EE200100653A - Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine - Google Patents

Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine

Info

Publication number
EE200100653A
EE200100653A EEP200100653A EEP200100653A EE200100653A EE 200100653 A EE200100653 A EE 200100653A EE P200100653 A EEP200100653 A EE P200100653A EE P200100653 A EEP200100653 A EE P200100653A EE 200100653 A EE200100653 A EE 200100653A
Authority
EE
Estonia
Prior art keywords
preparation
composition
indolylpiperidine compounds
indolylpiperidine
compounds
Prior art date
Application number
EEP200100653A
Other languages
English (en)
Inventor
Pages Santacana Lluis
Fonquerna Pou Silvia
Puig Duran Carles
Fernandez Forner Dolors
Original Assignee
Almirall Prodesfarma, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma, S.A. filed Critical Almirall Prodesfarma, S.A.
Publication of EE200100653A publication Critical patent/EE200100653A/et
Publication of EE04717B1 publication Critical patent/EE04717B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200100653A 1999-06-04 2000-05-31 Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine EE04717B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009901232A ES2165274B1 (es) 1999-06-04 1999-06-04 Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
PCT/EP2000/005010 WO2000075130A1 (en) 1999-06-04 2000-05-31 Indolylpiperidine derivatives as antihistaminic and antiallergic agents

Publications (2)

Publication Number Publication Date
EE200100653A true EE200100653A (et) 2003-02-17
EE04717B1 EE04717B1 (et) 2006-10-16

Family

ID=8308707

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100653A EE04717B1 (et) 1999-06-04 2000-05-31 Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine

Country Status (35)

Country Link
US (1) US6683096B2 (et)
EP (1) EP1183251B1 (et)
JP (1) JP2003501424A (et)
KR (1) KR100683454B1 (et)
CN (1) CN1191246C (et)
AR (1) AR029640A1 (et)
AT (1) ATE259362T1 (et)
AU (1) AU773164B2 (et)
BG (1) BG106168A (et)
BR (1) BR0011340A (et)
CA (1) CA2375985A1 (et)
CO (1) CO5180556A1 (et)
CZ (1) CZ20014334A3 (et)
DE (1) DE60008239T2 (et)
DK (1) DK1183251T3 (et)
EE (1) EE04717B1 (et)
ES (2) ES2165274B1 (et)
HK (1) HK1040990A1 (et)
HU (1) HUP0203320A3 (et)
IL (1) IL146629A0 (et)
MX (1) MXPA01012425A (et)
MY (1) MY127033A (et)
NO (1) NO20015897L (et)
NZ (1) NZ515649A (et)
PE (1) PE20010208A1 (et)
PL (1) PL196774B1 (et)
PT (1) PT1183251E (et)
RU (1) RU2246493C2 (et)
SI (1) SI1183251T1 (et)
SK (1) SK17042001A3 (et)
TR (1) TR200103490T2 (et)
TW (1) TWI226889B (et)
UA (1) UA72517C2 (et)
WO (1) WO2000075130A1 (et)
ZA (1) ZA200109676B (et)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2299879C2 (ru) 2000-01-17 2007-05-27 Байер Акциенгезелльшафт Замещенные арилкетоны
ES2172436B1 (es) * 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2002048105A2 (en) * 2000-11-16 2002-06-20 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
ES2201907B1 (es) * 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
CN1882565A (zh) * 2003-11-17 2006-12-20 贝林格尔.英格海姆国际有限公司 哌啶取代的吲哚或其杂环衍生物以及它们作为趋化因子－受体(ccr－3)调节剂的用途
US20050245540A1 (en) * 2003-12-09 2005-11-03 Fujisawa Pharmaceutical Co., Ltd. New methods
HU229709B1 (en) 2004-04-13 2014-05-28 Incyte Corp Wilmington Piperazinyilpiperidine derivatives as chemokine receptor antagonists
EA200700117A1 (ru) 2004-06-24 2007-06-29 Инсайт Корпорейшн N-замещенные пиперидины и их применение в качестве фармацевтических препаратов
JP2008504279A (ja) * 2004-06-24 2008-02-14 インサイト・コーポレイション アミド化合物およびその医薬としての使用
PT1877390E (pt) * 2005-04-26 2010-05-31 Hypnion Inc Compostos benzisoxazole-piridina e métodos para a sua utilização
WO2006117314A2 (en) 2005-04-30 2006-11-09 Boehringer Ingelheim International Gmbh Novel piperidin- substituted indoles and their use as ccr-3 modulators
US20060275516A1 (en) * 2005-06-02 2006-12-07 Ram A N S Compositions and methods for the treatment of allergic rhinitis
US20080108586A1 (en) * 2006-09-06 2008-05-08 Incyte Corporation Combination therapy for human immunodeficiency virus infection
JP5581055B2 (ja) * 2006-10-27 2014-08-27 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ピペリジル−プロパン−チオールｃｃｒ３モジュレーター
PE20090188A1 (es) * 2007-03-15 2009-03-20 Novartis Ag Compuestos heterociclicos como moduladores de la senda de hedgehog
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
CN101560179B (zh) * 2009-05-25 2012-04-18 浙江大学 具有h3受体亲和能力的含氮吲哚衍生物和用途
CN101747321B (zh) * 2009-12-22 2013-01-02 浙江大学 吲哚-3-苄胺衍生物及制备方法和用途
EP3040334A1 (en) * 2014-12-29 2016-07-06 Faes Farma, S.A. New benzimidazole derivatives as antihistamine agents
KR20240063881A (ko) * 2021-07-30 2024-05-13 콘포 테라퓨틱스 엔.브이. 통증, 특히 신경병증성 통증, 및/또는 at2r 및/또는 at2r 매개 신호전달과 연관된 다른 질환 또는 장애의 치료를 위한 화합물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
JPS63301881A (ja) * 1987-06-01 1988-12-08 Fujisawa Pharmaceut Co Ltd インドリルピペリジン誘導体
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8900382D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
CA2129995C (en) * 1992-02-13 2000-04-11 Albert A. Carr Piperidinyl thiacyclic derivatives
IT1271417B (it) * 1993-10-15 1997-05-28 Erregierre Ind Chim Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono.
DE19500689A1 (de) 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
DE19707628A1 (de) 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
AR028685A1 (es) * 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol

Also Published As

Publication number Publication date
CO5180556A1 (es) 2002-07-30
AU773164B2 (en) 2004-05-20
CZ20014334A3 (cs) 2002-03-13
NZ515649A (en) 2003-08-29
AR029640A1 (es) 2003-07-10
US20020147344A1 (en) 2002-10-10
KR100683454B1 (ko) 2007-02-20
KR20020020721A (ko) 2002-03-15
BR0011340A (pt) 2002-03-05
TWI226889B (en) 2005-01-21
CN1191246C (zh) 2005-03-02
CA2375985A1 (en) 2000-12-14
DE60008239T2 (de) 2004-11-18
IL146629A0 (en) 2002-07-25
TR200103490T2 (tr) 2002-04-22
HUP0203320A3 (en) 2004-01-28
ZA200109676B (en) 2003-02-24
MXPA01012425A (es) 2002-06-04
JP2003501424A (ja) 2003-01-14
DK1183251T3 (da) 2004-06-07
NO20015897D0 (no) 2001-12-03
US6683096B2 (en) 2004-01-27
ES2211559T3 (es) 2004-07-16
CN1368969A (zh) 2002-09-11
EE04717B1 (et) 2006-10-16
EP1183251B1 (en) 2004-02-11
ES2165274B1 (es) 2003-04-01
SK17042001A3 (sk) 2002-04-04
PL353164A1 (en) 2003-10-20
WO2000075130A1 (en) 2000-12-14
PL196774B1 (pl) 2008-01-31
NO20015897L (no) 2001-12-03
PE20010208A1 (es) 2001-03-19
EP1183251A1 (en) 2002-03-06
ES2165274A1 (es) 2002-03-01
RU2246493C2 (ru) 2005-02-20
AU5527600A (en) 2000-12-28
DE60008239D1 (de) 2004-03-18
BG106168A (bg) 2002-07-31
HUP0203320A2 (hu) 2003-02-28
MY127033A (en) 2006-11-30
SI1183251T1 (en) 2004-06-30
UA72517C2 (uk) 2005-03-15
PT1183251E (pt) 2004-05-31
RU2002100073A (ru) 2004-01-10
ATE259362T1 (de) 2004-02-15
HK1040990A1 (zh) 2002-06-28

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Legal Events

Date Code Title Description
HD1A Correction of address
KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

MM4A Lapsed by not paying the annual fees

Effective date: 20080531