ATE310736T1 - Verbindungen zur bilddarstellung der alzheimer- krankenheit - Google Patents
Verbindungen zur bilddarstellung der alzheimer- krankenheitInfo
- Publication number
- ATE310736T1 ATE310736T1 AT02785662T AT02785662T ATE310736T1 AT E310736 T1 ATE310736 T1 AT E310736T1 AT 02785662 T AT02785662 T AT 02785662T AT 02785662 T AT02785662 T AT 02785662T AT E310736 T1 ATE310736 T1 AT E310736T1
- Authority
- AT
- Austria
- Prior art keywords
- disease
- compounds
- alzheimer
- imaging alzheimer
- imaging
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/0412—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K51/0419—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0130305.6A GB0130305D0 (en) | 2001-12-19 | 2001-12-19 | Compounds for imaging alzheimers disease |
PCT/GB2002/005641 WO2003051859A1 (en) | 2001-12-19 | 2002-12-12 | Compounds for imaging alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE310736T1 true ATE310736T1 (de) | 2005-12-15 |
Family
ID=9927890
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02785662T ATE310736T1 (de) | 2001-12-19 | 2002-12-12 | Verbindungen zur bilddarstellung der alzheimer- krankenheit |
Country Status (9)
Country | Link |
---|---|
US (1) | US7173061B2 (de) |
EP (1) | EP1463721B1 (de) |
JP (1) | JP4418237B2 (de) |
AT (1) | ATE310736T1 (de) |
AU (1) | AU2002350950A1 (de) |
DE (1) | DE60207612T2 (de) |
ES (1) | ES2254763T3 (de) |
GB (1) | GB0130305D0 (de) |
WO (1) | WO2003051859A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1631561B1 (de) | 2003-05-07 | 2010-08-18 | General Electric Company | Zusammensetzungen und verfahren zur in vivo abbildung von loeslichen beta-amyloid |
US7785566B2 (en) | 2003-11-06 | 2010-08-31 | Ge Healthcare, Inc. | Pharmaceutical compounds |
GB0416062D0 (en) * | 2004-07-19 | 2004-08-18 | Amersham Plc | Improved N4 chelator conjugates |
US7431914B2 (en) | 2003-11-24 | 2008-10-07 | Ge Healthcare As | Contrast agent |
ES2427963T3 (es) | 2004-07-02 | 2013-11-05 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Uso de derivados de tioflavina radiomarcados en formación de imágenes de amiloide para evaluación de las terapias antiamiloide |
ES2379987T3 (es) * | 2005-10-11 | 2012-05-07 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Compuestos de benzofurano marcados isotópicamente como radiotrazadores para proteínas amiloidógenas |
TW200736252A (en) | 2006-01-27 | 2007-10-01 | Astrazeneca Ab | Novel heteroaryl substituted benzothiazoles |
TW200813035A (en) | 2006-06-19 | 2008-03-16 | Astrazeneca Ab | Novel heteroaryl substituted benzoxazoles |
US7737183B2 (en) * | 2006-10-17 | 2010-06-15 | The Regents Of The University Of California | β-amyloid and neurofibrillary tangle imaging agents |
EP2081892A4 (de) * | 2006-11-17 | 2014-03-05 | Donald F Weaver | Verbindungen und verfahren zur behandlung von proteinfaltungserkrankungen |
RU2009125612A (ru) * | 2006-12-05 | 2011-01-20 | Нагасаки Юниверсити (Jp) | Композиция для диагностики, содержащая производные аурона |
JP2008231102A (ja) * | 2007-02-23 | 2008-10-02 | Hiroaki Okuno | アミロイドベータ凝集阻害作用を有するフェノール誘導体 |
TW200901998A (en) * | 2007-03-06 | 2009-01-16 | Astrazeneca Ab | Novel 2-heteroaryl substituted benzothiophenes and benzofuranes |
US8193363B2 (en) | 2008-08-29 | 2012-06-05 | Astrazeneca Ab | Compounds suitable as precursors to compounds that are useful for imaging amyloid deposits |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3947470A (en) | 1974-06-20 | 1976-03-30 | Smithkline Corporation | Substituted benzofurans and benzothiophenes |
US4024273A (en) | 1974-06-20 | 1977-05-17 | Smithkline Corporation | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity |
US5599951A (en) | 1989-09-15 | 1997-02-04 | Societe Civile Bioprojet | Amino acid derivatives, the process for their preparation and their applications to therapy |
AU1339795A (en) * | 1993-12-21 | 1995-07-10 | Eli Lilly And Company | Non-peptide tachykinin receptor antagonists |
-
2001
- 2001-12-19 GB GBGB0130305.6A patent/GB0130305D0/en not_active Ceased
-
2002
- 2002-12-12 JP JP2003552743A patent/JP4418237B2/ja not_active Expired - Fee Related
- 2002-12-12 AT AT02785662T patent/ATE310736T1/de not_active IP Right Cessation
- 2002-12-12 AU AU2002350950A patent/AU2002350950A1/en not_active Abandoned
- 2002-12-12 WO PCT/GB2002/005641 patent/WO2003051859A1/en active IP Right Grant
- 2002-12-12 EP EP02785662A patent/EP1463721B1/de not_active Expired - Lifetime
- 2002-12-12 ES ES02785662T patent/ES2254763T3/es not_active Expired - Lifetime
- 2002-12-12 US US10/499,069 patent/US7173061B2/en not_active Expired - Fee Related
- 2002-12-12 DE DE60207612T patent/DE60207612T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE60207612D1 (de) | 2005-12-29 |
AU2002350950A1 (en) | 2003-06-30 |
ES2254763T3 (es) | 2006-06-16 |
EP1463721B1 (de) | 2005-11-23 |
GB0130305D0 (en) | 2002-02-06 |
JP4418237B2 (ja) | 2010-02-17 |
US20050080130A1 (en) | 2005-04-14 |
WO2003051859A1 (en) | 2003-06-26 |
EP1463721A1 (de) | 2004-10-06 |
DE60207612T2 (de) | 2006-08-03 |
JP2005516935A (ja) | 2005-06-09 |
US7173061B2 (en) | 2007-02-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE310736T1 (de) | Verbindungen zur bilddarstellung der alzheimer- krankenheit | |
DE602004029580D1 (de) | Substituierte indolderivate für eine pharmazeutische zusammensetzung zur behandlung von atemwegserkrankungen | |
UA95267C2 (en) | Heteroaryl substituted benzothiazoles | |
EE200200716A (et) | Ühendid Alzheimeri tõve käitluseks | |
ATE343562T1 (de) | Verbindungen und verfahren zur behandlung der alzheimerschen krankheit | |
CY1112737T1 (el) | Ισοτοπικα σεσημασμενες ενωσεις βενζοfuran σαν παραγοντες απεικονισης για πρωτεϊνες δημιουργιας αμυλοειδους (αμυloid) | |
DK0907379T3 (da) | Bioaktiveret diagnostisk billeddannelseskontrastmiddel | |
CY1108514T1 (el) | Παραγωγα 1-φαινυλαλκανεκαρβοξυλικου οξεος για τη θεραπεια νευρογενων ασθενειων | |
HUP0100159A2 (hu) | Az Alzheimer-kór életben történő diagnosztizálására és amiloidlerakódás in vivo kimutatására és megelőzésére alkalmas vegyületek | |
DK2157192T3 (da) | Sammensætninger til diagnose og terapi af sygdomme forbundet med afvigende ekspression af futriner (R-spondiner) | |
EA200401114A3 (ru) | Замещённые гидроксиэтиламины | |
EE200300216A (et) | Radiofarmatseutilised ained Alzheimeri tõve diagnoosimiseks | |
ATE534736T1 (de) | Identifizierungsverfahren und verbindungen für die behandlung degenerativer und entzündlicher erkrankungen | |
DE602004016010D1 (de) | Verfahren zur ä11cü-radiomarkierung von phenthiazin und phenothiazinartige verbindungen | |
UA83691C2 (ru) | Применение замещенных 2-аминотетралинов для упреждающего лечения болезни паркинсона | |
ATE376428T1 (de) | Metallkomplexverbindungen | |
ZA200603178B (en) | Quick test for the diagnosis of Alzheimer's disease | |
BR0011728A (pt) | Método de inibir a agregação de proteìna amilóide e imagem de depósitos de amilóide | |
ATE522230T1 (de) | Biphenyle als bilderzeugungsmittel bei der alzheimerschen krankheit | |
IL172690A0 (en) | Methods for the diagnosis and prognosis of alzheimer's disease | |
AU2003236714A8 (en) | Diagnosis of alzheimer's disease based on the habeta42:habeta40 ratio | |
UY27570A1 (es) | Sal de ácido cítrico de un compuesto terapéutico y composiciones farmacéuticas que la contienen | |
EP1693671A4 (de) | Verfahren zur diagnose von morbus alzheimer | |
DE60334200D1 (de) | Verfahren zur messung von neprilysinaktivität | |
DE602007007362D1 (de) | Radioaktiv markierte verbindungen auf peptidbasis und ihre verwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |