UA126389C2 - Антигензв'язувальний білок проти gitr і спосіб його застосування - Google Patents
Антигензв'язувальний білок проти gitr і спосіб його застосування Download PDFInfo
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- UA126389C2 UA126389C2 UAA201906793A UAA201906793A UA126389C2 UA 126389 C2 UA126389 C2 UA 126389C2 UA A201906793 A UAA201906793 A UA A201906793A UA A201906793 A UAA201906793 A UA A201906793A UA 126389 C2 UA126389 C2 UA 126389C2
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
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- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
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- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Engineering & Computer Science (AREA)
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- Communicable Diseases (AREA)
- Virology (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| US201662497428P | 2016-11-19 | 2016-11-19 | |
| US201762448644P | 2017-01-20 | 2017-01-20 | |
| PCT/US2017/062443 WO2018094300A1 (en) | 2016-11-19 | 2017-11-19 | Anti-gitr antigen-binding proteins and methods of use thereof |
Publications (1)
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| UA126389C2 true UA126389C2 (uk) | 2022-09-28 |
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| UAA201906793A UA126389C2 (uk) | 2016-11-19 | 2017-11-19 | Антигензв'язувальний білок проти gitr і спосіб його застосування |
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| EP (1) | EP3541845A1 (enExample) |
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| CO (1) | CO2019006424A2 (enExample) |
| IL (1) | IL266720A (enExample) |
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| UA (1) | UA126389C2 (enExample) |
| WO (1) | WO2018094300A1 (enExample) |
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| KR102239781B1 (ko) * | 2019-04-08 | 2021-04-13 | 주식회사 녹십자 | Gpnmb 및 cd3에 특이적으로 결합하는 이중특이적 항체 및 이의 용도 |
| US10994021B1 (en) * | 2020-04-11 | 2021-05-04 | Bliss Biopharmaceutical (Hangzhou) Co., Ltd. | Tetravalent antibody-drug conjugates and use thereof |
| CN116113401A (zh) | 2020-06-08 | 2023-05-12 | 华盛顿大学 | 抗体结合的纳米颗粒 |
| KR102475255B1 (ko) * | 2021-05-10 | 2022-12-09 | 메디맵바이오 주식회사 | 항-gitr 항체 및 이의 용도 |
| WO2023094507A1 (en) * | 2021-11-24 | 2023-06-01 | Formycon Ag | Improved ace2 fusion proteins |
| CN118946582A (zh) | 2022-03-15 | 2024-11-12 | 耶达研究及发展有限公司 | 抗糖皮质激素诱导的tnfr相关（gitr）蛋白抗体及其用途 |
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| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
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| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
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-
2017
- 2017-06-16 JO JOP/2019/0100A patent/JOP20190100A1/ar unknown
- 2017-11-19 JP JP2019527171A patent/JP7572147B2/ja active Active
- 2017-11-19 CN CN201780071351.3A patent/CN110248960A/zh active Pending
- 2017-11-19 KR KR1020197017116A patent/KR102574071B1/ko active Active
- 2017-11-19 BR BR112019010128A patent/BR112019010128A2/pt unknown
- 2017-11-19 WO PCT/US2017/062443 patent/WO2018094300A1/en not_active Ceased
- 2017-11-19 UA UAA201906793A patent/UA126389C2/uk unknown
- 2017-11-19 MA MA046844A patent/MA46844A/fr unknown
- 2017-11-19 EP EP17817953.7A patent/EP3541845A1/en active Pending
- 2017-11-19 MX MX2019005821A patent/MX2019005821A/es unknown
- 2017-11-19 AU AU2017362721A patent/AU2017362721A1/en not_active Abandoned
- 2017-11-20 TW TW106140182A patent/TWI783953B/zh not_active IP Right Cessation
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2018
- 2018-02-20 US US15/900,168 patent/US10988545B2/en active Active
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2019
- 2019-05-10 ZA ZA2019/02939A patent/ZA201902939B/en unknown
- 2019-05-17 PH PH12019501108A patent/PH12019501108A1/en unknown
- 2019-05-19 IL IL266720A patent/IL266720A/en unknown
- 2019-06-19 CO CONC2019/0006424A patent/CO2019006424A2/es unknown
-
2021
- 2021-03-10 US US17/197,547 patent/US20210269542A1/en not_active Abandoned
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| Publication number | Publication date |
|---|---|
| RU2019118800A3 (enExample) | 2021-03-23 |
| WO2018094300A1 (en) | 2018-05-24 |
| TW201819416A (zh) | 2018-06-01 |
| CN110248960A (zh) | 2019-09-17 |
| MA46844A (fr) | 2019-09-25 |
| US10988545B2 (en) | 2021-04-27 |
| US20210269542A1 (en) | 2021-09-02 |
| CO2019006424A2 (es) | 2019-08-20 |
| WO2018094300A8 (en) | 2019-05-02 |
| IL266720A (en) | 2019-07-31 |
| TWI783953B (zh) | 2022-11-21 |
| EP3541845A1 (en) | 2019-09-25 |
| BR112019010128A2 (pt) | 2019-10-08 |
| MX2019005821A (es) | 2019-10-07 |
| AU2017362721A1 (en) | 2019-05-23 |
| JP2019537449A (ja) | 2019-12-26 |
| JOP20190100A1 (ar) | 2019-05-01 |
| US20180208665A1 (en) | 2018-07-26 |
| ZA201902939B (en) | 2022-08-31 |
| JP7572147B2 (ja) | 2024-10-23 |
| KR20190095298A (ko) | 2019-08-14 |
| RU2019118800A (ru) | 2020-12-21 |
| KR102574071B1 (ko) | 2023-09-06 |
| PH12019501108A1 (en) | 2019-07-29 |
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