BR112017003905A2 - composições da matriz extracelular - Google Patents

composições da matriz extracelular

Info

Publication number
BR112017003905A2
BR112017003905A2 BR112017003905A BR112017003905A BR112017003905A2 BR 112017003905 A2 BR112017003905 A2 BR 112017003905A2 BR 112017003905 A BR112017003905 A BR 112017003905A BR 112017003905 A BR112017003905 A BR 112017003905A BR 112017003905 A2 BR112017003905 A2 BR 112017003905A2
Authority
BR
Brazil
Prior art keywords
compositions
extracellular matrix
ecm
elisa
measured
Prior art date
Application number
BR112017003905A
Other languages
English (en)
Inventor
Kaplunovsky Aleksandr
B Bhatia Mohit
Ye Qian
ZAKA Raihana
Herzberg Uri
Original Assignee
Hli Cellular Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hli Cellular Therapeutics Llc filed Critical Hli Cellular Therapeutics Llc
Publication of BR112017003905A2 publication Critical patent/BR112017003905A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

são proporcionadas aqui composições de matriz extracelular placentária (ecm) e métodos de produzir as mesmas. são também aqui proporcionadas as utilizações das composições ecm placentárias aqui proporcionadas. em um aspecto, aqui proporcionado são composições de matriz extracelular (ecm) preparadas utilizando tecido de placenta, por exemplo, tecido de placenta humana. em certas concretizações, as composições ecm aqui proporcionadas compreendem cerca de 30% a cerca de 60% de colágeno e cerca de 10% a cerca de 35% de elastina. além disso, tais composições ecm compreendem (i) quantidades muito baixas de fibronectina (por exemplo, menos de 0,1% de fibronectina), p.e., tal como medido por elisa; (ii) nenhum ou uma quantidade indetectável de laminina, p. e, como medida por elisa; e / ou nenhum ou uma quantidade indetectável de glicosaminoglicanos, p.e., tal como medido por elisa.
BR112017003905A 2014-08-25 2015-08-25 composições da matriz extracelular BR112017003905A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462041468P 2014-08-25 2014-08-25
PCT/US2015/046690 WO2016033041A1 (en) 2014-08-25 2015-08-25 Extracellular matrix compositions

Publications (1)

Publication Number Publication Date
BR112017003905A2 true BR112017003905A2 (pt) 2018-03-06

Family

ID=55400430

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017003905A BR112017003905A2 (pt) 2014-08-25 2015-08-25 composições da matriz extracelular

Country Status (16)

Country Link
US (1) US20170056479A1 (pt)
EP (1) EP3185888B1 (pt)
JP (3) JP2017525732A (pt)
KR (2) KR20170040809A (pt)
CN (1) CN106794227B (pt)
AU (2) AU2015306811A1 (pt)
BR (1) BR112017003905A2 (pt)
CA (1) CA2958211C (pt)
EA (1) EA201790461A1 (pt)
IL (1) IL250753A0 (pt)
MX (1) MX2017002469A (pt)
MY (1) MY193650A (pt)
NZ (1) NZ729021A (pt)
SG (2) SG11201701114UA (pt)
WO (1) WO2016033041A1 (pt)
ZA (1) ZA201701059B (pt)

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WO2015080901A1 (en) 2013-11-26 2015-06-04 Celleration Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
JP6712160B2 (ja) * 2016-03-29 2020-06-17 株式会社Adeka エンドトキシン測定のための前処理方法及びその測定方法
US11318168B2 (en) 2016-06-24 2022-05-03 Osiris Therapeutics, Inc. Human tissue derived compositions and uses thereof
EP3490673A4 (en) * 2016-07-29 2020-07-22 Alliqua Biomedical, Inc. SYSTEMS AND METHODS FOR DELIVERING CELLULAR AND BIOLOGICAL MATERIALS USING ULTRASONICS FOR THE TREATMENT AND HEALING OF WOUNDS
CN107349463A (zh) * 2017-06-16 2017-11-17 卓阮医疗科技(苏州)有限公司 一种生物源性止血微粒及其制备方法
US11026980B1 (en) * 2018-02-26 2021-06-08 Triad Life Sciences, Inc. Flowable birth tissue composition and related methods
CN109125799A (zh) * 2018-09-05 2019-01-04 张强 GelMA水凝胶人脱细胞羊膜三维双层辅料的制备方法
CN110841115A (zh) * 2019-11-13 2020-02-28 中国科学院遗传与发育生物学研究所 一种胶原凝胶支架及其在提高自体脂肪细胞移植存活率中的应用
CN116600833A (zh) * 2020-05-26 2023-08-15 康维德公司 修饰猪支架及其制备方法
JP7189468B2 (ja) 2021-01-08 2022-12-14 ダイキン工業株式会社 不具合箇所推定システム、不具合箇所推定方法、及びプログラム

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US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
CN1478547A (zh) * 2002-08-28 2004-03-03 赵晓红 胶原蛋白保健胶囊
AU2005322068B2 (en) * 2004-12-23 2011-09-01 Ethicon Incorporated Treatment of stroke and other acute neural degenerative disorders using postpartum derived cells
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US8652500B2 (en) * 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
ES2768968T3 (es) * 2009-08-25 2020-06-24 Tissue Tech Inc Productos de la membrana amniótica del cordón umbilical
US9908691B2 (en) * 2010-06-30 2018-03-06 Gpcp Ip Holdings Llc Dispenser and sheet product dispensing plate therefor
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US20120189586A1 (en) * 2011-01-21 2012-07-26 Carl Randall Harrell Human Placental Derived Extracellular Matrix and Uses Therof
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Also Published As

Publication number Publication date
KR20170040809A (ko) 2017-04-13
IL250753A0 (en) 2017-04-30
CA2958211C (en) 2023-09-26
CN106794227B (zh) 2022-03-01
EA201790461A1 (ru) 2017-07-31
WO2016033041A1 (en) 2016-03-03
JP2017525732A (ja) 2017-09-07
MX2017002469A (es) 2017-05-19
CN106794227A (zh) 2017-05-31
NZ729021A (en) 2022-12-23
JP2022130466A (ja) 2022-09-06
SG11201701114UA (en) 2017-03-30
AU2021202201A1 (en) 2021-05-06
MY193650A (en) 2022-10-21
ZA201701059B (en) 2018-04-25
EP3185888B1 (en) 2023-06-07
SG10201901713RA (en) 2019-03-28
CA2958211A1 (en) 2016-03-03
US20170056479A1 (en) 2017-03-02
EP3185888A4 (en) 2018-06-20
KR20230129618A (ko) 2023-09-08
EP3185888A1 (en) 2017-07-05
AU2015306811A1 (en) 2017-03-09
JP2020142114A (ja) 2020-09-10

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]