SE8804629A - - Google Patents
Info
- Publication number
- SE8804629A SE8804629A SE8804629A SE8804629A SE8804629A SE 8804629 A SE8804629 A SE 8804629A SE 8804629 A SE8804629 A SE 8804629A SE 8804629 A SE8804629 A SE 8804629A SE 8804629 A SE8804629 A SE 8804629A
- Authority
- SE
- Sweden
- Prior art keywords
- compound
- cyclopropylmethoxy
- sulfinyl
- benzimidazole
- pyridinyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- DIUOJMLXZJHNDR-UHFFFAOYSA-N 2-[[4-(cyclopropylmethoxy)pyridin-2-yl]methylsulfinyl]-6-fluoro-1h-benzimidazole Chemical compound N=1C2=CC(F)=CC=C2NC=1S(=O)CC(N=CC=1)=CC=1OCC1CC1 DIUOJMLXZJHNDR-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
Priority Applications (67)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19888804629A SE8804629D0 (sv) | 1988-12-22 | 1988-12-22 | New therapeutically active compounds |
AR89315705A AR248136A1 (es) | 1988-12-22 | 1989-12-18 | Procedimiento e intermediarios para la preparacion de 5 5 5 5 5 |
IE894048A IE894048L (en) | 1988-12-22 | 1989-12-18 | New therapeutically active compound and a process for its¹preparation |
EG62189A EG19303A (en) | 1988-12-22 | 1989-12-18 | Process for preparing of new therapeutically active compound |
IE405089A IE64199B1 (en) | 1988-12-22 | 1989-12-18 | Compound with gastric acid inhibitory effect and process for its preparation |
EG61989A EG19302A (en) | 1988-12-22 | 1989-12-18 | Compound with gastric acid inhibitory effect and process for its preparation |
CA002005986A CA2005986C (en) | 1988-12-22 | 1989-12-19 | Benzimidazole derivative with gastric acid inhibitory effect and process for its preparation |
IL92798A IL92798A0 (en) | 1988-12-22 | 1989-12-19 | Benzimidazole derivatives,process for their preparation and pharmaceutical compositions containing them |
IL9279989A IL92799A (en) | 1988-12-22 | 1989-12-19 | History of benzimidazole, its preparation process and gastric acid-containing medicinal preparations |
NZ231874A NZ231874A (en) | 1988-12-22 | 1989-12-19 | 4-fluoro-2-(((4-methoxy-2-pyridinyl)methyl)sulphinyl)-1h-benzimidazole and pharmaceutical compositions |
NZ231872A NZ231872A (en) | 1988-12-22 | 1989-12-19 | 5-fluoro-2-(((4-cyclopropylmethoxy-2-pyridinyl)methyl)sulphinyl)-1h-benzimidazole, various pyridine intermediates and pharmaceutical compositions |
GR890100838A GR1002252B (en) | 1988-12-22 | 1989-12-19 | A novel therapeutic active compound and preparation method therefore. |
CA002005980A CA2005980C (en) | 1988-12-22 | 1989-12-19 | Benzimidazole derivative with gastric acid inhibitory effect and process for its preparation |
GR890100833A GR1000316B (el) | 1988-12-22 | 1989-12-19 | Μεθοδος για την παρασκευη μιας ενωσης με γαστρικη ανασταλτικη δραση. |
PH39731A PH27446A (en) | 1988-12-22 | 1989-12-19 | Compound with gastric acid inhibitory effect |
PH39732A PH27400A (en) | 1988-12-22 | 1989-12-19 | New therapeutically active compound and method of use thereof |
DE68917937T DE68917937T2 (de) | 1988-12-22 | 1989-12-20 | Verbindungen mit magensäureinhibitorwirkung und verfahren zur herstellung. |
AU48175/90A AU634741B2 (en) | 1988-12-22 | 1989-12-20 | Benzimidazole and (4-cyclopropyl methoxy pyridinyl) linked derivatives |
EP90901079A EP0449940B1 (en) | 1988-12-22 | 1989-12-20 | New therapeutically active compound and a process for its preparation |
JP2501536A JP2793905B2 (ja) | 1988-12-22 | 1989-12-20 | 胃酸抑制効果を有する化合物およびその製法 |
KR1019900701827A KR910700248A (ko) | 1988-12-22 | 1989-12-20 | 위산 분비 억제 효과를 갖는 화합물 및 그의 제조 방법 |
AT90901079T ATE127799T1 (de) | 1988-12-22 | 1989-12-20 | Therapeutisch aktive verbindung und verfahren zu deren herstellung. |
AT90901073T ATE110723T1 (de) | 1988-12-22 | 1989-12-20 | Verbindungen mit magensäureinhibitorwirkung und verfahren zur herstellung. |
US07/453,960 US5025024A (en) | 1988-12-22 | 1989-12-20 | Therapeutically active fluoro-substituted compound |
ZA899795A ZA899795B (en) | 1988-12-22 | 1989-12-20 | Compound with gastric acid inhibitory effect and process for its preparation |
PCT/SE1989/000740 WO1990006925A1 (en) | 1988-12-22 | 1989-12-20 | New therapeutically active compound and a process for its preparation |
HU901095A HUT57204A (en) | 1988-12-22 | 1989-12-20 | Process for producing 4-fluoro-2-///4-methoxy-2-pyridinyl/-methyl/-sulfinyl/-1h-benzimidazol with gastric acid secration-diminishing activity and pharmaceutical compositions containing them |
DD89335980A DD296078A5 (de) | 1988-12-22 | 1989-12-20 | Verfahren zur herstellung von benzimidazolen |
SU894895789A RU2073676C1 (ru) | 1988-12-22 | 1989-12-20 | 5-фтор-2-*01([(4-циклопропилметокси-2-пиридинил)метил] сульфинил*01)-1h-бензимидазол или его физиологически приемлемая соль, фармкомпозиция на его основе и промежуточные соединения |
PCT/SE1989/000739 WO1990006924A1 (en) | 1988-12-22 | 1989-12-20 | Compound with gastric acid inhibitory effect and process for its preparation |
HU901084A HU205926B (en) | 1988-12-22 | 1989-12-20 | Process for producing new, pharmaceutically active 5-fluoro-2- 4-/cyclopropyl-methoxy/-2-pyridinyl-methyl-sulfinyl-1h-benzimidazol and pharmaceutical compositions containing them |
RO147866A RO110494B1 (ro) | 1988-12-22 | 1989-12-20 | Compus de benzimidazol activ terapeutic, procedeu de preparare, intermediar pentru acesta si compozitie farmaceutica, continand compusul de benzimidazol |
DD89335981A DD296079A5 (de) | 1988-12-22 | 1989-12-20 | Verfahren zur herstellung von benzimidazolen |
US07/454,047 US5008278A (en) | 1988-12-22 | 1989-12-20 | Therapeutically active compound and a process for its preparation |
ZA899794A ZA899794B (en) | 1988-12-22 | 1989-12-20 | New therapeutically active compound and a process for its preparation |
HU901095A HU205927B (en) | 1988-12-22 | 1989-12-20 | Process for producing 4-fluoro-2-///4-methoxy-2-piridinyl/-sulfinyl/-1h-benzimidazol of acid secretion inhibiting activity and pharmaceutical compositions containing them |
JP2501537A JP2793906B2 (ja) | 1988-12-22 | 1989-12-20 | 治療上活性な新規化合物およびその製法 |
DE68924273T DE68924273T2 (de) | 1988-12-22 | 1989-12-20 | Therapeutisch aktive verbindung und verfahren zu deren herstellung. |
AU48132/90A AU639429B2 (en) | 1988-12-22 | 1989-12-20 | Compound with gastric acid inhibitory effect and process for its preparation |
EP90901073A EP0449935B1 (en) | 1988-12-22 | 1989-12-20 | Compound with gastric acid inhibitory effect and process for its preparation |
PT92649A PT92649B (pt) | 1988-12-22 | 1989-12-21 | Processo para a preparacao do 4-fluoro-2-< { (4-metoxi-2-piridinil)-metil}-sulfinil>-1h-benzimidazol e de composicoes farmaceuticas que o contem |
CN89109587A CN1028231C (zh) | 1988-12-22 | 1989-12-21 | 具有新治疗活性的取代的苯并咪唑的制备方法 |
CN89109589A CN1028233C (zh) | 1988-12-22 | 1989-12-21 | 具有抑制胃酸作用的取代的苯并咪唑的制备方法 |
YU242689A YU46806B (sh) | 1988-12-22 | 1989-12-21 | 5-FLUORO-2-//(4-CIKLOPROPILMETOKSI-2-PIRINIDIL)METILSULFINIL/1h-BENZIMODAZOL I POSTUPAK ZA NJEGOVO DOBIJANJE |
MYPI89001835A MY129946A (en) | 1988-12-22 | 1989-12-21 | Compound with gastric acid inhibitory effect and process for its preparation. |
YU242789A YU47338B (sh) | 1988-12-22 | 1989-12-21 | Novo jedinjenje 4-fluoro-2-// (4-metoksi-2-piridinil)metil-/sulfinil/- 1h-benzimidazol i postupak za njegovo dobijanje |
PT92648A PT92648B (pt) | 1988-12-22 | 1989-12-21 | Processo para a preparacao do 5-fluoro-2-< { (4-ciclopropilmetoxi-2-piridinil)-metil}-sulfinil>-1h-benzimidazol e de composicoes farmaceuticas que o contem |
PL1989282922A PL160767B1 (pl) | 1988-12-22 | 1989-12-22 | Sposób wytwarzania nowego 4-fluoro-2- [(4-metoksypirydynylo-2)metylosulfinylo]--1 H-benzimidazolu PL PL |
PL1989282923A PL161150B1 (en) | 1988-12-22 | 1989-12-22 | Method for manufacturing new 5-fluoro-2-((4-cyclopropylmethoxy-pyridinilo-2) methylsulphynyl)-1h-benzimidazole |
CS897343A CS276361B6 (en) | 1988-12-22 | 1989-12-22 | 4-fluoro-2-//(4-methoxy-2-pyridyl)methyl/sulfinyl/ -1h - benzimidazole, process for its production and a pharmaceutical comprising said compound as an active component |
KR1019900701828A KR910700249A (ko) | 1988-12-22 | 1990-08-21 | 신규 치료학적 활성 화합물 및 그의 제조 방법 |
US07/633,007 US5039808A (en) | 1988-12-22 | 1990-12-20 | Therapeutically active cyclopropyl substituted compound |
BG94659A BG60102A3 (en) | 1988-12-22 | 1991-06-19 | Method for preparing of 5-fluoro-2[[(4-cyclopropylmethoxy-2-pyridyl)methyl]thionyl]-1h-ben zimidazole |
BG94657A BG60101A3 (en) | 1988-12-22 | 1991-06-19 | Method for preparing of 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]thionil]-1h-benzimidazo le |
NO912415A NO178337C (no) | 1988-12-22 | 1991-06-20 | Analogifremgangsmåte for fremstilling av terapeutisk aktiv 5-fluor-2[[(4-cyklopropyl-(metoksy-2-pyridinyl)metylÅsulfinylÅ-1H-benzimidazol og mellomprodukter |
FI913035A FI913035A0 (fi) | 1988-12-22 | 1991-06-20 | Ny terapeutiskt aktiv foerening och foerfarande foer dess framstaellning. |
NO912414A NO178336C (no) | 1988-12-22 | 1991-06-20 | Analogifremgangsmåte for fremstilling av en terapeutisk aktiv benzimidazolforbindelse og mellomprodukter |
FI913034A FI913034A0 (fi) | 1988-12-22 | 1991-06-20 | Foerening med magsyrainhiberande effekt och foerfarande foer dess framstaellning. |
DK122291A DK170800B1 (da) | 1988-12-22 | 1991-06-21 | Substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende derivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mave-tarmkanallidelser hos pattedyr samt intermediære forbindelser til |
DK122191A DK122191A (da) | 1988-12-22 | 1991-06-21 | Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme |
SU914895805A RU2042673C1 (ru) | 1988-12-22 | 1991-06-21 | 4-фтор-2-{([(4-метокси -2- пиридинил) метил]сульфинил}) -1н-бензимидазол или его физиологически приемлемые соли, способ их получения, фармацевтическая композиция, 4-фтор-2-меркапто-1н- бензимидазол и 4-фтор-2-{([(4-метокси -2-пиридинил) метил]тио}) -1н-бензимидазол |
HR920831A HRP920831A2 (en) | 1988-12-22 | 1992-10-02 | New therapeutically active compound and a process for the preparation eof |
LVP-93-691A LV10267B (en) | 1988-12-22 | 1993-06-28 | Compound with gastric acid inhibitory effect and process for its preparation |
LVP-93-860A LV10187B (en) | 1988-12-22 | 1993-06-30 | New therapeutically active compound and a process for its preparation |
LTIP1726A LT3914B (en) | 1988-12-22 | 1993-12-30 | Compound with gastric acid inhibitory effect and process for its preparation |
LTIP1721A LT3980B (en) | 1988-12-22 | 1993-12-30 | New therapeutically active compound and a process for its preparation |
FI954768A FI954768A0 (fi) | 1988-12-22 | 1995-10-06 | Välituotteina käyttökelpoiset 4-syklopropyylimetoksipyridiiniyhdisteet |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19888804629A SE8804629D0 (sv) | 1988-12-22 | 1988-12-22 | New therapeutically active compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8804629D0 SE8804629D0 (sv) | 1988-12-22 |
SE8804629A true SE8804629A (xx) | 1988-12-22 |
Family
ID=20374310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE19888804629A SE8804629D0 (sv) | 1988-12-22 | 1988-12-22 | New therapeutically active compounds |
Country Status (32)
Country | Link |
---|---|
US (2) | US5008278A (xx) |
EP (1) | EP0449940B1 (xx) |
JP (1) | JP2793906B2 (xx) |
KR (1) | KR910700249A (xx) |
CN (1) | CN1028231C (xx) |
AR (1) | AR248136A1 (xx) |
AT (1) | ATE127799T1 (xx) |
AU (1) | AU634741B2 (xx) |
BG (1) | BG60102A3 (xx) |
CA (1) | CA2005986C (xx) |
DD (2) | DD296079A5 (xx) |
DE (1) | DE68924273T2 (xx) |
DK (1) | DK170800B1 (xx) |
EG (1) | EG19303A (xx) |
FI (2) | FI913035A0 (xx) |
GR (1) | GR1002252B (xx) |
HR (1) | HRP920831A2 (xx) |
HU (2) | HU205926B (xx) |
IE (1) | IE894048L (xx) |
IL (1) | IL92798A0 (xx) |
LT (2) | LT3980B (xx) |
LV (1) | LV10187B (xx) |
NZ (1) | NZ231872A (xx) |
PH (1) | PH27400A (xx) |
PL (1) | PL161150B1 (xx) |
PT (1) | PT92648B (xx) |
RO (1) | RO110494B1 (xx) |
RU (2) | RU2073676C1 (xx) |
SE (1) | SE8804629D0 (xx) |
WO (1) | WO1990006925A1 (xx) |
YU (1) | YU46806B (xx) |
ZA (2) | ZA899794B (xx) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ244301A (en) * | 1991-09-20 | 1994-08-26 | Merck & Co Inc | Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds |
TNSN95063A1 (fr) * | 1994-05-27 | 1996-02-06 | Astra Ab | Nouveaux benzimidazoles substitues |
ES2100142T3 (es) * | 1994-07-08 | 2002-03-01 | Astrazeneca Ab | Forma de dosificacion en tabletas i constituida por unidades multiples. |
SE9402431D0 (sv) * | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
US6699885B2 (en) * | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6489346B1 (en) * | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
DE19758573C2 (de) * | 1997-11-26 | 2001-03-01 | Implex Hear Tech Ag | Fixationselement für ein implantierbares Mikrofon |
EP1004305B1 (en) * | 1998-04-20 | 2011-09-28 | Eisai R&D Management Co., Ltd. | Stabilized compositions containing benzimidazole-type compounds |
TWI243672B (en) | 1999-06-01 | 2005-11-21 | Astrazeneca Ab | New use of compounds as antibacterial agents |
JP4081273B2 (ja) | 1999-10-20 | 2008-04-23 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ベンズイミダゾール系化合物安定化方法 |
SE0000774D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
SE0101379D0 (sv) | 2001-04-18 | 2001-04-18 | Diabact Ab | Komposition som hämmar utsöndring av magsyra |
US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
SE0102993D0 (sv) | 2001-09-07 | 2001-09-07 | Astrazeneca Ab | New self emulsifying drug delivery system |
US20040006111A1 (en) * | 2002-01-25 | 2004-01-08 | Kenneth Widder | Transmucosal delivery of proton pump inhibitors |
EP1487820A1 (en) * | 2002-03-26 | 2004-12-22 | Dr. Reddy's Laboratories Ltd. | Crystalline forms of rabeprazole sodium |
SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
JP2006518751A (ja) * | 2003-02-20 | 2006-08-17 | サンタラス インコーポレイティッド | 胃酸の急速かつ持続的な抑制のための新規製剤、オメプラゾール制酸剤複合体−即時放出物 |
US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
AR045062A1 (es) * | 2003-07-18 | 2005-10-12 | Santarus Inc | Formulaciones farmaceuticas para inhibir la secrecion de acido y metodos para preparar y utilizarlas |
MXPA06000524A (es) * | 2003-07-18 | 2006-08-11 | Santarus Inc | Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido. |
AU2004314693B2 (en) | 2003-09-26 | 2011-04-07 | Alza Corporation | Drug coating providing high drug loading and methods for providing the same |
US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8541026B2 (en) | 2004-09-24 | 2013-09-24 | Abbvie Inc. | Sustained release formulations of opioid and nonopioid analgesics |
US7981908B2 (en) | 2005-05-11 | 2011-07-19 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acid secretion |
US7803817B2 (en) | 2005-05-11 | 2010-09-28 | Vecta, Ltd. | Composition and methods for inhibiting gastric acid secretion |
RU2467747C2 (ru) | 2006-07-25 | 2012-11-27 | Векта Лтд. | Композиции и способы для ингибирования секреции желудочной кислоты с использованием производных малых дикарбоновых кислот в сочетании с ppi |
US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
AU2009290712A1 (en) | 2008-09-09 | 2010-03-18 | Astrazeneca Ab | Method for delivering a pharmaceutical composition to patient in need thereof |
EA201290026A1 (ru) | 2009-06-25 | 2012-07-30 | Астразенека Аб | Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid) |
US20120294937A1 (en) | 2009-12-29 | 2012-11-22 | Novartis Ag | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
WO2011080502A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
WO2011080500A2 (en) | 2009-12-29 | 2011-07-07 | Orexo Ab | New pharmaceutical dosage form for the treatment of gastric acid-related disorders |
EP2601947A1 (en) | 2011-12-05 | 2013-06-12 | Abo Bakr Mohammed Ali Al-Mehdar | Fixed-dose combination for treatment of helicobacter pylori associated diseases |
CN104519888A (zh) | 2011-12-28 | 2015-04-15 | 波曾公司 | 用于递送奥美拉唑和乙酰水杨酸的改良组合物和方法 |
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SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
IN148930B (xx) * | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
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CH644116A5 (de) * | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
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SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
HU195220B (en) * | 1983-05-03 | 1988-04-28 | Byk Gulden Lomberg Chem Fqb | Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them |
JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
JPS6150979A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
AU568441B2 (en) * | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
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JPS6261978A (ja) * | 1985-09-12 | 1987-03-18 | Otsuka Pharmaceut Co Ltd | 5−フルオロ−1h−ベンズイミダゾ−ル誘導体 |
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JPS62201884A (ja) * | 1986-02-28 | 1987-09-05 | Tokyo Tanabe Co Ltd | ベンズイミダゾール誘導体及びその製造法 |
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1988
- 1988-12-22 SE SE19888804629A patent/SE8804629D0/xx unknown
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1989
- 1989-12-18 IE IE894048A patent/IE894048L/xx unknown
- 1989-12-18 AR AR89315705A patent/AR248136A1/es active
- 1989-12-18 EG EG62189A patent/EG19303A/xx active
- 1989-12-19 NZ NZ231872A patent/NZ231872A/en unknown
- 1989-12-19 GR GR890100838A patent/GR1002252B/el unknown
- 1989-12-19 CA CA002005986A patent/CA2005986C/en not_active Expired - Lifetime
- 1989-12-19 IL IL92798A patent/IL92798A0/xx not_active IP Right Cessation
- 1989-12-19 PH PH39732A patent/PH27400A/en unknown
- 1989-12-20 AU AU48175/90A patent/AU634741B2/en not_active Ceased
- 1989-12-20 RU SU894895789A patent/RU2073676C1/ru active
- 1989-12-20 US US07/454,047 patent/US5008278A/en not_active Expired - Lifetime
- 1989-12-20 RO RO147866A patent/RO110494B1/ro unknown
- 1989-12-20 HU HU901084A patent/HU205926B/hu not_active IP Right Cessation
- 1989-12-20 EP EP90901079A patent/EP0449940B1/en not_active Expired - Lifetime
- 1989-12-20 DD DD89335981A patent/DD296079A5/de not_active IP Right Cessation
- 1989-12-20 ZA ZA899794A patent/ZA899794B/xx unknown
- 1989-12-20 DD DD89335980A patent/DD296078A5/de not_active IP Right Cessation
- 1989-12-20 ZA ZA899795A patent/ZA899795B/xx unknown
- 1989-12-20 AT AT90901079T patent/ATE127799T1/de not_active IP Right Cessation
- 1989-12-20 DE DE68924273T patent/DE68924273T2/de not_active Expired - Fee Related
- 1989-12-20 WO PCT/SE1989/000740 patent/WO1990006925A1/en active Application Filing
- 1989-12-20 JP JP2501537A patent/JP2793906B2/ja not_active Expired - Fee Related
- 1989-12-20 HU HU901095A patent/HU205927B/hu not_active IP Right Cessation
- 1989-12-21 PT PT92648A patent/PT92648B/pt not_active IP Right Cessation
- 1989-12-21 YU YU242689A patent/YU46806B/sh unknown
- 1989-12-21 CN CN89109587A patent/CN1028231C/zh not_active Expired - Fee Related
- 1989-12-22 PL PL1989282923A patent/PL161150B1/pl unknown
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1990
- 1990-08-21 KR KR1019900701828A patent/KR910700249A/ko not_active Application Discontinuation
- 1990-12-20 US US07/633,007 patent/US5039808A/en not_active Expired - Lifetime
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1991
- 1991-06-19 BG BG94659A patent/BG60102A3/xx unknown
- 1991-06-20 FI FI913035A patent/FI913035A0/fi not_active Application Discontinuation
- 1991-06-21 RU SU914895805A patent/RU2042673C1/ru active
- 1991-06-21 DK DK122291A patent/DK170800B1/da not_active IP Right Cessation
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1992
- 1992-10-02 HR HR920831A patent/HRP920831A2/hr not_active Application Discontinuation
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1993
- 1993-06-30 LV LVP-93-860A patent/LV10187B/en unknown
- 1993-12-30 LT LTIP1721A patent/LT3980B/lt not_active IP Right Cessation
- 1993-12-30 LT LTIP1726A patent/LT3914B/lt not_active IP Right Cessation
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1995
- 1995-10-06 FI FI954768A patent/FI954768A0/fi not_active Application Discontinuation
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