EA201170384A1 - Пиррольные соединения - Google Patents

Пиррольные соединения

Info

Publication number
EA201170384A1
EA201170384A1 EA201170384A EA201170384A EA201170384A1 EA 201170384 A1 EA201170384 A1 EA 201170384A1 EA 201170384 A EA201170384 A EA 201170384A EA 201170384 A EA201170384 A EA 201170384A EA 201170384 A1 EA201170384 A1 EA 201170384A1
Authority
EA
Eurasian Patent Office
Prior art keywords
halogen atom
optionally substituted
alkyl group
atom
hydrogen atom
Prior art date
Application number
EA201170384A
Other languages
English (en)
Other versions
EA019741B1 (ru
Inventor
Харуюки Нисида
Ясуеси Арикава
Икуо Фудзимори
Original Assignee
Такеда Фармасьютикал Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41508823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201170384(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Такеда Фармасьютикал Компани Лимитед filed Critical Такеда Фармасьютикал Компани Лимитед
Publication of EA201170384A1 publication Critical patent/EA201170384A1/ru
Publication of EA019741B1 publication Critical patent/EA019741B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Настоящее изобретение относится к соединению, представленному формулойв которой А представляет собой пиридильную группу, содержащую по меньшей мере один заместительгде каждый R, Rи Rпредставляет атом водорода, атом галогена, Cалкильную группу, необязательно замещенную атомом галогена, или Cалкоксигруппу, необязательно замещенную атомом галогена, каждый Rи Rпредставляет атом водорода, атом галогена или Cалкильную группу, необязательно замещенную атомом галогена, Rпредставляет собой атом водорода, атом галогена, Cалкильную группу, необязательно замещенную атомом галогена, или Cалкоксигруппу, необязательно замещенную атомом галогена, и Rпредставляет собой атом водорода или Cалкильную группу, необязательно замещенную атомом галогена, или к его соли, или к содержащей их фармацевтической композиции.
EA201170384A 2008-08-27 2009-08-26 Пиррольные соединения EA019741B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008218851 2008-08-27
JP2008269099 2008-10-17
PCT/JP2009/065279 WO2010024451A1 (en) 2008-08-27 2009-08-26 Pyrrole compounds

Publications (2)

Publication Number Publication Date
EA201170384A1 true EA201170384A1 (ru) 2011-10-31
EA019741B1 EA019741B1 (ru) 2014-05-30

Family

ID=41508823

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170384A EA019741B1 (ru) 2008-08-27 2009-08-26 Пиррольные соединения

Country Status (39)

Country Link
US (3) US8592597B2 (ru)
EP (1) EP2318390B1 (ru)
JP (1) JP5638515B2 (ru)
KR (1) KR101629181B1 (ru)
CN (1) CN102197033B (ru)
AR (1) AR073136A1 (ru)
AU (1) AU2009284867B2 (ru)
BR (1) BRPI0917705A2 (ru)
CA (1) CA2735162C (ru)
CL (1) CL2011000402A1 (ru)
CO (1) CO6321166A2 (ru)
CR (1) CR20110169A (ru)
CY (1) CY1114452T1 (ru)
DK (1) DK2318390T3 (ru)
DO (1) DOP2011000061A (ru)
EA (1) EA019741B1 (ru)
EC (1) ECSP11010912A (ru)
ES (1) ES2423289T3 (ru)
GE (1) GEP20135786B (ru)
HK (1) HK1157756A1 (ru)
HR (1) HRP20130653T1 (ru)
IL (1) IL211335A (ru)
JO (1) JO2871B1 (ru)
MA (1) MA32647B1 (ru)
ME (1) ME01598B (ru)
MX (1) MX2011001955A (ru)
MY (1) MY152008A (ru)
NZ (1) NZ591793A (ru)
PE (2) PE20141174A1 (ru)
PL (1) PL2318390T3 (ru)
PT (1) PT2318390E (ru)
RS (1) RS52872B (ru)
SI (1) SI2318390T1 (ru)
SM (1) SMT201300085B (ru)
TW (1) TWI473798B (ru)
UA (1) UA105185C2 (ru)
UY (1) UY32074A (ru)
WO (1) WO2010024451A1 (ru)
ZA (1) ZA201101774B (ru)

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WO2023113474A1 (ko) * 2021-12-15 2023-06-22 일동제약(주) 1-설포닐 피롤 유도체의 신규 염, 이의 제조 방법 및 이를 포함하는 약학 조성물
KR20230102353A (ko) * 2021-12-30 2023-07-07 주식회사 대웅제약 삼중음성유방암의 예방 또는 치료용 약학적 조성물

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Also Published As

Publication number Publication date
PE20110300A1 (es) 2011-06-16
PL2318390T3 (pl) 2013-09-30
MY152008A (en) 2014-08-15
CA2735162C (en) 2015-06-23
AU2009284867B2 (en) 2014-08-28
BRPI0917705A2 (pt) 2016-02-16
US20100056577A1 (en) 2010-03-04
EP2318390B1 (en) 2013-05-01
ZA201101774B (en) 2012-06-27
HRP20130653T1 (en) 2013-08-31
TW201010993A (en) 2010-03-16
KR20110071067A (ko) 2011-06-28
JO2871B1 (en) 2015-03-15
UA105185C2 (ru) 2014-04-25
SMT201300085B (it) 2013-09-06
IL211335A0 (en) 2011-04-28
US8592597B2 (en) 2013-11-26
JP5638515B2 (ja) 2014-12-10
IL211335A (en) 2013-12-31
TWI473798B (zh) 2015-02-21
DOP2011000061A (es) 2011-04-15
ES2423289T3 (es) 2013-09-19
JP2012501296A (ja) 2012-01-19
UY32074A (es) 2010-03-26
US20110172275A1 (en) 2011-07-14
CO6321166A2 (es) 2011-09-20
KR101629181B1 (ko) 2016-06-13
GEP20135786B (en) 2013-03-11
CN102197033A (zh) 2011-09-21
CN102197033B (zh) 2014-07-16
EA019741B1 (ru) 2014-05-30
AR073136A1 (es) 2010-10-13
AU2009284867A2 (en) 2011-04-21
US8969387B2 (en) 2015-03-03
ECSP11010912A (es) 2011-04-29
RS52872B (en) 2013-12-31
CY1114452T1 (el) 2016-10-05
MA32647B1 (fr) 2011-09-01
CL2011000402A1 (es) 2011-07-29
PT2318390E (pt) 2013-07-10
AU2009284867A1 (en) 2010-03-04
ME01598B (me) 2014-09-20
NZ591793A (en) 2012-11-30
CA2735162A1 (en) 2010-03-04
DK2318390T3 (da) 2013-07-08
SI2318390T1 (sl) 2013-08-30
HK1157756A1 (en) 2012-07-06
CR20110169A (es) 2011-05-16
PE20141174A1 (es) 2014-09-19
MX2011001955A (es) 2011-03-29
US20140031393A1 (en) 2014-01-30
US8993598B2 (en) 2015-03-31
EP2318390A1 (en) 2011-05-11
WO2010024451A1 (en) 2010-03-04

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