MX2012000110A - Metodo para producir eritrocitos sin celulas alimetadoras. - Google Patents

Metodo para producir eritrocitos sin celulas alimetadoras.

Info

Publication number
MX2012000110A
MX2012000110A MX2012000110A MX2012000110A MX2012000110A MX 2012000110 A MX2012000110 A MX 2012000110A MX 2012000110 A MX2012000110 A MX 2012000110A MX 2012000110 A MX2012000110 A MX 2012000110A MX 2012000110 A MX2012000110 A MX 2012000110A
Authority
MX
Mexico
Prior art keywords
hematopoietic cells
erythrocytes
feeder cells
producing erythrocytes
producing
Prior art date
Application number
MX2012000110A
Other languages
English (en)
Inventor
Xiaokui Zhang
Vanessa Voskinarian-Berse
Stewart Abbot
Lin Kang
Original Assignee
Anthrogenesis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anthrogenesis Corp filed Critical Anthrogenesis Corp
Publication of MX2012000110A publication Critical patent/MX2012000110A/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0641—Erythrocytes
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/14—Erythropoietin [EPO]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/145—Thrombopoietin [TPO]
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/90—Polysaccharides
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    • C12N2501/998—Proteins not provided for elsewhere
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se proporcionan en la presente métodos para producir eritrocitos a partir de células hematopoyéticas, particularmente células hematopoyéticas de perfusados de placenta en combinación con células hematopoyéticas de la sangre del cordón umbilical, en donde el método resulta en la expansión y diferenciación aceleradas de las células hematopoyéticas para producir más eficientemente los eritrocitos administrables. Además se proporciona aquí un bioreactor en el cual tiene lugar la expansión y diferenciación de las células hematopoyéticas.
MX2012000110A 2009-07-02 2010-07-01 Metodo para producir eritrocitos sin celulas alimetadoras. MX2012000110A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22293009P 2009-07-02 2009-07-02
PCT/US2010/040707 WO2011002959A1 (en) 2009-07-02 2010-07-01 Method of producing erythrocytes without feeder cells

Publications (1)

Publication Number Publication Date
MX2012000110A true MX2012000110A (es) 2012-04-02

Family

ID=42537451

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012000110A MX2012000110A (es) 2009-07-02 2010-07-01 Metodo para producir eritrocitos sin celulas alimetadoras.
MX2013012849A MX353489B (es) 2009-07-02 2010-07-01 Metodo para producir eritrocitos sin celulas alimentadoras.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2013012849A MX353489B (es) 2009-07-02 2010-07-01 Metodo para producir eritrocitos sin celulas alimentadoras.

Country Status (11)

Country Link
US (3) US8586360B2 (es)
EP (2) EP2449095A1 (es)
JP (6) JP2012531916A (es)
AR (2) AR077369A1 (es)
AU (5) AU2010266263B2 (es)
CA (1) CA2767014C (es)
IL (2) IL217257A (es)
MX (2) MX2012000110A (es)
NZ (2) NZ619359A (es)
WO (1) WO2011002959A1 (es)
ZA (2) ZA201200031B (es)

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