UA105185C2 - Піроли - Google Patents

Піроли

Info

Publication number
UA105185C2
UA105185C2 UAA201103600A UAA201103600A UA105185C2 UA 105185 C2 UA105185 C2 UA 105185C2 UA A201103600 A UAA201103600 A UA A201103600A UA A201103600 A UAA201103600 A UA A201103600A UA 105185 C2 UA105185 C2 UA 105185C2
Authority
UA
Ukraine
Prior art keywords
halogen
optionally substituted
group optionally
alkyl group
hydrogen atom
Prior art date
Application number
UAA201103600A
Other languages
English (en)
Russian (ru)
Inventor
Харуюкі Нішіда
Ясуйоші Арікава
Ікуо Фуджіморі
Original Assignee
Такеда Фармасьютікал Компані Лімітед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41508823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA105185(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Такеда Фармасьютікал Компані Лімітед filed Critical Такеда Фармасьютікал Компані Лімітед
Publication of UA105185C2 publication Critical patent/UA105185C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Даний винахід стосується сполуки, представленої формулою: EMBED ISISServer , (I) де А означає піридил, який має щонайменше один замісник EMBED ISISServer (А-1) або EMBED ISISServer , (А-2) де R1, R2 та R3 кожен означає атом водню, атом галогену, С1-6-алкіл, необов'язково заміщений галогеном або С1-6-алкокси, необов'язково заміщений галогеном, R4 та R6 кожен означає атом водню, атом галогену або С1-6-алкіл, необов'язково заміщений галогеном, R5 означає атом водню, атом галогену, С1-6-алкіл, необов'язково заміщений галогеном або С1-6-алкокси, необов'язково заміщений галогеном, та R7 означає атом водню або С1-6-алкіл, необов'язково заміщений галогеном, або її солі або фармацевтичної композиції, яка їх містить.
UAA201103600A 2008-08-27 2009-08-26 Піроли UA105185C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008218851 2008-08-27
JP2008269099 2008-10-17
PCT/JP2009/065279 WO2010024451A1 (en) 2008-08-27 2009-08-26 Pyrrole compounds

Publications (1)

Publication Number Publication Date
UA105185C2 true UA105185C2 (uk) 2014-04-25

Family

ID=41508823

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201103600A UA105185C2 (uk) 2008-08-27 2009-08-26 Піроли

Country Status (39)

Country Link
US (3) US8592597B2 (uk)
EP (1) EP2318390B1 (uk)
JP (1) JP5638515B2 (uk)
KR (1) KR101629181B1 (uk)
CN (1) CN102197033B (uk)
AR (1) AR073136A1 (uk)
AU (1) AU2009284867B2 (uk)
BR (1) BRPI0917705A2 (uk)
CA (1) CA2735162C (uk)
CL (1) CL2011000402A1 (uk)
CO (1) CO6321166A2 (uk)
CR (1) CR20110169A (uk)
CY (1) CY1114452T1 (uk)
DK (1) DK2318390T3 (uk)
DO (1) DOP2011000061A (uk)
EA (1) EA019741B1 (uk)
EC (1) ECSP11010912A (uk)
ES (1) ES2423289T3 (uk)
GE (1) GEP20135786B (uk)
HK (1) HK1157756A1 (uk)
HR (1) HRP20130653T1 (uk)
IL (1) IL211335A (uk)
JO (1) JO2871B1 (uk)
MA (1) MA32647B1 (uk)
ME (1) ME01598B (uk)
MX (1) MX2011001955A (uk)
MY (1) MY152008A (uk)
NZ (1) NZ591793A (uk)
PE (2) PE20110300A1 (uk)
PL (1) PL2318390T3 (uk)
PT (1) PT2318390E (uk)
RS (1) RS52872B (uk)
SI (1) SI2318390T1 (uk)
SM (1) SMT201300085B (uk)
TW (1) TWI473798B (uk)
UA (1) UA105185C2 (uk)
UY (1) UY32074A (uk)
WO (1) WO2010024451A1 (uk)
ZA (1) ZA201101774B (uk)

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WO2014144231A1 (en) 2013-03-15 2014-09-18 Massachusetts Institute Of Technology Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness
KR102084185B1 (ko) * 2013-08-29 2020-03-04 주식회사 대웅제약 테트라히드로사이클로펜타피롤 유도체 및 이의 제조방법
CN105367550A (zh) * 2014-08-11 2016-03-02 江苏柯菲平医药股份有限公司 四氢环戊二烯并[c]吡咯类衍生物、其制备方法及其在医药上的应用
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CN108203430A (zh) * 2016-12-16 2018-06-26 天地人和生物科技有限公司 一种新型可逆性质子泵抑制剂及其制备方法和用途
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CN113527536B (zh) * 2020-04-21 2024-03-22 杭州德柯医疗科技有限公司 一种含氟多糖高分子化合物及其制备方法
JP7404561B2 (ja) * 2020-06-17 2023-12-25 イルドン ファーマシューティカル カンパニー リミテッド 新規な酸分泌抑制剤及びその用途
EP4074317A1 (en) 2021-04-14 2022-10-19 Bayer AG Phosphorus derivatives as novel sos1 inhibitors
CN113620930B (zh) * 2021-07-12 2022-08-16 南京烁慧医药科技有限公司 一种含磺酰胺结构的化合物及其制备方法和应用、一种药物组合物及应用
KR20230091056A (ko) * 2021-12-15 2023-06-22 일동제약(주) 1-설포닐 피롤 유도체의 신규 염, 이의 제조 방법 및 이를 포함하는 약학 조성물
WO2023113474A1 (ko) * 2021-12-15 2023-06-22 일동제약(주) 1-설포닐 피롤 유도체의 신규 염, 이의 제조 방법 및 이를 포함하는 약학 조성물
KR20230102353A (ko) * 2021-12-30 2023-07-07 주식회사 대웅제약 삼중음성유방암의 예방 또는 치료용 약학적 조성물

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Also Published As

Publication number Publication date
UY32074A (es) 2010-03-26
CA2735162A1 (en) 2010-03-04
AR073136A1 (es) 2010-10-13
MA32647B1 (fr) 2011-09-01
CN102197033B (zh) 2014-07-16
IL211335A (en) 2013-12-31
ME01598B (me) 2014-09-20
ZA201101774B (en) 2012-06-27
PT2318390E (pt) 2013-07-10
SI2318390T1 (sl) 2013-08-30
CN102197033A (zh) 2011-09-21
DK2318390T3 (da) 2013-07-08
JO2871B1 (en) 2015-03-15
BRPI0917705A2 (pt) 2016-02-16
ES2423289T3 (es) 2013-09-19
EA201170384A1 (ru) 2011-10-31
SMT201300085B (it) 2013-09-06
US20140031393A1 (en) 2014-01-30
CR20110169A (es) 2011-05-16
RS52872B (en) 2013-12-31
KR101629181B1 (ko) 2016-06-13
PE20110300A1 (es) 2011-06-16
AU2009284867A2 (en) 2011-04-21
TW201010993A (en) 2010-03-16
EP2318390B1 (en) 2013-05-01
US8993598B2 (en) 2015-03-31
CA2735162C (en) 2015-06-23
TWI473798B (zh) 2015-02-21
WO2010024451A1 (en) 2010-03-04
US8592597B2 (en) 2013-11-26
US20100056577A1 (en) 2010-03-04
MX2011001955A (es) 2011-03-29
ECSP11010912A (es) 2011-04-29
HRP20130653T1 (en) 2013-08-31
JP2012501296A (ja) 2012-01-19
EP2318390A1 (en) 2011-05-11
KR20110071067A (ko) 2011-06-28
IL211335A0 (en) 2011-04-28
AU2009284867B2 (en) 2014-08-28
PL2318390T3 (pl) 2013-09-30
US8969387B2 (en) 2015-03-03
GEP20135786B (en) 2013-03-11
PE20141174A1 (es) 2014-09-19
HK1157756A1 (en) 2012-07-06
MY152008A (en) 2014-08-15
NZ591793A (en) 2012-11-30
US20110172275A1 (en) 2011-07-14
CO6321166A2 (es) 2011-09-20
DOP2011000061A (es) 2011-04-15
CY1114452T1 (el) 2016-10-05
EA019741B1 (ru) 2014-05-30
AU2009284867A1 (en) 2010-03-04
CL2011000402A1 (es) 2011-07-29
JP5638515B2 (ja) 2014-12-10

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