SI3098234T1 - Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo - Google Patents

Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo

Info

Publication number
SI3098234T1
SI3098234T1 SI200932205T SI200932205T SI3098234T1 SI 3098234 T1 SI3098234 T1 SI 3098234T1 SI 200932205 T SI200932205 T SI 200932205T SI 200932205 T SI200932205 T SI 200932205T SI 3098234 T1 SI3098234 T1 SI 3098234T1
Authority
SI
Slovenia
Prior art keywords
alpha
sialylation
recombinant fsh
fsh including
including alpha
Prior art date
Application number
SI200932205T
Other languages
English (en)
Slovenian (sl)
Inventor
Ian Cottingham
Daniel Plaksin
Richard Boyd White
Original Assignee
Ferring B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39717519&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI3098234(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferring B.V. filed Critical Ferring B.V.
Publication of SI3098234T1 publication Critical patent/SI3098234T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C12Y204/99006—N-Acetyllactosaminide alpha-2,3-sialyltransferase (2.4.99.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SI200932205T 2008-04-16 2009-04-16 Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo SI3098234T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4542408P 2008-04-16 2008-04-16
EP08251528 2008-04-25
EP16179121.5A EP3098234B1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation

Publications (1)

Publication Number Publication Date
SI3098234T1 true SI3098234T1 (sl) 2024-10-30

Family

ID=39717519

Family Applications (6)

Application Number Title Priority Date Filing Date
SI200932205T SI3098234T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931547A SI2808340T1 (sl) 2008-04-16 2009-04-16 Rekombinirani FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932094T SI3144318T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200930931T SI2268666T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932209T SI4015527T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931670A SI3045471T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo

Family Applications After (5)

Application Number Title Priority Date Filing Date
SI200931547A SI2808340T1 (sl) 2008-04-16 2009-04-16 Rekombinirani FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932094T SI3144318T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200930931T SI2268666T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932209T SI4015527T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931670A SI3045471T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo

Country Status (29)

Country Link
US (5) US8951967B2 (cg-RX-API-DMAC7.html)
EP (7) EP3098234B1 (cg-RX-API-DMAC7.html)
JP (7) JP2011519359A (cg-RX-API-DMAC7.html)
KR (5) KR20180095140A (cg-RX-API-DMAC7.html)
CN (3) CN105906703A (cg-RX-API-DMAC7.html)
AR (1) AR071479A1 (cg-RX-API-DMAC7.html)
AU (5) AU2009237479B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0910461B8 (cg-RX-API-DMAC7.html)
CA (1) CA2725257A1 (cg-RX-API-DMAC7.html)
CY (1) CY1115413T1 (cg-RX-API-DMAC7.html)
DK (6) DK4015527T3 (cg-RX-API-DMAC7.html)
ES (5) ES2989729T3 (cg-RX-API-DMAC7.html)
FI (4) FI3098234T3 (cg-RX-API-DMAC7.html)
FR (3) FR17C1020I2 (cg-RX-API-DMAC7.html)
HR (5) HRP20241187T1 (cg-RX-API-DMAC7.html)
HU (9) HUE071059T2 (cg-RX-API-DMAC7.html)
IL (2) IL208538A (cg-RX-API-DMAC7.html)
LT (8) LT2808340T (cg-RX-API-DMAC7.html)
MX (3) MX355457B (cg-RX-API-DMAC7.html)
NO (4) NO2017025I1 (cg-RX-API-DMAC7.html)
NZ (1) NZ588381A (cg-RX-API-DMAC7.html)
PL (6) PL2268666T3 (cg-RX-API-DMAC7.html)
PT (6) PT3098234T (cg-RX-API-DMAC7.html)
RU (3) RU2682270C2 (cg-RX-API-DMAC7.html)
SA (1) SA109300228B1 (cg-RX-API-DMAC7.html)
SI (6) SI3098234T1 (cg-RX-API-DMAC7.html)
TW (1) TWI488640B (cg-RX-API-DMAC7.html)
WO (1) WO2009127826A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201007373B (cg-RX-API-DMAC7.html)

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DK2621517T4 (da) 2010-09-29 2023-11-20 Ferring Bv Sammensætning til anvendelse i behandlingen af infertilitet
JP5918697B2 (ja) 2010-10-15 2016-05-18 Ｊｃｒファーマ株式会社 糖鎖の非還元末端がマンノース残基である糖蛋白質の製造方法
ES2693273T3 (es) * 2011-03-31 2018-12-10 Ferring B.V. Preparación farmacéutica
WO2012168680A1 (en) 2011-06-06 2012-12-13 Ferring B.V. Pharmaceutical preparation comprising recombinant fsh
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JP2018500934A (ja) * 2014-12-22 2018-01-18 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｍｐ依存性シアリダーゼ活性
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EP3382014A1 (en) 2017-03-29 2018-10-03 CEVEC Pharmaceuticals GmbH Recombinant glycoproteins with reduced antennary fucosylation
EP3441471A1 (en) 2017-08-08 2019-02-13 CEVEC Pharmaceuticals GmbH Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines
DK3973982T3 (da) 2017-09-01 2024-09-23 Ferring Bv Sammensætning til kontrolleret ovariestimulation
HUE071268T2 (hu) 2018-04-30 2025-08-28 Ferring Bv Készítmény szabályozott petefészek-stimuláláshoz
TWI846743B (zh) 2018-10-17 2024-07-01 荷蘭商菲林公司 用於控制性卵巢刺激之組成物及方法
WO2021081670A1 (en) * 2019-11-01 2021-05-06 The University Of British Columbia Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh) 2020-12-09 2022-10-01 荷蘭商菲林公司 用於受控的卵巢刺激之組成物及方法
AU2022451605A1 (en) 2022-04-01 2024-09-26 Ferring B.V. Mixed protocol for treatment of infertility
CA3255772A1 (en) 2022-05-26 2023-11-30 Ferring B.V. Compositions and methods of treating infertility in men
KR20250033230A (ko) 2022-07-08 2025-03-07 훼링 비.브이. 자궁내 인공수정(iui)을 위한 조성물 및 방법
AR133300A1 (es) 2023-07-20 2025-09-17 Ferring Bv Micropartículas cargadas con fármaco de liberación prolongada

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ES2693273T3 (es) 2011-03-31 2018-12-10 Ferring B.V. Preparación farmacéutica
WO2012168680A1 (en) 2011-06-06 2012-12-13 Ferring B.V. Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
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Also Published As

Publication number Publication date
LTPA2025525I1 (cg-RX-API-DMAC7.html) 2025-07-25
LTPA2017029I1 (lt) 2017-10-10
PT3098234T (pt) 2024-10-21
FI4015527T3 (fi) 2025-04-29
KR20170110741A (ko) 2017-10-11
NO2025032I1 (no) 2025-07-14
AU2017225020A1 (en) 2017-09-28
KR20190092608A (ko) 2019-08-07
BRPI0910461B8 (pt) 2021-05-25
PT3144318T (pt) 2020-11-04
EP2268666A1 (en) 2011-01-05
SA109300228B1 (ar) 2014-04-08
EP4015527B1 (en) 2025-01-22
PL3045471T3 (pl) 2017-10-31
NZ588381A (en) 2012-05-25
SI2808340T1 (sl) 2016-12-30
KR20160056960A (ko) 2016-05-20
US9771407B2 (en) 2017-09-26
AU2014203277A1 (en) 2014-07-24
LT3098234T (lt) 2024-09-10
JP2011519359A (ja) 2011-07-07
MX2010011343A (es) 2011-01-20
PL4015527T3 (pl) 2025-05-26
FIC20250025I1 (fi) 2025-07-11
MX355457B (es) 2018-04-19
DK4015527T3 (da) 2025-04-14
ES3023526T3 (en) 2025-06-02
HK1199039A1 (en) 2015-06-19
US20240327487A1 (en) 2024-10-03
DK2268666T3 (da) 2014-05-12
HK1146284A1 (en) 2011-05-20
ES2610277T3 (es) 2017-04-26
HRP20140535T1 (hr) 2014-07-18
US8951967B2 (en) 2015-02-10
US20180079794A1 (en) 2018-03-22
HUE030652T2 (en) 2017-05-29
JP2024038000A (ja) 2024-03-19
LT4015527T (lt) 2025-04-10
SI4015527T1 (sl) 2025-05-30
JP2022031652A (ja) 2022-02-22
US20110105398A1 (en) 2011-05-05
EP3144318B1 (en) 2020-09-23
HRP20161520T1 (hr) 2016-12-30
IL208538A0 (en) 2010-12-30
RU2014141994A3 (cg-RX-API-DMAC7.html) 2018-05-28
FR25C1003I1 (fr) 2025-02-28
SI3045471T1 (sl) 2017-07-31
US20150065695A1 (en) 2015-03-05
RU2745557C3 (ru) 2021-12-10
ES2989729T3 (es) 2024-11-27
NO2017050I1 (no) 2017-09-28
HUS2500029I1 (hu) 2025-07-28
FI3098234T3 (fi) 2024-10-31
RU2745557C1 (ru) 2021-03-29
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