WO2008139965A1 - 新規なビタミンｂ６誘導体 - Google Patents

新規なビタミンｂ６誘導体 Download PDF

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Publication number
WO2008139965A1
WO2008139965A1 PCT/JP2008/058398 JP2008058398W WO2008139965A1 WO 2008139965 A1 WO2008139965 A1 WO 2008139965A1 JP 2008058398 W JP2008058398 W JP 2008058398W WO 2008139965 A1 WO2008139965 A1 WO 2008139965A1
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WO
WIPO (PCT)
Prior art keywords
group
derivative
formula
phosphate
vitamin
Prior art date
Application number
PCT/JP2008/058398
Other languages
English (en)
French (fr)
Inventor
Keiji Sakamoto
Koichi Wada
Hajime Ito
Kazuya Hongo
Original Assignee
Daiichi Fine Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Fine Chemical Co., Ltd. filed Critical Daiichi Fine Chemical Co., Ltd.
Publication of WO2008139965A1 publication Critical patent/WO2008139965A1/ja

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/6574—Esters of oxyacids of phosphorus
    • C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

　光安定性を有し、かつ適度な水溶性及び脂溶性を兼ね備えたビタミンＢ６誘導体である下記の一般式（Ｉ）： [R1はグリコシル基又はリン酸基を示し、R2は－CH2OH、-CHO、－CH2NH2、-CH2O-CO-A(AはC3-C15アルキル基、アリール基、又はアリール(C1-C6)アルキレン基を示す)で表される基、-CH2NH-CO-B(BはA又は-O-Aを示す)で表される基、又は-CH2O-リン酸を示し、R3は水素原子、リン酸基、又は-CO-Aで表される基を示す]で表される化合物又はその塩。
PCT/JP2008/058398 2007-05-07 2008-05-02 新規なビタミンｂ６誘導体 WO2008139965A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-122611 2007-05-07
JP2007122611 2007-05-07

Publications (1)

Publication Number Publication Date
WO2008139965A1 true WO2008139965A1 (ja) 2008-11-20

Family

ID=40002172

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/058398 WO2008139965A1 (ja) 2007-05-07 2008-05-02 新規なビタミンｂ６誘導体

Country Status (1)

Country Link
WO (1) WO2008139965A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104418892A (zh) * 2013-08-28 2015-03-18 江西天新药业有限公司 一种吡哆醇环磷酸衍生物及其制备方法和应用
CN104414871A (zh) * 2013-08-28 2015-03-18 江西天新药业有限公司 一种化妆品组合物及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003206279A (ja) * 2002-01-08 2003-07-22 Nikko Chemical Co Ltd ピリドキシン誘導体、及び該ピリドキシン誘導体を含有する皮膚化粧料、及び頭髪化粧料
WO2005033123A1 (ja) * 2003-10-01 2005-04-14 Daiichi Fine Chemical Co., Ltd. 安定なビタミンｂ６誘導体

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003206279A (ja) * 2002-01-08 2003-07-22 Nikko Chemical Co Ltd ピリドキシン誘導体、及び該ピリドキシン誘導体を含有する皮膚化粧料、及び頭髪化粧料
WO2005033123A1 (ja) * 2003-10-01 2005-04-14 Daiichi Fine Chemical Co., Ltd. 安定なビタミンｂ６誘導体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANDON M.B. ET AL.: "Dietary intake of total and glycosylated vitamin B6 and the vitamin B6 nutritional status of unsupplemented lactating women and their infants", AMERICAN JOURNAL OF CLINICAL NUTRITION, vol. 50, no. 5, 1989, pages 1050 - 1058 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104418892A (zh) * 2013-08-28 2015-03-18 江西天新药业有限公司 一种吡哆醇环磷酸衍生物及其制备方法和应用
CN104414871A (zh) * 2013-08-28 2015-03-18 江西天新药业有限公司 一种化妆品组合物及其应用

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