SG11201507739TA - Method for predicting sensitivity to egfr inhibitor - Google Patents
Method for predicting sensitivity to egfr inhibitorInfo
- Publication number
- SG11201507739TA SG11201507739TA SG11201507739TA SG11201507739TA SG11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA
- Authority
- SG
- Singapore
- Prior art keywords
- egfr inhibitor
- predicting sensitivity
- predicting
- sensitivity
- egfr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013057033 | 2013-03-19 | ||
PCT/JP2014/057556 WO2014148557A1 (en) | 2013-03-19 | 2014-03-19 | Method for predicting sensitivity to egfr inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507739TA true SG11201507739TA (en) | 2015-10-29 |
Family
ID=51580231
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507739TA SG11201507739TA (en) | 2013-03-19 | 2014-03-19 | Method for predicting sensitivity to egfr inhibitor |
SG10201707548RA SG10201707548RA (en) | 2013-03-19 | 2014-03-19 | Method for predicting sensitivity to egfr inhibitor |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201707548RA SG10201707548RA (en) | 2013-03-19 | 2014-03-19 | Method for predicting sensitivity to egfr inhibitor |
Country Status (6)
Country | Link |
---|---|
US (1) | US20160002741A1 (en) |
EP (1) | EP2977464A4 (en) |
JP (1) | JP6520705B2 (en) |
CN (1) | CN105074009B (en) |
SG (2) | SG11201507739TA (en) |
WO (1) | WO2014148557A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012129363A2 (en) | 2011-03-24 | 2012-09-27 | President And Fellows Of Harvard College | Single cell nucleic acid detection and analysis |
US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
PT2893040T (en) | 2012-09-04 | 2019-04-01 | Guardant Health Inc | Systems and methods to detect rare mutations and copy number variation |
US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
JP2015096049A (en) * | 2013-11-15 | 2015-05-21 | 凸版印刷株式会社 | Method for predicting long-term success of vegf inhibitor |
ES2822125T3 (en) | 2013-12-28 | 2021-04-29 | Guardant Health Inc | Methods and systems to detect genetic variants |
WO2016103727A1 (en) * | 2014-12-25 | 2016-06-30 | 凸版印刷株式会社 | Method for promoting amplification of specific nucleic acid sequence |
CN108603228B (en) | 2015-12-17 | 2023-09-01 | 夸登特健康公司 | Method for determining tumor gene copy number by analyzing cell-free DNA |
WO2017110764A1 (en) * | 2015-12-24 | 2017-06-29 | 公益財団法人がん研究会 | Test method for predicting effectiveness and safety of multi-kinase inhibitor, test kit, and biomarker |
CN109072228A (en) | 2016-04-28 | 2018-12-21 | 电化株式会社 | Determine cancer cell for the method for the patience of epidermal growth factor receptor inhibitor |
JP2019202936A (en) * | 2016-08-17 | 2019-11-28 | 中外製薬株式会社 | Combination drug of anti-Epiregulin antibody and anti-EGFR antibody |
WO2018131705A1 (en) * | 2017-01-16 | 2018-07-19 | 凸版印刷株式会社 | Method of detecting somatic mutations in tumor marker genes, and tumor status evaluation method |
CN111032092A (en) * | 2017-06-30 | 2020-04-17 | 韩国科学技术院 | Conjugates of VEGF-GRAB proteins and drugs and uses thereof |
CN111278992A (en) * | 2017-08-30 | 2020-06-12 | 西福根有限公司 | Compositions and methods for treating cancer with anti-EGFR antibodies |
CN108998535B (en) * | 2018-09-11 | 2021-09-10 | 广州市宝创生物技术有限公司 | KRAS gene multiple mutation site detection kit |
IL293340A (en) | 2019-12-02 | 2022-07-01 | Storm Therapeutics Ltd | Polyheterocyclic compounds as mettl3 inhibitors |
CN112162042B (en) * | 2020-09-14 | 2022-04-26 | 首都医科大学附属北京朝阳医院 | Method for measuring AMG510 concentration in plasma by ultra performance liquid chromatography tandem mass spectrometry |
CN116997358A (en) * | 2021-03-09 | 2023-11-03 | 詹森生物科技公司 | Treatment of cancers lacking EGFR activating mutations |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4943533A (en) | 1984-03-01 | 1990-07-24 | The Regents Of The University Of California | Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor |
IE61148B1 (en) | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
US5679683A (en) | 1994-01-25 | 1997-10-21 | Warner-Lambert Company | Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
RS53265B2 (en) * | 2007-03-13 | 2022-06-30 | Amgen Inc | K-ras mutations and anti-egfr antibody therapy |
CL2008000716A1 (en) * | 2007-03-13 | 2008-09-22 | Amgen Inc | METHOD FOR FORECASTING IF A PATIENT WILL BE NOT RESPONDING TO THE TREATMENT WITH A SPECIFIC UNION AGENT TO AN EGFR POLYPEPTIDE THAT INCLUDES DETERMINING THE PRESENCE OR ABSENCE OF A K-RAS AND B-RAF MUTATION IN A PATIENT TUMOR. |
GB2480980A (en) * | 2009-03-02 | 2011-12-07 | Trackfive Diagnostics Inc | Methods for predicting cancer response to EGFR inhibitors |
JP2012135290A (en) * | 2010-12-28 | 2012-07-19 | Fuaruko Bio Syst:Kk | Method of evaluating treatment sensitivity of molecularly targeted drug using high-sensitivity k-ras gene mutation analysis |
US20140134158A1 (en) * | 2012-05-22 | 2014-05-15 | Alberto Bardelli | Kras mutations and resistance to anti-egfr treatment |
-
2014
- 2014-03-19 CN CN201480017000.0A patent/CN105074009B/en active Active
- 2014-03-19 JP JP2015506829A patent/JP6520705B2/en active Active
- 2014-03-19 SG SG11201507739TA patent/SG11201507739TA/en unknown
- 2014-03-19 WO PCT/JP2014/057556 patent/WO2014148557A1/en active Application Filing
- 2014-03-19 EP EP14767593.8A patent/EP2977464A4/en not_active Withdrawn
- 2014-03-19 SG SG10201707548RA patent/SG10201707548RA/en unknown
-
2015
- 2015-09-17 US US14/857,187 patent/US20160002741A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP6520705B2 (en) | 2019-05-29 |
CN105074009B (en) | 2017-09-26 |
EP2977464A4 (en) | 2016-10-19 |
EP2977464A1 (en) | 2016-01-27 |
CN105074009A (en) | 2015-11-18 |
WO2014148557A1 (en) | 2014-09-25 |
SG10201707548RA (en) | 2017-10-30 |
JPWO2014148557A1 (en) | 2017-02-16 |
US20160002741A1 (en) | 2016-01-07 |
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