TNSN89026A1 - Methode de detection de sequences de nucleotides - Google Patents

Methode de detection de sequences de nucleotides

Info

Publication number
TNSN89026A1
TNSN89026A1 TNTNSN89026A TNSN89026A TNSN89026A1 TN SN89026 A1 TNSN89026 A1 TN SN89026A1 TN TNSN89026 A TNTNSN89026 A TN TNSN89026A TN SN89026 A TNSN89026 A TN SN89026A TN SN89026 A1 TNSN89026 A1 TN SN89026A1
Authority
TN
Tunisia
Prior art keywords
nucleotide sequences
detecting nucleotide
detecting
kits
production
Prior art date
Application number
TNTNSN89026A
Other languages
English (en)
French (fr)
Inventor
Clive Robert Newton
Alexander Fred Markham
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26293607&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TNSN89026(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB888805692A external-priority patent/GB8805692D0/en
Priority claimed from GB888814170A external-priority patent/GB8814170D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of TNSN89026A1 publication Critical patent/TNSN89026A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nonwoven Fabrics (AREA)
  • Communication Cables (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
TNTNSN89026A 1988-03-10 1989-03-09 Methode de detection de sequences de nucleotides TNSN89026A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888805692A GB8805692D0 (en) 1988-03-10 1988-03-10 Method of detecting nucleotide sequences
GB888814170A GB8814170D0 (en) 1988-06-15 1988-06-15 Method of detecting nucleotide sequences

Publications (1)

Publication Number Publication Date
TNSN89026A1 true TNSN89026A1 (fr) 1991-02-04

Family

ID=26293607

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN89026A TNSN89026A1 (fr) 1988-03-10 1989-03-09 Methode de detection de sequences de nucleotides

Country Status (26)

Country Link
US (1) US5595890A (enExample)
EP (1) EP0332435B2 (enExample)
JP (1) JP2853864B2 (enExample)
KR (1) KR970003151B1 (enExample)
CN (1) CN1034673C (enExample)
AT (1) ATE75262T1 (enExample)
AU (1) AU614584B2 (enExample)
BG (1) BG87585A (enExample)
BR (1) BR8901136A (enExample)
CA (1) CA1323592C (enExample)
DE (1) DE68901285D1 (enExample)
DK (1) DK175527B1 (enExample)
ES (1) ES2039294T5 (enExample)
FI (1) FI891126A7 (enExample)
GR (2) GR3004442T3 (enExample)
HU (1) HUT52565A (enExample)
IE (1) IE61148B1 (enExample)
IL (1) IL89545A (enExample)
MY (1) MY104957A (enExample)
NO (1) NO174825B (enExample)
NZ (1) NZ228266A (enExample)
PL (1) PL162338B1 (enExample)
PT (1) PT89980B (enExample)
TN (1) TNSN89026A1 (enExample)
YU (1) YU49789A (enExample)
ZW (1) ZW3388A1 (enExample)

Families Citing this family (271)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4038804A1 (de) * 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Verfahren zur genus- oder/und spezies-spezifischen detektion von bakterien in einer probenfluessigkeit
EP0333465B1 (en) * 1988-03-18 1994-07-13 Baylor College Of Medicine Mutation detection by competitive oligonucleotide priming
FR2650840B1 (fr) * 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
GB8920097D0 (en) * 1989-09-06 1989-10-18 Ici Plc Amplification processes
JPH03123500A (ja) * 1989-10-06 1991-05-27 Canon Inc 核酸の分別方法
GB9001181D0 (en) * 1990-01-18 1990-03-21 Imp Cancer Res Tech Genetic assay
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
GB9006924D0 (en) * 1990-03-28 1990-05-23 Imperial College Prognosis of hepatitis infection
DE69126064T2 (de) * 1990-06-22 1997-08-28 Hoffmann La Roche Nachweis von schwachen Metabolisierungsreagentien von Drogen
US5844108A (en) * 1990-06-22 1998-12-01 Roche Molecular Systems, Inc. Primers targeted to NAT2 gene for detection of poor metabolizers of drugs
GB9019512D0 (en) * 1990-09-06 1990-10-24 Ici Plc Assay method
FR2668162B1 (fr) * 1990-10-17 1993-01-22 Eurobio Lab Fragments d'adn, procede et coffret de diagnostic pour la detection des porteurs de la mutation delta-f-508 responsable de la mucoviscidose.
IE66125B1 (en) * 1991-01-31 1995-12-13 Zeneca Ltd Detection method for variant nucleotides
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
US5853989A (en) * 1991-08-27 1998-12-29 Zeneca Limited Method of characterisation of genomic DNA
EP0731177B1 (en) * 1991-08-27 2000-03-01 Zeneca Limited Method of characterising genomic DNA
DE4129653A1 (de) * 1991-09-06 1993-03-11 Boehringer Mannheim Gmbh Verfahren zum nachweis aehnlicher nukleinsaeuren
IL103935A0 (en) * 1991-12-04 1993-05-13 Du Pont Method for the identification of microorganisms by the utilization of directed and arbitrary dna amplification
US5541060A (en) * 1992-04-22 1996-07-30 Arch Development Corporation Detection of glucokinase-linked early-onset non-insulin-dependent diabetes mellitus
US6207368B1 (en) 1992-08-04 2001-03-27 Beckman Coulter, Inc. Methods and reagents for controlling chain extension and ligation chain reactions
US6180338B1 (en) 1992-08-04 2001-01-30 Beckman Coulter, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences
AU4848393A (en) * 1992-09-25 1994-04-26 Abbott Laboratories Ligase chain reaction method for detecting small mutations
EP0710296A4 (en) * 1993-07-23 1999-05-26 Bio Rad Laboratories LINEAR AMPLIFICATION OF NUCLEIC ACIDS
US6335184B1 (en) 1993-07-23 2002-01-01 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
AU1911395A (en) * 1994-02-04 1995-08-21 Beckman Instruments, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences
MX9701075A (es) 1994-08-12 1998-03-31 Myriad Genetics Inc Mutaciones en vivo y polimorfismos en el gen de susceptibilidad al cancer de pecho y ovario enlazado con 17q.
WO1996005308A1 (en) 1994-08-12 1996-02-22 Myriad Genetics, Inc. Method for diagnosing a predisposition for breast and ovarian cancer
FR2737732B1 (fr) * 1995-08-07 1997-10-10 Ass Francaise Contre La Myopat Test co-dominant de diagnostic genetique
NZ326525A (en) 1995-12-18 1999-11-29 Endorecherche Inc Chromosome 13-linked breast cancer susceptibility gene
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
EP0870041B1 (en) 1995-12-22 2007-01-24 The University of Utah Research Foundation KVLQT1 - A LONG QT SYNDROME GENE WHICH ENCODES KVLQT1 WHICH COASSEMBLES WITH minK TO FORM CARDIAC Iks POTASSIUM CHANNELS
NO960163D0 (no) * 1996-01-15 1996-01-15 Thomas Berg Mutasjonsdeteksjon av bovin
US5612473A (en) * 1996-01-16 1997-03-18 Gull Laboratories Methods, kits and solutions for preparing sample material for nucleic acid amplification
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
GB9609441D0 (en) * 1996-05-04 1996-07-10 Zeneca Ltd Process
US6361940B1 (en) 1996-09-24 2002-03-26 Qiagen Genomics, Inc. Compositions and methods for enhancing hybridization and priming specificity
IL119342A0 (en) * 1996-10-02 1997-01-10 Yeda Research And Development C Methods for priming and DNA sequencing
US6566101B1 (en) 1997-06-16 2003-05-20 Anthony P. Shuber Primer extension methods for detecting nucleic acids
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
GB9721240D0 (en) * 1997-10-08 1997-12-03 Zeneca Ltd Assay
US6794133B1 (en) 1997-12-11 2004-09-21 The General Hospital Corporation Broad range PCR amplification techniques
WO1999044045A1 (en) * 1998-02-27 1999-09-02 Massachusetts Institute Of Technology Single molecule detection with surface-enhanced raman scattering and applications in dna or rna sequencing
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6207379B1 (en) 1998-09-11 2001-03-27 One Lambda Method for amplification of DNA
JP2002531130A (ja) 1998-12-08 2002-09-24 チルドレンズ ホスピタル アンド レジオナル メディカル センター ＥｓｃｈｅｒｉｃｈｉａｃｏｌｉＯ１５７：Ｈ７と他の株とを識別する多形遺伝子座
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US6503718B2 (en) 1999-01-10 2003-01-07 Exact Sciences Corporation Methods for detecting mutations using primer extension for detecting disease
WO2000056916A2 (en) 1999-03-18 2000-09-28 Exiqon A/S Detection of mutations in genes by specific lna primers
US20030215821A1 (en) * 1999-04-20 2003-11-20 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
US20020025519A1 (en) * 1999-06-17 2002-02-28 David J. Wright Methods and oligonucleotides for detecting nucleic acid sequence variations
US20030165913A1 (en) * 1999-06-17 2003-09-04 Sha-Sha Wang Methods for detecting nucleic acid sequence variations
EP1061134A3 (en) * 1999-06-17 2003-01-08 Becton Dickinson and Company Oligonucleotides for amplification and detection of hemochromatosis genes
JP2003510017A (ja) 1999-06-22 2003-03-18 インビトロジェン コーポレイション 核酸の検出および識別のために改良されたプライマーおよび方法
US6830902B1 (en) 1999-07-02 2004-12-14 Invitrogen Corporation Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
EP1072679A3 (en) * 1999-07-20 2002-07-31 Agilent Technologies, Inc. (a Delaware corporation) Method of producing nucleic acid molecules with reduced secondary structure
DE10038229B4 (de) 1999-08-24 2011-06-09 LG Electronics Inc., Kangnam-gu Verfahren und Vorrichtung zur Ratenanpassung in einem Mobilkommunikationssystem
US6528066B1 (en) 1999-09-14 2003-03-04 University Of Iowa Research Foundation Variant varicella-zoster viruses and methods of use
WO2001023410A2 (en) * 1999-09-28 2001-04-05 Genaissance Pharmaceuticals, Inc. Drug target isogenes: polymorphisms in the interleukin 13 gene
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
US20030148301A1 (en) * 1999-12-10 2003-08-07 Toshiya Aono Method of detecting nucleotide polymorphism
AU2001236491A1 (en) * 2000-01-18 2003-09-16 Quantom Dot Corporation Oligonucleotide-tagged semiconductor nanocrystals for microarray and fluorescence in situ hybridization
US20050214825A1 (en) * 2000-02-07 2005-09-29 John Stuelpnagel Multiplex sample analysis on universal arrays
US8076063B2 (en) * 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) * 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US7582420B2 (en) * 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US7435541B2 (en) * 2000-05-23 2008-10-14 Sequenom, Inc. Restriction enzyme genotyping
US7659054B1 (en) * 2000-05-23 2010-02-09 Nuvelo, Inc. Methods for genetic analysis of DNA to detect sequence variances
AU2000257122A1 (en) * 2000-07-12 2002-01-21 Bionex, Inc. Method for detecting sequence variation of nucleic acid
JP3638516B2 (ja) * 2000-09-28 2005-04-13 株式会社日立製作所 核酸検出方法および核酸検出キット
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
US6986992B2 (en) * 2001-03-30 2006-01-17 Amersham Biosciences Ab P450 single nucleotide polymorphism biochip analysis
CN1186456C (zh) * 2001-04-30 2005-01-26 曹卫 通用模板核酸检测方法和试剂盒
US7888324B2 (en) 2001-08-01 2011-02-15 Genzyme Corporation Antisense modulation of apolipoprotein B expression
US7407943B2 (en) 2001-08-01 2008-08-05 Isis Pharmaceuticals, Inc. Antisense modulation of apolipoprotein B expression
BR0212773A (pt) 2001-09-24 2004-10-13 One Lambda Métodos para detecção de sequências-alvo de ácido nucléico com marcadores diagnósticos
US20030165859A1 (en) * 2001-10-23 2003-09-04 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
WO2003066897A2 (en) * 2002-02-08 2003-08-14 Evotec Technologies Gmbh Specific multiplex analysis of nucleic acids
AU2003213107A1 (en) 2002-02-15 2003-09-09 Exact Sciences Corporation Methods for analysis of molecular events
JP3752466B2 (ja) * 2002-04-24 2006-03-08 株式会社日立製作所 遺伝子検査方法
WO2004013346A2 (en) 2002-08-02 2004-02-12 Orchid Biosciences, Inc. Methods and compositions for genotyping
US7192700B2 (en) 2002-12-20 2007-03-20 Orchid Cellmark Inc. Methods and compositions for conducting primer extension and polymorphism detection reactions
AU2003236461B2 (en) 2002-08-29 2009-05-28 Epigenomics Ag Improved method for bisulfite treatment
US20040121374A1 (en) * 2002-10-02 2004-06-24 Yoshihide Iwaki Method for detecting single nucleotide polymorphisms
US20040259105A1 (en) * 2002-10-03 2004-12-23 Jian-Bing Fan Multiplex nucleic acid analysis using archived or fixed samples
ATE399882T1 (de) * 2002-11-07 2008-07-15 Yoichi Matsubara Verfahren zum genmutationsnachweis
US7511131B2 (en) 2002-11-13 2009-03-31 Genzyme Corporation Antisense modulation of apolipoprotein B expression
CA2507189C (en) 2002-11-27 2018-06-12 Sequenom, Inc. Fragmentation-based methods and systems for sequence variation detection and discovery
ATE373673T1 (de) * 2003-01-29 2007-10-15 Hoffmann La Roche Verbessertes verfahren zur behandlung durch bisulfit
WO2004081224A2 (en) * 2003-03-11 2004-09-23 Gene Check, Inc. Reca-assisted allele specific oligonucleotide extension method
WO2004092412A2 (en) 2003-03-31 2004-10-28 Roche Diagnostics Gmbh Compositions and methods for detecting certain flaviviruses, including members of the japanese encephalitis virus serogroup
US20040219532A1 (en) * 2003-04-30 2004-11-04 Sampson Jeffrey R. Internal references measurements
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20040259100A1 (en) * 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
AU2004253882B2 (en) * 2003-06-20 2010-06-10 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
GB0317592D0 (en) 2003-07-26 2003-08-27 Astrazeneca Ab Method
ES2544692T3 (es) * 2003-08-29 2015-09-02 Instituto Nacional De Tecnología Agropecuaria Plantas de arroz que tienen tolerancia aumentada a herbicidas de imidazolinona
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
JP4435174B2 (ja) 2003-12-02 2010-03-17 エフ．ホフマン−ラ ロシュ アーゲー 重亜硫酸塩処理の改良された方法
US7129049B2 (en) 2003-12-22 2006-10-31 Regents Of The University Of Minnesota Method of detecting equine glycogen storage disease IV
US7432082B2 (en) * 2004-03-22 2008-10-07 Basf Ag Methods and compositions for analyzing AHASL genes
EP1727911B1 (en) 2004-03-26 2013-01-23 Sequenom, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
US7608394B2 (en) 2004-03-26 2009-10-27 Sequenom, Inc. Methods and compositions for phenotype identification based on nucleic acid methylation
US20050287558A1 (en) 2004-05-05 2005-12-29 Crooke Rosanne M SNPs of apolipoprotein B and modulation of their expression
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
US7932026B2 (en) 2004-06-04 2011-04-26 Genentech, Inc. EGFR mutations
WO2006005081A2 (en) * 2004-06-30 2006-01-12 Applera Corporation Compositions and methods for identifying nucleotides in polynucleotide sequences
TR200700491T2 (tr) * 2004-07-30 2007-04-24 Basf Agrochemical Products B.V. Herbisitlere dayanıklı ayçiçeği bitkileri, herbisitlere dayanıklı asetohidroksiasit sintaz geniş altünite proteinlerini kodlayan polinükleotidler
US7981607B2 (en) 2004-08-27 2011-07-19 Esoterix Genetic Laboratories LLC Method for detecting recombinant event
EP1632578A1 (en) 2004-09-03 2006-03-08 Roche Diagnostics GmbH DNA decontamination method
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
JP2006129811A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 試料核酸の分析方法、分析装置および分析キット
US20060105348A1 (en) * 2004-11-15 2006-05-18 Lee Jun E Compositions and methods for the detection and discrimination of nucleic acids
US20060275792A1 (en) * 2004-11-15 2006-12-07 Lee Jun E Enhancement of nucleic acid amplification using double-stranded DNA binding proteins
GB0428255D0 (en) 2004-12-23 2005-01-26 Health Prot Agency Detection of nucleic acid mutations
EP3581024A1 (en) * 2005-03-02 2019-12-18 Instituto Nacional de Tecnologia Agropecuaria Herbicide-resistant rice plants, polynucleotides encoding herbicide-resistant acetohydroxyacid synthase large subunit proteins, and methods of use
GB2424886A (en) 2005-04-04 2006-10-11 Dxs Ltd Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations
EP1871796A4 (en) 2005-04-20 2009-01-14 Auckland Uniservices Ltd VESICULINE
WO2007044071A2 (en) 2005-04-21 2007-04-19 Exact Sciences Corporation Analysis of heterogeneous nucleic acid samples
TR200907590T2 (tr) * 2005-07-01 2010-06-21 Basf Se Herbisitlere dayanıklı ayçiçeği bitkileri herbisitlere dayanıklı asetohidroksiasit sintaz geniş altünite proteinlerini kodlayan polinükleotidler ve kullanma metotları.
GB0514913D0 (en) * 2005-07-20 2005-08-24 Univ Birmingham Polymorphism
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
JP5825754B2 (ja) 2006-05-05 2015-12-02 アイシス ファーマシューティカルズ， インコーポレーテッド Ａｐｏｂの発現を調節するための化合物および方法
US7759062B2 (en) 2006-06-09 2010-07-20 Third Wave Technologies, Inc. T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
KR100812259B1 (ko) * 2006-06-12 2008-03-10 주식회사 씨젠 기지의 서열에 인접한 미지의 ｄｎａ 서열을 증폭하는 방법
US20100159450A1 (en) 2006-06-23 2010-06-24 Susanne Wagner Dpyd gene variants and use thereof
CA2662591A1 (en) 2006-09-07 2008-03-13 Astrazenca Ab Method for evaluating patients for treatment with drugs targeting ret receptor tyrosine kinase
US8580945B2 (en) * 2006-11-02 2013-11-12 University Of Utah Oligonucleotides for use in allele-specific PCR
UA108733C2 (uk) 2006-12-12 2015-06-10 Толерантна до гербіциду рослина соняшника
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
WO2008094370A2 (en) 2006-12-22 2008-08-07 University Of Utah Research Foundation Method of detecting ocular diseases and pathologic conditions and treatment of same
US8314220B2 (en) * 2007-01-26 2012-11-20 Agilent Technologies, Inc. Methods compositions, and kits for detection of microRNA
CN103480002A (zh) 2007-03-24 2014-01-01 基酶有限公司 施用与人载脂蛋白 b互补的反义寡核苷酸
US10017827B2 (en) 2007-04-04 2018-07-10 Nidera S.A. Herbicide-resistant sunflower plants with multiple herbicide resistant alleles of AHASL1 and methods of use
ES2529790T3 (es) 2007-04-13 2015-02-25 Dana-Farber Cancer Institute, Inc. Métodos de tratamiento de cáncer resistente a agentes terapéuticos de ERBB
BRPI0810917A2 (pt) 2007-05-03 2014-10-29 One Lambda Inc Métodos do exame para interação obrigatória usando jogos das micropartículas e de pontas de prova originais
CN108753946A (zh) 2007-05-21 2018-11-06 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
US20100203051A1 (en) 2007-05-31 2010-08-12 The University Of Queensland Diagnostic markers for ankylosing spondylitis and uses thereof
WO2008153804A2 (en) * 2007-05-31 2008-12-18 Monsanto Technology Llc Soybean polymorphisms and methods of genotyping
US8420315B2 (en) 2007-08-06 2013-04-16 Orion Genomics Llc Single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene
CL2008002553A1 (es) 2007-08-29 2009-09-04 Monsanto Technology Llc Metodo de mejoramiento de plantas mediante la introduccion de loci de caracteristicas cuantitativas asociadas con resistencia a la mancha foliar gris.
JP2009077712A (ja) 2007-09-11 2009-04-16 F Hoffmann La Roche Ag Ｂ−Ｒａｆキナーゼ阻害剤に対する感受性についての診断試験
GB2453173A (en) 2007-09-28 2009-04-01 Dxs Ltd Polynucleotide primers
EP2851432B1 (en) 2007-11-01 2019-01-09 University of Iowa Research Foundation RCA locus analysis to assess susceptibility to AMD
EP2218019A4 (en) * 2007-11-02 2012-04-18 Hunch Inc INTERACTIVE AUTOMATIC LEARNING ADVICE INSTALLATION
CA2704487A1 (en) * 2007-11-02 2009-06-18 Luminex Molecular Diagnostics, Inc. One-step target detection assay
JP5188789B2 (ja) * 2007-11-29 2013-04-24 株式会社日立製作所 核酸の定量方法
WO2009098998A1 (ja) 2008-02-05 2009-08-13 Olympus Corporation 核酸検出方法及び核酸検出用キット
WO2009132089A2 (en) 2008-04-24 2009-10-29 Monsanto Technology Llc A method to identify asian soybean rust resistance quantitative trait loci in soybean and compositions thereof
EP2113574A1 (en) 2008-04-28 2009-11-04 Biotype AG Substances and methods for a DNA based profiling assay
EP2279263B1 (en) 2008-04-30 2013-09-04 Integrated Dna Technologies, Inc. Rnase-h-based assays utilizing modified rna monomers
US8911948B2 (en) * 2008-04-30 2014-12-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
JP5637850B2 (ja) 2008-07-02 2014-12-10 アークレイ株式会社 標的核酸配列の増幅方法、それを用いた変異の検出方法、および、それに用いる試薬
JP5590781B2 (ja) 2008-07-10 2014-09-17 オリンパス株式会社 標的核酸比率推定方法
JP5624044B2 (ja) * 2008-10-20 2014-11-12 エフ．ホフマン−ラ ロシュアーゲーＦ．Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 改善されたアレル−特異的増幅
EP2186907A1 (en) 2008-11-11 2010-05-19 Deutsches Primatenzentrum GmbH X-chromosomal variation as a diagnostic and therapeutic marker for the progression to AIDS
DK3301446T3 (da) 2009-02-11 2020-06-29 Caris Mpi Inc Molekylær tumorprofilering
AU2010213727A1 (en) 2009-02-11 2011-09-29 Orion Genomics Llc Combinations of polymorphisms for determining allele-specific expression of IGF2
JP5457222B2 (ja) 2009-02-25 2014-04-02 エフ．ホフマン−ラ ロシュ アーゲー 小型化ハイスループット核酸分析
US9347092B2 (en) * 2009-02-25 2016-05-24 Roche Molecular System, Inc. Solid support for high-throughput nucleic acid analysis
EP2408796B1 (en) 2009-03-16 2020-04-22 Ionis Pharmaceuticals, Inc. Targeting Apolipoprotein B for the reduction of Apolipoprotein C-III
SG174904A1 (en) 2009-03-25 2011-11-28 Genentech Inc Anti-fgfr3 antibodies and methods using same
WO2010112033A2 (en) 2009-03-31 2010-10-07 Østjysk Innovation A/S Method for estimating the risk of having or developing multiple sclerosis using sequence polymorphisms in a specific region of chromosome x
US20100299773A1 (en) * 2009-05-20 2010-11-25 Monsanto Technology Llc Methods and compositions for selecting an improved plant
JP5785942B2 (ja) * 2009-06-29 2015-09-30 ルミネックス コーポレーション ヘアピンコンフォメーションを有するキメラプライマーおよびその使用法
BR112012007778A2 (pt) 2009-10-07 2020-08-11 Genentech, Inc. método para identificar lúpus, método para avaliar se um sujeito está em risco de desenvolver lúpus, medicamentos para tratar uma condição de lupus, método e usos de um agente terapêutico.
WO2011056688A2 (en) 2009-10-27 2011-05-12 Caris Life Sciences, Inc. Molecular profiling for personalized medicine
WO2011056687A2 (en) 2009-10-27 2011-05-12 Swift Biosciences, Inc. Polynucleotide primers and probes
US9238832B2 (en) 2009-12-11 2016-01-19 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids
US8614071B2 (en) 2009-12-11 2013-12-24 Roche Molecular Systems, Inc. Preferential amplification of mRNA over DNA using chemically modified primers
EP2450443B1 (en) 2010-01-21 2016-05-11 ARKRAY, Inc. Target sequence amplification method, polymorphism detection method, and reagents for use in the methods
WO2011128096A1 (en) 2010-04-16 2011-10-20 Roche Diagnostics Gmbh Polymorphism markers for predicting response to interleukin-6 receptor-inhibiting monoclonal antibody drug treatment
EP2383348B1 (en) 2010-04-30 2015-03-04 ARKRAY, Inc. Method for adjusting amplification efficiency of target polynucleotide
US9340833B2 (en) 2010-04-30 2016-05-17 Arkray, Inc. Method for adjusting amplification efficiency of target polynucleotide
GB201008125D0 (en) 2010-05-14 2010-06-30 Biofortuna Ltd Tissue typing assays and kits
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
WO2012071096A2 (en) 2010-09-03 2012-05-31 The Johns Hopkins University Arid1a and ppp2r1a mutations in cancer
WO2012052758A1 (en) 2010-10-22 2012-04-26 Astrazeneca Ab Response biomarkers for iap antagonists in human cancers
US9528157B2 (en) 2011-01-14 2016-12-27 Genefirst Limited Methods, compositions, and kits for determing the presence/absence of a variant nucleic acid sequence
GB201101200D0 (en) 2011-01-24 2011-03-09 King S College Method
JP6153874B2 (ja) 2011-02-09 2017-06-28 ナテラ， インコーポレイテッド 非侵襲的出生前倍数性呼び出しのための方法
WO2012135053A2 (en) 2011-03-25 2012-10-04 Integrated Dna Technologies, Inc. Rnase h-based assays utilizing modified rna monomers
RU2635193C2 (ru) 2011-04-01 2017-11-09 Дженентек, Инк. Биомаркеры для прогнозирования чувствительности к противоопухолевой терапии
WO2012149193A2 (en) 2011-04-29 2012-11-01 Monsanto Technology Llc Diagnostic molecular markers for seed lot purity traits in soybeans
BR112013028306B1 (pt) 2011-05-02 2020-04-07 Univ Nebraska plantas com características úteis e processos relacionados
EP2751280B1 (en) 2011-08-31 2016-06-29 F.Hoffmann-La Roche Ag Method for predicting risk of hypertension associated with anti-angiogenesis therapy
JP2014526900A (ja) 2011-08-31 2014-10-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 血管新生阻害剤に対する応答性
ES2727672T3 (es) 2011-08-31 2019-10-17 Seminis Vegetable Seeds Inc Procedimientos y composiciones para la firmeza de la sandía
KR20140064971A (ko) 2011-09-19 2014-05-28 제넨테크, 인크. c-met 길항제 및 B-raf 길항제를 포함하는 조합 치료
CA2850032C (en) 2011-10-14 2022-06-07 Genentech, Inc. Anti-htra1 antibodies and methods of use
JP6338530B2 (ja) 2011-11-10 2018-06-06 ジェネンテック， インコーポレイテッド アルツハイマー病を治療、診断、および監視するための方法
AU2012342682A1 (en) 2011-11-23 2014-05-22 F. Hoffmann-La Roche Ag Responsiveness to angiogenesis inhibitors
EP2785864A2 (en) 2011-11-30 2014-10-08 F. Hoffmann-La Roche AG Erbb3 mutations in cancer
JP2015501652A (ja) 2011-12-14 2015-01-19 アストラゼネカ・アクチエボラーグＡｓｔｒａｚｅｎｅｃａ Ａｋｔｉｅｂｏｌａｇ Ｇａｂｒ−ａ２診断
EP2607495A1 (en) 2011-12-23 2013-06-26 Genomica S.A.U. Method for detection of KRAS mutations
US10633707B2 (en) 2012-04-10 2020-04-28 Vib Vzw Markers for detecting microsatellite instability in cancer and determining synthetic lethality with inhibition of the DNA base excision repair pathway
US10294529B2 (en) 2012-04-10 2019-05-21 Life Sciences Research Partners Vzw Microsatellite instability markers in detection of cancer
US10385396B2 (en) 2012-04-19 2019-08-20 The Medical College Of Wisconsin, Inc. Highly sensitive surveillance using detection of cell free DNA
US10077474B2 (en) 2012-05-29 2018-09-18 Abbott Molecular, Inc. Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
EP2711432A1 (en) 2012-09-21 2014-03-26 Genomica S.A.U. Method for detection of BRAF and PI3K mutations
US10314253B2 (en) 2012-12-04 2019-06-11 Seminis Vegetable Seeds, Inc. Methods and compositions for watermelon sex expression
CA2901126C (en) 2013-02-25 2022-01-25 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant
US20140272956A1 (en) 2013-03-15 2014-09-18 Abbott Molecular Inc. Method for amplification and assay of rna fusion gene variants, method of distinguishing same and related primers, probes, and kits
WO2014149356A1 (en) 2013-03-15 2014-09-25 Abbott Molecular Inc. Detection of bisulfite converted nucleotide sequences
US10294489B2 (en) 2013-03-15 2019-05-21 Board Of Trustees Of Southern Illinois University Soybean resistant to cyst nematodes
SG11201507739TA (en) 2013-03-19 2015-10-29 Toppan Printing Co Ltd Method for predicting sensitivity to egfr inhibitor
US10059999B2 (en) 2013-06-10 2018-08-28 Monsanto Technology Llc Molecular markers associated with soybean tolerance to low iron growth conditions
US10767188B2 (en) 2013-09-25 2020-09-08 Nutech Ventures Methods and compositions for obtaining useful plant traits
NZ630628A (en) 2013-10-08 2015-04-24 Seminis Vegetable Seeds Inc Methods and compositions for peronospora resistance in spinach
JP2015096049A (ja) 2013-11-15 2015-05-21 凸版印刷株式会社 Ｖｅｇｆ阻害剤長期奏功性予測方法
NZ735461A (en) 2013-11-27 2020-05-29 Seminis Vegetable Seeds Inc Disease resistance loci in onion
PT3632202T (pt) 2014-02-21 2022-10-03 Syngenta Participations Ag Locais genéticos associados a fertilidade acrescida em milho
NZ630710A (en) 2014-02-27 2016-03-31 Seminis Vegetable Seeds Inc Compositions and methods for peronospora resistance in spinach
SG11201607772WA (en) 2014-03-31 2016-10-28 Debiopharm Int Sa Fgfr fusions
US20180173846A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
TW201620526A (zh) * 2014-06-17 2016-06-16 愛羅海德研究公司 用於抑制α－１抗胰蛋白酶基因表現之組合物及方法
US10316369B2 (en) 2014-06-27 2019-06-11 Seminis Vegetable Seeds, Inc. Methods and assays for male sterile watermelon
CN113016623A (zh) 2014-09-26 2021-06-25 谱赛科美国股份有限公司 用于甜菊的单核苷酸多态性(snp)标志物
EP3005862A1 (en) 2014-10-10 2016-04-13 Seminis Vegetable Seeds, Inc. Melon plants with improved disease tolerance
KR20170080675A (ko) 2014-11-05 2017-07-10 제넨테크, 인크. 항-fgfr2/3 항체 및 이의 이용 방법
US20160168640A1 (en) 2014-11-10 2016-06-16 Genentech, Inc. Therapeutic and diagnostic methods for il-33-mediated disorders
US9909169B2 (en) 2014-12-17 2018-03-06 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids using blocking oligonucleotides for wild type suppression
EP3289087B1 (en) 2015-04-28 2021-02-24 Monsanto Technology LLC Methods and compositions for producing brachytic corn plants
UA126326C2 (uk) 2015-04-30 2022-09-21 Монсанто Текнолоджі Елелсі Спосіб відбору рослини каноли, стійкої до кили капустяних
DK3294906T3 (en) 2015-05-11 2024-08-05 Natera Inc Methods for determining ploidy
AU2016308049B2 (en) 2015-08-18 2022-03-17 Monsanto Technology Llc Methods for producing cotton plants with enhanced drought tolerance and compositions thereof
US10448595B2 (en) 2015-09-03 2019-10-22 Seminis Vegetable Seeds, Inc. Downy mildew resistant lettuce plants
US10858709B2 (en) 2015-09-10 2020-12-08 Monsanto Technology Llc Methods for producing corn plants with downy mildew resistance and compositions thereof
RU2750285C2 (ru) 2015-10-30 2021-06-25 Дженентек, Инк. АНТИТЕЛА ПРОТИВ НtrА1 И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
EP3389362A4 (en) 2015-12-18 2019-08-07 Monsanto Technology LLC METHOD FOR THE PRODUCTION OF PIPES WITH RESISTANCE TO THE NORTHIAN LEAF AND COMPOSITIONS THEREOF
CN109477138A (zh) 2016-04-15 2019-03-15 纳特拉公司 肺癌检测方法
EP3496528A4 (en) 2016-08-11 2020-03-18 Monsanto Technology LLC METHODS AND COMPOSITIONS FOR PRODUCING CORN PLANTS WITH RESISTANCE TO LATE FAILURE
AU2017312113B2 (en) * 2016-08-17 2023-05-25 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
AU2017232187B2 (en) 2016-09-30 2023-11-09 Seminis Vegetable Seeds, Inc. Xanthomonas resistant brassica oleracea plants
GB201618485D0 (en) 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence
EP3535391A4 (en) * 2016-11-02 2020-05-13 The Medical College of Wisconsin, Inc. RISK ASSESSMENT METHODS USING MISMATCHING AMPLIFICATION AND STATISTICAL METHODS
US11031099B2 (en) 2016-11-09 2021-06-08 Roche Molecular Systems, Inc. Detection of sequence variants
WO2018118808A1 (en) 2016-12-19 2018-06-28 The Broad Institute, Inc. Methods of treating autism spectrum disorders
WO2018170436A1 (en) 2017-03-16 2018-09-20 Jacobs Farm Del Cabo Basil with high tolerance to downy mildew
JP2020517273A (ja) 2017-04-24 2020-06-18 ジェネンテック， インコーポレイテッド 膜貫通ドメインまたは膜近傍ドメインにおけるＥｒｂＢ２／Ｈｅｒ２突然変異
KR102640361B1 (ko) 2017-05-17 2024-02-23 마이크로바이오 피티와이 엘티디 바이오마커 및 그의 용도
EP3642353B1 (en) 2017-06-20 2025-03-05 The Medical College of Wisconsin, Inc. Assessing transplant complication risk with total cell-free dna
JP6986299B2 (ja) 2017-07-12 2021-12-22 ジーンキャスト カンパニー リミテッドGenecast Co., Ltd. 遺伝子変異特異性が増加したｄｎａ重合酵素およびその活性増加用ｐｃｒバッファー組成物
WO2019118652A1 (en) 2017-12-12 2019-06-20 Essenlix Corporation Sample manipulation and assay with rapid temperature change
US12084720B2 (en) 2017-12-14 2024-09-10 Natera, Inc. Assessing graft suitability for transplantation
WO2019157358A1 (en) 2018-02-09 2019-08-15 Genentech, Inc. Therapeutic and diagnostic methods for mast cell-mediated inflammatory diseases
CN112236535A (zh) 2018-04-14 2021-01-15 纳特拉公司 用于借助于循环肿瘤dna的个人化检测的癌症检测和监测的方法
US11268102B2 (en) 2018-05-16 2022-03-08 University Of Florida Research Foundation, Incorporated Compositions and methods for identifying and selecting brachytic locus in solanaceae
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
AU2019389175B2 (en) 2018-11-30 2025-03-06 Caris Mpi, Inc. Next-generation molecular profiling
WO2020150144A1 (en) 2019-01-15 2020-07-23 Seminis Vegetable Seeds, Inc. Green bean plants with improved disease resistance
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
EP3998083A4 (en) 2019-07-12 2023-08-23 Chugai Seiyaku Kabushiki Kaisha Anti-mutation type fgfr3 antibody and use therefor
SG10202008262UA (en) 2019-09-26 2021-04-29 Seminis Vegetable Seeds Inc Lettuce plants having resistance to nasonovia ribisnigri biotype nr:1
EP4069865A4 (en) 2019-12-02 2023-12-20 Caris MPI, Inc. PLATINUM RESPONSE PREDICTOR IN A PAN-CANCER APPROACH
JP2023517078A (ja) 2020-03-11 2023-04-21 シージェン インコーポレイテッド ツカチニブを用いてｈｅｒ２突然変異を有するがんを処置する方法
US20230110203A1 (en) 2020-03-13 2023-04-13 Medimmune Limited Therapeutic methods for the treatment of subjects with risk alelles in il33
AU2021204717A1 (en) 2020-07-15 2022-02-03 Seminis Vegetable Seeds, Inc. Green Bean Plants with Improved Disease Resistance
CN116437924A (zh) 2020-09-28 2023-07-14 思进股份有限公司 用妥卡替尼与抗her2抗体的组合治疗her2改变驱动的实体瘤的方法
US20240024320A1 (en) 2020-11-17 2024-01-25 Seagen Inc. Methods of treating cancer with a combination of tucatinib and an anti-pd-1/anti-pd-l1 antibody
US20230193310A1 (en) 2021-12-10 2023-06-22 Seminis Vegetabe Seeds, Inc. Lettuce plants having resistance to downy mildew
WO2023250288A2 (en) 2022-06-21 2023-12-28 Seminis Vegetable Seeds, Inc. Novel qtls conferring resistance to cucumber mosaic virus
US20240344079A1 (en) 2023-04-14 2024-10-17 Seminis Vegetable Seeds, Inc. Methods and compositions for peronospora resistance in spinach
WO2024231499A1 (en) 2023-05-10 2024-11-14 Vib Vzw Combinations of short genetic variants in the diagnosis of alzheimer disease

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311018D0 (en) * 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
GB8612087D0 (en) * 1986-05-19 1986-06-25 Ici Plc Hybridisation probes
GB8709652D0 (en) * 1987-04-23 1987-05-28 Williamson R Diagnosis of cystic fibrosis
US4994368A (en) * 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
EP0317239A3 (en) * 1987-11-13 1990-01-17 Native Plants Incorporated Method and device for improved restriction fragment length polymorphism analysis
AU613989B2 (en) * 1987-11-24 1991-08-15 Gen-Probe Incorporated Means and method for enhancing nucleic acid hybridization
AU2735988A (en) * 1987-12-21 1989-07-13 Amoco Corporation Target and background capture methods with amplification for affinity assays
US4999290A (en) * 1988-03-31 1991-03-12 The Board Of Regents, The University Of Texas System Detection of genomic abnormalities with unique aberrant gene transcripts
AU3694689A (en) * 1988-04-28 1989-11-24 Mark H. Skolnick Amplified sequence polymorphisms (asps)
AU629845B2 (en) * 1988-08-30 1992-10-15 Abbott Laboratories Detection and amplification of target nucleic acid sequences
CA1339731C (en) * 1988-10-12 1998-03-17 Charles T. Caskey Multiplex genomic dna amplification for deletion detection
CA2011818A1 (en) * 1989-03-17 1990-09-17 Fred T. Oakes Methods for purification, amplification and detection of a nucleic acid
WO1990011372A1 (en) * 1989-03-21 1990-10-04 Collaborative Research, Inc. Multiplex dna diagnostic test
CA2013317A1 (en) * 1989-04-17 1990-10-17 Fred T. Oakes Diagnostic kit, primer composition and their use for replication or detection of nucleic acids
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer

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