DE69334185D1 - Biologisch resorbierbare Kalzium Phosphate Zement- Zusammensetzungen - Google Patents

Biologisch resorbierbare Kalzium Phosphate Zement- Zusammensetzungen

Info

Publication number
DE69334185D1
DE69334185D1 DE69334185T DE69334185T DE69334185D1 DE 69334185 D1 DE69334185 D1 DE 69334185D1 DE 69334185 T DE69334185 T DE 69334185T DE 69334185 T DE69334185 T DE 69334185T DE 69334185 D1 DE69334185 D1 DE 69334185D1
Authority
DE
Germany
Prior art keywords
calcium phosphate
cement compositions
phosphate cement
bioresorbable calcium
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69334185T
Other languages
English (en)
Other versions
DE69334185T2 (de
Inventor
Brent R Constantz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norian Corp
Original Assignee
Norian Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norian Corp filed Critical Norian Corp
Publication of DE69334185D1 publication Critical patent/DE69334185D1/de
Application granted granted Critical
Publication of DE69334185T2 publication Critical patent/DE69334185T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/60Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/70Preparations for dentistry comprising inorganic additives
    • A61K6/71Fillers
    • A61K6/74Fillers comprising phosphorus-containing compounds
    • A61K6/75Apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/32Phosphates of magnesium, calcium, strontium, or barium
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/32Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/322Preparation by neutralisation of orthophosphoric acid
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/32Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/327After-treatment
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00Phosphorus; Compounds thereof
    • C01B25/16Oxyacids of phosphorus; Salts thereof
    • C01B25/26Phosphates
    • C01B25/455Phosphates containing halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Environmental & Geological Engineering (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69334185T 1992-10-16 1993-09-24 Biologisch resorbierbare Kalzium Phosphate Zement- Zusammensetzungen Expired - Lifetime DE69334185T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US963481 1992-10-16
US07/963,481 US5962028A (en) 1988-04-20 1992-10-16 Carbonated hydroxyapatite compositions and uses

Publications (2)

Publication Number Publication Date
DE69334185D1 true DE69334185D1 (de) 2007-12-27
DE69334185T2 DE69334185T2 (de) 2008-10-16

Family

ID=25507302

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69322765T Expired - Lifetime DE69322765T2 (de) 1992-10-16 1993-09-24 Carbonierte hydroxyapatit-zusammensetzungen und ihre verwendungen
DE69334185T Expired - Lifetime DE69334185T2 (de) 1992-10-16 1993-09-24 Biologisch resorbierbare Kalzium Phosphate Zement- Zusammensetzungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69322765T Expired - Lifetime DE69322765T2 (de) 1992-10-16 1993-09-24 Carbonierte hydroxyapatit-zusammensetzungen und ihre verwendungen

Country Status (7)

Country Link
US (4) US5962028A (de)
EP (2) EP0835668B1 (de)
AT (2) ATE378075T1 (de)
DE (2) DE69322765T2 (de)
DK (1) DK0622990T3 (de)
ES (2) ES2128442T3 (de)
WO (1) WO1994008458A1 (de)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962028A (en) * 1988-04-20 1999-10-05 Norian Corporation Carbonated hydroxyapatite compositions and uses
US5985870A (en) * 1995-03-10 1999-11-16 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US6169085B1 (en) 1995-03-10 2001-01-02 G. D. Searle & Company Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US6667307B2 (en) 1997-12-19 2003-12-23 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
US20020136696A1 (en) * 1995-05-19 2002-09-26 Dosuk D. Lee Orthopedic and dental ceramic implants
US6287341B1 (en) 1995-05-19 2001-09-11 Etex Corporation Orthopedic and dental ceramic implants
US5676976A (en) 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
US6953594B2 (en) 1996-10-10 2005-10-11 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
US7517539B1 (en) * 1996-10-16 2009-04-14 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
US8728536B2 (en) * 1996-10-16 2014-05-20 Etex Corporation Chemotherapeutic composition using nanocrystalline calcium phosphate paste
US20030032586A1 (en) * 1997-05-15 2003-02-13 David C. Rueger Compositions for morphogen-induced osteogenesis
GB9727049D0 (en) * 1997-12-22 1998-02-18 Abonetics Ltd Method for the preparation of carbonated hydroxyapatite compositions
GB9727048D0 (en) * 1997-12-22 1998-02-18 Abonetics Ltd Process for the preparation of magnesium and carbonate substituted hydroxyapatite
US6736849B2 (en) 1998-03-11 2004-05-18 Depuy Products, Inc. Surface-mineralized spinal implants
US6139585A (en) 1998-03-11 2000-10-31 Depuy Orthopaedics, Inc. Bioactive ceramic coating and method
AU2763099A (en) 1998-06-22 2000-01-10 Charles E. Worden Enriched platelet wound healant
CA2350638C (en) 1998-09-11 2009-11-24 Gerhard Schmidmaier Biologically active implants coated with a biodegradable polymer
GB2349877A (en) * 1999-05-10 2000-11-15 Abonetics Ltd Preparing carbonated hydroxyapatite
ES2204198T3 (es) * 1999-12-09 2004-04-16 Dr.H.C. Robert Mathys Stiftung Cemento hidraulico de brushita estabilizado con una sal de magnesio.
AU2001231264A1 (en) * 2000-01-31 2001-08-07 Advanced Research And Technology Institute, Inc. Composite biomaterial including anisometric calcium phosphate reinforcement particles and related methods
US7820191B2 (en) 2000-04-28 2010-10-26 Skeletal Kinetics, Llc Calcium phosphate cements prepared from silicate solutions
US6375935B1 (en) 2000-04-28 2002-04-23 Brent R. Constantz Calcium phosphate cements prepared from silicate solutions
DE10032220A1 (de) 2000-07-03 2002-01-24 Sanatis Gmbh Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung
EP1335887A4 (de) * 2000-10-16 2004-06-23 Univ South Carolina Biokompatibler zement mit reaktiven calciumphosphat-nanoteilchen und verfahren zur herstellung und verwendung eines derartigen zements
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7709029B2 (en) * 2001-01-24 2010-05-04 Ada Foundation Calcium-containing restoration materials
US6793725B2 (en) 2001-01-24 2004-09-21 Ada Foundation Premixed calcium phosphate cement pastes
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
FR2830249B1 (fr) 2001-10-03 2004-08-13 Toulouse Inst Nat Polytech Composition de ciment hydraulique a base de carbonates de calcium
US6840961B2 (en) * 2001-12-21 2005-01-11 Etex Corporation Machinable preformed calcium phosphate bone substitute material implants
US7273523B2 (en) 2002-06-07 2007-09-25 Kyphon Inc. Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof
FR2841896B1 (fr) 2002-07-08 2004-10-01 Rousselot Sas Procede de preparation d'un ciment apatitique, ledit ciment ainsi que son utilisation pour pieger les polluants
GB2395713A (en) * 2002-11-13 2004-06-02 Univ Cambridge Tech A synthetic bone material
FR2850282B1 (fr) * 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
AU2004211991B2 (en) 2003-02-12 2011-03-31 Syncera, Inc. Random and non-random alkylene oxide polymer alloy compositions
JP5189763B2 (ja) 2003-04-11 2013-04-24 エテックス コーポレーション 骨誘導性骨材料
US20040250730A1 (en) * 2003-06-12 2004-12-16 David Delaney Calcium phosphate cements prepared from silicate-phosphate solutions
US20040254668A1 (en) * 2003-06-16 2004-12-16 Jang Bor Z. Macro-porous hydroxyapatite scaffold compositions and freeform fabrication method thereof
US20040250729A1 (en) * 2003-06-16 2004-12-16 Jang Bor Z. Fast-setting carbonated hydroxyapatite compositions and uses
US6867844B2 (en) * 2003-06-19 2005-03-15 Asml Holding N.V. Immersion photolithography system and method using microchannel nozzles
WO2004112856A1 (ja) * 2003-06-24 2004-12-29 Kyushu Tlo Company Limited 医療用骨補填材およびその製造方法
US7306786B2 (en) * 2003-07-28 2007-12-11 Skeletal Kinetics, Llc Calcium phosphate cements comprising a water-soluble contrast agent
AU2004273794A1 (en) * 2003-09-05 2005-03-31 Norian Corporation Bone cement compositions having fiber-reinforcement and/or increased flowability
US7261717B2 (en) * 2003-09-11 2007-08-28 Skeletal Kinetics Llc Methods and devices for delivering orthopedic cements to a target bone site
US7261718B2 (en) * 2003-09-11 2007-08-28 Skeletal Kinetics Llc Use of vibration with polymeric bone cements
PL1675608T3 (pl) 2003-09-12 2007-11-30 Wyeth Corp Stałe fosforanowo wapniowe pałeczki do wstrzyknięć dla dostarczania białek osteogennych
CA2540714A1 (en) * 2003-09-30 2005-04-14 Synthes (Usa) Antimicrobial hyaluronic acid coatings for orthopedic implants
US7252833B2 (en) * 2003-11-18 2007-08-07 Skeletal Kinetics, Llc Calcium phosphate cements comprising an osteoclastogenic agent
US9707024B2 (en) 2004-03-09 2017-07-18 Skeletal Kinetics, Llc Use of vibration in composite fixation
US8118812B2 (en) 2004-03-09 2012-02-21 Skeletal Kinetics, Llc Use of vibration in composite fixation
WO2005117919A2 (en) 2004-04-15 2005-12-15 Etex Corporation Delayed-setting calcium phosphate pastes
JP2007534449A (ja) 2004-04-27 2007-11-29 カイフォン インコーポレイテッド 骨代替組成物および使用方法
US7252841B2 (en) * 2004-05-20 2007-08-07 Skeletal Kinetics, Llc Rapid setting calcium phosphate cements
US20050257714A1 (en) * 2004-05-20 2005-11-24 Constantz Brent R Orthopedic cements comprising a barium apatite contrast agent
US7175858B2 (en) * 2004-07-26 2007-02-13 Skeletal Kinetics Llc Calcium phosphate cements and methods for using the same
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060110422A1 (en) * 2004-11-19 2006-05-25 Tas Ahmet C Conversion of calcite powders into macro- and microporous calcium phosphate scaffolds for medical applications
WO2006062518A2 (en) 2004-12-08 2006-06-15 Interpore Spine Ltd. Continuous phase composite for musculoskeletal repair
US7459018B2 (en) * 2005-04-08 2008-12-02 Howmedica Leibinger Inc. Injectable calcium phosphate cement
US7416602B2 (en) * 2005-04-08 2008-08-26 Howmedica Leibinger, Inc. Calcium phosphate cement
US20060233849A1 (en) * 2005-04-13 2006-10-19 Simon Bruce J Composite bone graft material
US7621963B2 (en) * 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
US7651701B2 (en) 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
EP1945233B1 (de) * 2005-10-21 2017-03-29 Ada Foundation Doppelphasen-zement-vorläufersysteme zur knochenreparatur
US9259439B2 (en) * 2005-10-21 2016-02-16 Ada Foundation Dual-phase cement precursor systems for bone repair
US9101436B2 (en) * 2005-10-21 2015-08-11 Ada Foundation Dental and endodontic filling materials and methods
NZ571113A (en) 2005-11-17 2012-02-24 Biomimetic Therapeutics Inc Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
US20070185495A1 (en) * 2006-01-30 2007-08-09 Howmedica International S. De R. L. Plug-in syringe stand
EP2311505B1 (de) 2006-02-09 2013-11-06 BioMimetic Therapeutics, LLC Zusammensetzungen und Verfahren zur Behandlung von Knochen
US7754005B2 (en) 2006-05-02 2010-07-13 Kyphon Sarl Bone cement compositions comprising an indicator agent and related methods thereof
US7507286B2 (en) 2006-06-08 2009-03-24 Sanatis Gmbh Self-foaming cement for void filling and/or delivery systems
AU2007269712B2 (en) 2006-06-30 2013-02-07 Biomimetic Therapeutics, Llc PDGF-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
AU2007300585A1 (en) * 2006-09-21 2008-04-03 Kyphon Sarl Diammonium phosphate and other ammonium salts and their use in preventing clotting
EP1917924A1 (de) * 2006-11-02 2008-05-07 Stryker Trauma GmbH Implantierungsvorrichtung
WO2008073190A2 (en) * 2006-11-03 2008-06-19 Kyphon Sarl Materials and methods and systems for delivering localized medical treatments
EP2462895B1 (de) 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Zusammensetzungen und Verfahren für Behandlungen von Arthodese
US8388626B2 (en) 2006-11-08 2013-03-05 Warsaw Orthopedic, Inc. Methods of employing calcium phosphate cement compositions and osteoinductive proteins to effect vertebrae interbody fusion absent an interbody device
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20080195476A1 (en) * 2007-02-09 2008-08-14 Marchese Michael A Abandonment remarketing system
US20090061002A1 (en) 2007-09-05 2009-03-05 Venbrocks Rudolf A Calcium phospate based delivery of growth and differentiation factors to compromised bone
JP5864106B2 (ja) 2008-02-07 2016-02-17 バイオミメティック セラピューティクス, エルエルシー 仮骨延長のための組成物および方法
US7968616B2 (en) 2008-04-22 2011-06-28 Kyphon Sarl Bone cement composition and method
ES2334623B1 (es) * 2008-05-30 2011-04-08 Jose Luis Jose Chafer Procedimiento para el tratamiento de la caries dental mediante laser,biomaterial para realizarlo y su uso.
JP2009291304A (ja) * 2008-06-03 2009-12-17 Gc Corp 骨補填材
DE102008027389B4 (de) * 2008-06-09 2019-11-14 Atmel Corp. Sendeschaltung und Verfahren zum Senden einer zu übertragenden Bitfolge
US10010500B2 (en) * 2008-08-21 2018-07-03 Biomet Manufacturing, Llc Ceramic implants affording controlled release of active materials
NZ602861A (en) 2008-09-09 2014-03-28 Biomimetic Therapeutics Llc Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US8409538B2 (en) 2008-12-04 2013-04-02 Skeletal Kinetics Llc Tricalcium phosphate coarse particle compositions and methods for making the same
US8673364B2 (en) * 2009-09-28 2014-03-18 Skeletal Kinetics, Llc Rapid setting high strength calcium phosphate cements comprising cyclodextrins
EP2512537B1 (de) 2009-12-18 2015-08-26 Howmedica Osteonics Corp. Direkt injizierbare knochenzementpräkursorsysteme aus zwei mittels gemachten pasten und verfahren zu ihrer herstellung
PL214929B1 (pl) * 2009-12-28 2013-09-30 Akad Gorniczo Hutnicza Sposób otrzymywania syntetycznego bioceramicznego tworzywa implantacyjnego na bazie hydroksyapatytów weglanowych
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
AU2011217784B2 (en) 2010-02-22 2014-10-09 Biomimetic Therapeutics, Llc. Platelet-derived growth factor compositions and methods for the treatment of tendinopathies
EP2608778B1 (de) 2010-08-26 2017-11-01 University of Louisville Research Foundation, Inc. Zusammensetzungen und verfahren zur behandlung von knochendefekten
US10182973B2 (en) 2010-11-10 2019-01-22 Stryker European Holdings I, Llc Polymeric bone foam composition and method
CN103313733A (zh) 2010-11-15 2013-09-18 捷迈整形外科生物材料有限公司 骨空隙填充剂
PT2958603T (pt) 2013-02-20 2018-06-06 Bone Support Ab Endurecimento melhorado de substituto ósseo endurecível
CA2926421C (en) 2013-10-08 2022-05-03 Vivorte, Inc. Processed bone particle compositions and related methods
JP6663608B2 (ja) * 2014-09-01 2020-03-13 国立大学法人九州大学 骨欠損再建治療用キット、医療用硬組織再建材、製品無機化合物の製造方法及び製品無機化合物
US20210244857A1 (en) 2016-07-25 2021-08-12 Cerapedics, Inc. Peptide-coated calcium phosphate particles
ES2716942B2 (es) * 2018-06-22 2021-03-29 Univ Cardenal Herrera Ceu Composicion y procedimiento para la obtencion y aplicacion de un compuesto bioactivo que contiene fluoruro y el producto obtenido.
CN117923447B (zh) * 2024-03-20 2024-06-04 云南磷化集团有限公司 一种串级式反应釜连续生产磷酸氢钙的方法及其装置

Family Cites Families (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US33121A (en) * 1861-08-20 blythe
US33161A (en) * 1861-08-27 Improvement in molds for earthen or cement pipes
US33221A (en) * 1861-09-03 Improvement in soap
US3379541A (en) * 1964-02-18 1968-04-23 Monsanto Co Alkaline earth metal hydroxylapatites, processes for preparing the same and compositions containing the same
US3647371A (en) * 1968-08-07 1972-03-07 Monsanto Co Method for preparation of dicalcium phosphate
US3790507A (en) 1969-03-10 1974-02-05 Research Corp Plastic bone composition
FR2096886B1 (de) * 1970-07-10 1974-04-12 Dentoria
US4139599A (en) * 1973-01-11 1979-02-13 Colgate Palmolive Company Process for preparing dicalcium phosphate dihydrate having a portion of the calcium displaced by divalent metal ion
US4048300A (en) * 1973-01-11 1977-09-13 Colgate-Palmolive Company Dental preparation containing materials having calcium and phosphate components
GB1450157A (en) * 1973-03-06 1976-09-22 Colgate Palmolive Co Dental powder cement and filling material
US3913229A (en) * 1974-02-25 1975-10-21 Miter Inc Dental treatments
AU518908B2 (en) * 1974-08-02 1981-10-29 Sterling Drug Inc. Ceramics
GB1487181A (en) * 1974-10-30 1977-09-28 Colgate Palmolive Co Sintered ceramics
DE2511122B2 (de) 1975-03-14 1977-06-08 Vorprodukt fuer die zubereitung von knochenzement
US4170658A (en) * 1976-01-28 1979-10-09 The Georgia Marble Company Calcium carbonate filler
SE414399B (sv) * 1976-03-16 1980-07-28 Hans Scheicher Keramiskt material for anvendning inom medicinen, i synnerhet for framstellning av implantat, fremst odontologiska implantat samt sett for framstellning av materialet
US4097935A (en) * 1976-07-21 1978-07-04 Sterling Drug Inc. Hydroxylapatite ceramic
JPS5951485B2 (ja) * 1977-03-11 1984-12-14 東京医科歯科大学長 CaO−P↓2O↓5系アパタイトの製造法
DE2808425A1 (de) * 1978-02-27 1979-08-30 Pluss Stauffer Ag Mineralischer fuellstoff
EP0006414B1 (de) 1978-06-29 1984-10-10 Osteo Ag Mit Kohlenstoffasern verstärkter Knochenzement
GB2025912A (en) * 1978-07-21 1980-01-30 Spencer M Process for preparing a crystalline form of calcium phosphate
JPS5645814A (en) 1979-09-25 1981-04-25 Kureha Chem Ind Co Ltd Hydroxyapatite, its ceramic material and its manufacture
JPS5654841A (en) * 1979-10-08 1981-05-15 Mitsubishi Mining & Cement Co Bone broken portion and filler for void portion and method of treating bone of animal using said filler
USRE33121E (en) 1980-05-08 1989-11-28 Idacon, Inc. Method and composition for treating wood with pentachlorophenol
JPS5925006B2 (ja) * 1980-10-21 1984-06-13 新日本製鐵株式会社 梯形レンガを用いた転炉築造法
US4324772A (en) * 1980-11-19 1982-04-13 Monsanto Company Process for producing hydroxyapatite
JPS5889288A (ja) * 1981-11-19 1983-05-27 オムロン株式会社 電子パズル
DE3211433C2 (de) * 1982-03-27 1984-12-13 Degussa Ag, 6000 Frankfurt Kristallines Alumosilikat PZ 1 und Verfahren zu seiner Herstellung
US4518430A (en) * 1982-04-29 1985-05-21 American Dental Association Health Foundation Dental resptorative cement pastes
USRE33161E (en) 1982-04-29 1990-02-06 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
USRE33221E (en) 1982-04-29 1990-05-22 American Dental Association Health Foundation Dental restorative cement pastes
JPS5956676A (ja) * 1982-09-25 1984-04-02 松下冷機株式会社 冷蔵庫等の冷却装置
US4673355A (en) * 1982-10-25 1987-06-16 Farris Edward T Solid calcium phosphate materials
US4481175A (en) * 1982-12-14 1984-11-06 Mitsui Toatsu Chemicals, Inc. Process for preparing apatite
GB8303188D0 (en) * 1983-02-04 1983-03-09 Thackray C F Ltd Acetabular prostheses
US4612053A (en) * 1983-10-06 1986-09-16 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
US4722948A (en) 1984-03-16 1988-02-02 Dynatech Corporation Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone
DE3433210C1 (de) * 1984-09-10 1986-06-05 Hans Dr.med. Dr.med.dent. 8000 München Scheicher Mittel zur Fuellung von Knochen- und Zahndefekten,zum Knochenaufbau,fuer Knochenkontaktschichten und fuer Knochen- und Zahnwurzelersatz und Verwendung von Carbonatapatit fuer diesen Zweck
US4637931A (en) 1984-10-09 1987-01-20 The United States Of America As Represented By The Secretary Of The Army Polyactic-polyglycolic acid copolymer combined with decalcified freeze-dried bone for use as a bone repair material
US4595713A (en) 1985-01-22 1986-06-17 Hexcel Corporation Medical putty for tissue augmentation
US5246457A (en) 1985-03-28 1993-09-21 Collagen Corporation Xenogeneic collagen/mineral preparations in bone repair
US4668295A (en) 1985-04-25 1987-05-26 University Of Dayton Surgical cements
GB8514055D0 (en) 1985-06-04 1985-07-10 Geistlich Soehne Ag Chemical substance
JPS624637A (ja) * 1985-06-28 1987-01-10 Jidosha Denki Kogyo Co Ltd 車速自動制御装置
US4645503A (en) 1985-08-27 1987-02-24 Orthomatrix Inc. Moldable bone-implant material
JPS62182146A (ja) * 1985-10-11 1987-08-10 三井東圧化学株式会社 硬化性材料
JPH0695784B2 (ja) * 1986-02-20 1994-11-24 松下電工株式会社 遠隔監視制御装置の操作用端末器
JPS63252913A (ja) * 1987-04-10 1988-10-20 Mitsui Toatsu Chem Inc 硬化性材料
JPS6474591A (en) * 1987-09-17 1989-03-20 Ricoh Kk Multiwindow display device
JPH0644423B2 (ja) * 1987-11-17 1994-06-08 矢崎総業株式会社 ワイヤーハーネスの製造方法
US5180426A (en) * 1987-12-28 1993-01-19 Asahi Kogaku Kogyo K.K. Composition for forming calcium phosphate type setting material and process for producing setting material
JPH01203801A (ja) * 1988-02-09 1989-08-16 Ube Ind Ltd 垂直伝熱管を有した流動床ボイラおよび該ボイラを用いた流動床温水ボイラ
JP2678912B2 (ja) * 1988-04-14 1997-11-19 日本フィルコン株式会社 自動綾分装置及び綾分方法
US5962028A (en) * 1988-04-20 1999-10-05 Norian Corporation Carbonated hydroxyapatite compositions and uses
US5053212A (en) * 1988-04-20 1991-10-01 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
US5047031A (en) * 1988-04-20 1991-09-10 Norian Corporation In situ calcium phosphate minerals method
US5129905A (en) * 1988-04-20 1992-07-14 Norian Corporation Methods for in situ prepared calcium phosphate minerals
US5178845A (en) * 1988-04-20 1993-01-12 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
US6005162A (en) 1988-04-20 1999-12-21 Norian Corporation Methods of repairing bone
US4880610A (en) * 1988-04-20 1989-11-14 Norian Corporation In situ calcium phosphate minerals--method and composition
US6002065A (en) 1988-04-20 1999-12-14 Norian Corporation Kits for preparing calcium phosphate minerals
JP2768949B2 (ja) * 1988-06-08 1998-06-25 三菱電機株式会社 半導体装置,及びその製造方法
JPH0773602B2 (ja) * 1988-07-23 1995-08-09 新田ゼラチン株式会社 医科用および歯科用硬化性材料
JPH02117444A (ja) * 1988-10-25 1990-05-01 Honda Motor Co Ltd エンジン制御装置
US4863974A (en) 1988-08-03 1989-09-05 W. L. Gore & Associates, Inc. Bone growth matrix and process for making it
US5573771A (en) 1988-08-19 1996-11-12 Osteomedical Limited Medicinal bone mineral products
US5009898A (en) * 1988-09-29 1991-04-23 Kabushiki Kaisha Sangi Antimicrobial hydroxyapatite powders and methods for preparing them
JPH02117445A (ja) * 1988-10-25 1990-05-01 Isuzu Motors Ltd サスペンション装置付きシート
US5034059A (en) 1989-02-17 1991-07-23 Norian Corporation Composition comprising octacalcium phosphate crystals and polypeptide
JP2754689B2 (ja) * 1989-03-28 1998-05-20 東レ株式会社 トリプトファナーゼ生産能を有する形質転換体およびl―トリプトファンの製造法
JPH0645487B2 (ja) * 1989-05-19 1994-06-15 徳山曹達株式会社 硬化材
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5073373A (en) 1989-09-21 1991-12-17 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
JPH03123609A (ja) * 1989-10-06 1991-05-27 Matsushita Electric Ind Co Ltd 浴槽水の循環装置
CA2027921C (en) 1989-10-19 1997-12-09 Nobuo Nakabayashi Bone cement composition, cured product thereof, implant material and process for the preparation of the same
US5322675A (en) * 1990-11-09 1994-06-21 Director-General Of Agency Of Industrial Science And Technology Method of preparing calcium phosphate
JPH03174349A (ja) * 1989-12-01 1991-07-29 Mitsubishi Materials Corp 水硬性リン酸カルシウムセメント
JPH03283213A (ja) * 1990-03-29 1991-12-13 Tokyo Electric Co Ltd ハンディターミナル
US5188670A (en) 1990-04-05 1993-02-23 Norian Corporation Apparatus for hydroxyapatite coatings of substrates
US5164187A (en) 1990-04-05 1992-11-17 Norian Corporation Hydroxyapatite prosthesis coatings
JP2657847B2 (ja) 1990-05-10 1997-09-30 寅雄 大塚 水酸化アパタイト多孔質生体充▲てん▼材並びにその製造方法
US5266248A (en) 1990-05-10 1993-11-30 Torao Ohtsuka Method of producing hydroxylapatite base porous beads filler for an organism
JP3748567B2 (ja) * 1990-07-27 2006-02-22 ノリアン コーポレイション 水酸化リン灰石への前駆体としてのカルシウム及びホスフェート源の均質混合物
DE4124898A1 (de) * 1990-07-27 1992-01-30 Osaka Cement Mit apatit ueberzogene tetracalciumphosphat-teilchen
JP2621622B2 (ja) * 1990-09-27 1997-06-18 三菱マテリアル株式会社 水硬性リン酸カルシウムセメント
US5231169A (en) 1990-10-17 1993-07-27 Norian Corporation Mineralized collagen
US5149368A (en) * 1991-01-10 1992-09-22 Liu Sung Tsuen Resorbable bioactive calcium phosphate cement
US5262166A (en) * 1991-04-17 1993-11-16 Lty Medical Inc Resorbable bioactive phosphate containing cements
JP3000718B2 (ja) * 1991-05-28 2000-01-17 三菱マテリアル株式会社 薬物徐放性リン酸カルシウムセメント
JP3000719B2 (ja) * 1991-05-28 2000-01-17 三菱マテリアル株式会社 水硬性リン酸カルシウムセメント
US5782971B1 (en) * 1991-06-28 1999-09-21 Norian Corp Calcium phosphate cements comprising amorophous calcium phosphate
JPH059383A (ja) * 1991-06-29 1993-01-19 Dainippon Ink & Chem Inc ポリアリーレンサルフアイド樹脂組成物
JPH0523386A (ja) * 1991-07-23 1993-02-02 Mitsubishi Materials Corp リン酸カルシウムセメント
JP2686684B2 (ja) 1991-08-27 1997-12-08 寅雄 大塚 水酸化アパタイトを充填し生体内溶解性繊維により編機されたチューブ網編成物
US5338356A (en) * 1991-10-29 1994-08-16 Mitsubishi Materials Corporation Calcium phosphate granular cement and method for producing same
ES2040626B1 (es) * 1991-11-22 1994-05-16 Boltong Maria G Procedimiento para la obtencion de cementos de fosfatos de calcio y su empleo como biomteriales.
US5769897A (en) 1991-12-13 1998-06-23 Haerle; Anton Synthetic bone
WO1993012736A1 (en) * 1991-12-30 1993-07-08 Norian Corporation Mineralized collagen
US5314476A (en) 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
US5366507A (en) 1992-03-06 1994-11-22 Sottosanti John S Method for use in bone tissue regeneration
US5320844A (en) * 1992-03-12 1994-06-14 Liu Sung Tsuen Composite materials for hard tissue replacement
JPH05319891A (ja) * 1992-05-19 1993-12-03 Mitsubishi Materials Corp 球状α型第3リン酸カルシウム及び水硬性リン酸カルシウムセメント組成物
FR2693716B1 (fr) * 1992-07-20 1994-10-21 Toulouse Inst Nat Polytech Procédé d'obtention d'hydroxyapatite phosphocalcique, applications au comblement osseux ou dentaire, ou au moulage de pièces, et produits utilisés.
JPH0645494A (ja) * 1992-07-22 1994-02-18 Nec Corp 半導体集積回路用パッケージ
US5439951A (en) 1993-03-24 1995-08-08 Children's Medical Center Corporation Isolation of the calcium-phosphate crystals of bone
US5565502A (en) 1993-03-24 1996-10-15 Children's Medical Center Corporation Isolation of the calcium-phosphate crystals of bone
GB9310321D0 (en) * 1993-05-19 1993-06-30 Queen Mary & Westfield College Method for the preparation of carbonated hydroxyapatite compositions
EP0710267A4 (de) * 1993-07-22 1996-07-10 Norian Corp Lagerstabile teilneutralisierte säurezusammensetzungen und ihre verwendungen
US5531791A (en) 1993-07-23 1996-07-02 Bioscience Consultants Composition for repair of defects in osseous tissues, method of making, and prosthesis
EP0639366A1 (de) * 1993-08-19 1995-02-22 Kingstar Technology Limited (Uk) Hydroxylapatit Zement als Zahn- oder Knochenersatz
US6201039B1 (en) * 1993-09-21 2001-03-13 The Penn State Research Foundation Bone substitute composition comprising hydroxyapatite and a method of production therefor
US5525148A (en) * 1993-09-24 1996-06-11 American Dental Association Health Foundation Self-setting calcium phosphate cements and methods for preparing and using them
FR2715853B1 (fr) 1994-02-08 1996-04-26 Centre Nat Rech Scient Composition pour bio-matériau; procédé de préparation.
CA2143733A1 (en) * 1994-03-02 1995-09-03 Yoshikazu Umezu Alpha-tricalcium phosphate ceramic and production method thereof
US5626861A (en) 1994-04-01 1997-05-06 Massachusetts Institute Of Technology Polymeric-hydroxyapatite bone composite
US5496399A (en) * 1994-08-23 1996-03-05 Norian Corporation Storage stable calcium phosphate cements
US5707962A (en) 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof
US5569442A (en) 1994-11-04 1996-10-29 Norian Corporation Reactive tricalcium phosphate compositions and uses
AU5320496A (en) * 1995-03-20 1996-10-08 Penn State Research Foundation, The Hydroxyapatite forming dry particulate agglomerate and methods therefor
US5676976A (en) 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US5788976A (en) 1996-02-12 1998-08-04 Wbk, Inc. Method for effecting bone repair
CN1135842C (zh) 1996-08-06 2004-01-21 星视电视广播公司 带有交互区的电子节目指南
US6037519A (en) 1997-10-20 2000-03-14 Sdgi Holdings, Inc. Ceramic fusion implants and compositions
US5866155A (en) 1996-11-20 1999-02-02 Allegheny Health, Education And Research Foundation Methods for using microsphere polymers in bone replacement matrices and composition produced thereby
KR20000069469A (ko) 1996-12-13 2000-11-25 브렌트 알. 콘티탄쯔 시멘트의 제법, 저장 및 투여
US5972368A (en) 1997-06-11 1999-10-26 Sdgi Holdings, Inc. Bone graft composites and spacers
US5910315A (en) 1997-07-18 1999-06-08 Stevenson; Sharon Allograft tissue material for filling spinal fusion cages or related surgical spaces
US5968999A (en) 1997-10-28 1999-10-19 Charlotte-Mecklenburg Hospital Authority Bone cement compositions
US6030635A (en) 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US5968253A (en) 1998-07-31 1999-10-19 Norian Corporation Calcium phosphate cements comprising antimicrobial agents

Also Published As

Publication number Publication date
ATE378075T1 (de) 2007-11-15
US6334891B1 (en) 2002-01-01
US5952010A (en) 1999-09-14
EP0835668A1 (de) 1998-04-15
ATE174872T1 (de) 1999-01-15
EP0622990A4 (de) 1995-03-29
ES2128442T3 (es) 1999-05-16
DE69322765T2 (de) 1999-06-17
WO1994008458A1 (en) 1994-04-28
EP0622990A1 (de) 1994-11-09
EP0622990B1 (de) 1998-12-23
DE69334185T2 (de) 2008-10-16
US5962028A (en) 1999-10-05
US5900254A (en) 1999-05-04
EP0835668B1 (de) 2007-11-14
DK0622990T3 (da) 1999-08-23
ES2297845T3 (es) 2008-05-01
DE69322765D1 (de) 1999-02-04

Similar Documents

Publication Publication Date Title
DE69334185D1 (de) Biologisch resorbierbare Kalzium Phosphate Zement- Zusammensetzungen
ATE76588T1 (de) Zinkhaltige keramik.
AU692805B2 (en) Ready-mixed, setting type joint compound
FI896036A0 (fi) Kemiskt stabiliseringsfoerfarande foer tungmetallhaltigt damm och slamm saosom ljusbaogsugnsdamm.
ES8604249A1 (es) Un procedimiento para preparar pseudomonato de calcio cris- talino o un hidrato del mismo
DE3772085D1 (de) Wasser- und feuerbestaendiges baumaterial.
ES2172947T3 (es) Procedimiento de preparacion de composiciones de hidroxiapatito carbonatado.
DE69127447D1 (de) Innige mischung von galcium- und phosphat-quellen als hydroxyapatit-vorläufer
TR199600377A1 (tr) Cimento icin alkali ihtiva etmeyen, sivi halde, baglamayi ve sertlesmeyi hizlandirici maddeler.
AU578065B2 (en) Stabilized enzyme conjugate compositions
DE59703767D1 (de) Verwertung von Al-haltigen Reststoffen
ES2178556A1 (es) Cemento de sulfato de calcio con biodegradacion controlada.
ATE74579T1 (de) Selbstnivellierende moertelmischung.
DK0520372T3 (da) Inositol-phosphat-analoger som calciumantagonistiske stoffer
JPS542329A (en) Herbicidal composition
DE3683158D1 (de) Faerbende zusammensetzung.
LV10580A (lv) Farmaceitiska kompozicija un tas iegusanas panemiens
DK0486810T3 (da) Pudsblanding
JPS55158104A (en) Stable calcium hypochlorite composition
SU1508541A1 (ru) Бис-глицинатодихлорпалладоаты кальция или стронция, проявляющие антимикробную активность
BR8805430A (pt) Composicao de fragrancia,uso de 2,4,6-tribromo-3-metilanisol substancialmente puro e processo para melhorar o odor de uma composicao de fragrancia
RU93058241A (ru) Состав для изготовления строительных блоков, строительный элемент и способ его изготовления
UA11798A1 (uk) Сполука твердіючої суміші
HU215679B (hu) Hullámpapírok felületkezelésére alkalmas kompozíció
TH26563A (th) องค์ประกอบคาร์บอเนทที่ทนทานต่อกรด ซึ่งประกอบด้วยส่วนผสมของกรดอ่อนและการใช้ของมัน

Legal Events

Date Code Title Description
8364 No opposition during term of opposition