SK286451B6 - Perorálna pevná kompozícia obsahujúca entakapon, levodopu a karbidopu a spôsoby jej prípravy a použitie - Google Patents

Perorálna pevná kompozícia obsahujúca entakapon, levodopu a karbidopu a spôsoby jej prípravy a použitie Download PDF

Info

Publication number
SK286451B6
SK286451B6 SK1923-2001A SK19232001A SK286451B6 SK 286451 B6 SK286451 B6 SK 286451B6 SK 19232001 A SK19232001 A SK 19232001A SK 286451 B6 SK286451 B6 SK 286451B6
Authority
SK
Slovakia
Prior art keywords
carbidopa
entacapone
levodopa
pharmaceutically acceptable
composition
Prior art date
Application number
SK1923-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK19232001A3 (sk
Inventor
Sari Kallioinen
Lasse Kervinen
Marja Laaksonen
Jarmo Lintulaakso
Mervi Niskanen
Marja Partanen
Marja Ritala
Kari Vahervuo
Matti Virkki
Original Assignee
Orion Corporation - Bic 1999212-6
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8554988&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK286451(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Corporation - Bic 1999212-6 filed Critical Orion Corporation - Bic 1999212-6
Publication of SK19232001A3 publication Critical patent/SK19232001A3/sk
Publication of SK286451B6 publication Critical patent/SK286451B6/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SK1923-2001A 1999-06-30 2000-06-29 Perorálna pevná kompozícia obsahujúca entakapon, levodopu a karbidopu a spôsoby jej prípravy a použitie SK286451B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI991485A FI109453B (fi) 1999-06-30 1999-06-30 Farmaseuttinen koostumus
PCT/FI2000/000593 WO2001001984A1 (en) 1999-06-30 2000-06-29 Levodopa / carbidopa / entacapone pharmaceutical preparation

Publications (2)

Publication Number Publication Date
SK19232001A3 SK19232001A3 (sk) 2002-06-04
SK286451B6 true SK286451B6 (sk) 2008-10-07

Family

ID=8554988

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1923-2001A SK286451B6 (sk) 1999-06-30 2000-06-29 Perorálna pevná kompozícia obsahujúca entakapon, levodopu a karbidopu a spôsoby jej prípravy a použitie

Country Status (42)

Country Link
US (2) US6500867B1 (cs)
EP (1) EP1189608B1 (cs)
JP (2) JP4204783B2 (cs)
KR (1) KR100905428B1 (cs)
CN (1) CN1168440C (cs)
AR (1) AR033796A1 (cs)
AT (1) ATE245417T1 (cs)
AU (1) AU765932B2 (cs)
BG (1) BG65364B1 (cs)
BR (2) BR0011867A (cs)
CA (1) CA2378469C (cs)
CO (1) CO5180579A1 (cs)
CZ (2) CZ304416B6 (cs)
DE (1) DE60004052T2 (cs)
DK (1) DK1189608T3 (cs)
EA (1) EA004503B1 (cs)
EE (1) EE05473B1 (cs)
ES (1) ES2203495T3 (cs)
FI (1) FI109453B (cs)
FR (1) FR2797587A1 (cs)
GE (1) GEP20043314B (cs)
HK (1) HK1047040B (cs)
HR (1) HRP20020088B1 (cs)
HU (1) HU230395B1 (cs)
IL (1) IL146807A (cs)
IT (1) ITMI20001450A1 (cs)
ME (1) ME00520B (cs)
MX (1) MXPA01013167A (cs)
MY (1) MY127685A (cs)
NO (2) NO330260B1 (cs)
NZ (1) NZ515780A (cs)
PE (1) PE20010399A1 (cs)
PL (1) PL197818B1 (cs)
PT (1) PT1189608E (cs)
RS (1) RS50368B (cs)
SI (1) SI1189608T1 (cs)
SK (1) SK286451B6 (cs)
TR (1) TR200103763T2 (cs)
TW (1) TWI241187B (cs)
UA (1) UA75047C2 (cs)
WO (1) WO2001001984A1 (cs)
ZA (1) ZA200109868B (cs)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI109453B (fi) 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
US7094427B2 (en) * 2002-05-29 2006-08-22 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
US20040166159A1 (en) * 2002-05-29 2004-08-26 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa
US20030224045A1 (en) * 2002-05-29 2003-12-04 Chien-Hsuan Han Combination immediate release sustained release levodopa/carbidopa dosage forms
US20060013875A1 (en) * 2002-05-29 2006-01-19 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
US20050147670A1 (en) * 2002-05-29 2005-07-07 Impax Laboratories Inc. Oral disintegrating dosage forms
US20040006072A1 (en) * 2002-06-25 2004-01-08 Franz Robert M. Sustained-release alprazolam composition
EP1560569A4 (en) * 2002-10-11 2006-03-22 Depomed Dev Ltd GASTRORETENTIVE LEVODOPA DELIVERY FORM
AR044007A1 (es) 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
EP1588704A1 (en) * 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of restless legs syndrome and addictive disorders
SE0401842D0 (sv) * 2004-07-12 2004-07-12 Dizlin Medical Design Ab Infusion and injection solution of levodopa
US20060241183A1 (en) * 2004-09-28 2006-10-26 Farouk Karoum Compositions and methods of using D-DOPA to treat Parkinson's disease
US20060173074A1 (en) 2004-11-10 2006-08-03 Juha Ellmen Treatment of restless legs syndrome
AU2012216377C1 (en) * 2005-06-08 2013-10-10 Orion Corporation Oral dosage form
CA2611114C (en) * 2005-06-08 2014-09-23 Orion Corporation An entacapone-containing oral dosage form
AU2006261893A1 (en) * 2005-06-23 2007-01-04 Combinatorx, Incorporated Improved dosage forms for movement disorder treatment
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
JP5517453B2 (ja) * 2005-07-26 2014-06-11 ノヴィファーマ,エス.アー. Comt阻害剤
WO2007016190A2 (en) * 2005-07-28 2007-02-08 Duke University Antiparkinsonian action of phenylisopropylamines
WO2007034024A2 (en) * 2005-09-21 2007-03-29 Orion Corporation Treatment of symptoms of parkinson' s disease
US20070178149A1 (en) * 2005-11-07 2007-08-02 Moshe Flashner-Barak Levodopa compositions
US8772346B2 (en) * 2005-11-09 2014-07-08 Torrent Pharmaceuticals Limited Pharmaceutical composition
GB2429645A (en) * 2006-03-10 2007-03-07 Sekhsaria Chemicals Ltd Solid pharmaceutical composition comprising a COMT inhibitor, a starch and a wetting agent
CN100384411C (zh) * 2006-03-17 2008-04-30 北京科信必成医药科技发展有限公司 卡左双多巴口腔崩解片
WO2007113371A1 (en) * 2006-03-31 2007-10-11 Iprbox Oy Pharmaceutical composition and preparation method thereof
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
EP1870097A1 (en) * 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful in the treatment of cognitive disorders
US8106056B2 (en) * 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
US20080131492A1 (en) * 2006-06-23 2008-06-05 Spherics, Inc. Dosage forms for movement disorder treatment
WO2008053297A2 (en) * 2006-10-30 2008-05-08 Wockhardt Research Centre Pharmaceutical compositions comprising entacapone, levodopa, and carbidopa
AU2007338631A1 (en) * 2006-12-22 2008-07-03 Combinatorx, Incorporated Pharmaceutical compositions for treatment of parkinson's disease and related disorders
WO2008081268A2 (en) * 2006-12-27 2008-07-10 Wockhardt Research Centre Pharmaceutical compositions of entacapone
EP1946756A1 (en) * 2007-01-17 2008-07-23 Revotar Biopharmaceuticals AG Use of entacapone in cosmetic, dermatological and pharmaceutical compositions
CA2678391C (en) 2007-01-31 2017-01-17 David Alexander Learmonth Dosage regimen for comt inhibitors
US20110171275A1 (en) * 2007-08-20 2011-07-14 Team Academy Of Pharmaceutical Science Gastroretentive drug delivery system, preparation method and use thereof
CN101939002B (zh) * 2008-02-06 2012-12-26 沃克哈特研究中心 与糖醇共微粉化的恩他卡朋药物组合物
CN101939003A (zh) 2008-02-06 2011-01-05 沃克哈特研究中心 生物利用度改善的恩他卡朋、左旋多巴与卡比多巴的药物组合物
RU2010139315A (ru) 2008-03-17 2012-04-27 Биал - Портела Энд Ка., С.А. (Pt) Кристаллические формы 5-[3-(2,5-дихлор-4,6-диметил-1-окси-пиридин-3-ил)[1,2,4]оксадиазол-5-ил]-3-нитробензол-1,2-диола
KR20110046555A (ko) * 2008-08-22 2011-05-04 욱크하르트 리서치 센터 레보도파, 카비도파 및 엔타카폰 또는 이의 염을 포함하는 단일 단위 경구 투여 약학 조성물
WO2010020969A1 (en) * 2008-08-22 2010-02-25 Wockhardt Research Centre An extended release pharmaceutical composition of entacapone or salts thereof
TR200806646A2 (tr) * 2008-09-03 2009-06-22 Dr. F. Fri̇k İlaç San. Ve Ti̇c. A.Ş. Entakapon, levodopa ve karbidoba içeren farmasötik kombinasyonlar
EP2233131A1 (en) 2009-03-23 2010-09-29 Laboratorios Lesvi, S.L. Pharmaceutical composition containing levodopa, entacapone and carbidopa
PT2413912T (pt) 2009-04-01 2019-06-11 Bial Portela & Ca Sa Formulações farmacêuticas compreendendo derivados de nitrocatecol e métodos para as produzir
HUE052685T2 (hu) 2009-05-19 2021-05-28 Neuroderm Ltd Dopa-dekarboxiláz inhibitorok folyamatos adagolására szolgáló készítmények
EP2517704B1 (en) * 2009-12-25 2019-05-01 Innopharmax, Inc. Pharmaceutical composition for treating parkinson's disease and preparation method thereof
US20130137729A1 (en) * 2010-03-04 2013-05-30 Orion Corporation Use of levodopa, carbidopa and entacapone for treating parkinson's disease
DE102010023828A1 (de) 2010-06-15 2011-12-15 IIP - Institut für industrielle Pharmazie, Forschungs- und Entwicklungsgesellschaft mbH Pharmazeutisches Präparat, welches Entacapon, Levodopa und Carbidopa enthält
BR112013011685B1 (pt) * 2010-11-15 2022-03-03 Neuroderm Ltd Composição líquida farmaceuticamente aceitável e emplastro transdérmico
US20140045900A1 (en) * 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
EP2508174A1 (en) 2011-04-06 2012-10-10 Ljiljana Sovic Brkicic Pharmaceutical composition
WO2012147099A1 (en) * 2011-04-25 2012-11-01 Suven Nishtaa Pharma Pvt. Ltd. Pharmaceutical compositions of levodopa, carbidopa and entacapone
CN103476406B (zh) * 2011-04-26 2017-05-24 因华生技制药股份有限公司 安它可朋组合物
JP6456143B2 (ja) 2011-12-13 2019-01-23 ノヴィファーマ,エス.アー. カテコール−o−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物
TR201204839A2 (tr) 2012-04-25 2012-12-21 Ali̇ Rai̇f İlaç Sanayi̇ A.Ş. Uzatılmış salım sağlayan levodopa karbıdopa entakapon içeren tablet formülasyonu.
EP2854764B1 (en) 2012-06-05 2018-12-12 Neuroderm Ltd Compositions comprising apomorphine and organic acids and uses thereof
SG11201507538UA (en) * 2013-03-13 2015-10-29 Neuroderm Ltd Method for treatment of parkinson's disease
EP2799065A1 (en) * 2013-04-30 2014-11-05 Deva Holding Anonim Sirketi Levodopa carbidopa entacapone pharmaceutical formulations
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
MX369315B (es) 2013-10-07 2019-11-05 Impax Laboratories Inc Formulaciones muco-adhesivas de liberacion controlada de levodopa y/o esteres de levodopa y sus usos.
DK3777833T3 (da) 2014-03-13 2023-12-18 Neuroderm Ltd Dopa-decarboxylase-inhibitorsammensætninger
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
ES2844500T3 (es) 2014-09-04 2021-07-22 Lobsor Pharmaceuticals Ab Composiciones farmacéuticas que comprenden levodopa, un inhibidor de dopamina decarboxilasa y un inhibidor de COMT, y método de administración de las mismas
RU2017120184A (ru) 2014-11-28 2018-12-28 БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. Лекарства для замедления течения болезни паркинсона
WO2016101969A1 (en) 2014-12-23 2016-06-30 Pharmathen S.A. Levodopa/carbidopa/entacapone pharmaceutical preparation and method for preparing the same
US10555922B2 (en) 2015-09-04 2020-02-11 Lobsor Pharmaceuticals Aktiebolag Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor
CN109689036A (zh) * 2016-07-11 2019-04-26 康特拉医药公司 用于治疗早晨运动不能的脉冲药物输送系统
ES2895054T3 (es) 2016-08-18 2022-02-17 Ilko Ilac Sanayi Ve Ticaret Anonim Sirketi Fórmula de comprimido antiparkinson con perfil de disolución mejorado
WO2019145773A1 (en) 2017-12-15 2019-08-01 Nos Life Sciences Corporation Liposomal-encapsulated formulations
KR20200136008A (ko) 2018-03-23 2020-12-04 롭서 파마슈티컬스 악티에볼라그 신경퇴행성 장애의 치료를 위한 약제학적 조성물의 연속 투여
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen
US12194150B2 (en) 2020-12-22 2025-01-14 Amneal Pharmaceuticals Llc Levodopa dosing regimen
US12161612B2 (en) 2023-04-14 2024-12-10 Neuroderm, Ltd. Methods and compositions for reducing symptoms of Parkinson's disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190672A (en) 1978-09-01 1980-02-26 Stanley Fahn Method and compositions of treating Parkinsonisms with levodopa and 3',4'-dihydroxy-2-methylisopropiophenone
GB8521350D0 (en) * 1985-08-28 1985-10-02 Euro Celtique Sa Analgesic composition
US5236952A (en) 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
NZ220599A (en) * 1986-06-16 1990-10-26 Merck & Co Inc Controlled release oral dosage formulation of carbidopa and levodopa
US5283352A (en) 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
DE4101873C2 (de) * 1991-01-23 1993-12-09 Isis Pharma Gmbh Peroral applizierbare Arzneiform zur Behandlung zentraler Dopaminmangelzustände
US5888534A (en) 1995-06-13 1999-03-30 Pentech Pharmaceuticals, Inc. Controlled release of drugs delivered by sublingual or buccal administration
GB2321190B (en) * 1997-01-16 2000-09-20 Britannia Pharmaceuticals Ltd Pharmaceutical composition
US6599530B2 (en) 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives
FI109453B (fi) * 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus

Also Published As

Publication number Publication date
BRPI0011867B1 (pt) 2019-01-08
SK19232001A3 (sk) 2002-06-04
RS50368B (sr) 2009-11-10
HRP20020088A2 (en) 2005-10-31
ZA200109868B (en) 2003-05-28
HK1047040B (zh) 2005-04-29
BG65364B1 (bg) 2008-04-30
CA2378469A1 (en) 2001-01-11
CN1168440C (zh) 2004-09-29
US6797732B2 (en) 2004-09-28
GEP20043314B (en) 2004-02-10
JP2003503454A (ja) 2003-01-28
PE20010399A1 (es) 2001-04-10
NO20110090L (no) 2002-02-25
DK1189608T3 (da) 2003-11-10
FI109453B (fi) 2002-08-15
FI991485A0 (fi) 1999-06-30
HK1047040A1 (en) 2003-02-07
NO20016203L (no) 2002-02-25
DE60004052T2 (de) 2004-04-15
ES2203495T3 (es) 2004-04-16
EP1189608B1 (en) 2003-07-23
DE60004052D1 (de) 2003-08-28
NZ515780A (en) 2004-06-25
EA200200106A1 (ru) 2002-06-27
JP4204783B2 (ja) 2009-01-07
FR2797587A1 (fr) 2001-02-23
WO2001001984A1 (en) 2001-01-11
UA75047C2 (en) 2006-03-15
CZ304416B6 (cs) 2014-04-23
AU765932B2 (en) 2003-10-02
CA2378469C (en) 2009-10-06
US20030017201A1 (en) 2003-01-23
ITMI20001450A1 (it) 2001-12-28
EA004503B1 (ru) 2004-04-29
EE05473B1 (et) 2011-10-17
AU5830600A (en) 2001-01-22
KR20020010155A (ko) 2002-02-02
HUP0202273A3 (en) 2002-11-28
CZ20014636A3 (cs) 2002-05-15
CN1358090A (zh) 2002-07-10
AR033796A1 (es) 2004-01-07
PL352775A1 (en) 2003-09-08
ITMI20001450A0 (it) 2000-06-28
SI1189608T1 (en) 2004-04-30
BR0011867A (pt) 2002-03-05
HUP0202273A2 (en) 2002-10-28
EE200100716A (et) 2003-02-17
HU230395B1 (hu) 2016-04-28
FI991485L (fi) 2000-12-31
CZ303010B6 (cs) 2012-02-29
NO330260B1 (no) 2011-03-14
CO5180579A1 (es) 2002-07-30
ATE245417T1 (de) 2003-08-15
EP1189608A1 (en) 2002-03-27
BRPI0011867B8 (pt) 2021-05-25
ME00520B (me) 2011-10-10
TWI241187B (en) 2005-10-11
TR200103763T2 (tr) 2002-04-22
MY127685A (en) 2006-12-29
PT1189608E (pt) 2003-12-31
US6500867B1 (en) 2002-12-31
HRP20020088B1 (hr) 2007-05-31
JP2008156373A (ja) 2008-07-10
YU92501A (sh) 2004-09-03
BG106251A (en) 2002-08-30
PL197818B1 (pl) 2008-04-30
JP4885896B2 (ja) 2012-02-29
NO20016203D0 (no) 2001-12-18
KR100905428B1 (ko) 2009-06-30
MXPA01013167A (es) 2002-07-02
IL146807A (en) 2006-10-05

Similar Documents

Publication Publication Date Title
SK286451B6 (sk) Perorálna pevná kompozícia obsahujúca entakapon, levodopu a karbidopu a spôsoby jej prípravy a použitie
EP1443917B1 (en) Tamsulosin tablets
RU2485947C2 (ru) Фармацевтические композиции энтакапона, леводопы и карбидопы с улучшенной биодоступностью
JPH0251402B2 (cs)
CN102238941A (zh) 颗粒、制备它们的方法和包含它们的药物产品
KR20150126900A (ko) 데페라시록스의 경구 제제
KR20030009440A (ko) 조성물
JP2022544901A (ja) 4-アミノ-3-置換ブタン酸誘導体の安定化製剤
CN103860550A (zh) 左旋多巴/卡比多巴/罗匹尼罗药物制剂
MXPA06011592A (en) deferasirox DISPERSIBLE TABLETS

Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20200629