PT1748756E - Composições compreendendo drospirenona molecularmente dispersa - Google Patents
Composições compreendendo drospirenona molecularmente dispersa Download PDFInfo
- Publication number
- PT1748756E PT1748756E PT05708751T PT05708751T PT1748756E PT 1748756 E PT1748756 E PT 1748756E PT 05708751 T PT05708751 T PT 05708751T PT 05708751 T PT05708751 T PT 05708751T PT 1748756 E PT1748756 E PT 1748756E
- Authority
- PT
- Portugal
- Prior art keywords
- compositions
- molecularly dispersed
- drospirenone
- drospirenone molecularly
- gastro
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55135504P | 2004-03-10 | 2004-03-10 | |
EP04075713 | 2004-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1748756E true PT1748756E (pt) | 2009-07-20 |
Family
ID=34961545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT05708751T PT1748756E (pt) | 2004-03-10 | 2005-03-10 | Composições compreendendo drospirenona molecularmente dispersa |
Country Status (22)
Country | Link |
---|---|
EP (2) | EP1748756B1 (pt) |
JP (2) | JP2007528388A (pt) |
KR (1) | KR20060130723A (pt) |
AT (2) | ATE429900T1 (pt) |
AU (2) | AU2005221402B2 (pt) |
BR (1) | BRPI0508612A (pt) |
CA (1) | CA2558393A1 (pt) |
CR (1) | CR8631A (pt) |
CU (1) | CU20060173A7 (pt) |
CY (1) | CY1109265T1 (pt) |
DE (1) | DE602005014227D1 (pt) |
DK (1) | DK1748756T3 (pt) |
EA (1) | EA012570B1 (pt) |
EC (1) | ECSP066901A (pt) |
ES (1) | ES2325591T3 (pt) |
HR (1) | HRP20090381T1 (pt) |
IL (1) | IL177893A0 (pt) |
NZ (1) | NZ549792A (pt) |
PL (1) | PL1748756T3 (pt) |
PT (1) | PT1748756E (pt) |
SI (1) | SI1748756T1 (pt) |
WO (1) | WO2005087194A1 (pt) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY142989A (en) | 2004-03-10 | 2011-02-14 | Bayer Schering Pharma Ag | Stabilised supersaturated solids of lipophilic drugs |
US8475838B2 (en) | 2005-06-03 | 2013-07-02 | Sandoz Ag | Rapidly-dissolving pharmaceutical composition for inhibiting ovulation |
EP1767194A1 (de) * | 2005-06-09 | 2007-03-28 | Helm AG | Verfahren zur Herstellung von Adsorbaten des Drospirenons |
US20070104780A1 (en) * | 2005-10-25 | 2007-05-10 | Lipari John M | Formulation comprising a drug of low water solubility and method of use thereof |
WO2009138224A1 (en) * | 2008-05-14 | 2009-11-19 | Helm Ag | Pharmaceutical composition comprising drospirenone |
EP3210474B1 (en) * | 2008-09-17 | 2020-11-18 | Chiasma, Inc. | Pharmaceutical compositions comprising polypeptides and related methods of delivery |
US8512745B2 (en) | 2008-12-08 | 2013-08-20 | Laboratoire Hra Pharma | Ulipristal acetate tablets |
EP2398461A1 (en) * | 2009-02-18 | 2011-12-28 | Bayer Pharma Aktiengesellschaft | Formulation comprising drospirenone for subcutaneous or intramuscular administration |
ES2742525T3 (es) | 2009-10-01 | 2020-02-14 | Adare Pharmaceuticals Us L P | Composiciones de corticosteroides administradas oralmente |
AR081670A1 (es) | 2010-06-29 | 2012-10-10 | Leon Farma Sa Lab | Composicion farmaceutica que comprende drospirenona y kit anticonceptivo |
US11351122B1 (en) | 2010-07-28 | 2022-06-07 | Laboratorios Leon Farma Sa | Synthetic progestogens and pharmaceutical compositions comprising the same |
US10849857B2 (en) | 2010-07-28 | 2020-12-01 | Laboratorios Leon Farma Sa | Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same |
EP3459533A1 (en) | 2010-08-04 | 2019-03-27 | Grünenthal GmbH | Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for the treatment of nociceptive pain |
US9504664B2 (en) | 2010-10-29 | 2016-11-29 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US8895537B2 (en) | 2010-10-29 | 2014-11-25 | Infirst Healthcare Ltd. | Compositions and methods for treating cardiovascular diseases |
US10695431B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US11730709B2 (en) | 2010-10-29 | 2023-08-22 | Infirst Healthcare Limited | Compositions and methods for treating severe pain |
US10695432B2 (en) | 2010-10-29 | 2020-06-30 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US11224659B2 (en) | 2010-10-29 | 2022-01-18 | Infirst Healthcare Limited | Solid solution compositions and use in severe pain |
US9744132B2 (en) | 2010-10-29 | 2017-08-29 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US11202831B2 (en) | 2010-10-29 | 2021-12-21 | Infirst Healthcare Limited | Solid solution compositions and use in cardiovascular disease |
US9271950B2 (en) | 2010-10-29 | 2016-03-01 | Infirst Healthcare Limited | Compositions for treating chronic inflammation and inflammatory diseases |
US9308213B2 (en) | 2010-10-29 | 2016-04-12 | Infirst Healthcare Limited | Solid solution compositions and use in chronic inflammation |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
CA2856520C (en) | 2011-11-23 | 2021-04-06 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
CN103040725B (zh) * | 2012-12-26 | 2015-01-21 | 武汉九珑人福药业有限责任公司 | 一种利用研磨改善屈螺酮溶出的方法及屈螺酮固体分散体 |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
MY176771A (en) | 2013-06-25 | 2020-08-21 | Olam International Ltd | Processes for producing dark brown natural cocoa |
WO2015034678A2 (en) | 2013-09-06 | 2015-03-12 | Aptalis Pharmatech, Inc. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
MX2016014281A (es) | 2014-05-22 | 2017-02-22 | Therapeuticsmd Inc | Formulaciones y terapias de reemplazo de combinación de hormonas naturales. |
RU2016141135A (ru) | 2014-07-29 | 2018-08-28 | Терапьютиксмд, Инк. | Трансдермальный крем |
MA41462A (fr) | 2015-02-03 | 2021-05-12 | Chiasma Inc | Méthode de traitement de maladies |
US10596118B2 (en) * | 2015-03-10 | 2020-03-24 | Shionogi, Inc. | Solid dispersions |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
TWI728172B (zh) | 2016-08-18 | 2021-05-21 | 美商愛戴爾製藥股份有限公司 | 治療嗜伊紅性食道炎之方法 |
US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5770815A (en) * | 1980-10-21 | 1982-05-01 | Furointo Sangyo Kk | Absorption improver |
JPS5942313A (ja) * | 1982-09-01 | 1984-03-08 | Teijin Ltd | ポリビニルポリピロリドンを用いた製剤 |
JPH0723303B2 (ja) * | 1986-03-07 | 1995-03-15 | 株式会社資生堂 | 難溶性薬物含有マイクロエマルシヨン製剤 |
DE3702029A1 (de) * | 1987-01-24 | 1988-08-04 | Basf Ag | Waessriges oder pulverfoermiges, wasserdispergierbares praeparat eines in wasser schwerloeslichen pharmazeutischen wirkstoffs und verfahren zu seiner herstellung |
DE3916112A1 (de) * | 1989-05-16 | 1990-11-22 | Schering Ag | Dihydrospirorenon als antiandrogen |
DE4326240A1 (de) | 1993-08-02 | 1995-02-09 | Schering Ag | 15,15-Dialkyl-substituierte Derivate des Estradiols |
JPH11514979A (ja) * | 1995-09-07 | 1999-12-21 | フイズ テクノロジーズ リミテッド | 実質的に非溶解性の生体作用薬剤をバイオ・アベイラブルにするシステム |
US5789442A (en) | 1996-01-18 | 1998-08-04 | Schering Aktiengesellschaft | Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combination with estrogen or progesterone and/or other agents |
JP2002513750A (ja) * | 1998-05-07 | 2002-05-14 | エラン コーポレーシヨン ピーエルシー | 溶媒/助溶剤を含まないマイクロエマルジョン及びエマルジョンプレ濃縮物のドラッグデリバリーシステム |
ME00329B (me) * | 1999-08-31 | 2011-05-10 | Bayer Schering Pharma Ag | Farmaceutska kombinacija etiilestradiola i drospirenona za primjenu kao kontraceptiynog sredstva |
SI1611892T1 (sl) * | 2000-01-18 | 2010-01-29 | Bayer Schering Pharma Ag | Farmacevtski sestavki, ki obsegajo drospirenon |
UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
EP1260225A1 (en) | 2001-05-18 | 2002-11-27 | Pantarhei Bioscience B.V. | A pharmaceutical composition for use in hormone replacement therapy |
ATE452641T1 (de) | 2002-09-05 | 2010-01-15 | Pantarhei Bioscience Bv | Orale pharmazeutische zusammensetzung enthaltend 15-hydroxytestosteron und seine derivate |
DK1558265T3 (da) * | 2002-11-05 | 2010-03-15 | Bayer Schering Pharma Ag | Anvendelse af dropspirenon til behandling af hypertension |
-
2005
- 2005-03-10 PT PT05708751T patent/PT1748756E/pt unknown
- 2005-03-10 AT AT05708751T patent/ATE429900T1/de not_active IP Right Cessation
- 2005-03-10 PL PL05708751T patent/PL1748756T3/pl unknown
- 2005-03-10 ES ES05708751T patent/ES2325591T3/es active Active
- 2005-03-10 JP JP2007502436A patent/JP2007528388A/ja active Pending
- 2005-03-10 AT AT08011577T patent/ATE476961T1/de not_active IP Right Cessation
- 2005-03-10 NZ NZ549792A patent/NZ549792A/en unknown
- 2005-03-10 DK DK05708751T patent/DK1748756T3/da active
- 2005-03-10 BR BRPI0508612-4A patent/BRPI0508612A/pt not_active IP Right Cessation
- 2005-03-10 AU AU2005221402A patent/AU2005221402B2/en not_active Ceased
- 2005-03-10 EP EP05708751A patent/EP1748756B1/en not_active Revoked
- 2005-03-10 EA EA200601570A patent/EA012570B1/ru not_active IP Right Cessation
- 2005-03-10 CA CA002558393A patent/CA2558393A1/en not_active Abandoned
- 2005-03-10 DE DE602005014227T patent/DE602005014227D1/de not_active Revoked
- 2005-03-10 EP EP08011577A patent/EP1980242B1/en active Active
- 2005-03-10 KR KR1020067020960A patent/KR20060130723A/ko not_active Application Discontinuation
- 2005-03-10 SI SI200530738T patent/SI1748756T1/sl unknown
- 2005-03-10 WO PCT/IB2005/000665 patent/WO2005087194A1/en active Application Filing
-
2006
- 2006-09-05 IL IL177893A patent/IL177893A0/en unknown
- 2006-09-07 CU CU20060173A patent/CU20060173A7/es unknown
- 2006-09-14 CR CR8631A patent/CR8631A/es not_active Application Discontinuation
- 2006-10-02 EC EC2006006901A patent/ECSP066901A/es unknown
-
2009
- 2009-07-03 HR HR20090381T patent/HRP20090381T1/xx unknown
- 2009-07-28 CY CY20091100805T patent/CY1109265T1/el unknown
- 2009-11-25 AU AU2009240844A patent/AU2009240844A1/en not_active Abandoned
-
2010
- 2010-03-24 JP JP2010068645A patent/JP2010150289A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL177893A0 (en) | 2006-12-31 |
NZ549792A (en) | 2009-12-24 |
PL1748756T3 (pl) | 2009-10-30 |
EP1980242B1 (en) | 2010-08-11 |
EA200601570A1 (ru) | 2007-02-27 |
AU2005221402B2 (en) | 2009-12-17 |
ECSP066901A (es) | 2006-12-20 |
CY1109265T1 (el) | 2014-07-02 |
DK1748756T3 (da) | 2009-06-15 |
EP1980242A1 (en) | 2008-10-15 |
DE602005014227D1 (de) | 2009-06-10 |
CR8631A (es) | 2007-06-06 |
ATE429900T1 (de) | 2009-05-15 |
EP1748756B1 (en) | 2009-04-29 |
CA2558393A1 (en) | 2005-09-22 |
AU2009240844A1 (en) | 2009-12-17 |
EP1748756A1 (en) | 2007-02-07 |
SI1748756T1 (sl) | 2009-10-31 |
KR20060130723A (ko) | 2006-12-19 |
WO2005087194A1 (en) | 2005-09-22 |
ATE476961T1 (de) | 2010-08-15 |
AU2005221402A1 (en) | 2005-09-22 |
JP2010150289A (ja) | 2010-07-08 |
HRP20090381T1 (en) | 2009-09-30 |
ES2325591T3 (es) | 2009-09-09 |
EA012570B1 (ru) | 2009-10-30 |
CU20060173A7 (es) | 2009-09-08 |
JP2007528388A (ja) | 2007-10-11 |
BRPI0508612A (pt) | 2007-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL177893A0 (en) | Compositions comprising drospirenone molecularly dispersed | |
WO2006113505A3 (en) | Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same | |
WO2008021368A3 (en) | Compositions and methods for neuroprotection | |
WO2007149406A3 (en) | Modified coagulation factor ix polypeptides and use thereof for treatment | |
WO2006002365A3 (en) | Microparticles with high loadings of a bioactive agent | |
WO2007008752A3 (en) | Sustained release pharmaceutical compositions for highly water soluble drugs | |
IL184758A0 (en) | New pharmaceutical compositions useful in the transmucosal administration of drugs | |
HUP0500509A3 (en) | Micronized pharmaceutical or nutraceutical powder with immediate release | |
WO2004093795A3 (en) | Compositions for delivery of drug combinations | |
WO2008033351A3 (en) | Multimodal abuse resistant and extended release formulations | |
IL196426A (en) | Micro-particles based on amphiphilic copolymer, their preparation processes and their pharmaceutical preparations | |
DE60216305D1 (de) | Zusammensetzungen zur verabreichung von arzneimittelkombinationen | |
WO2007017331A3 (en) | Immediate release therapeutic systems for improved oral absorption of 7- [ (e) -tert-butyloxyiminomethyl] camptothecin | |
IL189270A (en) | Repamycins converted to phosphonate and their derivatives, pharmaceutical preparations containing them and their use in the prevention and treatment of bone and joint infections | |
PT1742927E (pt) | Derivados do ácido butanóico, processos para a sua preparação, composições farmacêuticas que os contêm, e suas aplicações terapêuticas | |
ZA200804207B (en) | Pharmaceutical composition comprising at least one anticancer drug and at least one polymer | |
HK1120417A1 (en) | Stable nanoparticle formulations | |
WO2009048940A3 (en) | Diacerein pharmaceutical formulations | |
WO2006128120A3 (en) | Novel lapachone compounds and methods of use thereof | |
TW200609000A (en) | Molecular dispersions of drospirenone | |
WO2004096125A3 (en) | Pharmaceutical compositions releasing their active agents from a buccal or sublingual location to overcome an absorption window problem | |
WO2007135293A3 (fr) | 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur préparation, compositions les contenant et utilisation | |
ZA200706710B (en) | 6-Phenylhex-5-enoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions them, and therapeutic uses thereof | |
WO2007135294A3 (fr) | 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur préparation, compositions les contenant et utilisation | |
TH93875B (th) | สารผสมตามสูตรที่ออกฤทธิ์ช้า ซึ่งประกอบด้วยออกทรีโอไทด์และพอลิแลคไทด์-โค-ไกลโคไลด์ พอลิเมอร์สองตัวหรือมากกว่า |