UA107457C2 - Похідні піразолу - Google Patents

Похідні піразолу

Info

Publication number
UA107457C2
UA107457C2 UAA201112488A UAA201112488A UA107457C2 UA 107457 C2 UA107457 C2 UA 107457C2 UA A201112488 A UAA201112488 A UA A201112488A UA A201112488 A UAA201112488 A UA A201112488A UA 107457 C2 UA107457 C2 UA 107457C2
Authority
UA
Ukraine
Prior art keywords
hydrogen atom
halogen atom
substituent
pyrazole derivatives
atom
Prior art date
Application number
UAA201112488A
Other languages
English (en)
Russian (ru)
Inventor
Харуюкі Нішіда
Ікуо Фуджіморі
Original Assignee
Такеда Фармасьютікал Компані Лімітед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Такеда Фармасьютікал Компані Лімітед filed Critical Такеда Фармасьютікал Компані Лімітед
Publication of UA107457C2 publication Critical patent/UA107457C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Винахід стосується сполуки, що більш сильно пригнічує секрецію кислоти та має противиразкову дію, тощо. Сполука, представлена формулою EMBED ISISServer , (I) де R1 є замісником, R2 означає (і) атом водню, (іі) С1-6-алкіл, який необов'язково містить атом галогену, або (ііі) ціаногрупу, R3 означає (і) атом водню, (іі) атом галогену, (ііі) ціаногрупу, (iv) С1-6-алкіл, який необов'язково містить атом галогену, або (v) С1-6-алкокси, який необов'язково містить атом галогену, один з R2 та R3 означає атом водню та інший є замісником, що не є атомом водню, або її сіль.
UAA201112488A 2009-03-26 2010-03-25 Похідні піразолу UA107457C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009077078 2009-03-26
PCT/JP2010/055257 WO2010110378A1 (ja) 2009-03-26 2010-03-25 ピラゾール化合物

Publications (1)

Publication Number Publication Date
UA107457C2 true UA107457C2 (uk) 2015-01-12

Family

ID=42781069

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201112488A UA107457C2 (uk) 2009-03-26 2010-03-25 Похідні піразолу

Country Status (25)

Country Link
US (1) US8895588B2 (uk)
EP (1) EP2412713B1 (uk)
JP (1) JP5552481B2 (uk)
KR (1) KR101656906B1 (uk)
CN (1) CN102448953B (uk)
AU (1) AU2010228220B2 (uk)
BR (1) BRPI1009090A2 (uk)
CA (1) CA2756086A1 (uk)
CL (1) CL2011002351A1 (uk)
CO (1) CO6460700A2 (uk)
CR (1) CR20110533A (uk)
DO (1) DOP2011000296A (uk)
EA (1) EA019853B1 (uk)
EC (1) ECSP11011419A (uk)
GE (1) GEP20156222B (uk)
IL (1) IL215235A (uk)
MA (1) MA33214B1 (uk)
MX (1) MX2011009943A (uk)
NZ (1) NZ595890A (uk)
PE (1) PE20120618A1 (uk)
SG (1) SG174476A1 (uk)
TN (1) TN2011000474A1 (uk)
UA (1) UA107457C2 (uk)
WO (1) WO2010110378A1 (uk)
ZA (1) ZA201107435B (uk)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201408511QA (en) 2012-06-27 2015-01-29 Takeda Pharmaceutical Liquid preparations of amines and organic acids stabilized by salts
AU2013323349B2 (en) * 2012-09-27 2016-09-15 Aratana Therapeutics, Inc. Compositions and methods of use of an inappetance-controlling compound
WO2016123233A1 (en) 2015-01-28 2016-08-04 Aratana Therapeutics, Inc. Compositions and methods for chronic use of a weight-gaining compound
CN105067814A (zh) * 2015-07-24 2015-11-18 中国科学院成都生物研究所 解旋酶水解atp活性测定方法

Family Cites Families (21)

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US3285991A (en) 1963-03-26 1966-11-15 Union Carbide Corp Polyepoxides cured with the reaction product of a dihydroxydiphenylsul-fone, an amine, and an aldehyde
US4847289A (en) 1987-06-08 1989-07-11 Merck & Co., Inc. Thiophene sulfonamide antiglaucoma agents
CN1071924A (zh) 1991-10-29 1993-05-12 纳幕尔杜邦公司 除草的三唑羧酸酰胺
JP3155009B2 (ja) 1994-09-26 2001-04-09 塩野義製薬株式会社 イミダゾール誘導体
JPH0948778A (ja) 1995-08-04 1997-02-18 Sagami Chem Res Center ２−置換−３−アルコキシ−５−（ピロール−２−イル）フラン誘導体
ZA969273B (en) 1995-11-06 1998-05-05 Univ Pittsburgh Inhibitors of protein isoprenyl transferases.
ATE443698T1 (de) 1996-12-23 2009-10-15 Bristol Myers Squibb Pharma Co Stickstoffhaltige heterocyclen als faktor xa- hemmer
WO1999042461A1 (en) 1998-02-23 1999-08-26 Warner-Lambert Company Substituted quinoxaline derivatives as interleukin-8 receptor antagonists
US7211590B2 (en) 2002-08-01 2007-05-01 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
JP2006526015A (ja) 2003-05-02 2006-11-16 エラン ファーマシューティカルズ，インコーポレイテッド 炎症疾患治療のためのブラジキニンｂ１受容体アンタゴニストとしての４−ブロモ−５−（２−クロロ−ベンゾイルアミノ）−１ｈ−ピラゾール−３−カルボン酸アミド誘導体および関連化合物
ES2351393T3 (es) 2003-05-26 2011-02-03 Takeda Pharmaceutical Company Limited Sulfopirroles.
EP1648455A4 (en) 2003-07-23 2009-03-04 Exelixis Inc MODULATORS OF ALK PROTEIN (ANAPLASTIC LYMPHOMA KINASE) AND METHODS OF USE
US8048909B2 (en) 2004-09-30 2011-11-01 Takeda Pharmaceutical Company Limited Proton pump inhibitors
JP4035559B1 (ja) * 2005-08-30 2008-01-23 武田薬品工業株式会社 酸分泌抑制薬としての１−ヘテロシクリルスルホニル、２−アミノメチル、５−（ヘテロ−）アリール置換１−ｈ−ピロール誘導体
EP2005957B1 (en) * 2006-03-31 2012-05-30 Takeda Pharmaceutical Company Limited Acid secretion inhibitor
US8933105B2 (en) * 2007-02-28 2015-01-13 Takeda Pharmaceutical Company Limited Pyrrole compounds
JP2009077078A (ja) 2007-09-19 2009-04-09 Brother Ind Ltd 位置検出システム
US20090156642A1 (en) 2007-09-28 2009-06-18 Takeda Pharmaceutical Company Limited 5-Membered heterocyclic compound
WO2009041447A1 (ja) 2007-09-28 2009-04-02 Takeda Pharmaceutical Company Limited ５員複素環化合物
PE20091846A1 (es) 2008-05-19 2009-12-16 Plexxikon Inc DERIVADOS DE PIRROLO[2,3-d]-PIRIMIDINA COMO MODULADORES DE CINASAS
CN102099339A (zh) 2008-07-18 2011-06-15 武田药品工业株式会社 苯并氮杂衍生物及其作为组胺h3拮抗剂的用途

Also Published As

Publication number Publication date
ECSP11011419A (es) 2011-11-30
EP2412713A4 (en) 2014-04-02
NZ595890A (en) 2013-09-27
CN102448953A (zh) 2012-05-09
CR20110533A (es) 2012-02-13
KR101656906B1 (ko) 2016-09-12
CL2011002351A1 (es) 2012-07-13
CA2756086A1 (en) 2010-09-30
IL215235A (en) 2014-07-31
MX2011009943A (es) 2011-10-06
PE20120618A1 (es) 2012-06-05
BRPI1009090A2 (pt) 2016-03-01
GEP20156222B (en) 2015-01-26
EA201171168A1 (ru) 2012-05-30
MA33214B1 (fr) 2012-04-02
SG174476A1 (en) 2011-10-28
AU2010228220B2 (en) 2015-05-21
AU2010228220A1 (en) 2011-11-17
TN2011000474A1 (en) 2013-03-27
JPWO2010110378A1 (ja) 2012-10-04
JP5552481B2 (ja) 2014-07-16
EP2412713A1 (en) 2012-02-01
CN102448953B (zh) 2014-05-07
CO6460700A2 (es) 2012-06-15
EP2412713B1 (en) 2016-11-30
ZA201107435B (en) 2012-08-29
DOP2011000296A (es) 2011-10-15
AU2010228220A2 (en) 2011-11-24
IL215235A0 (en) 2011-12-29
KR20110130483A (ko) 2011-12-05
US8895588B2 (en) 2014-11-25
US20120095057A1 (en) 2012-04-19
WO2010110378A1 (ja) 2010-09-30
EA019853B1 (ru) 2014-06-30

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