishwashing Detergent Composition
AR080886A1 (es) 2010-04-15 2012-05-16 Danisco Us Inc Composiciones y metodos que comprenden proteasas variantes
WO2011131585A1 (en) 2010-04-20 2011-10-27 Henkel Ag & Co. Kgaa Laundry article having cleaning properties
PL2566960T3 (pl) 2010-05-06 2017-08-31 The Procter And Gamble Company Produkty konsumenckie z odmianami proteaz
BR112012031362A2 (pt) 2010-06-03 2015-10-13 Mascoma Corp levedura expressando enzimas sacarolíticas para bioprocessamento consolidado usando amido e celulose
EP2395070A1 (en) 2010-06-10 2011-12-14 The Procter & Gamble Company Liquid laundry detergent composition comprising lipase of bacterial origin
EP2395071A1 (en) 2010-06-10 2011-12-14 The Procter & Gamble Company Solid detergent composition comprising lipase of bacterial origin
WO2012145062A1 (en) 2011-02-16 2012-10-26 The Procter & Gamble Company Liquid cleaning compositions
EP2697352A1 (en) 2011-04-12 2014-02-19 The Procter and Gamble Company Metal bleach catalysts
DE102012201522A1 (de) * 2012-02-02 2013-08-08 Basf Se Lagerstabiles flüssiges Geschirrspülmittel enthaltend Protease und Amylase
EP3354728B1 (en) * 2012-12-21 2020-04-22 Danisco US Inc. Alpha-amylase variants

Also Published As

Publication number Publication date
US20160272957A1 (en) 2016-09-22
EP3071691B1 (en) 2019-10-23
MX2016006489A (es) 2016-08-03
JP6560214B2 (ja) 2019-08-14
CN105960456A (zh) 2016-09-21
JP2016538860A (ja) 2016-12-15
WO2015077126A1 (en) 2015-05-28
EP3071691A1 (en) 2016-09-28

Similar Documents

Publication Publication Date Title
BR112016010551A2 (pt) variantes de alfa-amilases tendo suscetibilidade reduzida à clivagem da protease e métodos de uso das mesmas
BR112015004467A2 (pt) método para controlar a heterogeneidade de proteínas
MX2021000416A (es) Substratos de metaloproteinasas de matriz y otras porciones escindibles y metodos para usar los mismos.
AR087745A1 (es) Composiciones y metodos que comprenden una variante de enzima lipolitica
BR112014018677A8 (pt) Detergente líquido, uso de um detergente, método de limpeza de superfícies duras e uso de uma protease
BR112014000874A2 (pt) composições detergentes
GT201400099A (es) Proteínas que pueden unirse a la il-1
EA201500172A1 (ru) Модифицированные полипептиды фактора х и их применение
UY33331A (es) Proteinas de dominio de armazon basadas en fibronectina que se unen a pcsk9
BR112015020795A2 (pt) derivados de pirazol novos
BR112019000046A2 (pt) alfa-amilases para combinação com glucoamilases para aumentar a sacarificação
BR112014027283A2 (pt) variantes de enzima aprimoradas
BR112015003591A8 (pt) Usos de lys-c e métodos para fabricação de um polipeptídeo proteoliticamente processado
BR112014031627A2 (pt) superfícies nanotexturizadas antineblina e artigos contendo os mesmos
AR092879A1 (es) Proteinas de fusion de g3p como agentes de union a amiloide
EA201792608A3 (ru) Применение белков p3 бактериофага в качестве агентов, связывающих амилоид
DK3433360T3 (da) Proteaser med forbedret enzymstabilitet i vaskemidler
BR112014016803A2 (pt) amidas macrocíclicas como inibidoras de protease
BR112015027824A2 (pt) composições de vitamina e em pó
BR112013024562A2 (pt) fios de fibra de vidro e produtos reforçados compreendendo os mesmos
BR112016013800A2 (pt) Composições e métodos para reduzir alérgenos de gatos no ambiente
PE20151206A1 (es) Polipeptidos del factor vii de accion corta
BR112014021326A2 (pt) célula para a expressão de protéina, método para reduzir a atividade de amidação de peptídeo em uma determinada célula, uso de uma célula
BR112017015180A2 (pt) métodos para controlar a produção de proteases
BR112014019220A8 (pt) Novos derivados de pirrolidina

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements