ES2241324T3
(es)
|
1998-10-08 |
2005-10-16 |
Astrazeneca Ab |
Derivados de quinazolina.
|
UA71945C2
(en)
*
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
DK1154774T3
(da)
|
1999-02-10 |
2005-09-26 |
Astrazeneca Ab |
Quinazolinderivater som angiogenesisinhibitorer
|
US7071199B1
(en)
|
1999-09-17 |
2006-07-04 |
Abbott Gmbh & Cco. Kg |
Kinase inhibitors as therapeutic agents
|
DE60037455T2
(de)
*
|
1999-09-17 |
2008-11-27 |
Abbott Gmbh & Co. Kg |
Kinaseinhibitoren als arzneimittel
|
YU95102A
(sh)
*
|
2000-06-22 |
2005-11-28 |
Pfizer Products Inc. |
Supstituisani biciklični derivati u lečenju abnormalnog rasta ćelija
|
IL153947A0
(en)
|
2000-08-09 |
2003-07-31 |
Astrazeneca Ab |
Quinoline derivatives having vegf inhibiting activity
|
ATE355275T1
(de)
|
2000-10-20 |
2006-03-15 |
Eisai R&D Man Co Ltd |
Stickstoff-enthaltende aromatische ringverbindungen zur behandlung von tumorerkrankungen
|
MXPA03008658A
(es)
*
|
2001-03-23 |
2005-04-11 |
Bayer Ag |
Inhibidores de rho-cinasa.
|
AR035792A1
(es)
*
|
2001-03-23 |
2004-07-14 |
Bayer Corp |
Compuestos de n-(4-quinazolinil)-n-(1h-indazol-5-il) amina, inhibidor de la rho-quinasa, su uso para la fabricacion de un medicamento y metodo para prepararlo
|
DE60212487T2
(de)
*
|
2001-04-13 |
2006-12-21 |
Pfizer Products Inc., Groton |
Bizyklisch substituierte 4-Aminopyridopyrimidinderivate
|
WO2003000194A2
(en)
|
2001-06-21 |
2003-01-03 |
Pfizer Inc. |
Thienopyridine and thienopyrimidine anticancer agents
|
BR0213842A
(pt)
*
|
2001-11-03 |
2004-08-31 |
Astrazeneca Ab |
Derivado de quinazolina ou um sal deste farmaceuticamente aceitável, processo para a preparação do mesmo, composição farmacêutica, e, uso do derivado de quinazolina ou de um sal deste farmaceuticamente aceitável
|
GB0126433D0
(en)
*
|
2001-11-03 |
2002-01-02 |
Astrazeneca Ab |
Compounds
|
ES2295409T3
(es)
*
|
2001-11-30 |
2008-04-16 |
Osi Pharmaceuticals, Inc. |
Procedimiento para la preparacion de derivados biciclicos sustituidos para el tratamiento de crecimiento anormal de celulas.
|
WO2003049740A1
(en)
*
|
2001-12-12 |
2003-06-19 |
Pfizer Products Inc. |
Quinazoline derivatives for the treatment of abnormal cell growth
|
AU2002357193A1
(en)
*
|
2001-12-19 |
2003-07-09 |
Smithkline Beecham Corporation |
Thienopyrimidine compounds as protein tyrosine kinase inhibitors
|
US20030143165A1
(en)
*
|
2002-01-25 |
2003-07-31 |
Allan Evans |
NSAID-containing topical formulations that demonstrate chemopreventive activity
|
KR101093345B1
(ko)
|
2002-02-01 |
2011-12-14 |
아스트라제네카 아베 |
퀴나졸린 화합물
|
TW200302722A
(en)
*
|
2002-02-13 |
2003-08-16 |
Astrazeneca Ab |
Therapeutic agents
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
JP2005524712A
(ja)
*
|
2002-05-07 |
2005-08-18 |
ニューロサーチ、アクティーゼルスカブ |
新規アザシクロエチニル誘導体
|
ES2369640T3
(es)
*
|
2002-05-24 |
2011-12-02 |
Angiotech International Ag |
Composiciones y métodos para revestir implantes médicos.
|
US8313760B2
(en)
*
|
2002-05-24 |
2012-11-20 |
Angiotech International Ag |
Compositions and methods for coating medical implants
|
ATE323702T1
(de)
|
2002-08-06 |
2006-05-15 |
Astrazeneca Ab |
Kondensierte pyridine und pyrimidine mit tie2 (tek) aktivität
|
AU2003291394B2
(en)
|
2002-11-20 |
2009-06-25 |
Array Biopharma, Inc |
Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
|
US20040186160A1
(en)
*
|
2002-12-13 |
2004-09-23 |
Sugen, Inc. |
Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors
|
BR0317433A
(pt)
*
|
2002-12-18 |
2005-11-16 |
Pfizer Prod Inc |
Derivados bicìclicos para o tratamento do crescimento celular anormal
|
SI1585743T1
(sl)
*
|
2002-12-19 |
2007-08-31 |
Pfizer |
Spojine 2-(1H-indazol-6-ilamino)-benzamida kot inhibitorji protein-kinaz, uporabnih pri zdravljenju očesnih bolezni
|
GB0309009D0
(en)
*
|
2003-04-22 |
2003-05-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
GB0309850D0
(en)
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
MXPA05012839A
(es)
*
|
2003-05-27 |
2006-05-17 |
Pfizer Prod Inc |
Quinazolinas y pirido[3,4-d] pirimidinas como inhibidores de receptores tirosina quinasa.
|
WO2006074147A2
(en)
|
2005-01-03 |
2006-07-13 |
Myriad Genetics, Inc. |
Nitrogen containing bicyclic compounds and therapeutical use thereof
|
US8309562B2
(en)
|
2003-07-03 |
2012-11-13 |
Myrexis, Inc. |
Compounds and therapeutical use thereof
|
WO2005003100A2
(en)
*
|
2003-07-03 |
2005-01-13 |
Myriad Genetics, Inc. |
4-arylamino-quinazolines as activators of caspases and inducers of apoptosis
|
HN2004000285A
(es)
*
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
MXPA06002963A
(es)
*
|
2003-09-16 |
2006-06-14 |
Astrazeneca Ab |
Derivados de quinazolina como inhibidores de cinasa de tirosina.
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
WO2005044788A1
(ja)
|
2003-11-11 |
2005-05-19 |
Eisai Co., Ltd. |
ウレア誘導体およびその製造方法
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
CA2536242A1
(en)
*
|
2003-11-20 |
2005-06-09 |
Angiotech International Ag |
Implantable sensors and implantable pumps and anti-scarring agents
|
GB0330002D0
(en)
|
2003-12-24 |
2004-01-28 |
Astrazeneca Ab |
Quinazoline derivatives
|
CN1914182B
(zh)
|
2004-02-03 |
2011-09-07 |
阿斯利康(瑞典)有限公司 |
喹唑啉衍生物
|
JP2007530654A
(ja)
*
|
2004-03-30 |
2007-11-01 |
ファイザー・プロダクツ・インク |
シグナル伝達阻害剤の組合せ
|
JPWO2005095419A1
(ja)
*
|
2004-04-01 |
2008-02-21 |
武田薬品工業株式会社 |
チアゾロピリミジン誘導体
|
RU2389731C2
(ru)
*
|
2004-06-02 |
2010-05-20 |
Такеда Фармасьютикал Компани Лимитед |
Конденсированное гетероциклическое соединение
|
US20070232607A1
(en)
*
|
2004-06-04 |
2007-10-04 |
Bradbury Robert H |
Quinazoline Derivatives as Erbb Receptor Tyrosine kinases
|
BRPI0513405A
(pt)
*
|
2004-07-16 |
2008-05-06 |
Sunesis Pharmaceuticals Inc |
tienopirimidinas úteis como inibidores de aurora quinase
|
TW200615268A
(en)
*
|
2004-08-02 |
2006-05-16 |
Osi Pharm Inc |
Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds
|
JP4242911B2
(ja)
|
2004-08-26 |
2009-03-25 |
ファイザー・インク |
プロテインキナーゼ阻害薬としてのエナンチオピュアなアミノヘテロアリール化合物
|
ME01309B
(me)
*
|
2004-08-26 |
2013-12-20 |
Pfizer |
Pirazolom supstituirani heteroarilni spojevi kao inhibitori proteinskih kinaza
|
CA2578075A1
(en)
*
|
2004-08-26 |
2006-03-02 |
Pfizer Inc. |
Aminoheteroaryl compounds as protein tyrosine kinase inhibitors
|
AU2005283422C1
(en)
|
2004-09-17 |
2017-02-02 |
Eisai R & D Management Co., Ltd. |
Medicinal composition
|
US7285569B2
(en)
|
2004-09-24 |
2007-10-23 |
Hoff Hoffmann-La Roche Inc. |
Tricycles, their manufacture and use as pharmaceutical agents
|
TW200624431A
(en)
|
2004-09-24 |
2006-07-16 |
Hoffmann La Roche |
Phthalazinone derivatives, their manufacture and use as pharmaceutical agents
|
US20060107555A1
(en)
*
|
2004-11-09 |
2006-05-25 |
Curtis Marc D |
Universal snow plow adapter
|
CN101124228B
(zh)
|
2004-12-14 |
2011-06-15 |
阿斯利康(瑞典)有限公司 |
用作抗肿瘤药物的吡唑并嘧啶化合物
|
KR20070117547A
(ko)
*
|
2005-01-03 |
2007-12-12 |
미리어드 제네틱스, 인크. |
뇌암 치료방법
|
US8258145B2
(en)
|
2005-01-03 |
2012-09-04 |
Myrexis, Inc. |
Method of treating brain cancer
|
GB0504474D0
(en)
*
|
2005-03-04 |
2005-04-13 |
Astrazeneca Ab |
Chemical compounds
|
EP2444099A1
(de)
|
2005-03-31 |
2012-04-25 |
Agensys, Inc. |
An 161P2F10B-Proteine bindende Antikörper und zugehörige Moleküle
|
US7462639B2
(en)
|
2005-04-14 |
2008-12-09 |
Hoffmann-La Roche Inc. |
Aminopyrazole derivatives
|
CA2604357C
(en)
|
2005-04-26 |
2012-01-17 |
Pfizer Inc. |
P-cadherin antibodies
|
GB0508715D0
(en)
*
|
2005-04-29 |
2005-06-08 |
Astrazeneca Ab |
Chemical compounds
|
GB0508717D0
(en)
*
|
2005-04-29 |
2005-06-08 |
Astrazeneca Ab |
Chemical compounds
|
CA2610655A1
(en)
|
2005-06-03 |
2006-12-14 |
Abbott Laboratories |
Cyclobutyl amine derivatives
|
EP1925676A4
(de)
|
2005-08-02 |
2010-11-10 |
Eisai R&D Man Co Ltd |
Testverfahren für die wirkung eines vaskularisierungsinhibitors
|
EA201300320A1
(ru)
|
2005-09-07 |
2014-02-28 |
Эмджен Фримонт Инк. |
Моноклональные антитела человека к киназе-1, подобной рецептору активина
|
JP2009508917A
(ja)
*
|
2005-09-20 |
2009-03-05 |
アストラゼネカ アクチボラグ |
抗癌剤としてのキナゾリン誘導体
|
EP1928861B1
(de)
*
|
2005-09-20 |
2010-11-17 |
AstraZeneca AB |
4-(1h-indazol-5-ylamino)chinazolinverbindungen als inhibitoren der erbb-rezeptortyrosinkinase zur behandlung von krebs
|
WO2007035744A1
(en)
|
2005-09-20 |
2007-03-29 |
Osi Pharmaceuticals, Inc. |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
US7576110B2
(en)
|
2005-09-22 |
2009-08-18 |
Abbott Laboratories |
Benzothiazole cyclobutyl amine derivatives
|
TW200730527A
(en)
*
|
2005-12-02 |
2007-08-16 |
Takeda Pharmaceuticals Co |
Fused heterocyclic compound
|
WO2007063293A1
(en)
*
|
2005-12-02 |
2007-06-07 |
Astrazeneca Ab |
Quinazoleine derivatives used as inhibitors of erbb tyrosine kinase
|
EP1957499A1
(de)
*
|
2005-12-02 |
2008-08-20 |
AstraZeneca AB |
4-anilinosubstituierte chinazolinderivate als tyrosinkinaseinhibitoren
|
JP2009531274A
(ja)
*
|
2005-12-07 |
2009-09-03 |
オーエスアイ・ファーマスーティカルズ・インコーポレーテッド |
キナーゼ阻害性ピロロピリジン化合物
|
US7572809B2
(en)
|
2005-12-19 |
2009-08-11 |
Hoffmann-La Roche Inc. |
Isoquinoline aminopyrazole derivatives
|
DE602006015861D1
(de)
|
2005-12-21 |
2010-09-09 |
Abbott Lab |
Antivirale verbindungen
|
AU2006330924B2
(en)
|
2005-12-21 |
2012-03-15 |
Abbvie Inc. |
Anti-viral compounds
|
WO2007081517A2
(en)
|
2005-12-21 |
2007-07-19 |
Abbott Laboratories |
Anti-viral compounds
|
US20070231298A1
(en)
*
|
2006-03-31 |
2007-10-04 |
Cell Genesys, Inc. |
Cytokine-expressing cancer immunotherapy combinations
|
UA91129C2
(ru)
|
2006-05-09 |
2010-06-25 |
Пфайзер Продактс Инк. |
Производные циклоалкиламинокислот и фармацевтическая композиция, которая их содержит
|
CN101443009A
(zh)
|
2006-05-18 |
2009-05-27 |
卫材R&D管理有限公司 |
针对甲状腺癌的抗肿瘤剂
|
US9108948B2
(en)
|
2006-06-23 |
2015-08-18 |
Abbvie Inc. |
Cyclopropyl amine derivatives
|
WO2007150010A2
(en)
|
2006-06-23 |
2007-12-27 |
Abbott Laboratories |
Cyclopropyl amine derivatives as histamin h3 receptor modulators
|
EP2065372B1
(de)
|
2006-08-28 |
2012-11-28 |
Eisai R&D Management Co., Ltd. |
Antitumormittel gegen undifferenzierten magenkrebs
|
EP1921070A1
(de)
|
2006-11-10 |
2008-05-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung
|
CN101611041A
(zh)
|
2006-12-12 |
2009-12-23 |
武田药品工业株式会社 |
稠合杂环化合物
|
US8236950B2
(en)
|
2006-12-20 |
2012-08-07 |
Abbott Laboratories |
Anti-viral compounds
|
WO2008093855A1
(ja)
|
2007-01-29 |
2008-08-07 |
Eisai R & D Management Co., Ltd. |
未分化型胃癌治療用組成物
|
KR100799821B1
(ko)
*
|
2007-02-05 |
2008-01-31 |
동화약품공업주식회사 |
신규한 이마티닙 캠실레이트 및 그의 제조방법
|
AU2008212999A1
(en)
|
2007-02-06 |
2008-08-14 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
|
EP2137535B1
(de)
*
|
2007-04-13 |
2015-06-03 |
Dana-Farber Cancer Institute, Inc. |
Profilerstellung von rezeptor-tyrosinkinasen
|
CA2683559C
(en)
|
2007-04-13 |
2019-09-24 |
Dana Farber Cancer Institute, Inc. |
Methods for treating cancer resistant to erbb therapeutics
|
CN101687840A
(zh)
|
2007-06-25 |
2010-03-31 |
霍夫曼-拉罗奇有限公司 |
作为激酶抑制剂的苯并咪唑酰胺基衍生物
|
CA2698287A1
(en)
|
2007-09-07 |
2009-03-12 |
Agensys, Inc. |
Antibodies and related molecules that bind to 24p4c12 proteins
|
CA2704000C
(en)
|
2007-11-09 |
2016-12-13 |
Eisai R&D Management Co., Ltd. |
Combination of anti-angiogenic substance and anti-tumor platinum complex
|
EP2245026B1
(de)
|
2008-02-07 |
2012-08-01 |
Boehringer Ingelheim International GmbH |
Spirocyclische heterocyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
US7932036B1
(en)
|
2008-03-12 |
2011-04-26 |
Veridex, Llc |
Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase
|
UY31704A
(es)
|
2008-03-12 |
2009-11-10 |
Takeda Pharmaceutical |
Compuesto heterociclico fusionado
|
NZ589883A
(en)
|
2008-05-13 |
2012-06-29 |
Astrazeneca Ab |
Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6- { [1- (n-methylcarbamoylmethyl) piperidin- 4-yl] oxy} quinazoline
|
JP2011525915A
(ja)
*
|
2008-06-26 |
2011-09-29 |
アムジエン・インコーポレーテツド |
キナーゼ阻害薬としてのアルキニルアルコール類
|
WO2010011349A2
(en)
*
|
2008-07-25 |
2010-01-28 |
Supergen, Inc. |
Pyrimidine-2,4-diamine jak2 kinase inhibiting anti-inflammation use
|
US8648191B2
(en)
|
2008-08-08 |
2014-02-11 |
Boehringer Ingelheim International Gmbh |
Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
|
AR073501A1
(es)
|
2008-09-08 |
2010-11-10 |
Boehringer Ingelheim Int |
Derivados de pirimido[5,4-d]pirimidina inhibidores de la tirosinoquinasa
|
EP2241565A1
(de)
|
2009-01-15 |
2010-10-20 |
Universität Leipzig |
Aurora-Kinase-Inhibitor-Verbindungen
|
US20100204221A1
(en)
*
|
2009-02-09 |
2010-08-12 |
Hariprasad Vankayalapati |
Pyrrolopyrimidinyl axl kinase inhibitors
|
US20120189641A1
(en)
|
2009-02-25 |
2012-07-26 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
JP2012519170A
(ja)
|
2009-02-26 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
生体内の腫瘍細胞のemtステータスをモニターするためのinsitu法
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
WO2010099364A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
EP2401614A1
(de)
|
2009-02-27 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Verfahren zur identifizierung von mesenchymähnlichen tumorzellen oder deren bildung hemmenden stoffen
|
US20100222381A1
(en)
|
2009-02-27 |
2010-09-02 |
Hariprasad Vankayalapati |
Cyclopentathiophene/cyclohexathiophene DNA methyltransferase inhibitors
|
US9186353B2
(en)
|
2009-04-27 |
2015-11-17 |
Abbvie Inc. |
Treatment of osteoarthritis pain
|
EP2473500A2
(de)
|
2009-09-01 |
2012-07-11 |
Pfizer Inc. |
Benzimidazolderivate
|
US20110275644A1
(en)
|
2010-03-03 |
2011-11-10 |
Buck Elizabeth A |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
CA2783665A1
(en)
|
2010-03-03 |
2011-09-09 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
|
ES2573515T3
(es)
|
2010-06-25 |
2016-06-08 |
Eisai R&D Management Co., Ltd. |
Agente antitumoral que emplea compuestos con efecto inhibitorio de cinasas combinados
|
WO2012016021A2
(en)
|
2010-07-28 |
2012-02-02 |
Veridex, Llc |
Methods of determining acute myeloid leukemia response to treatment with farnesyltransferase inhibitors
|
US8853390B2
(en)
|
2010-09-16 |
2014-10-07 |
Abbvie Inc. |
Processes for preparing 1,2-substituted cyclopropyl derivatives
|
US9056865B2
(en)
|
2010-10-20 |
2015-06-16 |
Pfizer Inc. |
Pyridine-2-derivatives as smoothened receptor modulators
|
SG190784A1
(en)
*
|
2010-11-09 |
2013-07-31 |
Fujian Haixi Pharmaceuticals Inc |
Compound for increasing kinase active and application thereof
|
US20120214830A1
(en)
|
2011-02-22 |
2012-08-23 |
OSI Pharmaceuticals, LLC |
Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma
|
RU2580609C2
(ru)
|
2011-04-18 |
2016-04-10 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Противоопухолевое терапевтическое средство
|
EP3536708A1
(de)
|
2011-04-19 |
2019-09-11 |
Pfizer Inc |
Kombinationen aus anti-4-1bb-antikörpern und adcc-induzierenden antikörpern zur behandlung von krebs
|
EP2702173A1
(de)
|
2011-04-25 |
2014-03-05 |
OSI Pharmaceuticals, LLC |
Verwendung von emt-gensignaturen bei der entdeckung von krebswirkstoffen, -diagnostika und -behandlungen
|
ES2841809T3
(es)
|
2011-06-03 |
2021-07-09 |
Eisai R&D Man Co Ltd |
Biomarcadores para pronosticar y evaluar el grado de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib
|
WO2013013188A1
(en)
|
2011-07-21 |
2013-01-24 |
Tolero Pharmaceuticals, Inc. |
Heterocyclic protein kinase inhibitors
|
CN103814030A
(zh)
|
2011-09-22 |
2014-05-21 |
辉瑞大药厂 |
吡咯并嘧啶及嘌呤衍生物
|
MX2014005570A
(es)
|
2011-11-08 |
2014-05-30 |
Pfizer |
El uso de anticuerpos anti factor estimulante de la colonia de macrofagos para tratar trastornos inflamatorios.
|
TWI577671B
(zh)
*
|
2011-11-14 |
2017-04-11 |
Sunshine Lake Pharma Co Ltd |
Aminoquinazoline derivatives and salts thereof and methods of use thereof
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
JP6243918B2
(ja)
|
2012-10-16 |
2017-12-06 |
トレロ ファーマシューティカルズ, インコーポレイテッド |
Pkm2調節因子およびそれらの使用方法
|
US9260426B2
(en)
|
2012-12-14 |
2016-02-16 |
Arrien Pharmaceuticals Llc |
Substituted 1H-pyrrolo [2, 3-b] pyridine and 1H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
|
AU2013364953A1
(en)
|
2012-12-21 |
2015-04-30 |
Eisai R&D Management Co., Ltd. |
Amorphous form of quinoline derivative, and method for producing same
|
US9468681B2
(en)
|
2013-03-01 |
2016-10-18 |
California Institute Of Technology |
Targeted nanoparticles
|
WO2014151871A2
(en)
|
2013-03-14 |
2014-09-25 |
Tolero Pharmaceuticals, Inc. |
Jak2 and alk2 inhibitors and methods for their use
|
US9206188B2
(en)
|
2013-04-18 |
2015-12-08 |
Arrien Pharmaceuticals Llc |
Substituted pyrrolo[2,3-b]pyridines as ITK and JAK inhibitors
|
US10517861B2
(en)
|
2013-05-14 |
2019-12-31 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
UA115388C2
(uk)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-заміщені пуринові похідні та їх застосування в лікуванні проліферативних захворювань
|
CN103784412A
(zh)
*
|
2014-01-15 |
2014-05-14 |
青岛市肿瘤医院 |
一种盐酸埃克替尼分散片及其制备方法
|
WO2015155624A1
(en)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dihydropyrrolopyrimidine derivatives
|
BR112016024513A2
(pt)
|
2014-04-30 |
2017-08-15 |
Pfizer |
derivados de di-heterociclo ligados à cicloalquila
|
WO2016001789A1
(en)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
HRP20221047T1
(hr)
|
2014-08-28 |
2022-11-11 |
Eisai R&D Management Co., Ltd. |
Derivat kinolina visoke čistoće i postupak za njegovu proizvodnju
|
FI3263106T3
(fi)
|
2015-02-25 |
2024-01-03 |
Eisai R&D Man Co Ltd |
Menetelmä kinoliinijohdannaisen kitkeryyden tukahduttamiseksi
|
CA2978226A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharpe & Dohme Corp. |
Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
|
JP6851978B2
(ja)
|
2015-04-20 |
2021-03-31 |
スミトモ ダイニッポン ファーマ オンコロジー, インコーポレイテッド |
ミトコンドリアプロファイリングによるアルボシジブ応答の予測
|
TR201911032T4
(tr)
|
2015-05-18 |
2019-08-21 |
Tolero Pharmaceuticals Inc |
Artırılmış biyoyararlanıma sahip alvocıdıb ön ilaçları.
|
CA2988707C
(en)
|
2015-06-16 |
2023-10-10 |
Eisai R&D Management Co., Ltd. |
Combination of cbp/catenin inhibitor and immune checkpoint inhibitor for treating cancer
|
EP3317323B1
(de)
|
2015-07-01 |
2021-05-26 |
California Institute of Technology |
Kationische schleimsäurepolymerbasierte abgabesysteme
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
RU2759963C2
(ru)
|
2015-08-03 |
2021-11-19 |
Сумитомо Даиниппон Фарма Онколоджи, Инк. |
Комбинированные терапии для лечения рака
|
AU2016364855B2
(en)
|
2015-12-03 |
2019-08-29 |
Les Laboratoires Servier |
MAT2A inhibitors for treating MTAP null cancer
|
WO2018094275A1
(en)
|
2016-11-18 |
2018-05-24 |
Tolero Pharmaceuticals, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
EP3362471B1
(de)
|
2016-12-19 |
2021-11-17 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Profilierung von peptiden und verfahren zur sensitivitätsprofilierung
|
US11497756B2
(en)
|
2017-09-12 |
2022-11-15 |
Sumitomo Pharma Oncology, Inc. |
Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
|
SG11202002322TA
(en)
|
2017-09-14 |
2020-04-29 |
Daiichi Sankyo Co Ltd |
Compound having cyclic structure
|
WO2019075367A1
(en)
|
2017-10-13 |
2019-04-18 |
Tolero Pharmaceuticals, Inc. |
PKM2 ACTIVATORS IN COMBINATION WITH OXYGEN REACTIVE SPECIES FOR THE TREATMENT OF CANCER
|
JOP20180094A1
(ar)
|
2017-10-18 |
2019-04-18 |
Hk Inno N Corp |
مركب حلقي غير متجانس كمثبط بروتين كيناز
|
WO2019126136A2
(en)
*
|
2017-12-18 |
2019-06-27 |
Sterngreene, Inc. |
Pyrimidine compounds useful as tyrosine kinase inhibitors
|
JP2021530554A
(ja)
|
2018-07-26 |
2021-11-11 |
スミトモ ダイニッポン ファーマ オンコロジー, インコーポレイテッド |
異常なacvr1発現を伴う疾患を処置するための方法およびそこで使用するためのacvr1阻害剤
|
KR20210137422A
(ko)
|
2018-09-25 |
2021-11-17 |
블랙 다이아몬드 테라퓨틱스, 인코포레이티드 |
티로신 키나아제 억제제로서의 퀴나졸린 유도체, 조성물, 이들의 제조 방법 및 이들의 용도
|
US11034710B2
(en)
|
2018-12-04 |
2021-06-15 |
Sumitomo Dainippon Pharma Oncology, Inc. |
CDK9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
AU2020221247A1
(en)
|
2019-02-12 |
2021-08-05 |
Sumitomo Pharma Oncology, Inc. |
Formulations comprising heterocyclic protein kinase inhibitors
|
US11793802B2
(en)
|
2019-03-20 |
2023-10-24 |
Sumitomo Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (AML) with venetoclax failure
|
EP3941463A1
(de)
|
2019-03-22 |
2022-01-26 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Zusammensetzungen mit pkm2-modulatoren und behandlungsverfahren damit
|
WO2021155006A1
(en)
|
2020-01-31 |
2021-08-05 |
Les Laboratoires Servier Sas |
Inhibitors of cyclin-dependent kinases and uses thereof
|
WO2021179274A1
(en)
*
|
2020-03-13 |
2021-09-16 |
Suzhou Zanrong Pharma Ltd. |
ErbB RECEPTOR INHIBITORS AS ANTI-TUMOR AGENTS
|
KR102234530B1
(ko)
*
|
2020-09-01 |
2021-03-31 |
대한민국 |
신규 톨트라주릴 유도체 및 이를 포함하는 쿠도아충 예방·치료를 위한 약학 조성물
|