UA80393C2 - Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці - Google Patents
Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці Download PDFInfo
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- UA80393C2 UA80393C2 UA2003076286A UA2003076286A UA80393C2 UA 80393 C2 UA80393 C2 UA 80393C2 UA 2003076286 A UA2003076286 A UA 2003076286A UA 2003076286 A UA2003076286 A UA 2003076286A UA 80393 C2 UA80393 C2 UA 80393C2
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- UA
- Ukraine
- Prior art keywords
- sodium
- acid
- composition according
- droplets
- excipients
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
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EP00126847 | 2000-12-07 | ||
PCT/EP2001/014307 WO2002045693A1 (en) | 2000-12-07 | 2001-12-06 | Pharmaceutical preparation comprising an active dispersed on a matrix |
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UA80393C2 true UA80393C2 (uk) | 2007-09-25 |
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UA2003076286A UA80393C2 (uk) | 2000-12-07 | 2001-06-12 | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
Country Status (28)
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US (2) | US7175854B2 (pt) |
EP (1) | EP1341527B1 (pt) |
JP (1) | JP4950409B2 (pt) |
KR (1) | KR20030072557A (pt) |
CN (2) | CN101810592A (pt) |
AT (1) | ATE519481T1 (pt) |
AU (2) | AU2002216073B2 (pt) |
BR (1) | BR0115987A (pt) |
CA (1) | CA2430828C (pt) |
CY (1) | CY1112333T1 (pt) |
CZ (1) | CZ20031881A3 (pt) |
DK (1) | DK1341527T3 (pt) |
EA (1) | EA007151B1 (pt) |
EE (1) | EE05256B1 (pt) |
ES (1) | ES2371060T3 (pt) |
HR (1) | HRP20030493B1 (pt) |
HU (1) | HUP0400566A3 (pt) |
IL (2) | IL155964A0 (pt) |
MX (1) | MXPA03005092A (pt) |
NO (1) | NO333722B1 (pt) |
NZ (1) | NZ526015A (pt) |
PL (1) | PL206595B1 (pt) |
PT (1) | PT1341527E (pt) |
SG (1) | SG148028A1 (pt) |
SI (1) | SI1341527T1 (pt) |
UA (1) | UA80393C2 (pt) |
WO (1) | WO2002045693A1 (pt) |
ZA (1) | ZA200305114B (pt) |
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FR2754177B1 (fr) * | 1996-10-07 | 1999-08-06 | Sanofi Sa | Microspheres pharmaceutiques d'acide valproique pour administration orale |
KR20030059318A (ko) * | 2000-12-07 | 2003-07-07 | 알타나 파마 아게 | 산 불안정성 활성 성분을 포함하는 현탁액 형태의 약학 제제 |
SI1341524T1 (sl) * | 2000-12-07 | 2012-02-29 | Nycomed Gmbh | Farmacevtski pripravek v obliki paste, ki obsega kislinsko labilno učinkovino |
UA80393C2 (uk) * | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
FR2818552B1 (fr) * | 2000-12-26 | 2003-02-07 | Servier Lab | Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine |
AU2002342917A1 (en) * | 2001-11-19 | 2003-06-10 | Altana Pharma Ag | Reversible proton pump inhibitors for the treatment of airway disorders |
FR2834894B1 (fr) * | 2002-01-21 | 2004-02-27 | Servier Lab | Composition pharmaceutique orodispersible de piribedil |
FR2834896B1 (fr) * | 2002-01-23 | 2004-02-27 | Servier Lab | Composition pharmaceutique orodispersible d'ivabradine |
FR2834890B1 (fr) * | 2002-01-23 | 2004-02-27 | Servier Lab | Composition pharmaceutique orodispersible d'agomelatine |
MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
ATE344026T1 (de) * | 2002-06-28 | 2006-11-15 | Speedel Pharma Ag | Pharmazeutische formulierung mit einem nichtpeptidischen renin-hemmer und surfactant |
JP5148813B2 (ja) * | 2002-07-03 | 2013-02-20 | タケダ ファーマシューティカルズ ユー.エス.エー. インコーポレイティド | プロトンポンプ阻害剤の液体剤形 |
US8877168B1 (en) | 2002-07-31 | 2014-11-04 | Senju Pharmaceuticals Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
EP1525884B1 (en) | 2002-07-31 | 2011-10-12 | Senju Pharmaceutical Co., Ltd. | Aqueous liquid preparations and light-stabilized aqueous liquid preparations |
US20080081834A1 (en) | 2002-07-31 | 2008-04-03 | Lippa Arnold S | Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders |
US20040127541A1 (en) * | 2002-07-31 | 2004-07-01 | Janet Codd | Bicifadine formulation |
CA2395931A1 (en) * | 2002-08-07 | 2004-02-07 | Bernard Charles Sherman | Solid compositions comprising gabapentin having improved stability |
KR20040016202A (ko) * | 2002-08-16 | 2004-02-21 | 주식회사 제이알팜 | 쓴맛이 차폐된 히드로코르티손 경구용 약제 조성물 및 그제조방법 |
AU2003276688A1 (en) * | 2002-09-02 | 2004-03-19 | Sun Pharmaceutical Industries Limited | Pharmaceutical composition of metaxalone with enhanced oral bioavailability |
UA80991C2 (en) | 2002-10-07 | 2007-11-26 | Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes | |
US7704527B2 (en) * | 2002-10-25 | 2010-04-27 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
US20060014801A1 (en) * | 2002-11-22 | 2006-01-19 | The Johns Hopkins University | Prevention and treatment of cognitive impairment using (R)-(-)-5-methyl-1-nicotynoyl-2-pyrazoline (MNP) and analogs |
CA2503290C (en) | 2003-03-10 | 2012-12-04 | Altana Pharma Ag | Novel process for the preparation of roflumilast |
TW200503783A (en) * | 2003-04-11 | 2005-02-01 | Altana Pharma Ag | Oral pharmaceutical preparation for proton pump antagonists |
TWI366442B (en) * | 2003-07-30 | 2012-06-21 | Novartis Ag | Palatable ductile chewable veterinary composition |
US7838029B1 (en) * | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
US7390503B1 (en) | 2003-08-22 | 2008-06-24 | Barr Laboratories, Inc. | Ondansetron orally disintegrating tablets |
CA2545584C (en) | 2003-11-17 | 2012-10-23 | Biomarin Pharmaceutical Inc. | Methods and compositions for the treatment of metabolic disorders |
EP1696881A2 (en) * | 2003-12-23 | 2006-09-06 | Sun Pharmaceutical Industries Limited | Stable oral composition |
KR100629771B1 (ko) * | 2004-01-27 | 2006-09-28 | 씨제이 주식회사 | 결정성이 감소되거나 무정형화된 올티프라즈의 제조방법 |
DE102004011512B4 (de) * | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmazeutische Zubereitung enthaltend Pimobendan |
PT1748756E (pt) | 2004-03-10 | 2009-07-20 | Bayer Schering Pharma Ag | Composições compreendendo drospirenona molecularmente dispersa |
KR100681660B1 (ko) * | 2004-03-17 | 2007-02-09 | 주식회사종근당 | 방출제어 펠릿의 약제학적 조성물 |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
US20110008327A1 (en) | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
US20100009928A1 (en) * | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
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PL2574341T3 (pl) | 2004-03-29 | 2017-09-29 | University Of South Florida | Efektywne leczenie guzów i raka fosforanem tricyrybiny |
US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
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