SG155251A1 - Process for production of 1-(3-(2-(1-benzothiophen-5-yl)- ethoxy)propyl)azetidin-3-ol or salts thereof - Google Patents
Process for production of 1-(3-(2-(1-benzothiophen-5-yl)- ethoxy)propyl)azetidin-3-ol or salts thereofInfo
- Publication number
- SG155251A1 SG155251A1 SG200905724-1A SG2009057241A SG155251A1 SG 155251 A1 SG155251 A1 SG 155251A1 SG 2009057241 A SG2009057241 A SG 2009057241A SG 155251 A1 SG155251 A1 SG 155251A1
- Authority
- SG
- Singapore
- Prior art keywords
- benzothiophen
- azetidin
- ethoxy
- propyl
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005090831 | 2005-03-28 | ||
| JP2005174738 | 2005-06-15 | ||
| JP2005206808 | 2005-07-15 | ||
| JP2005230666 | 2005-08-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG155251A1 true SG155251A1 (en) | 2009-09-30 |
Family
ID=37053344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200905724-1A SG155251A1 (en) | 2005-03-28 | 2006-03-27 | Process for production of 1-(3-(2-(1-benzothiophen-5-yl)- ethoxy)propyl)azetidin-3-ol or salts thereof |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7951963B2 (pl) |
| EP (4) | EP2210884B1 (pl) |
| JP (1) | JP5031554B2 (pl) |
| KR (2) | KR101337382B1 (pl) |
| CN (1) | CN101151257B (pl) |
| AT (2) | ATE546443T1 (pl) |
| AU (1) | AU2006229271B2 (pl) |
| BR (1) | BRPI0609496C8 (pl) |
| CA (2) | CA2799659C (pl) |
| CY (3) | CY1112956T1 (pl) |
| DK (2) | DK2248809T3 (pl) |
| ES (3) | ES2380443T3 (pl) |
| IL (2) | IL186044A (pl) |
| MX (1) | MX2007011938A (pl) |
| NO (3) | NO340071B1 (pl) |
| NZ (2) | NZ583580A (pl) |
| PL (3) | PL2248809T3 (pl) |
| PT (3) | PT2248809E (pl) |
| SG (1) | SG155251A1 (pl) |
| SI (3) | SI2348022T1 (pl) |
| WO (1) | WO2006104088A1 (pl) |
| ZA (1) | ZA200708262B (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0213393B8 (pt) | 2001-10-19 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica |
| PL2248809T3 (pl) * | 2005-03-28 | 2012-10-31 | Toyama Chemical Co Ltd | 3-[2-(Benzo[b]tiofen-5-ylo)-etoksy]-propaniany alkilu jako związki pośrednie w wytwarzaniu pochodnych azetydyn-3-olu |
| JP4902247B2 (ja) * | 2005-04-08 | 2012-03-21 | 富山化学工業株式会社 | ２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体 |
| CA2869945C (en) | 2006-04-07 | 2018-01-23 | Vertex Pharmaceuticals Incorporated | Modulators of atp-binding cassette transporters |
| US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| US7645789B2 (en) | 2006-04-07 | 2010-01-12 | Vertex Pharmaceuticals Incorporated | Indole derivatives as CFTR modulators |
| SI2048145T1 (sl) * | 2006-08-04 | 2011-04-29 | Toyama Chemical Co Ltd | Spodbujevalec aktivnosti proteinske kinaze c, vsebujoäś derivat alkilnega etra ali sol le-tega |
| US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
| JP5763313B2 (ja) * | 2009-09-03 | 2015-08-12 | 富山化学工業株式会社 | ２−（１−ベンゾチオフェン−５−イル）エタノールの製造法 |
| JP5592205B2 (ja) * | 2009-09-03 | 2014-09-17 | 富山化学工業株式会社 | （１−ベンゾチオフェン−５−イル）酢酸またはその塩の製造法 |
| US8802868B2 (en) | 2010-03-25 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide |
| MX2012012204A (es) * | 2010-04-22 | 2012-12-05 | Vertex Pharma | Proceso para producir compuestos de cicloalquilcarboxamido-indol. |
| JP6004307B2 (ja) * | 2010-07-26 | 2016-10-05 | 富山化学工業株式会社 | ３−（２−（１−ベンゾチオフェン−５−イル）エトキシ）プロピオン酸の塩またはその水和物およびその製造法 |
| BR112013022282B1 (pt) | 2011-03-02 | 2019-03-26 | Bayer Intellectual Property Gmbh | Processo para a preparação de derivados de ácidos aril- e heteroaril acético |
| WO2013047786A1 (ja) | 2011-09-30 | 2013-04-04 | 日本化成株式会社 | 重合性無機粒子分散剤、該重合性無機粒子分散剤を含む無機有機複合粒子、および無機有機樹脂複合材 |
| TR201907882T4 (tr) | 2012-02-22 | 2019-06-21 | Fujifilm Toyama Chemical Co Ltd | 1-(3-(2-(1-Benzotiofen-5-il)etoksi)propil)azetidin-3-olü veya onun tuzunu içeren katı farmasötik bileşim |
| AR092857A1 (es) | 2012-07-16 | 2015-05-06 | Vertex Pharma | Composiciones farmaceuticas de (r)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-il)-n-(1-(2,3-dihidroxipropil)-6-fluoro-2-(1-hidroxi-2-metilpropan-2-il)-1h-indol-5-il)ciclopropancarboxamida y administracion de las mismas |
| EP3100725B1 (en) | 2014-01-31 | 2020-05-06 | FUJIFILM Toyama Chemical Co., Ltd. | Post nerve injury rehabilitation effect-enhancing agent comprising an alkyl ether derivative or a salt thereof |
| CN110840847B (zh) | 2014-04-15 | 2022-07-29 | 沃泰克斯药物股份有限公司 | 用于治疗囊性纤维化跨膜传导调节因子介导的疾病的药物组合物 |
| US11236062B2 (en) | 2016-03-31 | 2022-02-01 | Fujifilm Toyama Chemical Co., Ltd. | Method for producing 5-(bromomethyl)-1-benzothiophene |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL72070A (en) | 1983-06-20 | 1988-11-30 | Merck & Co Inc | 2-sulfamoylbenzo(b)-thiophene derivatives,their preparation and pharmaceutical compositions containing them |
| ZA844616B (en) | 1983-06-20 | 1986-02-26 | Merck & Co Inc | 2-sulfamoylbenzo(b)thiophene derivatives for the treatment of elevated intraocular pressure |
| US4668697A (en) | 1983-10-31 | 1987-05-26 | Merck & Co., Inc. | Elevated intraocular pressure lowering benzo-[b]-thiophene-2-sulfonamide derivatives, compositions, and method of use therefor |
| CH673100A5 (pl) | 1987-08-10 | 1990-02-15 | Josef Paul Huser | |
| JPH04182463A (ja) | 1990-11-17 | 1992-06-30 | Sumitomo Seika Chem Co Ltd | ハロゲノチオフェノール類およびその誘導体の製造方法 |
| JPH05140086A (ja) | 1991-09-26 | 1993-06-08 | Sumitomo Seika Chem Co Ltd | ハロゲノチオフエノールの製造方法および精製方法 |
| JPH05178816A (ja) | 1991-12-28 | 1993-07-20 | Sumitomo Seika Chem Co Ltd | ハロゲノチオフェノールの製造方法 |
| JP2641363B2 (ja) | 1992-04-22 | 1997-08-13 | 三共株式会社 | 新規なフェネチルアルコール及びその製法 |
| GB9404775D0 (en) | 1994-03-11 | 1994-04-27 | Payne P P Ltd | Improvements in or relating to article tagging |
| JPH08143533A (ja) | 1994-11-24 | 1996-06-04 | Sumitomo Seika Chem Co Ltd | ハロチオフェノール類の製造方法 |
| JPH1043967A (ja) | 1996-08-06 | 1998-02-17 | Calsonic Corp | カシメ装置 |
| AU6519798A (en) | 1997-03-31 | 1998-10-22 | Toyama Chemical Co. Ltd. | Process for producing 2-(benzo{b}thiophen-5-yl)-2-hydroxyacetic acid derivatives, optically active compounds thereof, or salts of both |
| GB9706574D0 (en) | 1997-04-01 | 1997-05-21 | Zeneca Ltd | Cyano substituted cycloalkanes |
| JPH1112238A (ja) | 1997-06-23 | 1999-01-19 | Kao Corp | １−（β−ヒドロキシエチル）−２，５−ジアミノベンゼン又はその塩の製造法 |
| JPH1143455A (ja) | 1997-07-25 | 1999-02-16 | Mitsubishi Chem Corp | ハロゲン化アルコールの製造方法 |
| WO1999031056A1 (fr) | 1997-12-12 | 1999-06-24 | Toyama Chemical Co., Ltd. | Derives d'ether alcoylique ou leurs sels, et antagonistes du calcium les contenant |
| EP0993105B1 (en) | 1998-10-07 | 2003-01-08 | STMicroelectronics S.r.l. | Control of power transfer in a flyback converter by modulating the off-phase in function of the load |
| JP4182463B2 (ja) | 2000-07-19 | 2008-11-19 | 富士電機デバイステクノロジー株式会社 | 磁気ディスク評価装置およびその方法 |
| WO2002100850A1 (fr) | 2001-06-08 | 2002-12-19 | Kuraray Co., Ltd. | Procedes de preparation de composes heterocycliques |
| BRPI0213393B8 (pt) | 2001-10-19 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica |
| CA2521648C (en) * | 2003-04-17 | 2012-07-03 | Toyama Chemical Co., Ltd. | Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof |
| JP2005012291A (ja) | 2003-06-17 | 2005-01-13 | National Institute Of Information & Communication Technology | Ｔｖ会議用モバイル動画通信端末 |
| US20050032873A1 (en) | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
| WO2005019200A2 (en) | 2003-08-14 | 2005-03-03 | Icos Corporation | Aryl piperidine derivatives as vla-1 integrin antagonists and uses thereof |
| PL2248809T3 (pl) | 2005-03-28 | 2012-10-31 | Toyama Chemical Co Ltd | 3-[2-(Benzo[b]tiofen-5-ylo)-etoksy]-propaniany alkilu jako związki pośrednie w wytwarzaniu pochodnych azetydyn-3-olu |
| MX2008013728A (es) | 2006-04-26 | 2009-01-07 | Toyama Chemical Co Ltd | Inductor de neurogenesis o agente terapeutico de neuropatia que abarca el derivado del eter alkilico o sal del mismo. |
-
2006
- 2006-03-27 PL PL10007872T patent/PL2248809T3/pl unknown
- 2006-03-27 EP EP10002020A patent/EP2210884B1/en active Active
- 2006-03-27 PL PL10002020T patent/PL2210884T3/pl unknown
- 2006-03-27 CN CN2006800102653A patent/CN101151257B/zh active Active
- 2006-03-27 ES ES10002020T patent/ES2380443T3/es active Active
- 2006-03-27 ZA ZA200708262A patent/ZA200708262B/xx unknown
- 2006-03-27 SI SI200631556T patent/SI2348022T1/sl unknown
- 2006-03-27 DK DK10007872.4T patent/DK2248809T3/da active
- 2006-03-27 CA CA2799659A patent/CA2799659C/en active Active
- 2006-03-27 EP EP10007872A patent/EP2248809B1/en active Active
- 2006-03-27 MX MX2007011938A patent/MX2007011938A/es active IP Right Grant
- 2006-03-27 NZ NZ583580A patent/NZ583580A/en unknown
- 2006-03-27 BR BRPI0609496A patent/BRPI0609496C8/pt active IP Right Grant
- 2006-03-27 SG SG200905724-1A patent/SG155251A1/en unknown
- 2006-03-27 CA CA2600381A patent/CA2600381C/en active Active
- 2006-03-27 WO PCT/JP2006/306127 patent/WO2006104088A1/ja active Application Filing
- 2006-03-27 AT AT10002020T patent/ATE546443T1/de active
- 2006-03-27 EP EP06730075A patent/EP1864978A4/en not_active Withdrawn
- 2006-03-27 EP EP11002265A patent/EP2348022B1/en active Active
- 2006-03-27 AT AT10007872T patent/ATE557020T1/de active
- 2006-03-27 NZ NZ561672A patent/NZ561672A/en unknown
- 2006-03-27 SI SI200631383T patent/SI2248809T1/sl unknown
- 2006-03-27 PT PT10007872T patent/PT2248809E/pt unknown
- 2006-03-27 SI SI200631324T patent/SI2210884T1/sl unknown
- 2006-03-27 US US11/909,809 patent/US7951963B2/en active Active
- 2006-03-27 AU AU2006229271A patent/AU2006229271B2/en active Active
- 2006-03-27 PT PT110022654T patent/PT2348022E/pt unknown
- 2006-03-27 PL PL11002265T patent/PL2348022T3/pl unknown
- 2006-03-27 KR KR1020127032936A patent/KR101337382B1/ko active IP Right Grant
- 2006-03-27 PT PT10002020T patent/PT2210884E/pt unknown
- 2006-03-27 ES ES10007872T patent/ES2384312T3/es active Active
- 2006-03-27 KR KR1020077024039A patent/KR101283930B1/ko active IP Right Grant
- 2006-03-27 JP JP2007510482A patent/JP5031554B2/ja active Active
- 2006-03-27 ES ES11002265T patent/ES2398934T3/es active Active
- 2006-03-27 DK DK10002020.5T patent/DK2210884T3/da active
-
2007
- 2007-09-12 NO NO20074618A patent/NO340071B1/no unknown
- 2007-09-18 IL IL186044A patent/IL186044A/en active IP Right Grant
-
2011
- 2011-01-06 US US12/985,616 patent/US8273902B2/en active Active
- 2011-07-21 IL IL214245A patent/IL214245A/en active IP Right Grant
-
2012
- 2012-05-08 CY CY20121100434T patent/CY1112956T1/el unknown
- 2012-06-27 CY CY20121100566T patent/CY1112885T1/el unknown
-
2013
- 2013-01-25 CY CY20131100075T patent/CY1113571T1/el unknown
-
2016
- 2016-09-07 NO NO20161419A patent/NO340420B1/no unknown
- 2016-09-07 NO NO20161418A patent/NO340366B1/no unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG155251A1 (en) | Process for production of 1-(3-(2-(1-benzothiophen-5-yl)- ethoxy)propyl)azetidin-3-ol or salts thereof | |
| SI1801082T1 (sl) | Postopek za izdelavo anorganskih vlaken | |
| EP2040910A4 (en) | CALING METHOD FOR PRODUCING AN OPTICAL FILM | |
| PL2088218T3 (pl) | Blacha stalowa gruba o wysokim module Younga i sposób jej wytwarzania | |
| ZA200809453B (en) | Process for producing bleached pulp | |
| EP1976844A4 (en) | IMPROVED METHOD FOR PURE DULOXETIN HYDROCHLORIDE | |
| EP2067348A4 (en) | VARIABLE CONVERSATION RECORDING METHOD | |
| PT3061866T (pt) | Processo de fabrico de papel ou cartão | |
| EP1900720A4 (en) | PROCESS FOR PRODUCING SUBSTITUTED CYCLOPENTANONE | |
| ZA200805231B (en) | Process for making diaryl carbonate | |
| SG136920A1 (en) | Process for producing methionine | |
| FR2910500B1 (fr) | Procede de fabrication d'un papier calque | |
| TW200734321A (en) | Benzo [b] thiophen derivatives and a process for producing benzo [b] thiophen derivatives | |
| EP2332932A4 (en) | NEW CRYSTALLINE FORMS OF 4- (2-AMINOPYRIDIN-4-YL) -3- (4-fluoro-PHENYL) -1- (1,4,5,6-TETRAHYDRO-6-OXOPYRIDAZIN-3-YL) -1H-PYRAZOLE -METHANESULPHONATE AND METHOD OF MANUFACTURING THEREOF | |
| EP1930325A4 (en) | METHOD FOR PRODUCING AN OPTICALLY ACTIVE PIPERAZINE COMPOUND | |
| DK2348022T3 (da) | Fremgangsmåde til fremstilling af 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol eller salte deraf | |
| EP2226310A4 (en) | PROCESS FOR PRODUCING 2- (1-HYDROXYALKYL) CYCLOALCANONE | |
| EP2077259A4 (en) | PROCESS FOR THE PRODUCTION OF 2,6-DIMETHYL-1-NAPHTHALDEHYDE | |
| EP2226325A4 (en) | PROCESS FOR THE PRODUCTION OF 4- (PHENYL-SUBSTITUTED) HEXAHYDROPYRIDOÝ2,1-CÝÝ1,4¨OXAZIN-6-ONE | |
| EP1953150A4 (en) | PROCESS FOR THE MANUFACTURE OF 2- (4-METHYL-2-PHENYLPIPERAZIN-1-YL) PYRIDINE-3-METHANOL | |
| ZA200810321B (en) | Crystalline (3-cyano-1H-indol-7-yl)-[4-(4-fluorophenethyl) piperazin-1-yl]methanone phosphate | |
| PL379536A3 (pl) | Sposób wytwarzania 3-[2-(2-dipropyloaminoetylo)-6-nitrofenylo]-2-oksopropionianu etylu |