AP408A - Vaccine composition containing adjuvants. - Google Patents

Vaccine composition containing adjuvants. Download PDF

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Publication number
AP408A
AP408A APAP/P/1993/000541A AP9300541A AP408A AP 408 A AP408 A AP 408A AP 9300541 A AP9300541 A AP 9300541A AP 408 A AP408 A AP 408A
Authority
AP
ARIPO
Prior art keywords
vaccine
antigen
mpl
composition
virus
Prior art date
Application number
APAP/P/1993/000541A
Other languages
English (en)
Other versions
AP9300541A0 (en
Inventor
Jean Paul Prieels
Nathalie Marie-Josephe Claude Garcon-Johnson
Moncef Slaqui
Pietro Pala
Original Assignee
Smithkline Beecham Biologicals S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9213559A external-priority patent/GB9213559D0/en
Priority claimed from GB929226283A external-priority patent/GB9226283D0/en
Priority claimed from GB939304056A external-priority patent/GB9304056D0/en
Application filed by Smithkline Beecham Biologicals S A filed Critical Smithkline Beecham Biologicals S A
Publication of AP9300541A0 publication Critical patent/AP9300541A0/xx
Application granted granted Critical
Publication of AP408A publication Critical patent/AP408A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
APAP/P/1993/000541A 1992-06-25 1993-06-24 Vaccine composition containing adjuvants. AP408A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9213559A GB9213559D0 (en) 1992-06-25 1992-06-25 Vaccines
GB929226283A GB9226283D0 (en) 1992-12-17 1992-12-17 Vaccines
GB939304056A GB9304056D0 (en) 1993-03-01 1993-03-01 Vaccines

Publications (2)

Publication Number Publication Date
AP9300541A0 AP9300541A0 (en) 1993-07-31
AP408A true AP408A (en) 1995-09-27

Family

ID=27266263

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1993/000541A AP408A (en) 1992-06-25 1993-06-24 Vaccine composition containing adjuvants.

Country Status (31)

Country Link
US (2) US5750110A (ko)
EP (2) EP0761231B1 (ko)
JP (1) JP3755890B2 (ko)
KR (1) KR100278157B1 (ko)
CN (1) CN1122530C (ko)
AP (1) AP408A (ko)
AT (2) ATE156710T1 (ko)
AU (1) AU661404B2 (ko)
CA (1) CA2138997C (ko)
CZ (1) CZ282235B6 (ko)
DE (2) DE69313134T2 (ko)
DK (2) DK0761231T3 (ko)
ES (2) ES2108278T3 (ko)
FI (1) FI109767B (ko)
GR (2) GR3025184T3 (ko)
HK (2) HK1022074A1 (ko)
HU (1) HU219808B (ko)
IL (1) IL106109A (ko)
MA (1) MA22911A1 (ko)
MX (1) MX9303773A (ko)
MY (1) MY109278A (ko)
NO (1) NO317546B1 (ko)
NZ (1) NZ253137A (ko)
PL (1) PL170980B1 (ko)
PT (1) PT761231E (ko)
RU (1) RU2118164C1 (ko)
SG (2) SG49909A1 (ko)
SI (1) SI9300335B (ko)
SK (1) SK279188B6 (ko)
UA (1) UA40597C2 (ko)
WO (1) WO1994000153A1 (ko)

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EP0761231A1 (en) 1997-03-12
RU94046232A (ru) 1996-10-10
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EP0671948B1 (en) 1997-08-13
DE69327599T2 (de) 2000-08-10
SG90042A1 (en) 2002-07-23
JPH07508512A (ja) 1995-09-21
CA2138997A1 (en) 1994-01-06
RU2118164C1 (ru) 1998-08-27
HU219808B (hu) 2001-08-28
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DK0761231T3 (da) 2000-05-08
CA2138997C (en) 2003-06-03
FI946064A (fi) 1995-02-22
HK1010097A1 (en) 1999-06-11
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EP0671948A1 (en) 1995-09-20
FI946064A0 (fi) 1994-12-23
GR3025184T3 (en) 1998-02-27
SK159294A3 (en) 1995-08-09
KR950702125A (ko) 1995-06-19
NO945003D0 (no) 1994-12-23
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SI9300335A (sl) 1993-12-31
ATE156710T1 (de) 1997-08-15
SK279188B6 (sk) 1998-07-08
NZ253137A (en) 1996-08-27
PT761231E (pt) 2000-06-30
ATE188613T1 (de) 2000-01-15
US5750110A (en) 1998-05-12
NO317546B1 (no) 2004-11-15
EP0761231B1 (en) 2000-01-12
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NO945003L (no) 1994-12-23
US7147862B1 (en) 2006-12-12
AP9300541A0 (en) 1993-07-31
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CN1086142A (zh) 1994-05-04
PL170980B1 (pl) 1997-02-28
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ES2108278T3 (es) 1997-12-16
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DK0671948T3 (da) 1997-09-01
MA22911A1 (fr) 1993-12-31
ES2143716T3 (es) 2000-05-16
AU4326393A (en) 1994-01-24
IL106109A (en) 1997-02-18
JP3755890B2 (ja) 2006-03-15
AU661404B2 (en) 1995-07-20
IL106109A0 (en) 1993-10-20
UA40597C2 (uk) 2001-08-15
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