DK1276855T3 - Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie - Google Patents

Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie

Info

Publication number
DK1276855T3
DK1276855T3 DK01927108.9T DK01927108T DK1276855T3 DK 1276855 T3 DK1276855 T3 DK 1276855T3 DK 01927108 T DK01927108 T DK 01927108T DK 1276855 T3 DK1276855 T3 DK 1276855T3
Authority
DK
Denmark
Prior art keywords
members
display libraries
genetic packages
peptide family
constructing display
Prior art date
Application number
DK01927108.9T
Other languages
English (en)
Inventor
Robert C Ladner
Edward Hirsch Cohen
Horacio Gabriel Nastri
Rene Hoet
Kristin L Rookey
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Application granted granted Critical
Publication of DK1276855T3 publication Critical patent/DK1276855T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
DK01927108.9T 2000-04-17 2001-04-17 Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie DK1276855T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19806900P 2000-04-17 2000-04-17
PCT/US2001/012454 WO2001079481A2 (en) 2000-04-17 2001-04-17 Methods of constructing display libraries of genetic packages for members of a diverse family of peptides

Publications (1)

Publication Number Publication Date
DK1276855T3 true DK1276855T3 (da) 2012-11-26

Family

ID=22731873

Family Applications (3)

Application Number Title Priority Date Filing Date
DK10156326.0T DK2199393T3 (da) 2000-04-17 2001-04-17 Hidtil ukendte fremgangsmåder til opbygning af biblioteker over genetiske pakker, der kollektivt viser medlemmerne af en forskelligartet familie af peptider, polypeptider eller proteiner
DK10179786T DK2308982T3 (da) 2000-04-17 2001-04-17 Fremgangsmåder til konstruering af præsentationsbiblioteker af genetiske pakker til medlemmer af en uensartet familie af peptider
DK01927108.9T DK1276855T3 (da) 2000-04-17 2001-04-17 Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK10156326.0T DK2199393T3 (da) 2000-04-17 2001-04-17 Hidtil ukendte fremgangsmåder til opbygning af biblioteker over genetiske pakker, der kollektivt viser medlemmerne af en forskelligartet familie af peptider, polypeptider eller proteiner
DK10179786T DK2308982T3 (da) 2000-04-17 2001-04-17 Fremgangsmåder til konstruering af præsentationsbiblioteker af genetiske pakker til medlemmer af en uensartet familie af peptider

Country Status (10)

Country Link
US (2) US20040029113A1 (da)
EP (4) EP2199393B1 (da)
JP (3) JP5149476B2 (da)
AU (3) AU2001253589B2 (da)
CA (2) CA2798625C (da)
DK (3) DK2199393T3 (da)
ES (3) ES2531551T3 (da)
HK (2) HK1145515A1 (da)
PT (1) PT2308982E (da)
WO (1) WO2001079481A2 (da)

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US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
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US9873957B2 (en) 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
WO2009132287A2 (en) 2008-04-24 2009-10-29 Dyax Corp. Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
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Also Published As

Publication number Publication date
HK1145515A1 (en) 2011-04-21
US9382535B2 (en) 2016-07-05
EP1276855A2 (en) 2003-01-22
AU5358901A (en) 2001-10-30
JP2014064586A (ja) 2014-04-17
JP5599745B2 (ja) 2014-10-01
DK2308982T3 (da) 2015-03-02
WO2001079481A8 (en) 2002-12-19
ES2531551T3 (es) 2015-03-17
EP2199393A1 (en) 2010-06-23
CA2406236C (en) 2013-02-19
ES2400302T3 (es) 2013-04-09
EP2308982A1 (en) 2011-04-13
AU2007211861B2 (en) 2009-06-11
US20060166252A1 (en) 2006-07-27
ES2400302T8 (es) 2013-04-25
EP2295580A1 (en) 2011-03-16
JP5149476B2 (ja) 2013-02-20
AU2007211861A1 (en) 2007-09-06
EP1276855B1 (en) 2012-10-24
CA2798625C (en) 2017-01-24
WO2001079481A2 (en) 2001-10-25
JP2011135893A (ja) 2011-07-14
DK2199393T3 (da) 2012-11-26
EP2308982B1 (en) 2014-11-26
EP2199393B1 (en) 2012-10-31
ES2393535T3 (es) 2012-12-26
CA2798625A1 (en) 2001-10-25
JP5956413B2 (ja) 2016-07-27
HK1156656A1 (en) 2012-06-15
JP2003530853A (ja) 2003-10-21
PT2308982E (pt) 2015-03-04
WO2001079481A3 (en) 2002-07-04
US20040029113A1 (en) 2004-02-12
AU2001253589B2 (en) 2007-08-16
CA2406236A1 (en) 2001-10-25

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