UA95267C2 - Heteroaryl substituted benzothiazoles - Google Patents

Heteroaryl substituted benzothiazoles

Info

Publication number
UA95267C2
UA95267C2 UAA200809015A UAA200809015A UA95267C2 UA 95267 C2 UA95267 C2 UA 95267C2 UA A200809015 A UAA200809015 A UA A200809015A UA A200809015 A UAA200809015 A UA A200809015A UA 95267 C2 UA95267 C2 UA 95267C2
Authority
UA
Ukraine
Prior art keywords
heteroaryl substituted
relates
alzheimer
compositions
compounds
Prior art date
Application number
UAA200809015A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Ильва Гравенфорсб
Катрин Джонассонб
Джонес Мальмстрём
Гуннар Нардволл
Девид Пиринг
Кен Сливо
Даниэль Сон
Питер Стрём
Девид Венсбо
Original Assignee
Астразенека Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38309497&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA95267(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Астразенека Аб filed Critical Астразенека Аб
Publication of UA95267C2 publication Critical patent/UA95267C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
UAA200809015A 2006-01-27 2007-01-25 Heteroaryl substituted benzothiazoles UA95267C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76265406P 2006-01-27 2006-01-27

Publications (1)

Publication Number Publication Date
UA95267C2 true UA95267C2 (en) 2011-07-25

Family

ID=38309497

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200809015A UA95267C2 (en) 2006-01-27 2007-01-25 Heteroaryl substituted benzothiazoles

Country Status (20)

Country Link
US (2) US8163928B2 (enExample)
EP (1) EP1981883A4 (enExample)
JP (1) JP5289061B2 (enExample)
KR (1) KR101406248B1 (enExample)
CN (1) CN101410393B (enExample)
AR (1) AR059178A1 (enExample)
AU (1) AU2007207904C1 (enExample)
BR (1) BRPI0707283A2 (enExample)
CA (1) CA2640213A1 (enExample)
EC (1) ECSP088645A (enExample)
IL (1) IL192876A0 (enExample)
NO (1) NO20083394L (enExample)
NZ (1) NZ569667A (enExample)
RU (1) RU2448106C2 (enExample)
SA (1) SA07280009B1 (enExample)
TW (2) TW201018678A (enExample)
UA (1) UA95267C2 (enExample)
UY (1) UY30112A1 (enExample)
WO (1) WO2007086800A1 (enExample)
ZA (1) ZA200806075B (enExample)

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EP2699157B1 (en) * 2011-04-21 2018-03-14 The Regents of The University of California Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles
US20140348748A1 (en) * 2011-09-16 2014-11-27 Lisheng Cai Beta-amyloid imaging agents, methods of manufacture, and methods of use thereof
CN102558091B (zh) * 2011-12-22 2014-10-08 合肥工业大学 一种苯并噻唑类衍生物及其用途
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EP3227287B1 (de) 2014-12-02 2019-08-07 Bayer Pharma Aktiengesellschaft Heteroaryl-substituierte imidazo[1,2-a]pyridine und ihre verwendung
BR112017019326B1 (pt) * 2015-03-12 2022-04-26 Fmc Corporation Composto, composição e método para controlar uma praga invertebrada
MX382156B (es) * 2015-08-28 2025-03-13 Chdi Foundation Inc Sondas para formar imagenes de proteina de huntingtina.
GB201617339D0 (en) 2016-10-12 2016-11-23 Lytix Biopharma As Therapeutic compounds
JP7168650B2 (ja) * 2017-08-02 2022-11-09 スピノジェニックス， インコーポレイテッド ベンゾチアゾールおよび関連化合物
TW201946624A (zh) 2018-05-09 2019-12-16 新旭生技股份有限公司 雜芳基化合物及其用途
US11844846B2 (en) 2018-05-16 2023-12-19 Emory University Styrylbenzothiazole derivatives and uses in imaging methods
SMT202500291T1 (it) * 2019-01-31 2025-09-12 Spinogenix Inc Forme solide di un promotore di spinogenesi
GB201914989D0 (en) * 2019-10-16 2019-11-27 Karin & Sten Mortstedt Cbd Solutions Ab Selective ligands for TAU Aggregates
CN114728071B (zh) 2019-11-13 2024-12-06 新旭生技股份有限公司 用于降解tau蛋白聚集体的化合物及其用途
KR102682408B1 (ko) * 2021-05-12 2024-07-05 에이치케이이노엔 주식회사 신규한 벤조티아졸 유도체, 이의 제조방법 및 이의 간질환 예방 또는 치료 용도
CN114478431B (zh) * 2022-03-09 2024-07-02 台州学院 一种双取代苯并噻吩类钾离子通道激动剂的制备方法
CN114380731B (zh) * 2022-03-09 2024-07-02 台州学院 一种kcnq钾离子通道激动剂、药物组合物及其应用
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Also Published As

Publication number Publication date
US20120207679A1 (en) 2012-08-16
US8163928B2 (en) 2012-04-24
NZ569667A (en) 2011-09-30
NO20083394L (no) 2008-10-02
AR059178A1 (es) 2008-03-12
ZA200806075B (en) 2012-12-27
TW200736252A (en) 2007-10-01
BRPI0707283A2 (pt) 2011-04-26
US8957215B2 (en) 2015-02-17
WO2007086800A1 (en) 2007-08-02
IL192876A0 (en) 2009-02-11
JP5289061B2 (ja) 2013-09-11
AU2007207904B2 (en) 2011-03-10
JP2009528271A (ja) 2009-08-06
CA2640213A1 (en) 2007-08-02
RU2448106C2 (ru) 2012-04-20
EP1981883A1 (en) 2008-10-22
TW201018678A (en) 2010-05-16
ECSP088645A (es) 2008-08-29
CN101410393A (zh) 2009-04-15
KR20080090542A (ko) 2008-10-08
EP1981883A4 (en) 2010-10-06
RU2008130965A (ru) 2010-03-10
AU2007207904A1 (en) 2007-08-02
AU2007207904C1 (en) 2011-10-13
CN101410393B (zh) 2012-01-25
US20090028787A1 (en) 2009-01-29
UY30112A1 (es) 2007-08-31
KR101406248B1 (ko) 2014-06-19
SA07280009B1 (ar) 2011-07-20

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