DE69720194D1 - Piperazinonphenyloxazolidinon derivate und ihre verwendung als antibakterielle mittel - Google Patents
Piperazinonphenyloxazolidinon derivate und ihre verwendung als antibakterielle mittelInfo
- Publication number
- DE69720194D1 DE69720194D1 DE69720194T DE69720194T DE69720194D1 DE 69720194 D1 DE69720194 D1 DE 69720194D1 DE 69720194 T DE69720194 T DE 69720194T DE 69720194 T DE69720194 T DE 69720194T DE 69720194 D1 DE69720194 D1 DE 69720194D1
- Authority
- DE
- Germany
- Prior art keywords
- piperazinonephenyloxazolidinone
- derivatives
- antibacterial agents
- antibacterial
- agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9601666.2A GB9601666D0 (en) | 1996-01-27 | 1996-01-27 | Chemical compounds |
PCT/GB1997/000169 WO1997027188A1 (en) | 1996-01-27 | 1997-01-21 | Piperazinonephenyloxazolidinone derivatives and their use as antibacterial agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69720194D1 true DE69720194D1 (de) | 2003-04-30 |
DE69720194T2 DE69720194T2 (de) | 2003-12-24 |
Family
ID=10787670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69720194T Expired - Fee Related DE69720194T2 (de) | 1996-01-27 | 1997-01-21 | Piperazinonphenyloxazolidinon derivate und ihre verwendung als antibakterielle mittel |
Country Status (7)
Country | Link |
---|---|
US (1) | US6069145A (de) |
EP (1) | EP0882041B1 (de) |
JP (1) | JP2000503981A (de) |
AU (1) | AU1315797A (de) |
DE (1) | DE69720194T2 (de) |
GB (1) | GB9601666D0 (de) |
WO (1) | WO1997027188A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
GB9609919D0 (en) | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
US6255304B1 (en) * | 1997-05-30 | 2001-07-03 | Pharmacia & Upjohn Company | Oxazolidinone antibacterial agents having a thiocarbonyl functionality |
US6037354A (en) * | 1997-06-18 | 2000-03-14 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
GB9717807D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
DK1030852T3 (da) * | 1997-11-12 | 2003-12-22 | Upjohn Co | Oxazolidinonderivater og farmaceutiske præparater |
GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
BR9907183A (pt) | 1998-01-23 | 2003-06-10 | Versicor Inc | Colet neas combinatórias de oxazolidinona, composições e processos de preparação |
US6562844B2 (en) | 1998-01-23 | 2003-05-13 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
US7002020B1 (en) | 1998-01-23 | 2006-02-21 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
US6465456B2 (en) | 2000-06-29 | 2002-10-15 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
PE20020300A1 (es) * | 2000-08-22 | 2002-05-10 | Pharmacia Corp | Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco |
PE20020578A1 (es) | 2000-10-10 | 2002-08-14 | Upjohn Co | Una composicion de antibiotico topico para el tratamiento de infecciones oculares |
YU52403A (sh) | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže |
US7160912B2 (en) | 2000-12-26 | 2007-01-09 | Dr.Reddy's Laboratories Ltd. | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them |
DE60205030T2 (de) | 2001-09-11 | 2006-04-20 | Astrazeneca Ab | Oxazolidinon- und/oder isoxazolinderivate als antibakterielle mittel |
WO2003035073A1 (en) | 2001-10-25 | 2003-05-01 | Astrazeneca Ab | Isoxazoline derivatives useful as antimicrobials |
BR0307898A (pt) * | 2002-02-22 | 2004-12-07 | Pharmacia Corp | Formulações de droga antibiótica oftálmica contendo um composto de ciclodextrina e cloreto de cetil piridìnio |
AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
WO2003072576A2 (en) | 2002-02-28 | 2003-09-04 | Astrazeneca Ab | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them |
WO2003072575A1 (en) | 2002-02-28 | 2003-09-04 | Astrazeneca Ab | 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents |
WO2004014897A1 (en) * | 2002-08-12 | 2004-02-19 | Pharmacia & Upjohn Company Llc | N-aryl-2-oxazolidinones and their derivatives |
AR042086A1 (es) * | 2002-11-21 | 2005-06-08 | Upjohn Co | N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos |
US20040170686A1 (en) * | 2003-01-31 | 2004-09-02 | Fredrickson Jennifer K. | Suspension vehicle for coated drug particles |
EP1594494A1 (de) * | 2003-02-07 | 2005-11-16 | Warner-Lambert Company LLC | Mittels bizyklischem ring n-substituierte oxazolidinon-derivate zur verwendung als antibakterielle wirkstoffe |
JP2006516991A (ja) * | 2003-02-07 | 2006-07-13 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 抗菌剤 |
US20040191326A1 (en) * | 2003-03-31 | 2004-09-30 | Reo Joseph P. | Taste-masking vehicle for coated oxazolidinone particles |
US20040204463A1 (en) * | 2003-04-01 | 2004-10-14 | Harris Christina Renee | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
US20080262056A1 (en) * | 2004-08-06 | 2008-10-23 | Pfizer Inc | Oxindole Oxazolidinones as Antibacterial Agents |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4348393A (en) * | 1978-06-09 | 1982-09-07 | Delalande S.A. | N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones |
FR2458547B2 (fr) * | 1978-06-09 | 1986-05-16 | Delalande Sa | Nouvelles n-aryle azolones, leur procede de preparation et leur application en therapeutique |
CH647772A5 (fr) * | 1979-05-07 | 1985-02-15 | Delalande Sa | Derives de la 5h-furanone-2 et de la 3h-dihydro-furanone-2, leurs procedes de preparation, et medicament les contenant. |
FR2456097A1 (fr) * | 1979-05-07 | 1980-12-05 | Delalande Sa | Nouveaux derives de la 5 h-furanone-2 et de la 3 h-dihydrofuranone-2, leur procede de preparation et leur application en therapeutique |
FR2500450A1 (fr) * | 1981-02-25 | 1982-08-27 | Delalande Sa | Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique |
ES8506659A1 (es) * | 1983-06-07 | 1985-08-01 | Du Pont | Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno. |
US4705799A (en) * | 1983-06-07 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents |
CA1260948A (en) * | 1984-12-05 | 1989-09-26 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents |
CA1320730C (en) * | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
US4948801A (en) * | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
DE68918792T2 (de) * | 1988-09-15 | 1995-03-30 | Upjohn Co | 5-Indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(Nitrogen-substituierte)phenyl-5-beta-amidomethyloxazolidin-2-one. |
US5182403A (en) * | 1988-09-15 | 1993-01-26 | The Upjohn Company | Substituted 3(5'indazolyl) oxazolidin-2-ones |
US5164510A (en) * | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
US5231188A (en) * | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
ATE146783T1 (de) * | 1991-11-01 | 1997-01-15 | Upjohn Co | Substituierte aryl- und heteroaryl- phenyloxazolidinone |
SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
KR950702417A (ko) * | 1992-07-08 | 1995-07-29 | 로렌스 티. 웰츠 | 마이코박테륨 투베르쿨로시스에 대해 유용한 5′-인돌리닐 옥사졸리디논(5′-indolinyl oxazolidinones useful against mycobacterium tuberculosis) |
ES2111188T3 (es) * | 1992-12-08 | 1998-03-01 | Upjohn Co | Agentes antibacterianos derivados de feniloxazolidinona sustituida con tropona. |
MY115155A (en) * | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
CA2174107C (en) * | 1993-11-22 | 2005-04-12 | Steven J. Brickner | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
TW286317B (de) * | 1993-12-13 | 1996-09-21 | Hoffmann La Roche | |
JPH0873455A (ja) * | 1994-03-15 | 1996-03-19 | Upjohn Co:The | オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物 |
DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
DE4425612A1 (de) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
DE4425609A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | Benzofuranyl- und Benzothienyloxazolidinone |
DE19514313A1 (de) * | 1994-08-03 | 1996-02-08 | Bayer Ag | Benzoxazolyl- und Benzothiazolyloxazolidinone |
BR9509136A (pt) * | 1994-10-26 | 1998-07-21 | Upjohn Co | Composto e uso do mesmo |
MX9703543A (es) * | 1994-11-15 | 1997-08-30 | Upjohn Co | Antibacterianos de oxazina biciclica y oxazolidinona tiazina. |
DE69615002T2 (de) * | 1995-02-03 | 2002-06-13 | Pharmacia & Upjohn Co., Kalamazoo | Durch hetero-aromatische ring substituierte phenyloxazolidinone als antimikrobielles mittel |
HRP960159A2 (en) * | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
MX9708627A (es) * | 1995-05-11 | 1998-02-28 | Upjohn Co | Oxazolidinonas de diazinilo y carbazinilo espirociclicas y biciclicas. |
SK283487B6 (sk) * | 1995-09-01 | 2003-08-05 | Pharmacia And Upjohn Company | Fenyloxazolidinóny majúce C-C väzbu v 4 až 8 členných heterocyklických kruhoch |
ES2185800T3 (es) * | 1995-09-15 | 2003-05-01 | Upjohn Co | Agentes antibacterianos basados en 5-amidometilo, 3-arilo butirolactona alfa, beta saturada e insaturada. |
DE69631347T2 (de) * | 1995-09-15 | 2004-10-07 | Upjohn Co | Aminoaryl oxazolidinone n-oxide |
GB9521508D0 (en) * | 1995-10-20 | 1995-12-20 | Zeneca Ltd | Chemical compounds |
ZA968661B (en) * | 1995-11-17 | 1998-04-14 | Upjohn Co | Oxazolidinone antibacterial agent with tricyclic substituents. |
ZA969622B (en) * | 1995-12-13 | 1998-05-15 | Upjohn Co | Oxazolidinone antibacterial agents having a six-membered heteroaromatic ring. |
DE19601265A1 (de) * | 1996-01-16 | 1997-07-17 | Bayer Ag | 2-Oxo- und 2-Thio-1,2-dihydrochinolinyl-oxazolidinone |
DE19601264A1 (de) * | 1996-01-16 | 1997-07-17 | Bayer Ag | Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone |
DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
DE19649095A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue Heteroaryl-Oxazolidinone |
MY116093A (en) * | 1996-02-26 | 2003-11-28 | Upjohn Co | Azolyl piperazinyl phenyl oxazolidinone antimicrobials |
SK284703B6 (sk) * | 1996-04-11 | 2005-09-08 | Pharmacia & Upjohn Company | Spôsob prípravy substituovaných oxazolidinón alkoholov |
ATE227277T1 (de) * | 1996-08-21 | 2002-11-15 | Upjohn Co | Isoxazoline derivate und ihre verwendung als antimikroben |
-
1996
- 1996-01-27 GB GBGB9601666.2A patent/GB9601666D0/en active Pending
-
1997
- 1997-01-21 US US09/117,337 patent/US6069145A/en not_active Expired - Fee Related
- 1997-01-21 JP JP9526640A patent/JP2000503981A/ja active Pending
- 1997-01-21 AU AU13157/97A patent/AU1315797A/en not_active Abandoned
- 1997-01-21 DE DE69720194T patent/DE69720194T2/de not_active Expired - Fee Related
- 1997-01-21 WO PCT/GB1997/000169 patent/WO1997027188A1/en active IP Right Grant
- 1997-01-21 EP EP97900692A patent/EP0882041B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU1315797A (en) | 1997-08-20 |
JP2000503981A (ja) | 2000-04-04 |
US6069145A (en) | 2000-05-30 |
EP0882041A1 (de) | 1998-12-09 |
GB9601666D0 (en) | 1996-03-27 |
WO1997027188A1 (en) | 1997-07-31 |
EP0882041B1 (de) | 2003-03-26 |
DE69720194T2 (de) | 2003-12-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |