BG106168A - Индолилпиперидинови производни като антихистаминови и антиалергични средства - Google Patents

Индолилпиперидинови производни като антихистаминови и антиалергични средства Download PDF

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Publication number
BG106168A
BG106168A BG106168A BG10616801A BG106168A BG 106168 A BG106168 A BG 106168A BG 106168 A BG106168 A BG 106168A BG 10616801 A BG10616801 A BG 10616801A BG 106168 A BG106168 A BG 106168A
Authority
BG
Bulgaria
Prior art keywords
ethoxy
piperidin
indol
ethyl
benzoic acid
Prior art date
Application number
BG106168A
Other languages
Bulgarian (bg)
English (en)
Inventor
Santacana Lluis Pages
Pou Silvia Fonquerna
Duran Carles Puig
Forner Dolors Fernandez
Original Assignee
Almirall Prodesfarma, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma, S.A. filed Critical Almirall Prodesfarma, S.A.
Publication of BG106168A publication Critical patent/BG106168A/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG106168A 1999-06-04 2001-12-03 Индолилпиперидинови производни като антихистаминови и антиалергични средства BG106168A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009901232A ES2165274B1 (es) 1999-06-04 1999-06-04 Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
PCT/EP2000/005010 WO2000075130A1 (en) 1999-06-04 2000-05-31 Indolylpiperidine derivatives as antihistaminic and antiallergic agents

Publications (1)

Publication Number Publication Date
BG106168A true BG106168A (bg) 2002-07-31

Family

ID=8308707

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106168A BG106168A (bg) 1999-06-04 2001-12-03 Индолилпиперидинови производни като антихистаминови и антиалергични средства

Country Status (35)

Country Link
US (1) US6683096B2 (ko)
EP (1) EP1183251B1 (ko)
JP (1) JP2003501424A (ko)
KR (1) KR100683454B1 (ko)
CN (1) CN1191246C (ko)
AR (1) AR029640A1 (ko)
AT (1) ATE259362T1 (ko)
AU (1) AU773164B2 (ko)
BG (1) BG106168A (ko)
BR (1) BR0011340A (ko)
CA (1) CA2375985A1 (ko)
CO (1) CO5180556A1 (ko)
CZ (1) CZ20014334A3 (ko)
DE (1) DE60008239T2 (ko)
DK (1) DK1183251T3 (ko)
EE (1) EE04717B1 (ko)
ES (2) ES2165274B1 (ko)
HK (1) HK1040990A1 (ko)
HU (1) HUP0203320A3 (ko)
IL (1) IL146629A0 (ko)
MX (1) MXPA01012425A (ko)
MY (1) MY127033A (ko)
NO (1) NO20015897D0 (ko)
NZ (1) NZ515649A (ko)
PE (1) PE20010208A1 (ko)
PL (1) PL196774B1 (ko)
PT (1) PT1183251E (ko)
RU (1) RU2246493C2 (ko)
SI (1) SI1183251T1 (ko)
SK (1) SK17042001A3 (ko)
TR (1) TR200103490T2 (ko)
TW (1) TWI226889B (ko)
UA (1) UA72517C2 (ko)
WO (1) WO2000075130A1 (ko)
ZA (1) ZA200109676B (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004504266A (ja) * 2000-01-17 2004-02-12 バイエル　アクチェンゲゼルシャフト 置換アリールケトン類
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
AU2002243394A1 (en) * 2000-11-16 2002-06-24 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
ES2201907B1 (es) 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
AU2004291297B2 (en) 2003-11-17 2011-06-23 Boehringer Ingelheim International Gmbh Novel piperidine-substituted indoles- or heteroderivatives thereof
US20050245540A1 (en) * 2003-12-09 2005-11-03 Fujisawa Pharmaceutical Co., Ltd. New methods
GEP20094680B (en) 2004-04-13 2009-05-10 Incyte Corp Piperazinylpiperidine derivatives as chemokine receptor antagonists
US20060009491A1 (en) * 2004-06-24 2006-01-12 Incyte Corporation Amido compounds and their use as pharmaceuticals
EP1758580A4 (en) 2004-06-24 2008-01-16 Incyte Corp N-SUBSTITUTED PIPERIDINE AND ITS USE AS A MEDICAMENT
DE602006013115D1 (de) * 2005-04-26 2010-05-06 Hypnion Inc Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
WO2006117314A2 (en) 2005-04-30 2006-11-09 Boehringer Ingelheim International Gmbh Novel piperidin- substituted indoles and their use as ccr-3 modulators
US20060275516A1 (en) * 2005-06-02 2006-12-07 Ram A N S Compositions and methods for the treatment of allergic rhinitis
US20080108586A1 (en) * 2006-09-06 2008-05-08 Incyte Corporation Combination therapy for human immunodeficiency virus infection
CA2667547C (en) * 2006-10-27 2014-07-29 Boehringer Ingelheim International Gmbh Piperidyl-propane-thiol ccr3 modulators
AU2008225766B2 (en) 2007-03-15 2012-06-07 Novartis Ag Organic compounds and their uses
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
CN101560179B (zh) * 2009-05-25 2012-04-18 浙江大学 具有h3受体亲和能力的含氮吲哚衍生物和用途
CN101747321B (zh) * 2009-12-22 2013-01-02 浙江大学 吲哚-3-苄胺衍生物及制备方法和用途
EP3040334A1 (en) * 2014-12-29 2016-07-06 Faes Farma, S.A. New benzimidazole derivatives as antihistamine agents
IL310330A (en) * 2021-07-30 2024-03-01 Confo Therapeutics N V Compounds for the treatment of pain, in particular neuropathic pain, and/or other diseases or disorders associated with AT2R and/or AT2R-mediated signaling

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
JPS63301881A (ja) * 1987-06-01 1988-12-08 Fujisawa Pharmaceut Co Ltd インドリルピペリジン誘導体
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8900382D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
AU669156B2 (en) * 1992-02-13 1996-05-30 Merrell Dow Pharmaceuticals Inc. Piperidinyl thiacyclic derivatives
IT1271417B (it) * 1993-10-15 1997-05-28 Erregierre Ind Chim Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono.
DE19500689A1 (de) 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
DE19707628A1 (de) 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
AR028685A1 (es) * 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol

Also Published As

Publication number Publication date
DE60008239D1 (de) 2004-03-18
CN1368969A (zh) 2002-09-11
AU773164B2 (en) 2004-05-20
RU2246493C2 (ru) 2005-02-20
DE60008239T2 (de) 2004-11-18
DK1183251T3 (da) 2004-06-07
KR20020020721A (ko) 2002-03-15
PT1183251E (pt) 2004-05-31
SI1183251T1 (en) 2004-06-30
KR100683454B1 (ko) 2007-02-20
ATE259362T1 (de) 2004-02-15
EP1183251B1 (en) 2004-02-11
AR029640A1 (es) 2003-07-10
CA2375985A1 (en) 2000-12-14
TR200103490T2 (tr) 2002-04-22
SK17042001A3 (sk) 2002-04-04
UA72517C2 (uk) 2005-03-15
ES2165274B1 (es) 2003-04-01
ES2211559T3 (es) 2004-07-16
US6683096B2 (en) 2004-01-27
AU5527600A (en) 2000-12-28
CZ20014334A3 (cs) 2002-03-13
BR0011340A (pt) 2002-03-05
HUP0203320A3 (en) 2004-01-28
EE200100653A (et) 2003-02-17
EE04717B1 (et) 2006-10-16
NO20015897L (no) 2001-12-03
US20020147344A1 (en) 2002-10-10
RU2002100073A (ru) 2004-01-10
NZ515649A (en) 2003-08-29
TWI226889B (en) 2005-01-21
JP2003501424A (ja) 2003-01-14
NO20015897D0 (no) 2001-12-03
EP1183251A1 (en) 2002-03-06
HUP0203320A2 (hu) 2003-02-28
PL353164A1 (en) 2003-10-20
ZA200109676B (en) 2003-02-24
HK1040990A1 (zh) 2002-06-28
PL196774B1 (pl) 2008-01-31
CN1191246C (zh) 2005-03-02
PE20010208A1 (es) 2001-03-19
MXPA01012425A (es) 2002-06-04
CO5180556A1 (es) 2002-07-30
WO2000075130A1 (en) 2000-12-14
MY127033A (en) 2006-11-30
ES2165274A1 (es) 2002-03-01
IL146629A0 (en) 2002-07-25

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