EE04717B1 - Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine - Google Patents

Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine

Info

Publication number
EE04717B1
EE04717B1 EEP200100653A EEP200100653A EE04717B1 EE 04717 B1 EE04717 B1 EE 04717B1 EE P200100653 A EEP200100653 A EE P200100653A EE P200100653 A EEP200100653 A EE P200100653A EE 04717 B1 EE04717 B1 EE 04717B1
Authority
EE
Estonia
Prior art keywords
preparation
composition
indolylpiperidine compounds
indolylpiperidine
compounds
Prior art date
Application number
EEP200100653A
Other languages
English (en)
Inventor
Pages Santacana Lluis
Fonquerna Pou Silvia
Puig Duran Carles
Fernandez Forner Dolors
Original Assignee
Almirall Prodesfarma, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma, S.A. filed Critical Almirall Prodesfarma, S.A.
Publication of EE200100653A publication Critical patent/EE200100653A/et
Publication of EE04717B1 publication Critical patent/EE04717B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200100653A 1999-06-04 2000-05-31 Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine EE04717B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009901232A ES2165274B1 (es) 1999-06-04 1999-06-04 Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
PCT/EP2000/005010 WO2000075130A1 (en) 1999-06-04 2000-05-31 Indolylpiperidine derivatives as antihistaminic and antiallergic agents

Publications (2)

Publication Number Publication Date
EE200100653A EE200100653A (et) 2003-02-17
EE04717B1 true EE04717B1 (et) 2006-10-16

Family

ID=8308707

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100653A EE04717B1 (et) 1999-06-04 2000-05-31 Indolüülpiperidiinühendid, nende valmistamismeetod, kompositsioon ja nende kasutamine

Country Status (35)

Country Link
US (1) US6683096B2 (et)
EP (1) EP1183251B1 (et)
JP (1) JP2003501424A (et)
KR (1) KR100683454B1 (et)
CN (1) CN1191246C (et)
AR (1) AR029640A1 (et)
AT (1) ATE259362T1 (et)
AU (1) AU773164B2 (et)
BG (1) BG106168A (et)
BR (1) BR0011340A (et)
CA (1) CA2375985A1 (et)
CO (1) CO5180556A1 (et)
CZ (1) CZ20014334A3 (et)
DE (1) DE60008239T2 (et)
DK (1) DK1183251T3 (et)
EE (1) EE04717B1 (et)
ES (2) ES2165274B1 (et)
HK (1) HK1040990A1 (et)
HU (1) HUP0203320A3 (et)
IL (1) IL146629A0 (et)
MX (1) MXPA01012425A (et)
MY (1) MY127033A (et)
NO (1) NO20015897D0 (et)
NZ (1) NZ515649A (et)
PE (1) PE20010208A1 (et)
PL (1) PL196774B1 (et)
PT (1) PT1183251E (et)
RU (1) RU2246493C2 (et)
SI (1) SI1183251T1 (et)
SK (1) SK17042001A3 (et)
TR (1) TR200103490T2 (et)
TW (1) TWI226889B (et)
UA (1) UA72517C2 (et)
WO (1) WO2000075130A1 (et)
ZA (1) ZA200109676B (et)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1509285A (zh) * 2000-01-17 2004-06-30 被取代的芳基酮类
ES2172436B1 (es) * 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
AU2002243394A1 (en) * 2000-11-16 2002-06-24 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
ES2201907B1 (es) * 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
BRPI0416665A (pt) 2003-11-17 2007-01-16 Boehringer Ingelheim Int indóis substituìdos com piperidina ou heteroderivados dos mesmos
US20050245540A1 (en) * 2003-12-09 2005-11-03 Fujisawa Pharmaceutical Co., Ltd. New methods
WO2005101838A2 (en) * 2004-04-13 2005-10-27 Incyte Corporation Piperazinylpiperidine derivatives as chemokine receptor antagonists
CA2570637A1 (en) 2004-06-24 2006-02-02 Wenqing Yao N-substituted piperidines and their use as pharmaceuticals
US20060009491A1 (en) * 2004-06-24 2006-01-12 Incyte Corporation Amido compounds and their use as pharmaceuticals
CN101208314B (zh) * 2005-04-26 2010-12-08 海普尼昂公司 苯并异*唑哌嗪化合物及其使用方法
JP5080450B2 (ja) 2005-04-30 2012-11-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規なピペリジン置換インドール
US20060275516A1 (en) * 2005-06-02 2006-12-07 Ram A N S Compositions and methods for the treatment of allergic rhinitis
US20080108586A1 (en) * 2006-09-06 2008-05-08 Incyte Corporation Combination therapy for human immunodeficiency virus infection
ATE537166T1 (de) * 2006-10-27 2011-12-15 Boehringer Ingelheim Int Piperidylpropanthiole als ccr3-modulatoren
JP5550352B2 (ja) 2007-03-15 2014-07-16 ノバルティス アーゲー 有機化合物およびその使用
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
CN101560179B (zh) * 2009-05-25 2012-04-18 浙江大学 具有h3受体亲和能力的含氮吲哚衍生物和用途
CN101747321B (zh) * 2009-12-22 2013-01-02 浙江大学 吲哚-3-苄胺衍生物及制备方法和用途
EP3040334A1 (en) * 2014-12-29 2016-07-06 Faes Farma, S.A. New benzimidazole derivatives as antihistamine agents
MX2024001155A (es) * 2021-07-30 2024-07-01 Confo Therapeutics N V Compuestos para el tratamiento del dolor, en particular el dolor neuropatico, y/u otras enfermedades o trastornos que se asocian con at2r y/o se?alizacion mediada por at2r.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
JPS63301881A (ja) * 1987-06-01 1988-12-08 Fujisawa Pharmaceut Co Ltd インドリルピペリジン誘導体
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8800795D0 (en) * 1988-01-14 1988-02-17 Fujisawa Pharmaceutical Co New indolylpiperidine compounds processes for preparations thereof & pharmaceutical composition comprising same
GB8900382D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
CA2129995C (en) * 1992-02-13 2000-04-11 Albert A. Carr Piperidinyl thiacyclic derivatives
IT1271417B (it) * 1993-10-15 1997-05-28 Erregierre Ind Chim Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono.
DE19500689A1 (de) 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
DE19707628A1 (de) 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
AR028685A1 (es) * 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol

Also Published As

Publication number Publication date
TR200103490T2 (tr) 2002-04-22
RU2246493C2 (ru) 2005-02-20
CA2375985A1 (en) 2000-12-14
ES2211559T3 (es) 2004-07-16
AU5527600A (en) 2000-12-28
BR0011340A (pt) 2002-03-05
PE20010208A1 (es) 2001-03-19
HUP0203320A2 (hu) 2003-02-28
AU773164B2 (en) 2004-05-20
WO2000075130A1 (en) 2000-12-14
PL196774B1 (pl) 2008-01-31
CN1368969A (zh) 2002-09-11
SI1183251T1 (en) 2004-06-30
US6683096B2 (en) 2004-01-27
NO20015897L (no) 2001-12-03
BG106168A (bg) 2002-07-31
PT1183251E (pt) 2004-05-31
ZA200109676B (en) 2003-02-24
DE60008239D1 (de) 2004-03-18
HUP0203320A3 (en) 2004-01-28
JP2003501424A (ja) 2003-01-14
US20020147344A1 (en) 2002-10-10
UA72517C2 (uk) 2005-03-15
PL353164A1 (en) 2003-10-20
ATE259362T1 (de) 2004-02-15
SK17042001A3 (sk) 2002-04-04
ES2165274B1 (es) 2003-04-01
ES2165274A1 (es) 2002-03-01
RU2002100073A (ru) 2004-01-10
HK1040990A1 (zh) 2002-06-28
EP1183251B1 (en) 2004-02-11
EP1183251A1 (en) 2002-03-06
AR029640A1 (es) 2003-07-10
KR100683454B1 (ko) 2007-02-20
MXPA01012425A (es) 2002-06-04
IL146629A0 (en) 2002-07-25
MY127033A (en) 2006-11-30
DE60008239T2 (de) 2004-11-18
NZ515649A (en) 2003-08-29
KR20020020721A (ko) 2002-03-15
NO20015897D0 (no) 2001-12-03
CZ20014334A3 (cs) 2002-03-13
TWI226889B (en) 2005-01-21
CO5180556A1 (es) 2002-07-30
EE200100653A (et) 2003-02-17
DK1183251T3 (da) 2004-06-07
CN1191246C (zh) 2005-03-02

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Legal Events

Date Code Title Description
HD1A Correction of address
KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

MM4A Lapsed by not paying the annual fees

Effective date: 20080531