ATE378075T1 - Biologisch resorbierbare kalzium phosphate zement-zusammensetzungen - Google Patents

Biologisch resorbierbare kalzium phosphate zement-zusammensetzungen

Info

Publication number
ATE378075T1
ATE378075T1 AT97122455T AT97122455T ATE378075T1 AT E378075 T1 ATE378075 T1 AT E378075T1 AT 97122455 T AT97122455 T AT 97122455T AT 97122455 T AT97122455 T AT 97122455T AT E378075 T1 ATE378075 T1 AT E378075T1
Authority
AT
Austria
Prior art keywords
calcium phosphate
cement compositions
phosphate cement
biologically absorbable
absorbable calcium
Prior art date
Application number
AT97122455T
Other languages
English (en)
Inventor
Brent R Constantz
Original Assignee
Norian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norian Corp filed Critical Norian Corp
Application granted granted Critical
Publication of ATE378075T1 publication Critical patent/ATE378075T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/60Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/70Preparations for dentistry comprising inorganic additives
    • A61K6/71Fillers
    • A61K6/74Fillers comprising phosphorus-containing compounds
    • A61K6/75Apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/32Phosphates of magnesium, calcium, strontium, or barium
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/32Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/322Preparation by neutralisation of orthophosphoric acid
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/32Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/327After-treatment
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/455Phosphates containing halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
AT97122455T 1992-10-16 1993-09-24 Biologisch resorbierbare kalzium phosphate zement-zusammensetzungen ATE378075T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/963,481 US5962028A (en) 1988-04-20 1992-10-16 Carbonated hydroxyapatite compositions and uses

Publications (1)

Publication Number Publication Date
ATE378075T1 true ATE378075T1 (de) 2007-11-15

Family

ID=25507302

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97122455T ATE378075T1 (de) 1992-10-16 1993-09-24 Biologisch resorbierbare kalzium phosphate zement-zusammensetzungen
AT93923726T ATE174872T1 (de) 1992-10-16 1993-09-24 Carbonierte hydroxyapatit-zusammensetzungen und ihre verwendungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT93923726T ATE174872T1 (de) 1992-10-16 1993-09-24 Carbonierte hydroxyapatit-zusammensetzungen und ihre verwendungen

Country Status (7)

Country Link
US (4) US5962028A (de)
EP (2) EP0622990B1 (de)
AT (2) ATE378075T1 (de)
DE (2) DE69322765T2 (de)
DK (1) DK0622990T3 (de)
ES (2) ES2128442T3 (de)
WO (1) WO1994008458A1 (de)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962028A (en) * 1988-04-20 1999-10-05 Norian Corporation Carbonated hydroxyapatite compositions and uses
US6169085B1 (en) 1995-03-10 2001-01-02 G. D. Searle & Company Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US5985870A (en) * 1995-03-10 1999-11-16 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US6667307B2 (en) 1997-12-19 2003-12-23 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US5676976A (en) 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
US20020136696A1 (en) * 1995-05-19 2002-09-26 Dosuk D. Lee Orthopedic and dental ceramic implants
US6287341B1 (en) 1995-05-19 2001-09-11 Etex Corporation Orthopedic and dental ceramic implants
US6953594B2 (en) 1996-10-10 2005-10-11 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
US8728536B2 (en) * 1996-10-16 2014-05-20 Etex Corporation Chemotherapeutic composition using nanocrystalline calcium phosphate paste
US7517539B1 (en) * 1996-10-16 2009-04-14 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
US20030032586A1 (en) * 1997-05-15 2003-02-13 David C. Rueger Compositions for morphogen-induced osteogenesis
GB9727049D0 (en) * 1997-12-22 1998-02-18 Abonetics Ltd Method for the preparation of carbonated hydroxyapatite compositions
GB9727048D0 (en) * 1997-12-22 1998-02-18 Abonetics Ltd Process for the preparation of magnesium and carbonate substituted hydroxyapatite
US6736849B2 (en) 1998-03-11 2004-05-18 Depuy Products, Inc. Surface-mineralized spinal implants
US6139585A (en) * 1998-03-11 2000-10-31 Depuy Orthopaedics, Inc. Bioactive ceramic coating and method
MXPA00000009A (es) 1998-06-22 2005-09-08 Autologous Wound Therapy Inc Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas.
DE59903490D1 (de) * 1998-09-11 2003-01-02 Schmidmaier Gerhard Biologisch aktive implantate
GB2349877A (en) * 1999-05-10 2000-11-15 Abonetics Ltd Preparing carbonated hydroxyapatite
CN101347635B (zh) * 1999-12-09 2013-10-16 H.C.罗伯特·马泰斯·斯蒂夫腾 用镁盐稳定的透钙磷石水硬性胶凝材料
US7758882B2 (en) 2000-01-31 2010-07-20 Indiana University Research And Technology Corporation Composite biomaterial including anisometric calcium phosphate reinforcement particles and related methods
US7820191B2 (en) 2000-04-28 2010-10-26 Skeletal Kinetics, Llc Calcium phosphate cements prepared from silicate solutions
US6375935B1 (en) 2000-04-28 2002-04-23 Brent R. Constantz Calcium phosphate cements prepared from silicate solutions
DE10032220A1 (de) * 2000-07-03 2002-01-24 Sanatis Gmbh Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung
AU2002213313B2 (en) * 2000-10-16 2006-08-17 University Of South Carolina Biocompatible cement containing reactive calcium phosphate nanoparticles and methods for making and using such cement
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7709029B2 (en) * 2001-01-24 2010-05-04 Ada Foundation Calcium-containing restoration materials
US6793725B2 (en) * 2001-01-24 2004-09-21 Ada Foundation Premixed calcium phosphate cement pastes
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
FR2830249B1 (fr) 2001-10-03 2004-08-13 Toulouse Inst Nat Polytech Composition de ciment hydraulique a base de carbonates de calcium
US6840961B2 (en) * 2001-12-21 2005-01-11 Etex Corporation Machinable preformed calcium phosphate bone substitute material implants
US7273523B2 (en) 2002-06-07 2007-09-25 Kyphon Inc. Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof
FR2841896B1 (fr) 2002-07-08 2004-10-01 Rousselot Sas Procede de preparation d'un ciment apatitique, ledit ciment ainsi que son utilisation pour pieger les polluants
GB2395713A (en) * 2002-11-13 2004-06-02 Univ Cambridge Tech A synthetic bone material
FR2850282B1 (fr) * 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
TWI367113B (en) 2003-02-12 2012-07-01 Syncera Inc Random and non-random alkylene oxide polymer alloy compositions
EP3254710B1 (de) 2003-04-11 2019-05-22 Etex Corporation Osteoinduktives knochenmaterial
US20040250730A1 (en) * 2003-06-12 2004-12-16 David Delaney Calcium phosphate cements prepared from silicate-phosphate solutions
US20040254668A1 (en) * 2003-06-16 2004-12-16 Jang Bor Z. Macro-porous hydroxyapatite scaffold compositions and freeform fabrication method thereof
US20040250729A1 (en) * 2003-06-16 2004-12-16 Jang Bor Z. Fast-setting carbonated hydroxyapatite compositions and uses
US6867844B2 (en) * 2003-06-19 2005-03-15 Asml Holding N.V. Immersion photolithography system and method using microchannel nozzles
DE602004027730D1 (de) * 2003-06-24 2010-07-29 Univ Kyushu Medizinisches knochenprothesematerial und verfahren zu seiner herstellung
US7306786B2 (en) * 2003-07-28 2007-12-11 Skeletal Kinetics, Llc Calcium phosphate cements comprising a water-soluble contrast agent
EP1663333B1 (de) * 2003-09-05 2018-11-07 Synthes GmbH Knochenzementzusammensetzungen mit faserverstärkung und/oder erhöhter fliessfähigkeit
US7261717B2 (en) * 2003-09-11 2007-08-28 Skeletal Kinetics Llc Methods and devices for delivering orthopedic cements to a target bone site
US7261718B2 (en) * 2003-09-11 2007-08-28 Skeletal Kinetics Llc Use of vibration with polymeric bone cements
CN1878565B (zh) 2003-09-12 2011-01-12 惠氏公司 用于递送成骨蛋白的注射型磷酸钙固体小棒剂和糊剂
US20050220837A1 (en) * 2003-09-30 2005-10-06 Disegi John A Antimicrobial hyaluronic acid coatings for orthopedic implants
US7252833B2 (en) * 2003-11-18 2007-08-07 Skeletal Kinetics, Llc Calcium phosphate cements comprising an osteoclastogenic agent
US8118812B2 (en) 2004-03-09 2012-02-21 Skeletal Kinetics, Llc Use of vibration in composite fixation
US9707024B2 (en) 2004-03-09 2017-07-18 Skeletal Kinetics, Llc Use of vibration in composite fixation
KR101218454B1 (ko) 2004-04-15 2013-01-04 에텍스 코포레이션 세팅 지연 칼슘 포스페이트 페이스트
ES2396133T3 (es) 2004-04-27 2013-02-19 Kyphon SÀRl Composiciones de sustitución osea y método de uso
US7252841B2 (en) * 2004-05-20 2007-08-07 Skeletal Kinetics, Llc Rapid setting calcium phosphate cements
US20050257714A1 (en) * 2004-05-20 2005-11-24 Constantz Brent R Orthopedic cements comprising a barium apatite contrast agent
US7175858B2 (en) * 2004-07-26 2007-02-13 Skeletal Kinetics Llc Calcium phosphate cements and methods for using the same
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060110422A1 (en) * 2004-11-19 2006-05-25 Tas Ahmet C Conversion of calcite powders into macro- and microporous calcium phosphate scaffolds for medical applications
WO2006062518A2 (en) 2004-12-08 2006-06-15 Interpore Spine Ltd. Continuous phase composite for musculoskeletal repair
US7416602B2 (en) * 2005-04-08 2008-08-26 Howmedica Leibinger, Inc. Calcium phosphate cement
US7459018B2 (en) * 2005-04-08 2008-12-02 Howmedica Leibinger Inc. Injectable calcium phosphate cement
US7621963B2 (en) * 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
US20060233849A1 (en) * 2005-04-13 2006-10-19 Simon Bruce J Composite bone graft material
US7651701B2 (en) 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
AU2006304730B2 (en) * 2005-10-21 2012-09-20 Ada Foundation Dual-phase cement precursor systems for bone repair
US9101436B2 (en) * 2005-10-21 2015-08-11 Ada Foundation Dental and endodontic filling materials and methods
US9259439B2 (en) * 2005-10-21 2016-02-16 Ada Foundation Dual-phase cement precursor systems for bone repair
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
US20070185495A1 (en) * 2006-01-30 2007-08-09 Howmedica International S. De R. L. Plug-in syringe stand
CA2641860C (en) 2006-02-09 2015-07-14 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
US7754005B2 (en) 2006-05-02 2010-07-13 Kyphon Sarl Bone cement compositions comprising an indicator agent and related methods thereof
US7507286B2 (en) 2006-06-08 2009-03-24 Sanatis Gmbh Self-foaming cement for void filling and/or delivery systems
JP5484047B2 (ja) 2006-06-30 2014-05-07 バイオミメティック セラピューティクス, エルエルシー 回旋筋腱板傷害を処置するためのpdgf−生体マトリックス組成物および方法
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
AU2007300585A1 (en) * 2006-09-21 2008-04-03 Kyphon Sarl Diammonium phosphate and other ammonium salts and their use in preventing clotting
EP1917924A1 (de) * 2006-11-02 2008-05-07 Stryker Trauma GmbH Implantierungsvorrichtung
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
US20080195223A1 (en) * 2006-11-03 2008-08-14 Avram Allan Eddin Materials and Methods and Systems for Delivering Localized Medical Treatments
US8388626B2 (en) 2006-11-08 2013-03-05 Warsaw Orthopedic, Inc. Methods of employing calcium phosphate cement compositions and osteoinductive proteins to effect vertebrae interbody fusion absent an interbody device
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20080195476A1 (en) * 2007-02-09 2008-08-14 Marchese Michael A Abandonment remarketing system
US20090061002A1 (en) * 2007-09-05 2009-03-05 Venbrocks Rudolf A Calcium phospate based delivery of growth and differentiation factors to compromised bone
CN102014977B (zh) 2008-02-07 2015-09-02 生物模拟治疗有限责任公司 用于牵引成骨术的组合物和方法
US7968616B2 (en) 2008-04-22 2011-06-28 Kyphon Sarl Bone cement composition and method
ES2334623B1 (es) * 2008-05-30 2011-04-08 Jose Luis Jose Chafer Procedimiento para el tratamiento de la caries dental mediante laser,biomaterial para realizarlo y su uso.
JP2009291304A (ja) * 2008-06-03 2009-12-17 Gc Corp 骨補填材
DE102008027389B4 (de) * 2008-06-09 2019-11-14 Atmel Corp. Sendeschaltung und Verfahren zum Senden einer zu übertragenden Bitfolge
US10010500B2 (en) * 2008-08-21 2018-07-03 Biomet Manufacturing, Llc Ceramic implants affording controlled release of active materials
AU2009291828C1 (en) 2008-09-09 2016-03-17 Biomimetic Therapeutics, Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US8673364B2 (en) 2009-09-28 2014-03-18 Skeletal Kinetics, Llc Rapid setting high strength calcium phosphate cements comprising cyclodextrins
US8409538B2 (en) * 2008-12-04 2013-04-02 Skeletal Kinetics Llc Tricalcium phosphate coarse particle compositions and methods for making the same
EP2512537B1 (de) 2009-12-18 2015-08-26 Howmedica Osteonics Corp. Direkt injizierbare knochenzementpräkursorsysteme aus zwei mittels gemachten pasten und verfahren zu ihrer herstellung
PL214929B1 (pl) * 2009-12-28 2013-09-30 Akad Gorniczo Hutnicza Sposób otrzymywania syntetycznego bioceramicznego tworzywa implantacyjnego na bazie hydroksyapatytów weglanowych
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
JP6144049B2 (ja) 2010-02-22 2017-06-07 バイオミメティック セラピューティクス,リミテッド ライアビリティ カンパニー 腱障害を処置するための血小板由来成長因子組成物及び方法
CA2809606C (en) 2010-08-26 2020-12-01 University Of Louisville Research Foundation, Inc. Compositions and methods for treating bone defects
WO2012062360A1 (en) 2010-11-10 2012-05-18 Stryker Trauma Gmbh Polymeric bone foam composition and method
JP2013542837A (ja) 2010-11-15 2013-11-28 ジンマー オーソバイオロジクス,インコーポレイティド 骨空隙充填剤
EP2958603B1 (de) 2013-02-20 2018-03-28 Bone Support AB Verbesserte aushärtung von härtbarem knochenersatz
AU2014331971B2 (en) 2013-10-08 2018-07-19 Vivorte, Inc. Processed bone particle compositions and related methods
US20170252480A1 (en) * 2014-09-01 2017-09-07 Kyushu University, National University Corporation Method of producing product inorganic compound and product inorganic compound
CA3031471A1 (en) 2016-07-25 2018-02-01 Cerapedics, Inc. Peptide-coated calcium phosphate particles
ES2716942B2 (es) * 2018-06-22 2021-03-29 Univ Cardenal Herrera Ceu Composicion y procedimiento para la obtencion y aplicacion de un compuesto bioactivo que contiene fluoruro y el producto obtenido.

Family Cites Families (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US33121A (en) * 1861-08-20 blythe
US33161A (en) * 1861-08-27 Improvement in molds for earthen or cement pipes
US33221A (en) * 1861-09-03 Improvement in soap
US3379541A (en) * 1964-02-18 1968-04-23 Monsanto Co Alkaline earth metal hydroxylapatites, processes for preparing the same and compositions containing the same
US3647371A (en) * 1968-08-07 1972-03-07 Monsanto Co Method for preparation of dicalcium phosphate
US3790507A (en) 1969-03-10 1974-02-05 Research Corp Plastic bone composition
FR2096886B1 (de) * 1970-07-10 1974-04-12 Dentoria
US4139599A (en) * 1973-01-11 1979-02-13 Colgate Palmolive Company Process for preparing dicalcium phosphate dihydrate having a portion of the calcium displaced by divalent metal ion
US4048300A (en) * 1973-01-11 1977-09-13 Colgate-Palmolive Company Dental preparation containing materials having calcium and phosphate components
GB1450157A (en) * 1973-03-06 1976-09-22 Colgate Palmolive Co Dental powder cement and filling material
US3913229A (en) * 1974-02-25 1975-10-21 Miter Inc Dental treatments
AU518908B2 (en) * 1974-08-02 1981-10-29 Sterling Drug Inc. Ceramics
GB1487181A (en) * 1974-10-30 1977-09-28 Colgate Palmolive Co Sintered ceramics
DE2511122B2 (de) 1975-03-14 1977-06-08 Vorprodukt fuer die zubereitung von knochenzement
US4170658A (en) * 1976-01-28 1979-10-09 The Georgia Marble Company Calcium carbonate filler
SE414399B (sv) * 1976-03-16 1980-07-28 Hans Scheicher Keramiskt material for anvendning inom medicinen, i synnerhet for framstellning av implantat, fremst odontologiska implantat samt sett for framstellning av materialet
US4097935A (en) * 1976-07-21 1978-07-04 Sterling Drug Inc. Hydroxylapatite ceramic
JPS5951485B2 (ja) * 1977-03-11 1984-12-14 東京医科歯科大学長 CaO−P↓2O↓5系アパタイトの製造法
DE2808425A1 (de) * 1978-02-27 1979-08-30 Pluss Stauffer Ag Mineralischer fuellstoff
DE2862446D1 (en) 1978-06-29 1984-11-15 Osteo Ag Carbon fiber reinforced bone cement
GB2025912A (en) * 1978-07-21 1980-01-30 Spencer M Process for preparing a crystalline form of calcium phosphate
JPS5645814A (en) * 1979-09-25 1981-04-25 Kureha Chem Ind Co Ltd Hydroxyapatite, its ceramic material and its manufacture
JPS5654841A (en) 1979-10-08 1981-05-15 Mitsubishi Mining & Cement Co Bone broken portion and filler for void portion and method of treating bone of animal using said filler
USRE33121E (en) 1980-05-08 1989-11-28 Idacon, Inc. Method and composition for treating wood with pentachlorophenol
JPS5925006B2 (ja) * 1980-10-21 1984-06-13 新日本製鐵株式会社 梯形レンガを用いた転炉築造法
US4324772A (en) * 1980-11-19 1982-04-13 Monsanto Company Process for producing hydroxyapatite
JPS5889288A (ja) * 1981-11-19 1983-05-27 オムロン株式会社 電子パズル
DE3211433C2 (de) * 1982-03-27 1984-12-13 Degussa Ag, 6000 Frankfurt Kristallines Alumosilikat PZ 1 und Verfahren zu seiner Herstellung
USRE33161E (en) 1982-04-29 1990-02-06 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
USRE33221E (en) 1982-04-29 1990-05-22 American Dental Association Health Foundation Dental restorative cement pastes
US4518430A (en) * 1982-04-29 1985-05-21 American Dental Association Health Foundation Dental resptorative cement pastes
JPS5956676A (ja) * 1982-09-25 1984-04-02 松下冷機株式会社 冷蔵庫等の冷却装置
US4673355A (en) * 1982-10-25 1987-06-16 Farris Edward T Solid calcium phosphate materials
GB2132991B (en) * 1982-12-14 1987-03-18 Mitsui Toatsu Chemicals Process for preparing apatite
GB8303188D0 (en) * 1983-02-04 1983-03-09 Thackray C F Ltd Acetabular prostheses
US4612053A (en) * 1983-10-06 1986-09-16 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
US4722948A (en) 1984-03-16 1988-02-02 Dynatech Corporation Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone
DE3433210C1 (de) * 1984-09-10 1986-06-05 Hans Dr.med. Dr.med.dent. 8000 München Scheicher Mittel zur Fuellung von Knochen- und Zahndefekten,zum Knochenaufbau,fuer Knochenkontaktschichten und fuer Knochen- und Zahnwurzelersatz und Verwendung von Carbonatapatit fuer diesen Zweck
US4637931A (en) 1984-10-09 1987-01-20 The United States Of America As Represented By The Secretary Of The Army Polyactic-polyglycolic acid copolymer combined with decalcified freeze-dried bone for use as a bone repair material
US4595713A (en) 1985-01-22 1986-06-17 Hexcel Corporation Medical putty for tissue augmentation
US5246457A (en) 1985-03-28 1993-09-21 Collagen Corporation Xenogeneic collagen/mineral preparations in bone repair
US4668295A (en) 1985-04-25 1987-05-26 University Of Dayton Surgical cements
GB8514055D0 (en) 1985-06-04 1985-07-10 Geistlich Soehne Ag Chemical substance
JPS624637A (ja) * 1985-06-28 1987-01-10 Jidosha Denki Kogyo Co Ltd 車速自動制御装置
US4645503A (en) 1985-08-27 1987-02-24 Orthomatrix Inc. Moldable bone-implant material
JPS62182146A (ja) * 1985-10-11 1987-08-10 三井東圧化学株式会社 硬化性材料
JPH0695784B2 (ja) * 1986-02-20 1994-11-24 松下電工株式会社 遠隔監視制御装置の操作用端末器
JPS63252913A (ja) * 1987-04-10 1988-10-20 Mitsui Toatsu Chem Inc 硬化性材料
JPS6474591A (en) * 1987-09-17 1989-03-20 Ricoh Kk Multiwindow display device
JPH0644423B2 (ja) * 1987-11-17 1994-06-08 矢崎総業株式会社 ワイヤーハーネスの製造方法
US5180426A (en) * 1987-12-28 1993-01-19 Asahi Kogaku Kogyo K.K. Composition for forming calcium phosphate type setting material and process for producing setting material
JPH01203801A (ja) * 1988-02-09 1989-08-16 Ube Ind Ltd 垂直伝熱管を有した流動床ボイラおよび該ボイラを用いた流動床温水ボイラ
JP2678912B2 (ja) * 1988-04-14 1997-11-19 日本フィルコン株式会社 自動綾分装置及び綾分方法
US4880610A (en) * 1988-04-20 1989-11-14 Norian Corporation In situ calcium phosphate minerals--method and composition
US5053212A (en) * 1988-04-20 1991-10-01 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
US5178845A (en) * 1988-04-20 1993-01-12 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
US5962028A (en) * 1988-04-20 1999-10-05 Norian Corporation Carbonated hydroxyapatite compositions and uses
US5129905A (en) * 1988-04-20 1992-07-14 Norian Corporation Methods for in situ prepared calcium phosphate minerals
US6002065A (en) 1988-04-20 1999-12-14 Norian Corporation Kits for preparing calcium phosphate minerals
US5047031A (en) * 1988-04-20 1991-09-10 Norian Corporation In situ calcium phosphate minerals method
US6005162A (en) 1988-04-20 1999-12-21 Norian Corporation Methods of repairing bone
JP2768949B2 (ja) * 1988-06-08 1998-06-25 三菱電機株式会社 半導体装置,及びその製造方法
JPH0773602B2 (ja) * 1988-07-23 1995-08-09 新田ゼラチン株式会社 医科用および歯科用硬化性材料
JPH02117444A (ja) * 1988-10-25 1990-05-01 Honda Motor Co Ltd エンジン制御装置
US4863974A (en) 1988-08-03 1989-09-05 W. L. Gore & Associates, Inc. Bone growth matrix and process for making it
US5573771A (en) 1988-08-19 1996-11-12 Osteomedical Limited Medicinal bone mineral products
US5009898A (en) * 1988-09-29 1991-04-23 Kabushiki Kaisha Sangi Antimicrobial hydroxyapatite powders and methods for preparing them
JPH02117445A (ja) * 1988-10-25 1990-05-01 Isuzu Motors Ltd サスペンション装置付きシート
US5034059A (en) 1989-02-17 1991-07-23 Norian Corporation Composition comprising octacalcium phosphate crystals and polypeptide
JP2754689B2 (ja) * 1989-03-28 1998-05-20 東レ株式会社 トリプトファナーゼ生産能を有する形質転換体およびl―トリプトファンの製造法
JPH0645487B2 (ja) * 1989-05-19 1994-06-15 徳山曹達株式会社 硬化材
US5073373A (en) 1989-09-21 1991-12-17 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
JPH03123609A (ja) * 1989-10-06 1991-05-27 Matsushita Electric Ind Co Ltd 浴槽水の循環装置
CA2027921C (en) 1989-10-19 1997-12-09 Nobuo Nakabayashi Bone cement composition, cured product thereof, implant material and process for the preparation of the same
US5322675A (en) * 1990-11-09 1994-06-21 Director-General Of Agency Of Industrial Science And Technology Method of preparing calcium phosphate
JPH03174349A (ja) * 1989-12-01 1991-07-29 Mitsubishi Materials Corp 水硬性リン酸カルシウムセメント
JPH03283213A (ja) * 1990-03-29 1991-12-13 Tokyo Electric Co Ltd ハンディターミナル
US5164187A (en) 1990-04-05 1992-11-17 Norian Corporation Hydroxyapatite prosthesis coatings
US5188670A (en) 1990-04-05 1993-02-23 Norian Corporation Apparatus for hydroxyapatite coatings of substrates
JP2657847B2 (ja) 1990-05-10 1997-09-30 寅雄 大塚 水酸化アパタイト多孔質生体充▲てん▼材並びにその製造方法
US5266248A (en) 1990-05-10 1993-11-30 Torao Ohtsuka Method of producing hydroxylapatite base porous beads filler for an organism
EP0541687B1 (de) * 1990-07-27 1997-08-27 Norian Corporation Innige mischung von galcium- und phosphat-quellen als hydroxyapatit-vorläufer
DE4124898A1 (de) * 1990-07-27 1992-01-30 Osaka Cement Mit apatit ueberzogene tetracalciumphosphat-teilchen
JP2621622B2 (ja) * 1990-09-27 1997-06-18 三菱マテリアル株式会社 水硬性リン酸カルシウムセメント
US5231169A (en) 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5149368A (en) * 1991-01-10 1992-09-22 Liu Sung Tsuen Resorbable bioactive calcium phosphate cement
US5262166A (en) * 1991-04-17 1993-11-16 Lty Medical Inc Resorbable bioactive phosphate containing cements
JP3000718B2 (ja) * 1991-05-28 2000-01-17 三菱マテリアル株式会社 薬物徐放性リン酸カルシウムセメント
JP3000719B2 (ja) * 1991-05-28 2000-01-17 三菱マテリアル株式会社 水硬性リン酸カルシウムセメント
US5782971B1 (en) * 1991-06-28 1999-09-21 Norian Corp Calcium phosphate cements comprising amorophous calcium phosphate
JPH059383A (ja) * 1991-06-29 1993-01-19 Dainippon Ink & Chem Inc ポリアリーレンサルフアイド樹脂組成物
JPH0523386A (ja) * 1991-07-23 1993-02-02 Mitsubishi Materials Corp リン酸カルシウムセメント
JP2686684B2 (ja) 1991-08-27 1997-12-08 寅雄 大塚 水酸化アパタイトを充填し生体内溶解性繊維により編機されたチューブ網編成物
US5338356A (en) * 1991-10-29 1994-08-16 Mitsubishi Materials Corporation Calcium phosphate granular cement and method for producing same
ES2040626B1 (es) * 1991-11-22 1994-05-16 Boltong Maria G Procedimiento para la obtencion de cementos de fosfatos de calcio y su empleo como biomteriales.
US5769897A (en) 1991-12-13 1998-06-23 Haerle; Anton Synthetic bone
EP0573491B1 (de) * 1991-12-30 2002-04-03 Norian Corporation Mineralisiertes kollagen
US5314476A (en) 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
US5366507A (en) 1992-03-06 1994-11-22 Sottosanti John S Method for use in bone tissue regeneration
US5320844A (en) * 1992-03-12 1994-06-14 Liu Sung Tsuen Composite materials for hard tissue replacement
JPH05319891A (ja) * 1992-05-19 1993-12-03 Mitsubishi Materials Corp 球状α型第3リン酸カルシウム及び水硬性リン酸カルシウムセメント組成物
FR2693716B1 (fr) * 1992-07-20 1994-10-21 Toulouse Inst Nat Polytech Procédé d'obtention d'hydroxyapatite phosphocalcique, applications au comblement osseux ou dentaire, ou au moulage de pièces, et produits utilisés.
JPH0645494A (ja) * 1992-07-22 1994-02-18 Nec Corp 半導体集積回路用パッケージ
US5565502A (en) 1993-03-24 1996-10-15 Children's Medical Center Corporation Isolation of the calcium-phosphate crystals of bone
US5439951A (en) 1993-03-24 1995-08-08 Children's Medical Center Corporation Isolation of the calcium-phosphate crystals of bone
GB9310321D0 (en) * 1993-05-19 1993-06-30 Queen Mary & Westfield College Method for the preparation of carbonated hydroxyapatite compositions
JP3773254B2 (ja) * 1993-07-22 2006-05-10 ノリアン コーポレイション 貯蔵安定性の部分中和化酸組成物及び利用
US5531791A (en) 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
EP0639366A1 (de) * 1993-08-19 1995-02-22 Kingstar Technology Limited (Uk) Hydroxylapatit Zement als Zahn- oder Knochenersatz
US6201039B1 (en) * 1993-09-21 2001-03-13 The Penn State Research Foundation Bone substitute composition comprising hydroxyapatite and a method of production therefor
US5525148A (en) * 1993-09-24 1996-06-11 American Dental Association Health Foundation Self-setting calcium phosphate cements and methods for preparing and using them
FR2715853B1 (fr) 1994-02-08 1996-04-26 Centre Nat Rech Scient Composition pour bio-matériau; procédé de préparation.
CA2143733A1 (en) * 1994-03-02 1995-09-03 Yoshikazu Umezu Alpha-tricalcium phosphate ceramic and production method thereof
US5626861A (en) 1994-04-01 1997-05-06 Massachusetts Institute Of Technology Polymeric-hydroxyapatite bone composite
US5496399A (en) * 1994-08-23 1996-03-05 Norian Corporation Storage stable calcium phosphate cements
US5707962A (en) 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof
US5569442A (en) 1994-11-04 1996-10-29 Norian Corporation Reactive tricalcium phosphate compositions and uses
WO1996029144A1 (en) * 1995-03-20 1996-09-26 The Penn State Research Foundation Hydroxyapatite forming dry particulate agglomerate and methods therefor
US5676976A (en) 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US5788976A (en) 1996-02-12 1998-08-04 Wbk, Inc. Method for effecting bone repair
CA2260894C (en) 1996-08-06 2005-04-12 Steven Michael Schein Electronic program guide with interactive areas
US6037519A (en) 1997-10-20 2000-03-14 Sdgi Holdings, Inc. Ceramic fusion implants and compositions
US5866155A (en) 1996-11-20 1999-02-02 Allegheny Health, Education And Research Foundation Methods for using microsphere polymers in bone replacement matrices and composition produced thereby
CN1244815A (zh) 1996-12-13 2000-02-16 诺瑞安有限公司 胶结剂的制备、存放和处理
US5972368A (en) 1997-06-11 1999-10-26 Sdgi Holdings, Inc. Bone graft composites and spacers
US5910315A (en) 1997-07-18 1999-06-08 Stevenson; Sharon Allograft tissue material for filling spinal fusion cages or related surgical spaces
US5968999A (en) 1997-10-28 1999-10-19 Charlotte-Mecklenburg Hospital Authority Bone cement compositions
US6030635A (en) 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US5968253A (en) 1998-07-31 1999-10-19 Norian Corporation Calcium phosphate cements comprising antimicrobial agents

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ES2297845T3 (es) 2008-05-01
DE69334185D1 (de) 2007-12-27
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US5962028A (en) 1999-10-05
US6334891B1 (en) 2002-01-01
DE69322765T2 (de) 1999-06-17
DE69334185T2 (de) 2008-10-16
DE69322765D1 (de) 1999-02-04
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