WO2009005151A1 - 新規脂質ペプチド並びにヒドロゲル - Google Patents

新規脂質ペプチド並びにヒドロゲル Download PDF

Info

Publication number
WO2009005151A1
WO2009005151A1 PCT/JP2008/062212 JP2008062212W WO2009005151A1 WO 2009005151 A1 WO2009005151 A1 WO 2009005151A1 JP 2008062212 W JP2008062212 W JP 2008062212W WO 2009005151 A1 WO2009005151 A1 WO 2009005151A1
Authority
WO
WIPO (PCT)
Prior art keywords
group
hydrogel
lipid peptide
carbon atoms
disclosed
Prior art date
Application number
PCT/JP2008/062212
Other languages
English (en)
French (fr)
Inventor
Nobuhide Miyaji
Takehisa Iwama
Masahiro Gotoh
Tatsuo Maruyama
Daisuke Kohda
Original Assignee
Nissan Chemical Industries, Ltd.
Kyushu University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Industries, Ltd., Kyushu University filed Critical Nissan Chemical Industries, Ltd.
Priority to CN200880023439.9A priority Critical patent/CN101809028B/zh
Priority to US12/452,473 priority patent/US8916682B2/en
Priority to JP2009521681A priority patent/JP5441693B2/ja
Priority to EP08790893.5A priority patent/EP2172475B1/en
Publication of WO2009005151A1 publication Critical patent/WO2009005151A1/ja
Priority to US13/685,565 priority patent/US8816049B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

【課題】酸性からアルカリ性の液性範囲において極めて少量でヒドロゲルを形成できる脂質ペプチド並びに高い環境・生体適合性及び生分解性を有するヒドロゲルの提供。 【解決手段】式（１）： （式中、Ｒ1は炭素原子数９乃至２３の脂肪族基を表し、Ｒ2、Ｒ3、Ｒ4及びＲ5は、それぞれ独立して、水素原子、炭素原子数１乃至３の分枝鎖を有し得る炭素原子数１乃至７のアルキル基、フェニルメチル基、フェニルエチル基、又は－（ＣＨ2）ｎ－Ｘ基を表し、且つＲ2、Ｒ3、Ｒ4又はＲ5のうち少なくとも一つが－（ＣＨ2）ｎ－Ｘ基を表し、ｎは１乃至４の数を表し、Ｘはアミノ基、グアニジノ基、－ＣＯＮＨ2基、又は窒素原子を１乃至３個有し得る５員環若しくは６員環又は５員環と６員環から構成される縮合複素環を表し、ｍは１又は２を表す。）で表される脂質ペプチド及びそれからなるヒドロゲル。
PCT/JP2008/062212 2007-07-05 2008-07-04 新規脂質ペプチド並びにヒドロゲル WO2009005151A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN200880023439.9A CN101809028B (zh) 2007-07-05 2008-07-04 新型脂质肽和水凝胶
US12/452,473 US8916682B2 (en) 2007-07-05 2008-07-04 Lipid peptide and hydrogel
JP2009521681A JP5441693B2 (ja) 2007-07-05 2008-07-04 新規脂質ペプチド並びにヒドロゲル
EP08790893.5A EP2172475B1 (en) 2007-07-05 2008-07-04 Lipid peptide for use as hydrogel
US13/685,565 US8816049B2 (en) 2007-07-05 2012-11-26 Lipid peptide and hydrogel

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007177538 2007-07-05
JP2007-177538 2007-07-05

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/452,473 A-371-Of-International US8916682B2 (en) 2007-07-05 2008-07-04 Lipid peptide and hydrogel
US13/685,565 Division US8816049B2 (en) 2007-07-05 2012-11-26 Lipid peptide and hydrogel

Publications (1)

Publication Number Publication Date
WO2009005151A1 true WO2009005151A1 (ja) 2009-01-08

Family

ID=40226189

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/062212 WO2009005151A1 (ja) 2007-07-05 2008-07-04 新規脂質ペプチド並びにヒドロゲル

Country Status (7)

Country Link
US (2) US8916682B2 (ja)
EP (2) EP2559697B1 (ja)
JP (1) JP5441693B2 (ja)
KR (1) KR101557796B1 (ja)
CN (1) CN101809028B (ja)
TW (1) TWI491617B (ja)
WO (1) WO2009005151A1 (ja)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010106981A1 (ja) 2009-03-16 2010-09-23 日産化学工業株式会社 低分子ゲル化剤からなるスプレー用基材
WO2010147158A1 (ja) * 2009-06-19 2010-12-23 日産化学工業株式会社 低分子ゲル化剤により化合物が内包されたゲル
WO2011027897A1 (ja) 2009-09-07 2011-03-10 日産化学工業株式会社 脂質ペプチド化合物の製造方法
WO2011052613A1 (ja) 2009-10-26 2011-05-05 日産化学工業株式会社 化粧料及び皮膚外用剤、並びに医療用機器
WO2012063947A1 (ja) 2010-11-12 2012-05-18 日産化学工業株式会社 脂質ペプチド型ゲル化剤と高分子化合物とを含有するゲルシート
WO2012133787A1 (ja) * 2011-03-31 2012-10-04 日産化学工業株式会社 化粧料の製造方法、化粧料用ゲルの調製方法及び化粧料原料に配合される高分子増粘剤の使用量を軽減する方法
WO2012144609A1 (ja) 2011-04-22 2012-10-26 日産化学工業株式会社 ヒドロゲル形成材料
WO2013094689A1 (ja) * 2011-12-21 2013-06-27 日産化学工業株式会社 水系リチウムイオン二次電池
WO2014003015A1 (ja) 2012-06-25 2014-01-03 日産化学工業株式会社 分散液及びヒドロゲル形成方法
WO2014054702A1 (ja) 2012-10-03 2014-04-10 日産化学工業株式会社 ヒドロゲル形成材料、プレミックス及びヒドロゲル形成方法
WO2014054699A1 (ja) 2012-10-03 2014-04-10 日産化学工業株式会社 ヒドロゲル形成材料
WO2015005219A1 (ja) 2013-07-09 2015-01-15 日産化学工業株式会社 分散液及びヒドロゲル形成方法
US20150367028A1 (en) * 2010-03-31 2015-12-24 Agency For Science, Technology And Research Amphiphilic linear peptide/peptoid and hydrogel comprising the same
US9687591B2 (en) 2010-03-31 2017-06-27 Agency For Science, Technology And Research Building stratified biomimetic tissues and organs using crosslinked ultrashort peptide hydrogel membranes
US9925307B2 (en) 2010-03-31 2018-03-27 Agency For Science, Technology And Research Crosslinked peptide hydrogels
WO2020230697A1 (ja) * 2019-05-10 2020-11-19 国立大学法人九州大学 脂質ペプチド型ゲル化剤とポリアルキレンオキシドとを含有する高分子複合材料
US11452688B2 (en) 2015-01-28 2022-09-27 Kyushu University Transdermally absorbable base material containing lipid peptide compound

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013054922A1 (ja) * 2011-10-14 2013-04-18 日産化学工業株式会社 ゲル状の固体電解質を備えた金属－空気電池
TWI650140B (zh) * 2013-12-25 2019-02-11 日商日產化學工業股份有限公司 含有脂質肽型化合物之條狀基材
KR20180012773A (ko) * 2015-06-24 2018-02-06 닛산 가가쿠 고교 가부시키 가이샤 지질펩티드형 화합물을 함유하는 스틱상 기재
CN106540339B (zh) * 2016-11-03 2019-04-09 东南大学 一种脂肽自组装凝胶及其制备方法和应用
KR20220009367A (ko) * 2019-05-15 2022-01-24 세키스이가가쿠 고교가부시키가이샤 세포배양용 스캐폴드 재료에 의해 형성된 수지막, 세포배양용 담체 및 세포배양용 용기
CN110204593A (zh) * 2019-05-17 2019-09-06 高邮市宇航化工机械厂 一种生物制药用多肽化合物的制备工艺
CN112587477A (zh) * 2020-12-24 2021-04-02 中科院过程工程研究所南京绿色制造产业创新研究院 一种棕榈酰肽水凝胶及其制备方法和用途

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60214768A (ja) * 1984-04-07 1985-10-28 Fujisawa Pharmaceut Co Ltd オリゴペプチド化合物
JP2002085957A (ja) 2000-09-18 2002-03-26 Honda Motor Co Ltd ハイドロゲル
JP2003327949A (ja) 2002-05-13 2003-11-19 Japan Science & Technology Corp グリコシドアミノ酸誘導体から成るヒドロゲル化剤およびヒドロゲル
WO2003099841A2 (en) * 2001-05-21 2003-12-04 Johnson & Johnson Consumer Companies, Inc. Peptides and the use thereof in darkening the skin
JP2004250797A (ja) 2003-02-18 2004-09-09 Japan Science & Technology Agency 微細中空繊維
WO2005105029A1 (es) * 2004-04-28 2005-11-10 Lipotec, S.A. Uso de péptidos xikvav en preparación de composiciones cosméticas para mejorar la firmeza de la piel mediante el aumento de la adhesión celular

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090763A (en) * 1994-02-28 2000-07-18 Stewart; Howard Franklin Hydrogel soap
US6027711A (en) * 1995-06-07 2000-02-22 Rhomed Incorporated Structurally determined metallo-constructs and applications
US7081442B2 (en) * 2001-05-21 2006-07-25 Johnson & Johnson Consumer Companies, Inc. Composition containing a peptide and a pigment and the use thereof in darkening the skin
US7935331B2 (en) * 2003-12-12 2011-05-03 Johnson & Johnson Consumer Companies, Inc. Vanillin polymers for use in darkening the skin
US8420605B2 (en) * 2005-09-07 2013-04-16 The University Of Strathclyde Hydrogel compositions
KR101557814B1 (ko) * 2007-07-05 2015-10-06 닛산 가가쿠 고교 가부시키 가이샤 신규 지질트리펩티드성 히드로겔화제 및 히드로겔

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60214768A (ja) * 1984-04-07 1985-10-28 Fujisawa Pharmaceut Co Ltd オリゴペプチド化合物
JP2002085957A (ja) 2000-09-18 2002-03-26 Honda Motor Co Ltd ハイドロゲル
WO2003099841A2 (en) * 2001-05-21 2003-12-04 Johnson & Johnson Consumer Companies, Inc. Peptides and the use thereof in darkening the skin
JP2003327949A (ja) 2002-05-13 2003-11-19 Japan Science & Technology Corp グリコシドアミノ酸誘導体から成るヒドロゲル化剤およびヒドロゲル
JP2004250797A (ja) 2003-02-18 2004-09-09 Japan Science & Technology Agency 微細中空繊維
WO2005105029A1 (es) * 2004-04-28 2005-11-10 Lipotec, S.A. Uso de péptidos xikvav en preparación de composiciones cosméticas para mejorar la firmeza de la piel mediante el aumento de la adhesión celular

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
A. AGGELI ET AL., ANGEW. CHEM. INT. ED., vol. 42, 2003, pages 5603 - 5606
INFANTE M.R. ET AL.: "Synthesis and surface activity properties of hydrophobic/hydrophilic peptides", INT. J. PEPTIDE PROTEIN RES., vol. 43, no. 2, 1994, pages 173 - 179, XP008128898 *
JEFFREY D. HARTGERINK; ELIA BENIASH; SAMUEL I. STUPP, SCIENCE, vol. 294, 2001, pages 1684 - 1688
KJELD J. C. VAN BOMMEL ET AL., ANGEW. CHEM. INT. ED., vol. 43, 2004, pages 1663 - 1667
NASTRUZZI C. ET AL.: "Liposomes as carriers for DNA-PNA hybrids", J. CONTROL RELEASE, vol. 68, no. 2, 2000, pages 237 - 249, XP004228954 *
NGUYEN-LE X.K. ET AL.: "Pharmacological heterogeneity of neurotensin receptors: an in vitro study", CAN. J. PHYSIOL. PHARMACOL., vol. 75, no. 6, 1997, pages 547 - 551, XP008128922 *
OHASHI W. ET AL.: "Application of arginine-rich RNA-binding peptides to gene delivery", PEPTIDE SCIENCE, vol. 2000, 2001, pages 241 - 242 *
OZOLS J. ET AL.: "Identification of the NH2-terminal blocking group of NADH-cytochrome b5 reductase as myristic acid and the complete amino acid sequence of the membrane-binding domain", J. BIOL. CHEM., vol. 259, no. 21, 1984, pages 13349 - 13354, XP008128836 *
See also references of EP2172475A4 *
SHINJI MATSUMOTO; ITARU HAMACHI, DOJIN NEWS, 2006, pages 1 - 16
W.A. PEKATA ET AL., SCIENCE, vol. 281, 1998, pages 389

Cited By (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010106981A1 (ja) 2009-03-16 2010-09-23 日産化学工業株式会社 低分子ゲル化剤からなるスプレー用基材
TWI504737B (zh) * 2009-03-16 2015-10-21 Nissan Chemical Ind Ltd 低分子凝膠化劑所成之噴霧用基劑
CN102361951A (zh) * 2009-03-16 2012-02-22 日产化学工业株式会社 包含低分子胶凝剂的喷射用基材
JP5587290B2 (ja) * 2009-03-16 2014-09-10 日産化学工業株式会社 低分子ゲル化剤からなるスプレー用基材
US9333158B2 (en) 2009-03-16 2016-05-10 Nissan Chemical Industries, Ltd. Spray base material including low-molecular gelator
CN102361951B (zh) * 2009-03-16 2015-07-22 日产化学工业株式会社 包含低分子胶凝剂的喷射用基材
KR101736169B1 (ko) * 2009-03-16 2017-05-16 닛산 가가쿠 고교 가부시키 가이샤 저분자 겔화제로 이루어진 스프레이용 기재
JPWO2010106981A1 (ja) * 2009-03-16 2012-09-20 日産化学工業株式会社 低分子ゲル化剤からなるスプレー用基材
WO2010147158A1 (ja) * 2009-06-19 2010-12-23 日産化学工業株式会社 低分子ゲル化剤により化合物が内包されたゲル
JP5727932B2 (ja) * 2009-06-19 2015-06-03 日産化学工業株式会社 低分子ゲル化剤により化合物が内包されたゲル
EP2476691A1 (en) * 2009-09-07 2012-07-18 Nissan Chemical Industries, Ltd. Method for manufacturing a lipidic peptide compound
CN102596986A (zh) * 2009-09-07 2012-07-18 日产化学工业株式会社 脂质肽化合物的制造方法
JP5768976B2 (ja) * 2009-09-07 2015-08-26 日産化学工業株式会社 脂質ペプチド化合物の製造方法
WO2011027897A1 (ja) 2009-09-07 2011-03-10 日産化学工業株式会社 脂質ペプチド化合物の製造方法
TWI570132B (zh) * 2009-09-07 2017-02-11 日產化學工業股份有限公司 脂質肽化合物的製造方法
US20120253012A1 (en) * 2009-09-07 2012-10-04 Nissan Chemical Industries, Ltd. Method for preparing lipopeptide compound
US9180201B2 (en) 2009-09-07 2015-11-10 Nissan Chemical Industries, Ltd. Method for preparing lipopeptide compound
KR101754793B1 (ko) 2009-09-07 2017-07-06 닛산 가가쿠 고교 가부시키 가이샤 지질 펩티드 화합물의 제조방법
EP2476691A4 (en) * 2009-09-07 2014-05-07 Nissan Chemical Ind Ltd METHOD FOR MANUFACTURING LIPID PEPTIDE COMPOUND
EP2664321A2 (en) 2009-10-26 2013-11-20 Nissan Chemical Industries, Ltd. Medical instrument
CN105664223A (zh) * 2009-10-26 2016-06-15 日产化学工业株式会社 化妆料、皮肤外用剂、以及医疗用仪器
CN102596164B (zh) * 2009-10-26 2016-08-03 日产化学工业株式会社 化妆料、皮肤外用剂、以及医疗用仪器
US9561255B2 (en) 2009-10-26 2017-02-07 Nissan Chemical Industries, Ltd. Cosmetic, external skin preparation, and medical instrument
WO2011052613A1 (ja) 2009-10-26 2011-05-05 日産化学工業株式会社 化粧料及び皮膚外用剤、並びに医療用機器
US8999300B2 (en) 2009-10-26 2015-04-07 Nissan Chemical Industries Ltd. Cosmetic, external skin preparation, and medical instrument
JP5700222B2 (ja) * 2009-10-26 2015-04-15 日産化学工業株式会社 化粧料及び皮膚外用剤、並びに医療用機器
JP2012213657A (ja) * 2009-10-26 2012-11-08 Nissan Chem Ind Ltd 医療用機器
CN102596164A (zh) * 2009-10-26 2012-07-18 日产化学工业株式会社 化妆料、皮肤外用剂、以及医疗用仪器
US9687591B2 (en) 2010-03-31 2017-06-27 Agency For Science, Technology And Research Building stratified biomimetic tissues and organs using crosslinked ultrashort peptide hydrogel membranes
US10286111B2 (en) 2010-03-31 2019-05-14 Agency For Science, Technology And Research Crosslinked peptide hydrogels
US9925307B2 (en) 2010-03-31 2018-03-27 Agency For Science, Technology And Research Crosslinked peptide hydrogels
US10071183B2 (en) * 2010-03-31 2018-09-11 Agency For Science, Technology And Research Amphiphilic linear peptide/peptoid and hydrogel comprising the same
US10286110B2 (en) 2010-03-31 2019-05-14 Agency For Science, Technology And Research Crosslinked peptide hydrogels
US20150367028A1 (en) * 2010-03-31 2015-12-24 Agency For Science, Technology And Research Amphiphilic linear peptide/peptoid and hydrogel comprising the same
US10293083B2 (en) 2010-03-31 2019-05-21 Agency For Science, Technology And Research Crosslinked peptide hydrogels
JP5904949B2 (ja) * 2010-11-12 2016-04-20 日産化学工業株式会社 脂質ペプチド型ゲル化剤と高分子化合物とを含有するゲルシート
KR101847385B1 (ko) 2010-11-12 2018-04-10 닛산 가가쿠 고교 가부시키 가이샤 지질 펩티드형 겔화제와 고분자 화합물을 함유하는 겔시트
US9480772B2 (en) 2010-11-12 2016-11-01 Nissan Chemical Industries, Ltd. Gel sheet containing lipid peptide gelator and polymeric compound
WO2012063947A1 (ja) 2010-11-12 2012-05-18 日産化学工業株式会社 脂質ペプチド型ゲル化剤と高分子化合物とを含有するゲルシート
WO2012133787A1 (ja) * 2011-03-31 2012-10-04 日産化学工業株式会社 化粧料の製造方法、化粧料用ゲルの調製方法及び化粧料原料に配合される高分子増粘剤の使用量を軽減する方法
US9566218B2 (en) 2011-03-31 2017-02-14 Nissan Chemical Industries, Ltd. Production method of cosmetic, preparation method of gel for cosmetics, and method of reducing use amount of polymer thickener blended in cosmetic raw materials
JP5971487B2 (ja) * 2011-03-31 2016-08-17 日産化学工業株式会社 化粧料の製造方法、化粧料用ゲルの調製方法及び化粧料原料に配合される高分子増粘剤の使用量を軽減する方法
JP5943211B2 (ja) * 2011-04-22 2016-06-29 日産化学工業株式会社 ヒドロゲル形成材料
KR20140039200A (ko) 2011-04-22 2014-04-01 닛산 가가쿠 고교 가부시키 가이샤 하이드로겔 형성 재료
US9328137B2 (en) 2011-04-22 2016-05-03 Nissan Chemical Industries, Ltd. Hydrogel-forming material
WO2012144609A1 (ja) 2011-04-22 2012-10-26 日産化学工業株式会社 ヒドロゲル形成材料
WO2013094689A1 (ja) * 2011-12-21 2013-06-27 日産化学工業株式会社 水系リチウムイオン二次電池
WO2014003015A1 (ja) 2012-06-25 2014-01-03 日産化学工業株式会社 分散液及びヒドロゲル形成方法
EP3296013A1 (en) 2012-06-25 2018-03-21 Nissan Chemical Industries, Ltd. Dispersion and method for forming hydrogel
US10421055B2 (en) 2012-06-25 2019-09-24 Nissan Chemical Industries, Ltd. Dispersion and method for forming hydrogel
KR20150024916A (ko) 2012-06-25 2015-03-09 닛산 가가쿠 고교 가부시키 가이샤 분산액 및 하이드로겔 형성방법
KR102091794B1 (ko) 2012-06-25 2020-03-20 닛산 가가쿠 가부시키가이샤 분산액 및 하이드로겔 형성방법
WO2014054702A1 (ja) 2012-10-03 2014-04-10 日産化学工業株式会社 ヒドロゲル形成材料、プレミックス及びヒドロゲル形成方法
KR20150063151A (ko) 2012-10-03 2015-06-08 닛산 가가쿠 고교 가부시키 가이샤 하이드로겔 형성재료
US9872907B2 (en) 2012-10-03 2018-01-23 Nissan Chemical Industries, Ltd. Hydrogel-forming material, premix, and hydrogel formation method
US9597270B2 (en) 2012-10-03 2017-03-21 Nissan Chemical Industries, Ltd. Hydrogel-forming material
WO2014054699A1 (ja) 2012-10-03 2014-04-10 日産化学工業株式会社 ヒドロゲル形成材料
KR20150064183A (ko) 2012-10-03 2015-06-10 닛산 가가쿠 고교 가부시키 가이샤 하이드로겔 형성재료, 프리믹스 및 하이드로겔 형성방법
US10105294B2 (en) 2013-07-09 2018-10-23 Nissan Chemical Industries, Ltd. Dispersion and method for forming hydrogel
JPWO2015005219A1 (ja) * 2013-07-09 2017-03-02 日産化学工業株式会社 分散液及びヒドロゲル形成方法
KR20160029807A (ko) 2013-07-09 2016-03-15 닛산 가가쿠 고교 가부시키 가이샤 분산액 및 하이드로겔 형성방법
WO2015005219A1 (ja) 2013-07-09 2015-01-15 日産化学工業株式会社 分散液及びヒドロゲル形成方法
US9782331B2 (en) 2013-07-09 2017-10-10 Nissan Chemical Industries, Ltd. Dispersion and method for forming hydrogel
US11452688B2 (en) 2015-01-28 2022-09-27 Kyushu University Transdermally absorbable base material containing lipid peptide compound
US11771645B2 (en) 2015-01-28 2023-10-03 Kyushu University Transdermally absorbable base material containing lipid peptide compound
WO2020230697A1 (ja) * 2019-05-10 2020-11-19 国立大学法人九州大学 脂質ペプチド型ゲル化剤とポリアルキレンオキシドとを含有する高分子複合材料

Also Published As

Publication number Publication date
EP2559697A1 (en) 2013-02-20
US8916682B2 (en) 2014-12-23
KR101557796B1 (ko) 2015-10-06
TWI491617B (zh) 2015-07-11
EP2559697B1 (en) 2014-03-26
EP2172475A1 (en) 2010-04-07
TW200916483A (en) 2009-04-16
JPWO2009005151A1 (ja) 2010-08-26
KR20100058454A (ko) 2010-06-03
US8816049B2 (en) 2014-08-26
US20130144037A1 (en) 2013-06-06
EP2172475A4 (en) 2010-09-15
JP5441693B2 (ja) 2014-03-12
US20100291210A1 (en) 2010-11-18
EP2172475B1 (en) 2015-06-03
CN101809028A (zh) 2010-08-18
CN101809028B (zh) 2015-11-25

Similar Documents

Publication Publication Date Title
WO2009005151A1 (ja) 新規脂質ペプチド並びにヒドロゲル
WO2009005152A1 (ja) 新規脂質トリペプチド性ヒドロゲル化剤及びヒドロゲル
TW200624539A (en) Optical film
MX2009010024A (es) Nuevo compuesto de adenina.
DK1325910T3 (da) Aliphatiske nitrogenholdige femleddede ringforbindelser
TW200642683A (en) Heterocyclic compound
WO2008114819A1 (ja) 新規アデニン化合物
MX2010002266A (es) Derivados de pirazol sustituidos.
TW200744659A (en) Preparation for preventing and ameliorating wrinkle
WO2008108256A1 (ja) 発光素子材料および発光素子
EP1719761A4 (en) NEW HETEROCYCLIC CONNECTION
TW200722432A (en) Thiazole compounds
WO2008136444A1 (ja) 縮合複素環誘導体
MX2010001344A (es) Compuesto de acido fenilacetico.
MY183326A (en) New dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them
WO2008105138A1 (ja) ポリチオウレタン系光学材料用重合触媒、それを含む重合性組成物、それより得られる光学材料、およびその製造方法
WO2008149834A1 (ja) ピリミドジアゼピノン誘導体
WO2009005135A1 (ja) エポキシ樹脂用硬化剤及びエポキシ樹脂用硬化剤組成物
IN2015KN00276A (ja)
TW200745153A (en) Trehalose compound and pharmaceutical comprising the compound
MX2010010471A (es) Derivado de tetrahidroisoquinolina novedoso.
MY149301A (en) Epoxy compound and method for manufacturing the same
EP1864977A4 (en) NOVEL CYCLIC COMPOUNDS HAVING A PYRIMIDINYLALKYLTHIO GROUP
WO2008149701A1 (ja) 感放射線性樹脂組成物
TW200609206A (en) Agent for permanent hair processing

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880023439.9

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08790893

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009521681

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008790893

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 20107002123

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 12452473

Country of ref document: US