ATE533485T1 - Cetp-inhibitoren - Google Patents
Cetp-inhibitorenInfo
- Publication number
- ATE533485T1 ATE533485T1 AT06826999T AT06826999T ATE533485T1 AT E533485 T1 ATE533485 T1 AT E533485T1 AT 06826999 T AT06826999 T AT 06826999T AT 06826999 T AT06826999 T AT 06826999T AT E533485 T1 ATE533485 T1 AT E533485T1
- Authority
- AT
- Austria
- Prior art keywords
- cetp inhibitors
- cholesterol
- compounds
- treating
- useful
- Prior art date
Links
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 108010023302 HDL Cholesterol Proteins 0.000 abstract 1
- 238000008214 LDL Cholesterol Methods 0.000 abstract 1
- 108010028554 LDL Cholesterol Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73216805P | 2005-10-31 | 2005-10-31 | |
| PCT/US2006/042208 WO2007070173A2 (en) | 2005-10-31 | 2006-10-30 | Cetp inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE533485T1 true ATE533485T1 (de) | 2011-12-15 |
Family
ID=38163381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06826999T ATE533485T1 (de) | 2005-10-31 | 2006-10-30 | Cetp-inhibitoren |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8334290B2 (de) |
| EP (1) | EP1954287B2 (de) |
| JP (1) | JP5301999B2 (de) |
| AT (1) | ATE533485T1 (de) |
| AU (1) | AU2006325294B2 (de) |
| CA (1) | CA2627722A1 (de) |
| WO (1) | WO2007070173A2 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201018678A (en) | 2006-01-27 | 2010-05-16 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
| BRPI0710083A2 (pt) | 2006-03-31 | 2011-08-02 | Janssen Pharmaceutica Nv | entidade quìmica benzoimidazol-2-il pirimidina e pirazina, composição farmacêutica e uso destas |
| EP2004188B1 (de) | 2006-03-31 | 2010-09-01 | Janssen Pharmaceutica NV | Benzoimidazol-2-yl pyridine als modulatoren des histamin-h4-rezeptors |
| CA2656157A1 (en) * | 2006-06-23 | 2008-10-30 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| WO2008156717A1 (en) * | 2007-06-20 | 2008-12-24 | Merck & Co., Inc. | Cetp inhibitors derived from benzoxazole arylamides |
| CA2689525A1 (en) * | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | Cetp inhibitors derived from benzoxazole arylamides |
| EP2170058B1 (de) * | 2007-06-20 | 2013-07-03 | Merck Sharp & Dohme Corp. | Cetp-hemmer aus benzoxazolarylamiden |
| ATE539075T1 (de) * | 2007-08-02 | 2012-01-15 | Recordati Ireland Ltd | Neue heterocyclische verbindungen als mglu5- antagonisten |
| US8084466B2 (en) | 2007-12-18 | 2011-12-27 | Janssen Pharmaceutica Nv | Bicyclic heteroaryl-substituted imidazoles as modulators of the histamine H4 receptor |
| EP2300481B1 (de) | 2008-05-30 | 2015-09-30 | Merck Sharp & Dohme Corp. | Neue substituierte azabenzoxazole |
| US9371311B2 (en) | 2008-06-30 | 2016-06-21 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyrimidine derivatives |
| JP5739426B2 (ja) | 2010-07-09 | 2015-06-24 | 宇部興産株式会社 | 置換ピリジン化合物 |
| WO2012020725A1 (ja) * | 2010-08-10 | 2012-02-16 | 塩野義製薬株式会社 | Ｎｐｙ ｙ５受容体拮抗作用を有するヘテロ環誘導体 |
| CN103209695A (zh) | 2010-09-15 | 2013-07-17 | 弗·哈夫曼-拉罗切有限公司 | 氮杂苯并噻唑化合物、组合物及应用方法 |
| JPWO2013027694A1 (ja) * | 2011-08-24 | 2015-03-19 | 国立大学法人京都大学 | コンフォメーション病診断用分子イメージングプローブ |
| CN102977085B (zh) * | 2011-10-27 | 2015-07-29 | 四川大学 | 2-芳基-苯并[d]噁唑、2-芳基-苯并[d]噻唑衍生物及其制备方法和用途 |
| ES2599757T3 (es) | 2012-01-06 | 2017-02-03 | Daiichi Sankyo Company, Limited | Sales de aducto de ácido de un compuesto de piridina sustituido como inhibidores de la proteína de transferencia de ésteres de colesterilo (PTEC) |
| HUE047681T2 (hu) | 2013-03-06 | 2020-05-28 | Janssen Pharmaceutica Nv | A hisztamin H4 receptor benzimidazol-2-il-pirimidin modulátorai |
| EP3054945B1 (de) | 2013-10-10 | 2018-08-15 | Merck Sharp & Dohme Corp. | 3,3'-disubstituierte indoline als hemmer des cholesterinestertransferproteins |
| EP3083642B1 (de) | 2013-12-17 | 2018-09-05 | Merck Sharp & Dohme Corp. | Kondensierte bicyclische isoxazoline als hemmer des cholesterinestertransferproteins |
| WO2016018729A1 (en) | 2014-07-29 | 2016-02-04 | Merck Sharp & Dohme Corp. | Monocyclic isoxazolines as inhibitors of cholesterol ester transfer protein |
| US20170298081A1 (en) * | 2014-08-08 | 2017-10-19 | Kasuma Partners Inc. | Condensed heterocyclic compound |
| UY36390A (es) * | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
| MX2017005462A (es) | 2014-11-05 | 2017-07-28 | Flexus Biosciences Inc | Agentes inmunorreguladores. |
| WO2016089062A2 (en) * | 2014-12-02 | 2016-06-09 | C&C Research Laboratories | Heterocyclic derivatives and use thereof |
| KR20160066490A (ko) | 2014-12-02 | 2016-06-10 | 주식회사 씨앤드씨신약연구소 | 헤테로사이클 유도체 및 그의 용도 |
| MA41168A (fr) * | 2014-12-17 | 2017-10-24 | Acraf | Nouveaux composés antibactériens |
| GB201506658D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| GB201506660D0 (en) | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| TW201808914A (zh) * | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| WO2018008718A1 (ja) * | 2016-07-07 | 2018-01-11 | 保土谷化学工業株式会社 | ベンゾアゾール環構造を有する化合物および有機エレクトロルミネッセンス素子 |
| EP3558977B1 (de) | 2016-12-20 | 2020-10-28 | Bristol-Myers Squibb Company | Verfahren zur herstellung von tetrahydrocarbazolcarboxamidverbindungen |
| CN106928212B (zh) * | 2017-02-28 | 2020-03-17 | 牡丹江医学院 | 一种用于治疗阑尾炎的药物及其制备方法和应用 |
| KR102101234B1 (ko) * | 2017-04-18 | 2020-04-16 | 부산대학교 산학협력단 | 신규 sirt 1 활성화제 및 이의 의학적 용도 |
| WO2018205916A1 (zh) * | 2017-05-09 | 2018-11-15 | 南京圣和药业股份有限公司 | Fgfr4抑制剂及其制备与应用 |
| KR102009325B1 (ko) * | 2018-03-29 | 2019-08-09 | 한림대학교 산학협력단 | 노카벤즈옥사졸 유도체 합성방법 및 그 유도체를 포함하는 항염증 약학 조성물 |
| KR101997518B1 (ko) * | 2018-03-29 | 2019-10-01 | 한림대학교 산학협력단 | 노카벤즈옥사졸 g 및 노카벤즈옥사졸 유도체 합성방법 |
| KR101997516B1 (ko) * | 2018-03-29 | 2019-10-01 | 한림대학교 산학협력단 | 노카벤즈옥사졸 및 그 유도체 합성방법 |
| MX2021004134A (es) | 2018-10-10 | 2021-07-16 | Albert Einstein College Medicine | Benzoxazol y compuestos relacionados útiles como moduladores de autofagia mediada por chaperonas. |
| TR201904869A2 (tr) * | 2019-04-01 | 2020-10-21 | Anadolu Ueniversitesi | Anti-kanser etkili benzoksazol türevi bileşikler. |
| LT4232154T (lt) * | 2020-10-22 | 2025-02-10 | Evotec International Gmbh | Integruoto streso atsako kelio moduliatoriai |
| WO2022112205A1 (en) * | 2020-11-25 | 2022-06-02 | F. Hoffmann-La Roche Ag | Aromatic bridged ring amide derivatives for the treatment and prophylaxis of hepatitis b virus infection |
| CN116262744A (zh) * | 2021-12-13 | 2023-06-16 | 复旦大学 | 用于α-突触核蛋白聚集体成像的小分子探针 |
| CN120418231A (zh) * | 2022-12-30 | 2025-08-01 | 阿勒泰治疗公司 | 2-取代噻唑和苯并噻唑组合物和作为dux4抑制剂的方法 |
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| SE0202462D0 (sv) † | 2002-08-14 | 2002-08-14 | Astrazeneca Ab | Novel use |
| AU2003264407A1 (en) † | 2002-09-18 | 2004-04-08 | Mitsui Mining And Smelting Co., Ltd. | Electronic component burning jig |
| JP2006515274A (ja) | 2002-10-08 | 2006-05-25 | マサチューセッツ・インスティテュート・オブ・テクノロジー | コレステロール輸送の調節のための化合物 |
| WO2004046122A2 (en) | 2002-11-16 | 2004-06-03 | Oxford Glycosciences (Uk) Ltd | Benzoxazole, benzthiazole and benzimidazole acid derivatives and their use as heparanase inhibitors |
| CA2438032C (en) † | 2003-03-14 | 2013-05-07 | University Of Pittsburgh | Benzothiazole derivative compounds, compositions and uses |
| TW200505442A (en) * | 2003-05-19 | 2005-02-16 | Genomics Inst Of The Novartis Res Foundation | Immunosuppressant compounds and compositions |
| AU2003265967A1 (en) * | 2003-09-05 | 2005-04-21 | Georgia State University Research Foundation, Inc | Novel amidine compounds for treating microbial infections |
| WO2005030206A1 (en) † | 2003-09-24 | 2005-04-07 | Imclone Systems Incorporated | Aryl-1,3-azole derivatives and methods for inhibiting heparnase activity |
| US8067608B2 (en) * | 2003-09-29 | 2011-11-29 | The Johns Hopkins University | Hedgehog pathway antagonists |
| ES2323178T3 (es) * | 2003-09-30 | 2009-07-08 | Janssen Pharmaceutica Nv | Compuestos de benzoimidazol. |
| GB0326964D0 (en) * | 2003-11-19 | 2003-12-24 | Glaxo Group Ltd | Chemical compounds |
| JP4922924B2 (ja) * | 2004-04-13 | 2012-04-25 | メルク・シャープ・エンド・ドーム・コーポレイション | Ｃｅｔｐ阻害薬 |
| CN101087786A (zh) † | 2004-12-23 | 2007-12-12 | 霍夫曼-拉罗奇有限公司 | 杂环氨基甲酸酯衍生物，它们的制备及作为药剂的应用 |
| AU2006209117B2 (en) † | 2005-01-28 | 2009-12-10 | Daewoong Pharmaceutical Co., Ltd. | Novel benzoimidazole derivatives and pharmaceutical composition comprising the same |
| FR2884516B1 (fr) * | 2005-04-15 | 2007-06-22 | Cerep Sa | Antagonistes npy, preparation et utilisations |
| WO2007039170A1 (en) * | 2005-09-23 | 2007-04-12 | European Molecular Biology Laboratory (Embl) | Antagonists of topoisomerase activity and their use in inhibiting pathological conditions |
| AR055669A1 (es) † | 2005-10-03 | 2007-08-29 | Astrazeneca Ab | Derivados de 3h - imidazo[4, 5 -b]piridina como inhibidores selectivos de gsk3, metodos e internediarios para su preparacion, composiciones farmaceuticas que los contienen y su uso para la elaboracion de un medicamento para el tratamiento de enfermedades neurodegenerativas y mentales. |
| EP2004188B1 (de) † | 2006-03-31 | 2010-09-01 | Janssen Pharmaceutica NV | Benzoimidazol-2-yl pyridine als modulatoren des histamin-h4-rezeptors |
-
2006
- 2006-10-30 AT AT06826999T patent/ATE533485T1/de active
- 2006-10-30 WO PCT/US2006/042208 patent/WO2007070173A2/en not_active Ceased
- 2006-10-30 AU AU2006325294A patent/AU2006325294B2/en not_active Ceased
- 2006-10-30 CA CA002627722A patent/CA2627722A1/en not_active Abandoned
- 2006-10-30 EP EP06826999.2A patent/EP1954287B2/de not_active Not-in-force
- 2006-10-30 US US12/083,324 patent/US8334290B2/en active Active
- 2006-10-30 JP JP2008538054A patent/JP5301999B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8334290B2 (en) | 2012-12-18 |
| JP2009516649A (ja) | 2009-04-23 |
| AU2006325294B2 (en) | 2012-10-11 |
| WO2007070173A3 (en) | 2009-05-07 |
| CA2627722A1 (en) | 2007-06-21 |
| EP1954287A4 (de) | 2010-05-05 |
| EP1954287B2 (de) | 2016-02-24 |
| US20090264405A1 (en) | 2009-10-22 |
| EP1954287B1 (de) | 2011-11-16 |
| WO2007070173A2 (en) | 2007-06-21 |
| AU2006325294A1 (en) | 2007-06-21 |
| JP5301999B2 (ja) | 2013-09-25 |
| EP1954287A2 (de) | 2008-08-13 |
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