ATE461925T1 - Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung - Google Patents

Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung

Info

Publication number
ATE461925T1
ATE461925T1 AT06751667T AT06751667T ATE461925T1 AT E461925 T1 ATE461925 T1 AT E461925T1 AT 06751667 T AT06751667 T AT 06751667T AT 06751667 T AT06751667 T AT 06751667T AT E461925 T1 ATE461925 T1 AT E461925T1
Authority
AT
Austria
Prior art keywords
benzisoxazolepiperidine
compounds
compositions
methods
invention includes
Prior art date
Application number
AT06751667T
Other languages
English (en)
Inventor
James White
Daniel Coughlin
Dale Edgar
Michael Solomon
David Hangauer
Kazumi Shiosaki
Original Assignee
Hypnion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hypnion Inc filed Critical Hypnion Inc
Priority claimed from PCT/US2006/016059 external-priority patent/WO2006116615A1/en
Application granted granted Critical
Publication of ATE461925T1 publication Critical patent/ATE461925T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT06751667T 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung ATE461925T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67520205P 2005-04-26 2005-04-26
PCT/US2006/016059 WO2006116615A1 (en) 2005-04-26 2006-04-26 Benzisoxazole piperazine compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
ATE461925T1 true ATE461925T1 (de) 2010-04-15

Family

ID=36754209

Family Applications (2)

Application Number Title Priority Date Filing Date
AT06751667T ATE461925T1 (de) 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
AT06751665T ATE459621T1 (de) 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06751665T ATE459621T1 (de) 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung

Country Status (15)

Country Link
US (3) US7494998B2 (de)
EP (2) EP1877405B1 (de)
JP (2) JP5049267B2 (de)
CN (1) CN101208314B (de)
AT (2) ATE461925T1 (de)
AU (1) AU2006239302B2 (de)
CA (2) CA2606471C (de)
CY (1) CY1110026T1 (de)
DE (2) DE602006012650D1 (de)
DK (1) DK1877390T3 (de)
ES (2) ES2341127T3 (de)
MX (1) MX2007013352A (de)
PL (1) PL1877390T3 (de)
PT (1) PT1877390E (de)
WO (1) WO2006116614A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0412263B1 (pt) 2003-07-22 2019-10-15 Arena Pharmaceuticals, Inc. Derivados de diaril e aril heteroaril uréia, uso e composição farmacêutica contendo os mesmos, bem como processo para preparação da dita composição
SA05260357B1 (ar) 2004-11-19 2008-09-08 ارينا فارماسيتو تيكالز ، أنك مشتقات 3_فينيل_بيرازول كمعدلات لمستقبل سيروتينين 5_ht2a مفيدة في علاج الاضطرابات المتعلقه به
US7494998B2 (en) * 2005-04-26 2009-02-24 Hypnion, Inc. Benzisoxazole piperazine compounds and methods of use thereof
EP2018371B1 (de) 2006-05-18 2015-03-04 Arena Pharmaceuticals, Inc. Primäramine und derivate davon als modulatoren des 5-ht2a-serotonin-rezeptors zur behandlung damit zusammenhängender erkrankungen
CN102827081A (zh) 2006-05-18 2012-12-19 艾尼纳制药公司 用作5-ht2a 血清素受体调节剂的苯基-吡唑的晶型和其制备方法
EP2027119A2 (de) 2006-05-18 2009-02-25 Arena Pharmaceuticals, Inc. Ether, sekundäre amine und derivate davon als modulatoren des 5-ht2a-serotonin-rezeptors zur behandlung damit zusammenhängender erkrankungen
US7762006B2 (en) * 2006-06-14 2010-07-27 Siestamed, Technologies Medical equipment drying device
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
JP5731120B2 (ja) * 2007-03-19 2015-06-10 インスライン メディカル エルティーディー． 薬剤送達器具
WO2008114220A2 (en) * 2007-03-19 2008-09-25 Insuline Medical Ltd. Device for drug delivery and associated connections thereto
EP2190844B3 (de) 2007-08-15 2013-07-17 Arena Pharmaceuticals, Inc. Imidazo[1,2-a]pyridinderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich für die behandlung von damit in zusammenhang stehenden erkrankungen eignen
EP2231229A1 (de) 2007-12-18 2010-09-29 Insuline Medical Ltd. Wirkstofffreisetzungsvorrichtung mit sensor für geschlossenen kreislauf
WO2009123714A2 (en) 2008-04-02 2009-10-08 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2009126830A2 (en) * 2008-04-09 2009-10-15 Surmodics, Inc. Delivery of nucleic acid complexes from materials including negatively charged groups
SG176464A1 (en) * 2008-05-09 2011-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
CA2741731A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Compositions of a 5-ht2a serotonin receptor modulator useful for the treatment of disorders related thereto
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
MX2011004817A (es) 2008-11-07 2011-07-28 Insuline Medical Ltd Dispositivo y metodo para suministrar farmacos.
WO2010074753A1 (en) 2008-12-23 2010-07-01 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
WO2011075596A1 (en) 2009-12-18 2011-06-23 Arena Pharmaceuticals, Inc. Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto
US8565107B2 (en) 2010-09-24 2013-10-22 Hand Held Products, Inc. Terminal configurable for use within an unknown regulatory domain
EP4119141A1 (de) 2015-06-12 2023-01-18 Axovant Sciences GmbH Nelotanserin zur prophylaxe und behandlung von schlafverhaltensstörungen in der rem-phase
EP3322415A4 (de) 2015-07-15 2019-03-13 Axovant Sciences GmbH Diaryl- und arylheteroaryl-harnstoff-derivate als modulatoren des 5-ht2a-serotoninrezeptors zur prophylaxe und behandlung von halluzinationen im zusammenhang mit einer neurogenerativen erkrankung
GB201810092D0 (en) 2018-06-20 2018-08-08 Ctxt Pty Ltd Compounds
PL4299135T3 (pl) 2019-06-18 2025-11-12 Pfizer Inc. Pochodne benzizoksazolosulfonamidu
KR20220120625A (ko) 2019-12-24 2022-08-30 스미토모 파마 가부시키가이샤 지방족 산 아미드 유도체
JP7655885B2 (ja) * 2021-06-30 2025-04-02 住友ファーマ株式会社 脂肪族酸アミド誘導体を含有する医薬組成物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3331541A (en) * 1965-06-07 1967-07-18 Bell & Howell Co Sprocketless projector
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
FR2654104B1 (fr) 1989-11-07 1992-01-03 Adir Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DK60593D0 (da) 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
FR2742052B1 (fr) 1995-12-12 1998-04-10 Esteve Labor Dr Utilisation des derives 1-(4-(4-aryl (ou heteroaryl)-1-piper azinyl)-buty)-1h-azole pour le traitement de la depression, des troubles obsessifs compulsifs, l'apnee du sommeil, les dysfonctions sexuelles, l'emese et le mal des transports
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
WO1997049698A1 (en) 1996-06-21 1997-12-31 Glaxo Group Limited Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders
DK1057814T3 (da) * 1997-12-25 2005-07-04 Meiji Seika Kaisha Tetrahydrobenzindolderivater
US6605623B1 (en) 1998-12-18 2003-08-12 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6331541B1 (en) 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
EP1632483B1 (de) 2001-02-16 2008-10-29 Aventis Pharmaceuticals Inc. Heterocyclische substituierte carbonyl derivate und ihre verwendung als dopamin d3 rezeptor liganden
GB0117577D0 (en) * 2001-02-16 2001-09-12 Aventis Pharm Prod Inc Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D receptor ligands
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
US7494998B2 (en) * 2005-04-26 2009-02-24 Hypnion, Inc. Benzisoxazole piperazine compounds and methods of use thereof

Also Published As

Publication number Publication date
CY1110026T1 (el) 2015-01-14
MX2007013352A (es) 2008-03-26
WO2006116614A1 (en) 2006-11-02
DK1877390T3 (da) 2010-05-31
JP2008539267A (ja) 2008-11-13
US20080214539A1 (en) 2008-09-04
US20070004752A1 (en) 2007-01-04
CN101208314B (zh) 2010-12-08
US8088778B2 (en) 2012-01-03
US7494998B2 (en) 2009-02-24
CA2606471C (en) 2014-02-11
EP1877405B1 (de) 2010-03-03
JP2008539268A (ja) 2008-11-13
AU2006239302B2 (en) 2011-07-07
CN101208314A (zh) 2008-06-25
ES2341127T3 (es) 2010-06-15
PL1877390T3 (pl) 2010-08-31
ES2340066T3 (es) 2010-05-28
EP1877390B1 (de) 2010-03-24
DE602006013115D1 (de) 2010-05-06
US20090163514A1 (en) 2009-06-25
AU2006239302A1 (en) 2006-11-02
EP1877405A1 (de) 2008-01-16
DE602006012650D1 (de) 2010-04-15
CA2606473C (en) 2013-08-13
US8129410B2 (en) 2012-03-06
CA2606471A1 (en) 2006-11-02
EP1877390A1 (de) 2008-01-16
JP5049267B2 (ja) 2012-10-17
ATE459621T1 (de) 2010-03-15
PT1877390E (pt) 2010-05-31
CA2606473A1 (en) 2006-11-02

Similar Documents

Publication Publication Date Title
ATE459621T1 (de) Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
EP2054058A4 (de) Pyruvatkinasehemmer und verfahren zur behandlung von erkrankungen
CY1109916T1 (el) Βενζιμιδαζολο-θειοφαινικες ενωσεις ως plk αναστολεις
EP1743486A4 (de) Verfahren und vorrichtungen zur minimierung von cokanalstörungen
DE602004004267D1 (de) Formtrennmittelzusammensetzung und verfahren damit
CY1113386T1 (el) Αναστολεις πρωτεασωματος
EP1626730A4 (de) Verfahren, gerät und zusammensetzung zur behandlung von akne
DE602007005256D1 (de) Verbindungen und verfahren zur modulierung von fx-rezeptoren
EP1613592A4 (de) Hydroxansäureverbindungen und verfahren zu deren anwendung
AT9566U3 (de) Kopierfräseinrichtung zur herstellung von zahntechnischen werkstücken
ATE548374T1 (de) 2'-fluor-2'-desoxytetrahydrouridine als cytidindeaminaseinhibitoren
EP1945284A4 (de) Spritzenvorrichtungen, bauteile von spritzenvorrichtungen und verfahren zur ausbildung von bauteilen und spritzenvorrichtungen
DK1879573T3 (da) Modulatorer af indolamin 2,3-dioxygenase og fremgangsmåder til anvendelse deraf
DE602005026984D1 (de) Chinolin-derivate zur behandlung von latenter tuberkulose
EP1799260A4 (de) Antiamyloide antikörper, zusammensetzungen, verfahren und verwendungen
ATE473744T1 (de) Modifizierte pyrimidin-glucocorticoid-rezeptor- modulatoren
DE602005004280D1 (de) Verfahren zum ziehen von sic-einkristallen und sic-einkristall
DE602008006045D1 (de) Heterocyclische verbindungen, zusammensetzungen damit und verfahren zu ihrer anwendung
DE602005024599D1 (de) Verbindungen modulierende thrombopoietinaktivität und verfahren
DE602006017980D1 (de) 3,4-substituierte pyrrolidin-derivate zur behandlung von hypertonie
EP1885393A4 (de) Verfahren und zusammensetzungen zur immunisierung gegen chlamydien-infektionen
EP1877068A4 (de) Nicotinamidribosid-kinase-zusammensetzungen und verfahren zu deren verwendung
DE602006005437D1 (de) Verfahren und Vorrichtung zum Herstellung von Bauteilen
DE602006005208D1 (de) Tonerzusammensetzung und Verfahren
ATE413875T1 (de) Zusammensetzungen enthaltend levetiracetam und verfahren zu deren herstellung.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1877390

Country of ref document: EP