ATE259362T1 - Indolylpiperidinderivate als antihistaminische und antiallergische mittel - Google Patents

Indolylpiperidinderivate als antihistaminische und antiallergische mittel

Info

Publication number
ATE259362T1
ATE259362T1 AT00940296T AT00940296T ATE259362T1 AT E259362 T1 ATE259362 T1 AT E259362T1 AT 00940296 T AT00940296 T AT 00940296T AT 00940296 T AT00940296 T AT 00940296T AT E259362 T1 ATE259362 T1 AT E259362T1
Authority
AT
Austria
Prior art keywords
anthistaminic
antiallergic agents
indolylpiperidine derivatives
indolylpiperidine
derivatives
Prior art date
Application number
AT00940296T
Other languages
English (en)
Inventor
Santacana Lluis Pages
Pou Silvia Fonquerna
Duran Carles Puig
Forner Dolors Fernandez
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of ATE259362T1 publication Critical patent/ATE259362T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT00940296T 1999-06-04 2000-05-31 Indolylpiperidinderivate als antihistaminische und antiallergische mittel ATE259362T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009901232A ES2165274B1 (es) 1999-06-04 1999-06-04 Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
PCT/EP2000/005010 WO2000075130A1 (en) 1999-06-04 2000-05-31 Indolylpiperidine derivatives as antihistaminic and antiallergic agents

Publications (1)

Publication Number Publication Date
ATE259362T1 true ATE259362T1 (de) 2004-02-15

Family

ID=8308707

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00940296T ATE259362T1 (de) 1999-06-04 2000-05-31 Indolylpiperidinderivate als antihistaminische und antiallergische mittel

Country Status (35)

Country Link
US (1) US6683096B2 (de)
EP (1) EP1183251B1 (de)
JP (1) JP2003501424A (de)
KR (1) KR100683454B1 (de)
CN (1) CN1191246C (de)
AR (1) AR029640A1 (de)
AT (1) ATE259362T1 (de)
AU (1) AU773164B2 (de)
BG (1) BG106168A (de)
BR (1) BR0011340A (de)
CA (1) CA2375985A1 (de)
CO (1) CO5180556A1 (de)
CZ (1) CZ20014334A3 (de)
DE (1) DE60008239T2 (de)
DK (1) DK1183251T3 (de)
EE (1) EE04717B1 (de)
ES (2) ES2165274B1 (de)
HK (1) HK1040990A1 (de)
HU (1) HUP0203320A3 (de)
IL (1) IL146629A0 (de)
MX (1) MXPA01012425A (de)
MY (1) MY127033A (de)
NO (1) NO20015897L (de)
NZ (1) NZ515649A (de)
PE (1) PE20010208A1 (de)
PL (1) PL196774B1 (de)
PT (1) PT1183251E (de)
RU (1) RU2246493C2 (de)
SI (1) SI1183251T1 (de)
SK (1) SK17042001A3 (de)
TR (1) TR200103490T2 (de)
TW (1) TWI226889B (de)
UA (1) UA72517C2 (de)
WO (1) WO2000075130A1 (de)
ZA (1) ZA200109676B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1509285A (zh) * 2000-01-17 2004-06-30 被取代的芳基酮类
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2002048105A2 (en) * 2000-11-16 2002-06-20 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
ES2201907B1 (es) 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
MXPA06004626A (es) 2003-11-17 2006-06-27 Boehringer Ingelheim Int Indoles sustituidos con piperidina o sus heteroderivados y su uso como moduladores del receptor de quemocina (ccr3).
US20050245540A1 (en) * 2003-12-09 2005-11-03 Fujisawa Pharmaceutical Co., Ltd. New methods
ES2431524T3 (es) * 2004-04-13 2013-11-26 Incyte Corporation Derivados de piperazinilpiperidina como antagonistas de los receptores de quimiocinas
US20060009491A1 (en) * 2004-06-24 2006-01-12 Incyte Corporation Amido compounds and their use as pharmaceuticals
WO2006012226A2 (en) 2004-06-24 2006-02-02 Incyte Corporation N-substituted piperidines and their use as pharmaceuticals
ATE461925T1 (de) * 2005-04-26 2010-04-15 Hypnion Inc Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
WO2006117314A2 (en) 2005-04-30 2006-11-09 Boehringer Ingelheim International Gmbh Novel piperidin- substituted indoles and their use as ccr-3 modulators
US20060275516A1 (en) * 2005-06-02 2006-12-07 Ram A N S Compositions and methods for the treatment of allergic rhinitis
WO2008030853A2 (en) * 2006-09-06 2008-03-13 Incyte Corporation Combination therapy for human immunodeficiency virus infection
ATE537166T1 (de) 2006-10-27 2011-12-15 Boehringer Ingelheim Int Piperidylpropanthiole als ccr3-modulatoren
US8536168B2 (en) 2007-03-15 2013-09-17 Novartis Ag Benzyl and pyridinyl derivatives as modulators of the hedgehog signaling pathway
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
CN101560179B (zh) * 2009-05-25 2012-04-18 浙江大学 具有h3受体亲和能力的含氮吲哚衍生物和用途
CN101747321B (zh) * 2009-12-22 2013-01-02 浙江大学 吲哚-3-苄胺衍生物及制备方法和用途
EP3040334A1 (de) * 2014-12-29 2016-07-06 Faes Farma, S.A. Neue Benzimidazolderivate als Antihistaminmittel
AU2022318349B2 (en) * 2021-07-30 2025-12-18 Confo Therapeutics N.V. Compounds for the treatment of pain, in particular neuropathic pain, and/or other diseases or disorders that are associated with at2r and/or at2r mediated signaling

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
JPS63301881A (ja) * 1987-06-01 1988-12-08 Fujisawa Pharmaceut Co Ltd インドリルピペリジン誘導体
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8800795D0 (en) * 1988-01-14 1988-02-17 Fujisawa Pharmaceutical Co New indolylpiperidine compounds processes for preparations thereof & pharmaceutical composition comprising same
GB8900382D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
DE69330823T2 (de) * 1992-02-13 2002-05-02 Merrell Pharmaceuticals Inc., Cincinnati Thiacyclische piperidinylderivate
IT1271417B (it) * 1993-10-15 1997-05-28 Erregierre Ind Chim Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono.
DE19500689A1 (de) 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
DE19707628A1 (de) 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
AR028685A1 (es) * 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol

Also Published As

Publication number Publication date
CO5180556A1 (es) 2002-07-30
ES2165274B1 (es) 2003-04-01
TR200103490T2 (tr) 2002-04-22
EE04717B1 (et) 2006-10-16
CN1368969A (zh) 2002-09-11
UA72517C2 (uk) 2005-03-15
SK17042001A3 (sk) 2002-04-04
EE200100653A (et) 2003-02-17
PT1183251E (pt) 2004-05-31
ES2211559T3 (es) 2004-07-16
CN1191246C (zh) 2005-03-02
HUP0203320A2 (hu) 2003-02-28
PL196774B1 (pl) 2008-01-31
MXPA01012425A (es) 2002-06-04
BG106168A (bg) 2002-07-31
AU773164B2 (en) 2004-05-20
ZA200109676B (en) 2003-02-24
NO20015897D0 (no) 2001-12-03
EP1183251A1 (de) 2002-03-06
NO20015897L (no) 2001-12-03
DK1183251T3 (da) 2004-06-07
AR029640A1 (es) 2003-07-10
DE60008239T2 (de) 2004-11-18
RU2002100073A (ru) 2004-01-10
PL353164A1 (en) 2003-10-20
KR100683454B1 (ko) 2007-02-20
US20020147344A1 (en) 2002-10-10
WO2000075130A1 (en) 2000-12-14
NZ515649A (en) 2003-08-29
HK1040990A1 (zh) 2002-06-28
AU5527600A (en) 2000-12-28
HUP0203320A3 (en) 2004-01-28
CA2375985A1 (en) 2000-12-14
RU2246493C2 (ru) 2005-02-20
MY127033A (en) 2006-11-30
KR20020020721A (ko) 2002-03-15
US6683096B2 (en) 2004-01-27
TWI226889B (en) 2005-01-21
SI1183251T1 (en) 2004-06-30
IL146629A0 (en) 2002-07-25
ES2165274A1 (es) 2002-03-01
JP2003501424A (ja) 2003-01-14
PE20010208A1 (es) 2001-03-19
DE60008239D1 (de) 2004-03-18
EP1183251B1 (de) 2004-02-11
CZ20014334A3 (cs) 2002-03-13
BR0011340A (pt) 2002-03-05

Similar Documents

Publication Publication Date Title
DE60026540D1 (de) Mutilin-derivate und ihre anwendung als antibakterielle mittel
DE60008239D1 (de) Indolylpiperidinderivate als antihistaminische und antiallergische mittel
DE60031513D1 (de) Phenyl- und pyridinyl-derivate verwendbar als neurokinin-1-antagonisten
DE60036803D1 (de) Arylmethyl-carbonylamino-thiazolderivate und ihre verwendung als antitumormittel
ATE359275T1 (de) Substituierte bizyclische derivate verwendbar als antitumor mittel
ATE413402T1 (de) Imidazoimidazole und -triazole als entzündungshemmende mittel
DE60039539D1 (de) 4-aminopiperidin-derivate und ihre verwendung als arzneimittel
DE60001107D1 (de) Sichere und handliche hinweisanordung
DE60016611D1 (de) Chinolinpropyl-piperidinderivate und deren verwendung als antibakterielle wirkstoffe
DE50112669D1 (de) Acridin-derivate und deren verwendung als arzneimittel
DE69720194D1 (de) Piperazinonphenyloxazolidinon derivate und ihre verwendung als antibakterielle mittel
DE60132618D1 (de) 4,6-diphenylpyridinderivate als entzündungshemmende mittel
ATE348805T1 (de) 2-acyl-indolderivate und deren verwendung als antitumormittel
DE60032898D1 (de) Arylthiazolidindion- und aryloxazolidinderivate
ATE326452T1 (de) Piperidinyloxy- und pyrrolidinyloxyphenyloxazolidinone als antibakterielle mittel
DE69903143D1 (de) Chromanon und thiochromanon derivate
ATE437860T1 (de) 2-hydroxy-mutilin-carbamat derivate und ihre anwendung als antibakterielle mittel
DE69917451D1 (de) Sulfonylbenzolverbindungen als analgetische und entzündungshemmende mittel
ATE309208T1 (de) 10-aryl-11h-benzo(b)fluoren-derivate und analoga als östrogene mittel
EE200200135A (et) D4 antagonistidena toimivad tienoisoksasolüül- jatienüülpürrasolüülfenoksü-asendatud propüülderivaadid
DE60023595D1 (de) Versorgungseinheit und Stromversorgungssystem
DE69921983D1 (de) Indolderivate als serotonergische mittel
DE60003072D1 (de) Thiazolidindion-derivate als antidiabetika
ATE321761T1 (de) Indolylpiperidinderivate als antihistaminische und antiallergische mittel
DE60010425D1 (de) Mittel gegen medikamentenresistente bakterienstämme und anti-chlamydiamittel

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1183251

Country of ref document: EP

REN Ceased due to non-payment of the annual fee