ZA200902485B - Native (telopeptide) placental collagen compositions - Google Patents

Native (telopeptide) placental collagen compositions

Info

Publication number
ZA200902485B
ZA200902485B ZA200902485A ZA200902485A ZA200902485B ZA 200902485 B ZA200902485 B ZA 200902485B ZA 200902485 A ZA200902485 A ZA 200902485A ZA 200902485 A ZA200902485 A ZA 200902485A ZA 200902485 B ZA200902485 B ZA 200902485B
Authority
ZA
South Africa
Prior art keywords
telopeptide
native
collagen compositions
placental collagen
placental
Prior art date
Application number
ZA200902485A
Other languages
English (en)
Inventor
Mohit Bhatia
Chris Lugo
Qian Ye
James W Edinger
Original Assignee
Anthrogenesis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anthrogenesis Corp filed Critical Anthrogenesis Corp
Publication of ZA200902485B publication Critical patent/ZA200902485B/xx

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/145Extraction; Separation; Purification by extraction or solubilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B6/12004Combinations of two or more optical elements
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    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
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    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B6/122Basic optical elements, e.g. light-guiding paths
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    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
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    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B6/122Basic optical elements, e.g. light-guiding paths
    • G02B6/1228Tapered waveguides, e.g. integrated spot-size transformers
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B6/122Basic optical elements, e.g. light-guiding paths
    • G02B6/124Geodesic lenses or integrated gratings
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/005Optical components external to the laser cavity, specially adapted therefor, e.g. for homogenisation or merging of the beams or for manipulating laser pulses, e.g. pulse shaping
    • H01S5/0064Anti-reflection components, e.g. optical isolators
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/02Structural details or components not essential to laser action
    • H01S5/026Monolithically integrated components, e.g. waveguides, monitoring photo-detectors, drivers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/10Construction or shape of the optical resonator, e.g. extended or external cavity, coupled cavities, bent-guide, varying width, thickness or composition of the active region
    • H01S5/1028Coupling to elements in the cavity, e.g. coupling to waveguides adjacent the active region, e.g. forward coupled [DFC] structures
    • H01S5/1032Coupling to elements comprising an optical axis that is not aligned with the optical axis of the active region
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/10Construction or shape of the optical resonator, e.g. extended or external cavity, coupled cavities, bent-guide, varying width, thickness or composition of the active region
    • H01S5/18Surface-emitting [SE] lasers, e.g. having both horizontal and vertical cavities
    • H01S5/185Surface-emitting [SE] lasers, e.g. having both horizontal and vertical cavities having only horizontal cavities, e.g. horizontal cavity surface-emitting lasers [HCSEL]
    • H01S5/187Surface-emitting [SE] lasers, e.g. having both horizontal and vertical cavities having only horizontal cavities, e.g. horizontal cavity surface-emitting lasers [HCSEL] using Bragg reflection
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/20Structure or shape of the semiconductor body to guide the optical wave ; Confining structures perpendicular to the optical axis, e.g. index or gain guiding, stripe geometry, broad area lasers, gain tailoring, transverse or lateral reflectors, special cladding structures, MQW barrier reflection layers
    • H01S5/22Structure or shape of the semiconductor body to guide the optical wave ; Confining structures perpendicular to the optical axis, e.g. index or gain guiding, stripe geometry, broad area lasers, gain tailoring, transverse or lateral reflectors, special cladding structures, MQW barrier reflection layers having a ridge or stripe structure
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/30Structure or shape of the active region; Materials used for the active region
    • H01S5/3013AIIIBV compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92Oral administration
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/10Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type
    • G02B6/12Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
    • G02B2006/12133Functions
    • G02B2006/12147Coupler
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/24Coupling light guides
    • G02B6/26Optical coupling means
    • G02B6/27Optical coupling means with polarisation selective and adjusting means
    • G02B6/2746Optical coupling means with polarisation selective and adjusting means comprising non-reciprocal devices, e.g. isolators, FRM, circulators, quasi-isolators
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/02Structural details or components not essential to laser action
    • H01S5/022Mountings; Housings
    • H01S5/023Mount members, e.g. sub-mount members
    • H01S5/02325Mechanically integrated components on mount members or optical micro-benches
    • H01S5/02326Arrangements for relative positioning of laser diodes and optical components, e.g. grooves in the mount to fix optical fibres or lenses
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/10Construction or shape of the optical resonator, e.g. extended or external cavity, coupled cavities, bent-guide, varying width, thickness or composition of the active region
    • H01S5/1028Coupling to elements in the cavity, e.g. coupling to waveguides adjacent the active region, e.g. forward coupled [DFC] structures
    • H01S5/1032Coupling to elements comprising an optical axis that is not aligned with the optical axis of the active region
    • H01S5/1035Forward coupled structures [DFC]
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/10Construction or shape of the optical resonator, e.g. extended or external cavity, coupled cavities, bent-guide, varying width, thickness or composition of the active region
    • H01S5/12Construction or shape of the optical resonator, e.g. extended or external cavity, coupled cavities, bent-guide, varying width, thickness or composition of the active region the resonator having a periodic structure, e.g. in distributed feedback [DFB] lasers
    • H01S5/125Distributed Bragg reflector [DBR] lasers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01SDEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S5/00Semiconductor lasers
    • H01S5/20Structure or shape of the semiconductor body to guide the optical wave ; Confining structures perpendicular to the optical axis, e.g. index or gain guiding, stripe geometry, broad area lasers, gain tailoring, transverse or lateral reflectors, special cladding structures, MQW barrier reflection layers
    • H01S5/2004Confining in the direction perpendicular to the layer structure
    • H01S5/2018Optical confinement, e.g. absorbing-, reflecting- or waveguide-layers
    • H01S5/2027Reflecting region or layer, parallel to the active layer, e.g. to modify propagation of the mode in the laser or to influence transverse modes

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  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Dermatology (AREA)
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ZA200902485A 2006-10-06 2007-10-09 Native (telopeptide) placental collagen compositions ZA200902485B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85013106P 2006-10-06 2006-10-06

Publications (1)

Publication Number Publication Date
ZA200902485B true ZA200902485B (en) 2010-07-28

Family

ID=39283954

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200902485A ZA200902485B (en) 2006-10-06 2007-10-09 Native (telopeptide) placental collagen compositions

Country Status (14)

Country Link
US (10) US20080181935A1 (zh)
EP (3) EP2076279B1 (zh)
JP (6) JP5769925B2 (zh)
KR (8) KR101595108B1 (zh)
CN (3) CN104623642A (zh)
AU (1) AU2007318210B2 (zh)
CA (2) CA3178363A1 (zh)
ES (1) ES2516698T3 (zh)
HK (1) HK1127561A1 (zh)
IL (4) IL198015A (zh)
MX (2) MX354253B (zh)
NZ (3) NZ612094A (zh)
WO (1) WO2008057162A2 (zh)
ZA (1) ZA200902485B (zh)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322601A1 (en) 2000-12-06 2011-05-18 Anthrogenesis Corporation Method of collecting placental stem cells
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
IL157392A0 (en) 2001-02-14 2004-02-19 Robert J Hariri Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
BR0205047C1 (pt) * 2002-11-21 2003-11-04 Ronaldo Da Rocha Loures Bueno Endoprótese revestida com membrana de celulose biossintética
AU2003298775B2 (en) * 2002-11-26 2008-07-17 Anthrogenesis Corporation Cytotherapeutics, cytotherapeutic units and methods for treatments using them
CA2560725A1 (en) * 2004-03-26 2005-10-20 Celgene Corporation Systems and methods for providing a stem cell bank
CA2949643C (en) 2005-09-27 2018-05-15 Tissuetech, Inc. Amniotic membrane preparations and purified compositions and methods of use
US8187639B2 (en) 2005-09-27 2012-05-29 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment
NZ612132A (en) 2005-10-13 2015-01-30 Anthrogenesis Corp Immunomodulation using placental stem cells
WO2007047465A1 (en) * 2005-10-13 2007-04-26 Anthrogenesis Corporation Production of oligodendrocytes from placenta-derived stem cells
ES2549111T3 (es) 2005-12-29 2015-10-23 Anthrogenesis Corporation Poblaciones de células madre placentarias
WO2007079184A2 (en) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
AU2006332680A1 (en) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Improved composition for collecting and preserving placental stem cells and methods of using the composition
US20070269476A1 (en) 2006-05-16 2007-11-22 Voytik-Harbin Sherry L Engineered extracellular matrices control stem cell behavior
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
GB2455041B (en) 2006-09-21 2012-03-07 Purdue Research Foundation Collagen preparation and method of isolation
KR101595108B1 (ko) * 2006-10-06 2016-02-18 안트로제네시스 코포레이션 천연(텔로펩티드) 태반 콜라겐 조성물
EP2084268B1 (en) * 2006-10-23 2018-09-26 Celularity, Inc. Methods and compositions for treatment of bone defects with placental cell populations
NZ597779A (en) 2007-02-12 2013-07-26 Anthrogenesis Corp Treatment of inflammatory diseases using placental stem cells
JP2010518812A (ja) 2007-02-12 2010-06-03 アンスロジェネシス コーポレーション 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにcd34+、cd45−胎盤幹細胞の濃縮細胞集団
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
WO2009033160A1 (en) 2007-09-07 2009-03-12 Surgical Biologics Placental tissue grafts and improved methods of preparing and using the same
DK2203176T3 (en) 2007-09-28 2015-02-09 Anthrogenesis Corp Tumor suppression with human placental perfusate and human natural killer cells of an intermediate product from placenta
US9480549B2 (en) 2008-04-25 2016-11-01 Allosource Multi-layer tissue patches
US9358320B2 (en) 2008-04-25 2016-06-07 Allosource Multi-layer tissue patches
EP3172963B1 (en) 2008-08-20 2019-02-06 Celularity, Inc. Improved cell composition and methods of making the same
CN105796602A (zh) 2008-08-20 2016-07-27 人类起源公司 利用分离的胎盘细胞治疗中风
MX339068B (es) 2008-08-22 2016-05-10 Anthrogenesis Corp Metodos y composiciones para el tratamiento de defectos oseos con poblaciones de celulas placentarias.
WO2010040262A1 (zh) * 2008-10-10 2010-04-15 深圳市嘉天源生物科技有限公司 分离动物胚胎间质性干细胞并提取其分泌物的方法
MX2011005229A (es) 2008-11-19 2011-06-16 Anthrogenesis Corp Celulas adherentes derivadas del amnios.
MX2012000110A (es) 2009-07-02 2012-04-02 Anthrogenesis Corp Metodo para producir eritrocitos sin celulas alimetadoras.
WO2011014741A1 (en) * 2009-07-31 2011-02-03 Artemis Health, Inc. Methods and compositions for cell stabilization
MY160388A (en) * 2009-10-07 2017-03-15 Kerecis Ehf A scaffold material for wound care and/or other tissue healing applications
US20110165676A1 (en) * 2009-11-06 2011-07-07 The Children's Mercy Hospital Method for decellularization
US9121007B2 (en) 2010-01-26 2015-09-01 Anthrogenesis Corporatin Treatment of bone-related cancers using placental stem cells
US20150010506A1 (en) * 2010-02-18 2015-01-08 Osiris Therapeutics, Inc. Therapeutic placental compositions, methods of making and methods of use
US20110212065A1 (en) * 2010-02-18 2011-09-01 Timothy Jansen Methods of manufacture of therapeutic products comprising vitalized placental dispersions
TW201902496A (zh) 2010-04-07 2019-01-16 美商安瑟吉納西斯公司 利用胎盤幹細胞之血管新生
JP2013523823A (ja) 2010-04-08 2013-06-17 アントフロゲネシス コーポレーション 胎盤幹細胞を用いるサルコイドーシスの治療
US9999702B2 (en) 2010-04-09 2018-06-19 Kci Licensing Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
CN107760648A (zh) 2010-07-13 2018-03-06 人类起源公司 产生自然杀伤细胞的方法、由此获得的细胞群体及其用途
US20120027732A1 (en) * 2010-07-27 2012-02-02 Voytik-Harbin Sherry L Thermoreversible collagen
EP2658557A1 (en) 2010-12-31 2013-11-06 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
KR20240042159A (ko) 2011-02-14 2024-04-01 미메딕스 그룹 인크. 마이크로화된 태반 조직 조성물 및 이의 제조 및 사용 방법
US8597264B2 (en) 2011-03-24 2013-12-03 Kci Licensing, Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
US9623051B2 (en) * 2011-04-15 2017-04-18 The Regents Of The University Of California Decellularized extracellular matrix
US9526770B2 (en) * 2011-04-28 2016-12-27 Tissuetech, Inc. Methods of modulating bone remodeling
EP2714059B1 (en) 2011-06-01 2018-10-03 Celularity, Inc. Treatment of pain using placental stem cells
JP6416622B2 (ja) * 2011-06-21 2018-10-31 ジョージア・テック・リサーチ・コーポレイション 幹細胞および幹細胞に由来する細胞を単離するための、接着シグネチャーベースの方法
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
US9162011B2 (en) 2011-12-19 2015-10-20 Allosource Flowable matrix compositions and methods
CN102552099B (zh) * 2011-12-30 2014-06-18 王英丽 一种用于皮肤美容修复的复合生物制剂及制备方法
US9023416B2 (en) 2012-01-27 2015-05-05 Cartilast II LLC Preservation of the biological activity of undenatured type II collagen
US10576037B2 (en) * 2012-03-14 2020-03-03 MAM Holdings of West Florida, L.L.C. Compositions comprising placental collagen for use in wound healing
US9644177B2 (en) * 2012-07-12 2017-05-09 Board Of Regents, The University Of Texas System Extracellular matrix films and methods of making and using same
US9943551B2 (en) 2012-08-15 2018-04-17 Mimedx Group, Inc. Tissue grafts composed of micronized placental tissue and methods of making and using the same
WO2014039429A1 (en) * 2012-09-04 2014-03-13 Anthrogenesis Corporation Methods of tissue generation
US20150224226A1 (en) * 2012-09-04 2015-08-13 Anthrogenesis Corporation Methods of tissue generation
ES2756332T3 (es) 2012-09-10 2020-04-27 Univ Wake Forest Health Sciences Membrana amniótica y su uso en cicatrización de heridas y construcciones de ingeniería tisular
US9155799B2 (en) 2012-11-19 2015-10-13 Mimedx Group, Inc. Cross-linked collagen with at least one bound antimicrobial agent for in vivo release of the agent
US8946163B2 (en) 2012-11-19 2015-02-03 Mimedx Group, Inc. Cross-linked collagen comprising metallic anticancer agents
WO2014089440A1 (en) * 2012-12-07 2014-06-12 Anthrogenesis Corporation Treating oral lesions using placental extracellular matrix
EP3622960A1 (en) 2013-02-05 2020-03-18 Celularity, Inc. Natural killer cells from placenta
ES2764146T3 (es) 2013-02-08 2020-06-02 Acell Inc Métodos para fabricar geles bioactivos a partir de material de la matriz extracelular
US9770472B1 (en) 2013-03-08 2017-09-26 Brahm Holdings, Llc Organ jacket and methods of use
CA2899246C (en) 2013-03-13 2022-12-06 Allosource Fascia fibrous compositions and methods for their use and manufacture
EP2976095B1 (en) * 2013-03-15 2020-12-23 3M Innovative Properties Company Wound healing compositions
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
NO2975611T3 (zh) * 2013-03-15 2018-06-09
CA2899713C (en) 2013-03-15 2022-07-19 Allosource Cell repopulated collagen matrix for soft tissue repair and regeneration
US10555897B1 (en) 2013-03-16 2020-02-11 Brahm Holdings Llc Cosmetic composition and methods of treatment
US10485521B2 (en) 2013-05-10 2019-11-26 MAM Holdings of West Florida, L.L.C. Method for obtaining sterile human amniotic fluid and uses thereof
US20140336600A1 (en) 2013-05-10 2014-11-13 Carl Randall Harrell Method for Obtaining Sterile Human Amniotic Fluid and Uses Thereof
US9446142B2 (en) * 2013-05-28 2016-09-20 Mimedx Group, Inc. Polymer chelator conjugates
US20160304832A1 (en) * 2013-06-24 2016-10-20 Anthrogenesis Corporation Extracellular matrix composition beads for cell culture
CA2919374C (en) 2013-07-30 2019-12-03 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
WO2015017772A1 (en) * 2013-08-01 2015-02-05 Parcell Laboratories, Llc Stem cell-based preparations and methods for dermal and connective tissue reconstruction and rejuvenation
JP6756612B2 (ja) 2013-08-30 2020-09-16 ミメディクス グループ インコーポレイテッド キレーターを含む微粒子化した胎盤性組成物
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
CA2925332C (en) 2013-11-04 2022-07-12 Lifecell Corporation Methods of removing alpha-galactose
KR101832203B1 (ko) 2013-12-06 2018-02-27 알로소스 조직의 시트를 건조하는 방법
CA2933607A1 (en) * 2013-12-19 2015-06-25 Basf Se Mixtures comprising a superabsorbent polymer (sap) and a biopesticide
US20150216947A1 (en) * 2014-02-03 2015-08-06 George D. Petito Method and composition for tissue/cell repair
US20160354408A1 (en) * 2014-02-11 2016-12-08 Anthrogenesis Corporation Micro-organoids, and methods of making and using the same
WO2015122867A1 (en) * 2014-02-15 2015-08-20 Cartilast Corporation Preservation of the biological activity of undenatured type ii collagen
US20170015973A1 (en) * 2014-03-10 2017-01-19 Medtrain Technologies, Llc Collagen hydrogel kit and methods of making a collagen hydrogel
CN104195205B (zh) * 2014-04-24 2019-08-16 吉林金梓源生物科技股份有限公司 从动物胎盘制备高活性胶原蛋白肽的方法与所制备的高活性胶原蛋白肽及其用途
CN105267243B (zh) * 2014-07-23 2020-03-20 深圳培元生物科技有限公司 一种消除皮肤妊娠纹的干细胞提取物
BR112017003905A2 (pt) * 2014-08-25 2018-03-06 Hli Cellular Therapeutics Llc composições da matriz extracelular
EP3197467A4 (en) * 2014-09-26 2018-05-23 Anthrogenesis Corporation Treatment of diabetic foot ulcer using placental stem cells
US20160095307A1 (en) * 2014-10-07 2016-04-07 NuTech Medical, Inc. Method and composition for hypothermic storage of placental tissue
US20160287750A1 (en) * 2014-12-31 2016-10-06 Applied Biologics, Llc Standardized amniotic membrane tissue graft
WO2016149194A1 (en) 2015-03-13 2016-09-22 MAM Holdings of West Florida, L.L.C. Collagen compositions and uses for biomaterial implants
WO2016172365A1 (en) 2015-04-21 2016-10-27 Purdue Research Foundation Office Of Technology Commercialization Cell-collagen-silica composites and methods of making and using the same
CN104818264A (zh) * 2015-05-29 2015-08-05 广州赛莱拉干细胞科技股份有限公司 一种消化酶组合物及其制剂、应用
US11077147B2 (en) * 2015-07-20 2021-08-03 Vivex Biologics Group, Inc. Acellular biologic composition and method of manufacture
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
US11273183B2 (en) 2015-10-09 2022-03-15 MAM Holdings of West Florida, L.L.C. Amniotic fluid formulation for treatment of joint pain or disorders
WO2017062937A1 (en) 2015-10-09 2017-04-13 Mam Holdings Of West Florida, Llc Amniotic fluid formulation for treatment of joint pain or disorder
US20170100440A1 (en) 2015-10-09 2017-04-13 MAM Holdings of West Florida, L.L.C. Amniotic fluid topical formulation
TW201733600A (zh) 2016-01-29 2017-10-01 帝聖工業公司 胎兒扶持組織物及使用方法
JP6712160B2 (ja) * 2016-03-29 2020-06-17 株式会社Adeka エンドトキシン測定のための前処理方法及びその測定方法
WO2017180862A1 (en) * 2016-04-13 2017-10-19 Northeast Ohio Medical University Gpnmb compositions for treatment of skin wounds
US20170354692A1 (en) 2016-06-13 2017-12-14 MAM Holdings of West Florida, L.L.C. Amniotic fluid formulation for treatment of lung disorders
JPWO2018047785A1 (ja) * 2016-09-07 2019-06-24 ナガセケムテックス株式会社 コラーゲン様ポリペプチド
CN106421871A (zh) * 2016-09-29 2017-02-22 广州赛莱拉干细胞科技股份有限公司 一种喷雾型医用胶原贴敷料及其制备方法
US10772986B2 (en) 2017-01-26 2020-09-15 Allosource Fascia fibrous compositions and methods for their use and manufacture
US20200023014A1 (en) * 2017-02-03 2020-01-23 Biocellix Spa Collagen membrane or matrix with antimicrobial properties
EP3615568A4 (en) 2017-04-25 2021-01-20 Purdue Research Foundation TISSUE RESTORATION THREE-DIMENSIONAL (3D) ARTIFICIAL MUSCLE
CN107596428A (zh) * 2017-09-25 2018-01-19 北京华信佳音医疗科技发展有限责任公司 一种胶原止血海绵及其制备方法
JPWO2019189786A1 (ja) * 2018-03-29 2021-03-25 凸版印刷株式会社 細胞培養用シート並びに三次元組織体及びその製造方法
CN108642115A (zh) * 2018-06-28 2018-10-12 中国科学院青岛生物能源与过程研究所 一种高质量可放大型鱼胶原蛋白提取纯化方法
US11369718B1 (en) 2018-08-24 2022-06-28 Ariasa LLC Method and use of cryopreserved mesenchymal stem cells via liquid suspension from the amniotic sac for rejuvenation of the midface
CN109671346B (zh) * 2019-01-17 2021-11-19 南方科技大学 肝脏模型及其制备方法和应用
CN109675085B (zh) * 2019-02-26 2021-09-28 百澳瑞派(天津)生物科技有限公司 一种用于烧伤创面修复的复合胶原敷料及其制备方法
CN109985271B (zh) * 2019-02-26 2021-10-22 百澳瑞派(天津)生物科技有限公司 一种用于难愈合创面修复的复合胶原敷料及其制备方法
TW202042785A (zh) * 2019-04-01 2020-12-01 美商格爾托公司 重組膠原蛋白之局部調配物
WO2020203579A1 (ja) * 2019-04-01 2020-10-08 凸版印刷株式会社 三次元組織体及びその製造方法並びに細胞含有組成物の製造方法
CN113134116B (zh) * 2020-01-20 2022-09-06 山东威高宏瑞医学科技有限公司 内镜微创手术用的填充组合物及填充制剂
EP4149491A4 (en) * 2020-05-15 2023-11-15 Mayo Foundation for Medical Education and Research BIOACTIVE TISSUE MADE OF NANOCOMPOSITE HYDROGELS FOR PERMANENT ARTERIAL EMBOLIZATION AND IMPROVED VESSEL HEALING
KR102618453B1 (ko) * 2021-06-04 2024-01-02 주식회사 휴코드바이오 제대혈 줄기세포 배양액을 포함하는 피부 튼살 예방 또는 개선용 조성물
CN113444761B (zh) * 2021-08-17 2022-09-09 中国海洋大学 一种低免疫原性鱼皮胶原蛋白及其制备方法

Family Cites Families (148)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3157524A (en) 1960-10-25 1964-11-17 Ethicon Inc Preparation of collagen sponge
US3800792A (en) 1972-04-17 1974-04-02 Johnson & Johnson Laminated collagen film dressing
DE2321306C2 (de) * 1973-04-27 1988-08-18 Böttger GmbH Pharmazeutische und Kosmetische Präparate, 1000 Berlin Hautpflegemittel
DE2462221A1 (de) * 1974-02-02 1976-05-06 Trommsdorff Fa H Kosmetisches mittel, enthaltend loesliches, natives human-kollagen
US4060081A (en) 1975-07-15 1977-11-29 Massachusetts Institute Of Technology Multilayer membrane useful as synthetic skin
US4185011A (en) 1978-10-16 1980-01-22 Firma Carl Freudenberg Process for the production of collagen fibers
DE2943520C2 (de) * 1979-10-27 1982-05-19 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von Kollagenschwamm für medizinische oder kosmetische Zwecke
US4361552A (en) * 1980-09-26 1982-11-30 Board Of Regents, The University Of Texas System Wound dressing
DE3042860A1 (de) 1980-11-13 1982-06-09 Heyl & Co Chemisch-Pharmazeutische Fabrik, 1000 Berlin Kollagenpraeparate, verfahren zu ihrer herstellung und ihre verwendung in der human- und veterinaermedizin
US4420339A (en) * 1981-03-27 1983-12-13 Kureha Kagaku Kogyo Kabushiki Kaisha Collagen fibers for use in medical treatments
FR2516927B1 (fr) 1981-11-26 1986-05-23 Merieux Fond Procede de preparation industrielle de materiaux collageniques a partir de tissus placentaires humains, materiaux collageniques humains obtenus, leur application comme biomateriaux
US4582640A (en) 1982-03-08 1986-04-15 Collagen Corporation Injectable cross-linked collagen implant material
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
DE3248188A1 (de) * 1982-12-27 1984-06-28 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung eines kollagen-vlieses
US4599226A (en) * 1983-03-31 1986-07-08 Genetic Laboratories, Inc. Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation
SU1286211A1 (ru) 1983-04-18 1987-01-30 Кишиневский государственный медицинский институт Способ лечени рубцов
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
US4837285A (en) 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4642117A (en) 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US5230693A (en) * 1985-06-06 1993-07-27 Thomas Jefferson University Implantable prosthetic device for implantation into a human patient having a surface treated with microvascular endothelial cells
US5436135A (en) 1985-09-02 1995-07-25 Pasteur Merieux Serums Et Vaccins New preparation of placenta collagen, their extraction method and their applications
US4883864A (en) * 1985-09-06 1989-11-28 Minnesota Mining And Manufacturing Company Modified collagen compound and method of preparation
CA1284250C (en) 1985-09-06 1991-05-14 Dale P. Devore Viscoelastic collagen solution for ophthalmic use and method of preparation
US4772284A (en) * 1986-03-27 1988-09-20 Collagenix Corporation Breast prosthesis with improved biocompatibility and method of making the same
US4852640A (en) 1986-03-28 1989-08-01 Exothermics-Eclipse Inc. Recuperative heat exchanger
JPS62268875A (ja) 1986-05-14 1987-11-21 東レ株式会社 繊維シ−ト状物
FR2613620B1 (fr) 1987-04-13 1991-04-19 Krom Robert Implant destine a la medecine humaine
ATE86115T1 (de) 1987-04-28 1993-03-15 Univ California Vorrichtung und verfahren zur herstellung eines komposithautersatzes.
FR2617488B1 (fr) * 1987-07-01 1990-03-09 Tab Procede de fabrication de structures organisees de collagene, notamment d'origine humaine, et structures organisees de collagene correspondantes
US5036056A (en) * 1987-07-08 1991-07-30 Martin Kludas Methods for treating damaged corneal, uterine, or cartilage tissue
GB8803697D0 (en) * 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
US4969912A (en) * 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5660692A (en) 1988-02-24 1997-08-26 Cedars-Sinai Medical Center Method of crosslinking amino acid-containing polymers using photoactivatable chemical crosslinkers
ATE109491T1 (de) * 1988-03-11 1994-08-15 Chemokol G B R Ing Buero Fuer Verfahren zur herstellung von kollagenmembranen für hämostase, wundbehandlung und implantate.
US5008116A (en) 1988-11-14 1991-04-16 Frederick Cahn Immunostimulatory microsphere
US5162430A (en) * 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5141747A (en) * 1989-05-23 1992-08-25 Minnesota Mining And Manufacturing Company Denatured collagen membrane
CA2015495A1 (en) 1989-05-23 1990-11-23 David C. Muchow Modifying a membrane for use as a graft
US5116620A (en) 1989-11-21 1992-05-26 Bruce A. Barber Antimicrobial wound dressing
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
AU652022B2 (en) * 1991-02-12 1994-08-11 C.R. Bard Inc. Injectable medical device
NL9101149A (nl) 1991-07-01 1993-02-01 Wilhelmus Hubertus Maria Van E Preparaat voor medische en/of cosmetische toepassing met als werkzaam bestanddeel placentacomplex, werkwijze voor de bereiding ervan en werkwijze voor de medische toepassing.
CA2071137A1 (en) * 1991-07-10 1993-01-11 Clarence C. Lee Composition and method for revitalizing scar tissue
JPH0556987A (ja) 1991-09-05 1993-03-09 A M D:Kk 医療用具の原料用膜材料の製造方法
FR2692582B1 (fr) 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
US5428022A (en) 1992-07-29 1995-06-27 Collagen Corporation Composition of low type III content human placental collagen
US5830548A (en) * 1992-08-11 1998-11-03 E. Khashoggi Industries, Llc Articles of manufacture and methods for manufacturing laminate structures including inorganically filled sheets
US5827641A (en) 1992-11-13 1998-10-27 Parenteau; Nancy L. In vitro cornea equivalent model
FR2699184B1 (fr) 1992-12-16 1995-03-10 Flamel Tech Sa Nouveaux dérivés de collagène, leur procédé d'obtention et leur application à la préparation de biomatériaux.
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
IT1263316B (it) * 1993-02-12 1996-08-05 Fidia Advanced Biopolymers Srl Tessuto non tessuto multistrato in cui uno degli strati e' costituito essenzialmente da esteri dell'acido ialuronico
US5698579A (en) * 1993-07-02 1997-12-16 Celgene Corporation Cyclic amides
JP3542170B2 (ja) 1993-08-06 2004-07-14 株式会社アムニオテック 医用材料及びその製造方法
US5607590A (en) * 1993-08-06 1997-03-04 Shimizu; Yasuhiko Material for medical use and process for preparing same
US5523291A (en) * 1993-09-07 1996-06-04 Datascope Investment Corp. Injectable compositions for soft tissue augmentation
GB9400163D0 (en) * 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
ATE250901T1 (de) 1994-02-18 2003-10-15 Organogenesis Inc Bioumbaubare collagentransplantat prothese
US5656478A (en) * 1994-02-25 1997-08-12 The Regents Of The University Of California Smooth muscle tissue formation in vivo using cultured smooth muscle cells combined with an extracellular matrix
EP0713707A1 (en) 1994-11-23 1996-05-29 Collagen Corporation In situ crosslinkable, injectable collagen composition for tissue augmention
US6337389B1 (en) * 1995-03-17 2002-01-08 Bioscience Consultants, L.L.C. Method and process for the production of collagen preparations from invertebrate marine animals and compositions thereof
US5723010A (en) * 1995-03-31 1998-03-03 Toyo Boseki Kabushiki Kaisha Medical device and method for producing the same
JPH09122225A (ja) * 1995-10-31 1997-05-13 Bio Eng Lab:Kk 医用材料の原料膜材およびその製造方法
JPH09122227A (ja) * 1995-10-31 1997-05-13 Bio Eng Lab:Kk 医用材料およびその製造方法
JP3476631B2 (ja) 1995-12-21 2003-12-10 株式会社アムニオテック ヒト由来の天然コラーゲン膜からなる医用材料
JP2000506050A (ja) 1996-03-04 2000-05-23 バクスター・インターナショナル・インコーポレイテッド 生物学的組織を架橋するための非ポリマー性エポキシ化合物およびそれにより調製される生体補綴移植片
CN1061812C (zh) * 1996-04-01 2001-02-14 胡杰 制备皮肤移植体的方法
US5939323A (en) * 1996-05-28 1999-08-17 Brown University Hyaluronan based biodegradable scaffolds for tissue repair
AU7003096A (en) 1996-06-21 1998-01-07 Jury Evgenievich Belyaev Semi-finished product for producing drug bases, bases obtained using the same and variants, and drugs obtained using these bases and variants
HU228769B1 (en) 1996-07-24 2013-05-28 Celgene Corp Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha
DE122007000079I2 (de) 1996-07-24 2010-08-12 Celgene Corp Substituierte 2-(2,6-dioxopiperidin-3-yl)-phthalimide und -1-oxoisoindoline und verfahren zur reduzierung des tnf-alpha-spiegels
US5635517B1 (en) * 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
US6281230B1 (en) * 1996-07-24 2001-08-28 Celgene Corporation Isoindolines, method of use, and pharmaceutical compositions
US5798368A (en) * 1996-08-22 1998-08-25 Celgene Corporation Tetrasubstituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines and method of reducing TNFα levels
CN1263731C (zh) * 1996-08-12 2006-07-12 赛尔金有限公司 新的治疗免疫剂及其在降低细胞因子水平中的应用
US5814328A (en) * 1997-01-13 1998-09-29 Gunasekaran; Subramanian Preparation of collagen using papain and a reducing agent
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
US5993844A (en) * 1997-05-08 1999-11-30 Organogenesis, Inc. Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix
US6379323B1 (en) * 1997-05-09 2002-04-30 Acoustic Technologies, Inc. Bio erodable myringotomy tube
PT1028737E (pt) * 1997-07-03 2007-07-11 Osiris Therapeutics Inc Células estaminais mesenquimatosas humanas de sangue periférico
US6143315A (en) * 1997-07-24 2000-11-07 Wang; Ming X. Biochemical contact lens for treating injured corneal tissue
US5932205A (en) * 1997-07-24 1999-08-03 Wang; Ming X. Biochemical contact lens for treating photoablated corneal tissue
US6117979A (en) 1997-08-18 2000-09-12 Medtronic, Inc. Process for making a bioprosthetic device and implants produced therefrom
US5955476A (en) * 1997-11-18 1999-09-21 Celgene Corporation Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels
US5874448A (en) * 1997-11-18 1999-02-23 Celgene Corporation Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels
US6371992B1 (en) * 1997-12-19 2002-04-16 The Regents Of The University Of California Acellular matrix grafts: preparation and use
US6113932A (en) * 1998-03-02 2000-09-05 Children's Hospital Medical Center Nontoxic vernix compositions and method of producing
US20010006973A1 (en) * 1998-03-16 2001-07-05 Hon-Wah Man 1-oxo- and 1,3-dioxoisoindolines and method of reducing inflammatory cytokine levels
US6432710B1 (en) 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
AU4221399A (en) * 1998-05-29 1999-12-13 Osiris Therapeutics, Inc. Human cd45+ and/or fibroblast + mesenchymal stem cells
ES2323661T3 (es) 1998-06-05 2009-07-22 Organogenesis Inc. Metodo de preparacion de una protesis vascular.
US6110196A (en) 1998-06-17 2000-08-29 Edwards; Stuart D. Apparatus and method for tympanic membrane tightening
US6734018B2 (en) * 1999-06-07 2004-05-11 Lifenet Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced
US6093417A (en) * 1999-01-11 2000-07-25 Advanced Medical Instruments Composition to treat ear disorders
JP2000237300A (ja) 1999-02-23 2000-09-05 Djk Research Center:Kk 細孔径の中空糸およびその中空糸束とその製造方法
US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US20020090725A1 (en) * 2000-11-17 2002-07-11 Simpson David G. Electroprocessed collagen
AU771015B2 (en) * 1999-03-18 2004-03-11 Celgene Corporation Substituted 1-oxo- and 1,3-dioxoisoindolines and their use in pharmaceutical compositions for reducing inflammatory cytokine levels
AU6679400A (en) 1999-08-27 2001-03-26 Department Of National Defence Hydrogel wound dressing containing liposome-encapsulated therapeutic agent
US6300315B1 (en) * 1999-08-28 2001-10-09 Ceramedical, Inc. Mineralized collagen membrane and method of making same
US6312474B1 (en) * 1999-09-15 2001-11-06 Bio-Vascular, Inc. Resorbable implant materials
US6432712B1 (en) * 1999-11-22 2002-08-13 Bioscience Consultants, Llc Transplantable recellularized and reendothelialized vascular tissue graft
US7004977B2 (en) 1999-11-24 2006-02-28 A Enterprises, Inc. Soft tissue substitute and method of soft tissue reformation
US6428802B1 (en) * 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
US6479064B1 (en) * 1999-12-29 2002-11-12 Children's Medical Center Corporation Culturing different cell populations on a decellularized natural biostructure for organ reconstruction
US6376244B1 (en) * 1999-12-29 2002-04-23 Children's Medical Center Corporation Methods and compositions for organ decellularization
US6866686B2 (en) * 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
US20010038848A1 (en) * 2000-02-18 2001-11-08 Donda Russell S. Implantable tissues infused with growth factors and other additives
ES2238992T3 (es) 2000-03-09 2005-09-16 Syntacoll Ag Matriz de colageno de multiples capas para la reconstruccion de tejido.
GB2360789A (en) 2000-03-30 2001-10-03 Christopher Mason Method of producing tissue structures
JP2004512062A (ja) 2000-07-28 2004-04-22 エモリー ユニバーシテイ 人工膜から成る生物学的構成要素
DE60121450T2 (de) * 2000-08-16 2007-02-15 Duke University Mittels gewebetechnologie hergestellte dezellularisierte gegenstände und gewebe
US6432210B1 (en) * 2000-08-31 2002-08-13 The Ford Meter Box Company, Inc. Method for treating brass
AU9109201A (en) * 2000-09-18 2002-03-26 Organogenesis Inc Methods for treating a patient using a bioengineered flat sheet graft prostheses
JP2002142758A (ja) * 2000-11-09 2002-05-21 Sumitomo Bakelite Co Ltd 培養基質及び培養器
US6458810B1 (en) * 2000-11-14 2002-10-01 George Muller Pharmaceutically active isoindoline derivatives
IL139708A0 (en) * 2000-11-15 2002-02-10 Amiel Gilad Process of decellularizing biological matrices and acellular biological matrices useful in tissue engineering
EP2322601A1 (en) 2000-12-06 2011-05-18 Anthrogenesis Corporation Method of collecting placental stem cells
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
US7091353B2 (en) * 2000-12-27 2006-08-15 Celgene Corporation Isoindole-imide compounds, compositions, and uses thereof
US20030045552A1 (en) 2000-12-27 2003-03-06 Robarge Michael J. Isoindole-imide compounds, compositions, and uses thereof
IL157350A0 (en) 2001-02-14 2004-02-19 Anthrogenesis Corp Post-partum mammalian placenta, its use and placental stem cells therefrom
WO2002067812A2 (en) * 2001-02-23 2002-09-06 University Of Massachusetts Tympanic membrane patch
US6933103B1 (en) * 2001-03-21 2005-08-23 Brennen Medical, Inc. Biocompatible tissue for therapeutic use and method of making same
WO2002102831A1 (en) * 2001-06-14 2002-12-27 Queensland Bioprocessing Technology Pty Ltd. Process for extracting collagen from marine invertebrates
JP5024694B2 (ja) 2001-06-21 2012-09-12 株式会社ビーエムジー 放射線滅菌可能な医用材料及びその用途
AU2002335683B2 (en) 2001-08-31 2008-11-20 Orthopeutics L.P. Use of non-toxic crosslinking reagents to improve fatigue resistance and reduce mechanical degradation of intervertebral disc and other collagenous tissues
US7067492B2 (en) 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
CA2463850C (en) * 2001-10-18 2013-03-26 Lifecell Corporation Remodeling of tissues and organs
US20030187515A1 (en) * 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
KR20050000400A (ko) 2002-04-12 2005-01-03 셀진 코포레이션 줄기 및 전구 세포 분화의 조절, 측정 및 이들의 용도
US7498171B2 (en) 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
EP1525308A4 (en) * 2002-05-30 2006-11-02 Celgene Corp METHODS OF USING JNK OR MKK INHIBITORS TO MODULATE CELL DIFFERENTIATION AND TREAT MYELOPROLIFERATIVE DISORDERS AND MYELODYSPLASIC SYNDROMES
GB2414990B (en) * 2003-02-21 2007-05-23 Uab Research Foundation Biologically active native biomatrix composition
UA83504C2 (en) * 2003-09-04 2008-07-25 Селджин Корпорейшн Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
US7244759B2 (en) * 2004-07-28 2007-07-17 Celgene Corporation Isoindoline compounds and methods of making and using the same
GB0420091D0 (en) * 2004-09-10 2004-10-13 Univ Nottingham Trent Medical implant materials
US20060171930A1 (en) * 2004-12-21 2006-08-03 Agnieszka Seyda Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same
WO2006071777A2 (en) * 2004-12-23 2006-07-06 Ethicon Incorporated Soft tissue repair and regeneration using postpartum-derived cells and cell products
EP1856246B1 (en) * 2005-03-07 2015-07-15 Technion Research & Development Foundation Limited Natural tissue-derived decellularized matrix and methods of generating and using same
WO2006135843A2 (en) * 2005-06-10 2006-12-21 Celgene Corporation Human placental collagen compositions, processes for their preparation, methods of their use and kits comprising the compositions
AU2006265601A1 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
EP1919365A2 (en) * 2005-07-13 2008-05-14 Anthrogenesis Corporation Ocular plug formed from placenta derived collagen biofabric
EP1919500A2 (en) * 2005-07-13 2008-05-14 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
SI1948259T1 (sl) * 2005-10-26 2017-07-31 Genesis Technologies Limited Acelularni bioabsorbljivi tkivni regeneracijski matriksi, proizvedeni z inkubiranjem acelularnih proizvodov krvi
WO2007146123A2 (en) * 2006-06-09 2007-12-21 Anthrogenesis Corporation Placental niche and use thereof to culture stem cells
KR101595108B1 (ko) * 2006-10-06 2016-02-18 안트로제네시스 코포레이션 천연(텔로펩티드) 태반 콜라겐 조성물
JP5056987B2 (ja) 2009-10-16 2012-10-24 富士通株式会社 電子装置

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