DK2316940T3 - Fokuserede biblioteker af genpakker - Google Patents
Fokuserede biblioteker af genpakkerInfo
- Publication number
- DK2316940T3 DK2316940T3 DK10182768.1T DK10182768T DK2316940T3 DK 2316940 T3 DK2316940 T3 DK 2316940T3 DK 10182768 T DK10182768 T DK 10182768T DK 2316940 T3 DK2316940 T3 DK 2316940T3
- Authority
- DK
- Denmark
- Prior art keywords
- display
- repackages
- libraries
- focused
- focused libraries
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Catalysts (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25638000P | 2000-12-18 | 2000-12-18 | |
EP01998098A EP1360288B1 (en) | 2000-12-18 | 2001-12-18 | Focused libraries of genetic packages |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2316940T3 true DK2316940T3 (da) | 2013-11-04 |
Family
ID=22972033
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10182768.1T DK2316940T3 (da) | 2000-12-18 | 2001-12-18 | Fokuserede biblioteker af genpakker |
DK01998098.6T DK1360288T3 (da) | 2000-12-18 | 2001-12-18 | Fokuserede biblioteker af genetiske pakker |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01998098.6T DK1360288T3 (da) | 2000-12-18 | 2001-12-18 | Fokuserede biblioteker af genetiske pakker |
Country Status (12)
Country | Link |
---|---|
US (10) | US20030119056A1 (da) |
EP (2) | EP1360288B1 (da) |
JP (2) | JP4860098B2 (da) |
AT (1) | ATE498718T1 (da) |
AU (1) | AU2002249854B2 (da) |
CA (2) | CA2784251A1 (da) |
DE (1) | DE60144063D1 (da) |
DK (2) | DK2316940T3 (da) |
ES (2) | ES2360479T3 (da) |
HK (1) | HK1156660A1 (da) |
PT (2) | PT2316940E (da) |
WO (1) | WO2002061071A2 (da) |
Families Citing this family (65)
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DK1276855T3 (da) * | 2000-04-17 | 2012-11-26 | Dyax Corp | Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie |
DE60144063D1 (de) | 2000-12-18 | 2011-03-31 | Dyax Corp | Gerichtete bibliotheken die genetisch verpackt sind |
US20040067532A1 (en) | 2002-08-12 | 2004-04-08 | Genetastix Corporation | High throughput generation and affinity maturation of humanized antibody |
GB0230203D0 (en) * | 2002-12-27 | 2003-02-05 | Domantis Ltd | Fc fusion |
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US7785903B2 (en) | 2004-04-09 | 2010-08-31 | Genentech, Inc. | Variable domain library and uses |
WO2006014498A2 (en) * | 2004-07-06 | 2006-02-09 | Bioren, Inc. | Universal antibody libraries |
CA2595906C (en) * | 2005-02-01 | 2014-04-22 | Dyax Corp. | Libraries and methods for isolating antibodies |
WO2007056441A2 (en) * | 2005-11-07 | 2007-05-18 | Genentech, Inc. | Binding polypeptides with diversified and consensus vh/vl hypervariable sequences |
US20070237764A1 (en) * | 2005-12-02 | 2007-10-11 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
EP1957540B1 (en) * | 2005-12-02 | 2012-06-13 | Genentech, Inc. | Binding polypeptides and uses thereof |
CN101370832B (zh) * | 2005-12-02 | 2014-07-02 | 健泰科生物技术公司 | 结合多肽及其用途 |
US8273688B2 (en) * | 2005-12-20 | 2012-09-25 | Morphosys Ag | Collection of HCDR3 regions and uses therefor |
US8148085B2 (en) | 2006-05-15 | 2012-04-03 | Sea Lane Biotechnologies, Llc | Donor specific antibody libraries |
CA2652452C (en) * | 2006-05-15 | 2018-07-31 | Sea Lane Biotechnologies, Llc | Neutralizing antibodies to influenza viruses |
EP3753947A1 (en) * | 2007-09-14 | 2020-12-23 | Adimab, LLC | Rationally designed, synthetic antibody libraries and uses therefor |
US8877688B2 (en) | 2007-09-14 | 2014-11-04 | Adimab, Llc | Rationally designed, synthetic antibody libraries and uses therefor |
WO2009114815A1 (en) * | 2008-03-13 | 2009-09-17 | Dyax Corp | Libraries of genetic packages comprising novel hc cdr3 designs |
CA2968164C (en) | 2008-04-24 | 2019-08-20 | Dyax Corp. | Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs |
JP2013504602A (ja) * | 2009-09-14 | 2013-02-07 | ダイアックス コーポレーション | 新しく設計したhccdr3を含む遺伝子パッケージライブラリー |
CN103282560B (zh) | 2010-07-16 | 2016-08-03 | 阿迪马布有限责任公司 | 抗体文库 |
DK2640742T3 (da) | 2010-11-19 | 2018-12-03 | Morphosys Ag | Samling af antistofsekvenser og disses anvendelser |
EP2744931B1 (en) * | 2011-08-18 | 2018-05-02 | Affinity Biosciences Pty Ltd | Soluble polypeptides |
SI2859017T1 (sl) | 2012-06-08 | 2019-05-31 | Sutro Biopharma, Inc. | Protitelesa, ki vsebujejo specifične nenaravne aminokislinske ostanke, postopki njihove priprave in postopki njihove uporabe |
ES2865473T3 (es) | 2013-07-10 | 2021-10-15 | Sutro Biopharma Inc | Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso |
CN106413439B (zh) | 2014-02-10 | 2019-10-18 | 菲利普莫里斯生产公司 | 用于气溶胶生成系统的加热器组件 |
DK3126384T3 (da) | 2014-04-01 | 2021-01-18 | Adimab Llc | Multispecifikke antistofanaloger omfattende en fælles letkæde, og fremgangsmåder til deres fremstilling og anvendelse |
TWI695011B (zh) | 2014-06-18 | 2020-06-01 | 美商梅爾莎納醫療公司 | 抗her2表位之單株抗體及其使用之方法 |
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EP3821730B1 (en) | 2015-07-09 | 2023-06-14 | Philip Morris Products S.A. | Heater assembly for an aerosol-generating system |
US20190330336A1 (en) | 2015-11-19 | 2019-10-31 | Sutro Biopharma, Inc. | Anti-lag3 antibodies, compositions comprising anti-lag3 antibodies and methods of making and using anti-lag3 antibodies |
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US10947317B2 (en) | 2016-03-15 | 2021-03-16 | Mersana Therapeutics, Inc. | NaPi2b-targeted antibody-drug conjugates and methods of use thereof |
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EP3652209A2 (en) | 2017-07-11 | 2020-05-20 | Compass Therapeutics LLC | Agonist antibodies that bind human cd137 and uses thereof |
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US11718679B2 (en) | 2017-10-31 | 2023-08-08 | Compass Therapeutics Llc | CD137 antibodies and PD-1 antagonists and uses thereof |
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US11993658B2 (en) | 2018-03-26 | 2024-05-28 | Sutro Biopharma, Inc. | Anti-BCMA antibodies and treatment methods |
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2001
- 2001-12-18 DE DE60144063T patent/DE60144063D1/de not_active Expired - Lifetime
- 2001-12-18 ES ES01998098T patent/ES2360479T3/es not_active Expired - Lifetime
- 2001-12-18 CA CA2784251A patent/CA2784251A1/en not_active Abandoned
- 2001-12-18 AT AT01998098T patent/ATE498718T1/de active
- 2001-12-18 WO PCT/US2001/050297 patent/WO2002061071A2/en active Application Filing
- 2001-12-18 DK DK10182768.1T patent/DK2316940T3/da active
- 2001-12-18 DK DK01998098.6T patent/DK1360288T3/da active
- 2001-12-18 EP EP01998098A patent/EP1360288B1/en not_active Expired - Lifetime
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- 2001-12-18 EP EP10182768.1A patent/EP2316940B1/en not_active Expired - Lifetime
- 2001-12-18 PT PT101827681T patent/PT2316940E/pt unknown
- 2001-12-18 JP JP2002561628A patent/JP4860098B2/ja not_active Expired - Lifetime
- 2001-12-18 PT PT01998098T patent/PT1360288E/pt unknown
- 2001-12-18 US US10/026,925 patent/US20030119056A1/en not_active Abandoned
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2006
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