TWI711630B - 抗cd73抗體及其用途 - Google Patents
抗cd73抗體及其用途 Download PDFInfo
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- TWI711630B TWI711630B TW104138281A TW104138281A TWI711630B TW I711630 B TWI711630 B TW I711630B TW 104138281 A TW104138281 A TW 104138281A TW 104138281 A TW104138281 A TW 104138281A TW I711630 B TWI711630 B TW I711630B
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- G01N2333/914—Hydrolases (3)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462083056P | 2014-11-21 | 2014-11-21 | |
| US62/083,056 | 2014-11-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW201625693A TW201625693A (zh) | 2016-07-16 |
| TWI711630B true TWI711630B (zh) | 2020-12-01 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW104138281A TWI711630B (zh) | 2014-11-21 | 2015-11-19 | 抗cd73抗體及其用途 |
| TW109137987A TWI758928B (zh) | 2014-11-21 | 2015-11-19 | 抗cd73抗體及其用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW109137987A TWI758928B (zh) | 2014-11-21 | 2015-11-19 | 抗cd73抗體及其用途 |
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Families Citing this family (156)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3153526B1 (en) | 2008-01-31 | 2020-09-23 | INSERM - Institut National de la Santé et de la Recherche Médicale | Antibodies against human cd39 and use thereof for inhibiting t regulatory cells activity |
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| KR101791430B1 (ko) | 2009-11-30 | 2017-10-30 | 얀센 바이오테크 인코포레이티드 | 이펙터 기능이 제거된 항체 Fc 돌연변이체 |
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| Rust, Steven, et al. "Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’breast cancer cell type." Molecular cancer 12.1 (2013): 11. |
| Rust, Steven, et al. "Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’breast cancer cell type." Molecular cancer 12.1 (2013): 11. Terp, Mikkel G., et al. "Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells." The Journal of Immunology 191.8 (2013): 4165-4173. * |
| Terp, Mikkel G., et al. "Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells." The Journal of Immunology 191.8 (2013): 4165-4173. |
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